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Volumn 48, Issue 3, 2009, Pages 257-267

Pediatric inflammatory bowel diseases and the risk of lymphoma: Should we revise our treatment strategies?

Author keywords

Anti TNF; Biologicals; Crohn; Inflammatory bowel disease; Lymphoma; Pediatric

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; CORTICOSTEROID; IMMUNOGLOBULIN G1; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; METHOTREXATE; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL PRODUCT; IMMUNOSUPPRESSIVE AGENT;

EID: 67650400522     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e31818cf555     Document Type: Review
Times cited : (43)

References (82)
  • 1
    • 34248136340 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Clinical aspects and established and evolving therapies
    • Baumgart DC, Sandborn WJ. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 2007; 369:1641-57.
    • (2007) Lancet , vol.369 , pp. 1641-1657
    • Baumgart, D.C.1    Sandborn, W.J.2
  • 2
    • 14844331036 scopus 로고    scopus 로고
    • Can we alter the natural history of Crohn disease in children?
    • Hyams JS, Markowitz JF. Can we alter the natural history of Crohn disease in children? J Pediatr Gastroenterol Nutr 2005;40:262-72.
    • (2005) J Pediatr Gastroenterol Nutr , vol.40 , pp. 262-272
    • Hyams, J.S.1    Markowitz, J.F.2
  • 3
    • 27744461917 scopus 로고    scopus 로고
    • Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease
    • Gearry RB, Barclay ML. Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease. J Gastroenterol Hepatol 2005;20:1149-57.
    • (2005) J Gastroenterol Hepatol , vol.20 , pp. 1149-1157
    • Gearry, R.B.1    Barclay, M.L.2
  • 4
    • 33845895292 scopus 로고    scopus 로고
    • Insights in immunomo-dulatory therapies for ulcerative colitis and Crohn's disease
    • Nguyen GC, Harris ML, Dassopoulos T. Insights in immunomo-dulatory therapies for ulcerative colitis and Crohn's disease. Curr Gastroenterol Rep 2006;8:499-505.
    • (2006) Curr Gastroenterol Rep , vol.8 , pp. 499-505
    • Nguyen, G.C.1    Harris, M.L.2    Dassopoulos, T.3
  • 5
    • 35349027343 scopus 로고    scopus 로고
    • Lymphoma risk in inflammatory bowel disease: Is it the disease or its treatment?
    • Jones JL, Loftus EV Jr. Lymphoma risk in inflammatory bowel disease: is it the disease or its treatment? Inflamm Bowel Dis 2007;13:1299-307.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1299-1307
    • Jones, J.L.1    Loftus Jr., E.V.2
  • 6
    • 33845896308 scopus 로고    scopus 로고
    • Advances in biologic therapy for ulcerative colitis and Crohn's disease
    • D'Haens G, Daperno M. Advances in biologic therapy for ulcerative colitis and Crohn's disease. Curr Gastroenterol Rep 2006; 8:506-12.
    • (2006) Curr Gastroenterol Rep , vol.8 , pp. 506-512
    • D'Haens, G.1    Daperno, M.2
  • 7
    • 34547923651 scopus 로고    scopus 로고
    • Infliximab therapy in children and adolescents with inflammatory bowel disease
    • Veres G, Baldassano RN, Mamula P. Infliximab therapy in children and adolescents with inflammatory bowel disease. Drugs 2007; 67:1703-23.
    • (2007) Drugs , vol.67 , pp. 1703-1723
    • Veres, G.1    Baldassano, R.N.2    Mamula, P.3
  • 9
    • 33846592386 scopus 로고    scopus 로고
    • Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease
    • Mackey AC, Green L, Liang LC, et al. Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2007;44:265-7.
    • (2007) J Pediatr Gastroenterol Nutr , vol.44 , pp. 265-267
    • Mackey, A.C.1    Green, L.2    Liang, L.C.3
  • 10
    • 34347369156 scopus 로고    scopus 로고
    • Hepatosplenic T-cell lymphoma in adolescents and young adults with Crohn's disease: A cautionary tale?
    • Rosh JR, Gross T, Mamula P, et al. Hepatosplenic T-cell lymphoma in adolescents and young adults with Crohn's disease: a cautionary tale? Inflamm Bowel Dis 2007;13:1024-30.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1024-1030
    • Rosh, J.R.1    Gross, T.2    Mamula, P.3
  • 11
    • 34248346736 scopus 로고    scopus 로고
    • The non-Hodgkin lymphomas: A review of the epidemiologic literature
    • Alexander DD, Mink PJ, Adami HO, et al. The non-Hodgkin lymphomas: a review of the epidemiologic literature. Int J Cancer 2007;120 (Suppl 12):1-39.
