Focus on Molecules: Interleukin-1: A master regulator of the corneal response to injury

Experimental Eye Research

Volumn 89, Issue 2, 2009, Pages 124-125

  Wilson, Steven E ^a   Esposito, Andrew ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

apoptosis; corneal inflammation; corneal wound healing; interleukin 1; interleukin 1 receptor antagonist; myofibroblasts

Indexed keywords

BETA DEFENSIN 2; EPIDERMAL GROWTH FACTOR; FAS LIGAND; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RECEPTOR TYPE II; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; KERATINOCYTE GROWTH FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; CELL SURVIVAL; CORNEA CELL; CORNEA INJURY; CORNEA STROMA; CORNEA ULCER; CYTOKINE PRODUCTION; HERPES SIMPLEX KERATITIS; HUMAN; INFLAMMATION; MYOFIBROBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SHORT SURVEY; STEVENS JOHNSON SYNDROME; WOUND HEALING;

ANIMALS; CORNEA; HUMANS; INTERLEUKIN-1; KERATITIS; MODELS, MOLECULAR; RABBITS; WOUND HEALING;

EID: 67650407493     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2009.02.011     Document Type: Short Survey

References (4)

1. Arend W.P., Palmer G., and Gabay C. IL-1, IL-18, and IL-33 families of cytokines. Immunol. Rev. 223 (2008) 20-38
2. Dana R. Comparison of topical interleukin-1 vs tumor necrosis factor-alpha blockade with corticosteroid therapy on murine corneal inflammation, neovascularization, and transplant survival. Trans. Am. Ophthalmol. Soc. 105 (2007) 330-343
3. Stapleton W.M., Chaurasia S., Medeiros F.W., Mohan R.R., Sinha S., and Wilson S.E. Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea. Exp. Eye Res. 86 (2008) 753-757
4. Wilson S.E., Mohan R.R., Mohan R.R., Ambrósio Jr. R., Hong J., and Lee J. The corneal wound healing response: cytokine-mediated interaction of the epithelium, stroma, and inflammatory cells. Prog. Retin. Eye Res. 20 (2001) 625-637