    • (2007) Int J Cancer , vol.120 , Issue.SUPPL. 12 , pp. 1-39
    • Alexander, D.D.1    Mink, P.J.2    Adami, H.O.3
  • 12
    • 33646765444 scopus 로고    scopus 로고
    • Environmental factors and childhood acute leukemias and lymphomas
    • McNally RJ, Parker L. Environmental factors and childhood acute leukemias and lymphomas. Leuk Lymphoma 2006;47:583-98.
    • (2006) Leuk Lymphoma , vol.47 , pp. 583-598
    • McNally, R.J.1    Parker, L.2
  • 14
    • 1342287611 scopus 로고    scopus 로고
    • Editorial perspective - advances in B-cell non-Hodgkin's lymphoma
    • Hagenbeek A, Bischof Delaloye A. Editorial perspective - advances in B-cell non-Hodgkin's lymphoma. Leuk Lymphoma 2003;44 (Suppl 4):S1-4.
    • (2003) Leuk Lymphoma , vol.44 , Issue.SUPPL. 4
    • Hagenbeek, A.1    Bischof Delaloye, A.2
  • 15
    • 1642504716 scopus 로고    scopus 로고
    • An update of the epidemiology of non-Hodgkin's lymphoma
    • Chiu BC, Weisenburger DD. An update of the epidemiology of non-Hodgkin's lymphoma. Clin Lymphoma 2003;4:161-8.
    • (2003) Clin Lymphoma , vol.4 , pp. 161-168
    • Chiu, B.C.1    Weisenburger, D.D.2
  • 16
    • 4444226528 scopus 로고    scopus 로고
    • The epidemiology of non-Hodgkin's lymphoma
    • Fisher SG, Fisher RI. The epidemiology of non-Hodgkin's lymphoma. Oncogene 2004;23:6524-34.
    • (2004) Oncogene , vol.23 , pp. 6524-6534
    • Fisher, S.G.1    Fisher, R.I.2
  • 17
    • 0000192032 scopus 로고
    • Chronic ulcerative colitis associated with malignant disease
    • Bargen JA. Chronic ulcerative colitis associated with malignant disease. Arch Surg 1928;17:561-76.
    • (1928) Arch Surg , vol.17 , pp. 561-576
    • Bargen, J.A.1
  • 18
    • 0000042615 scopus 로고
    • Reticulum cell sarcoma: A case possibly originating in regional enteritis
    • Hughes RK. Reticulum cell sarcoma: a case possibly originating in regional enteritis. Ann Surg 1955;21:770-3.
    • (1955) Ann Surg , vol.21 , pp. 770-773
    • Hughes, R.K.1
  • 19
    • 24644495220 scopus 로고    scopus 로고
    • The risk of lymphoma in the treatment of inflammatory bowel disease with immunosuppressive agents
    • Kwon JH, Farrell RJ. The risk of lymphoma in the treatment of inflammatory bowel disease with immunosuppressive agents. Crit Rev Oncol/Hematol 2005;56:169-78.
    • (2005) Crit Rev Oncol/Hematol , vol.56 , pp. 169-178
    • Kwon, J.H.1    Farrell, R.J.2
  • 20
    • 33644892763 scopus 로고    scopus 로고
    • Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis
    • Baecklund E, Iliadou A, Askling J, et al. Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis. Arthritis Rheum 2006;54:692-701.
    • (2006) Arthritis Rheum , vol.54 , pp. 692-701
    • Baecklund, E.1    Iliadou, A.2    Askling, J.3
  • 21
    • 0034764110 scopus 로고    scopus 로고
    • Inflammatory bowel disease is not associated with an increased risk of lymphoma
    • Lewis JD, Bilker WB, Brensinger C, et al. Inflammatory bowel disease is not associated with an increased risk of lymphoma. Gastroenterology 2001;121:1080-7.
    • (2001) Gastroenterology , vol.121 , pp. 1080-1087
    • Lewis, J.D.1    Bilker, W.B.2    Brensinger, C.3
  • 22
    • 17644386242 scopus 로고    scopus 로고
    • Risk of haematopoietic cancer in patients with inflammatory bowel disease
    • Askling J, Brandt L, Lapidus A, et al. Risk of haematopoietic cancer in patients with inflammatory bowel disease. Gut 2005;54:617-22.
    • (2005) Gut , vol.54 , pp. 617-622
    • Askling, J.1    Brandt, L.2    Lapidus, A.3
  • 23
    • 0028135110 scopus 로고
    • Crohn's disease and cancer: A population-based cohort study
    • Persson PG, Karlén P, Bernell O, et al. Crohn's disease and cancer: a population-based cohort study. Gastroenterology 1994; 107:1675-9.
    • (1994) Gastroenterology , vol.107 , pp. 1675-1679
    • Persson, P.G.1    Karlén, P.2    Bernell, O.3
  • 24
    • 0033119199 scopus 로고    scopus 로고
    • Increased risk of cancer in ulcerative colitis: A population-based cohort study
    • Karlén P, Löfberg R, Broström O, et al. Increased risk of cancer in ulcerative colitis: a population-based cohort study. Am J Gastroenterol 1999;94:1047-52.
    • (1999) Am J Gastroenterol , vol.94 , pp. 1047-1052
    • Karlén, P.1    Löfberg, R.2    Broström, O.3
  • 25
    • 0033864288 scopus 로고    scopus 로고
    • Hodgkin's disease risk is increased in patients with ulcerative colitis
    • Palli D, Trallori G, Bagnoli S, et al. Hodgkin's disease risk is increased in patients with ulcerative colitis. Gastroenterology 2000;119:647-53.
    • (2000) Gastroenterology , vol.119 , pp. 647-653
    • Palli, D.1    Trallori, G.2    Bagnoli, S.3
  • 26
    • 0022410723 scopus 로고
    • Extraintestinal cancers in inflammatory bowel disease
    • Greenstein AJ, Gennuso R, Sachar DB, et al. Extraintestinal cancers in inflammatory bowel disease. Cancer 1985;56:2914-21.
    • (1985) Cancer , vol.56 , pp. 2914-2921
    • Greenstein, A.J.1    Gennuso, R.2    Sachar, D.B.3
  • 27
    • 0026100447 scopus 로고
    • Extracolonic malignancies in inflammatory bowel disease
    • Ekbom A, Helmick C, Zack M, et al. Extracolonic malignancies in inflammatory bowel disease. Cancer 1991;67:2015-9.
    • (1991) Cancer , vol.67 , pp. 2015-2019
    • Ekbom, A.1    Helmick, C.2    Zack, M.3
  • 29
    • 0028135110 scopus 로고
    • Crohn's disease and cancer: A population-based cohort study
    • Persson PG, Karlén P, Bernell O, et al. Crohn's disease and cancer: a population-based cohort study. Gastroenterology 1994; 107:1675-9.
    • (1994) Gastroenterology , vol.107 , pp. 1675-1679
    • Persson, P.G.1    Karlén, P.2    Bernell, O.3
  • 30
    • 0034913946 scopus 로고    scopus 로고
    • Review article: The risk of lymphoma associated with inflammatory bowel disease and immunosuppres-sive treatment
    • Aithal GP, Mansfield JC. Review article: the risk of lymphoma associated with inflammatory bowel disease and immunosuppres-sive treatment. Aliment Pharmacol Ther 2001;15:1101-8.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1101-1108
    • Aithal, G.P.1    Mansfield, J.C.2
  • 31
    • 33847000579 scopus 로고    scopus 로고
    • Apoptosis of T cells and the control of inflammatory bowel disease: Therapeutic implications
    • Mudter J, Neurath MF. Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications. Gut 2007; 56:293-303.
    • (2007) Gut , vol.56 , pp. 293-303
    • Mudter, J.1    Neurath, M.F.2
  • 32
    • 34250877764 scopus 로고    scopus 로고
    • Diagnosis and management of inflammatory bowel disease in children
    • Carvalho R, Hyams JS. Diagnosis and management of inflammatory bowel disease in children. Semin Pediatr Surg 2007; 16:164-71.
    • (2007) Semin Pediatr Surg , vol.16 , pp. 164-171
    • Carvalho, R.1    Hyams, J.S.2
  • 33
    • 22644446331 scopus 로고    scopus 로고
    • Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine
    • Kandiel A, Fraser AG, Korelitz BI, et al. Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. Gut 2005;54:1121-5.
    • (2005) Gut , vol.54 , pp. 1121-1125
    • Kandiel, A.1    Fraser, A.G.2    Korelitz, B.I.3
  • 34
    • 0033795223 scopus 로고    scopus 로고
    • Increased incidence of non-Hodgkin's lymphoma in inflammatory bowel disease patients on immunosuppressive therapy but overall risk is low
    • Farrell RJ, Ang Y, Kileen P, et al. Increased incidence of non-Hodgkin's lymphoma in inflammatory bowel disease patients on immunosuppressive therapy but overall risk is low. Gut 2000; 47:514-9.
    • (2000) Gut , vol.47 , pp. 514-519
    • Farrell, R.J.1    Ang, Y.2    Kileen, P.3
  • 35
    • 33750519460 scopus 로고    scopus 로고
    • Efficacy of methotrexate in pediatric Crohn's disease - a French multicenter study
    • Uhlen S, Belbouab R, Narebski K, et al. Efficacy of methotrexate in pediatric Crohn's disease - a French multicenter study. Inflamm Bowel Dis 2006;12:1053-7.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 1053-1057
    • Uhlen, S.1    Belbouab, R.2    Narebski, K.3
  • 36
    • 36549026839 scopus 로고    scopus 로고
    • Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's disease
    • Turner D, Grossman AB, Rosh J, et al. Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's disease. Am J Gastroenterol 2007;102:2804-12.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2804-2812
    • Turner, D.1    Grossman, A.B.2    Rosh, J.3
  • 38
    • 34248547187 scopus 로고    scopus 로고
    • The effect of methotrexate and anti-tumor necrosis factor therapy on the risk of lymphoma in rheumatoid arthritis in 19,562 patients during 89,710 person-years of observation
    • Wolfe F, Michaud K. The effect of methotrexate and anti-tumor necrosis factor therapy on the risk of lymphoma in rheumatoid arthritis in 19,562 patients during 89,710 person-years of observation. Arthritis Rheum 2007;56:1433-9.
    • (2007) Arthritis Rheum , vol.56 , pp. 1433-1439
    • Wolfe, F.1    Michaud, K.2
  • 40
    • 0037345583 scopus 로고    scopus 로고
    • Immunomodulators and "on demand" therapy with infliximab in Crohn's disease: Clinical experience with 400 infusions
    • Kinney T, Rawlins M, Kozarek R, et al. Immunomodulators and "on demand" therapy with infliximab in Crohn's disease: clinical experience with 400 infusions. Am J Gastroenterol 2003; 98:608-12.
    • (2003) Am J Gastroenterol , vol.98 , pp. 608-612
    • Kinney, T.1    Rawlins, M.2    Kozarek, R.3
  • 41
    • 0347991877 scopus 로고    scopus 로고
    • The safety profile of infliximab in patients with Crohn's disease: The Mayo clinic experience in 500 patients
    • Colombel JF, Loftus EV Jr, Tremaine WJ, et al. The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patients. Gastroenterology 2004; 126:19-31.
    • (2004) Gastroenterology , vol.126 , pp. 19-31
    • Colombel, J.F.1    Loftus Jr, E.V.2    Tremaine, W.J.3
  • 42
    • 2442696315 scopus 로고    scopus 로고
    • Infliximab in inflammatory bowel disease: Clinical outcome in a population based cohort from Stockholm County
    • Ljung T, Karlén P, Schmidt D, et al. Infliximab in inflammatory bowel disease: clinical outcome in a population based cohort from Stockholm County. Gut 2004;53:849-53.
    • (2004) Gut , vol.53 , pp. 849-853
    • Ljung, T.1    Karlén, P.2    Schmidt, D.3
  • 43
    • 30944442404 scopus 로고    scopus 로고
    • Infliximab and newly diagnosed neoplasia in Crohn's disease: A multicentre matched pair study
    • Biancone L, Orlando A, Kohn A, et al. Infliximab and newly diagnosed neoplasia in Crohn's disease: a multicentre matched pair study. Gut 2006;55:228-33.
    • (2006) Gut , vol.55 , pp. 228-233
    • Biancone, L.1    Orlando, A.2    Kohn, A.3
  • 44
    • 33845384834 scopus 로고    scopus 로고
    • Review article: Altering the natural history of Crohn's disease - evidence for and against current therapies
    • Vermeire S, van Assche G, Rutgeerts P. Review article: altering the natural history of Crohn's disease - evidence for and against current therapies. Aliment Pharmacol Ther 2007;25:3-12.
    • (2007) Aliment Pharmacol Ther , vol.25 , pp. 3-12
    • Vermeire, S.1    van Assche, G.2    Rutgeerts, P.3
  • 45
    • 34347383383 scopus 로고    scopus 로고
    • Safety of infliximab and other Crohn's disease therapies - Treat™ Registry data with nearly 20,000 patient-years and follow-up
    • Lichtenstein GR, Cohen RD, Feagan BG, et al. Safety of infliximab and other Crohn's disease therapies - Treat™ Registry data with nearly 20,000 patient-years and follow-up. Gastroenterology 2007;132:A178.
    • (2007) Gastroenterology , vol.132
    • Lichtenstein, G.R.1    Cohen, R.D.2    Feagan, B.G.3
  • 46
    • 33746345358 scopus 로고    scopus 로고
    • Risks and benefits of infliximab for the treatment of Crohn's disease
    • Siegel CA, Hur C, Korzenik JR, et al. Risks and benefits of infliximab for the treatment of Crohn's disease. Clin Gastroenterol Hepatol 2006;4:1017-24.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 1017-1024
    • Siegel, C.A.1    Hur, C.2    Korzenik, J.R.3
  • 47
    • 33845583291 scopus 로고    scopus 로고
    • Lymphoma rheumatoid arthritis - again
    • Symmons DP. Lymphoma rheumatoid arthritis - again. Rheumatology (Oxford) 2007;46:1-2.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 1-2
    • Symmons, D.P.1
  • 48
    • 17644374819 scopus 로고    scopus 로고
    • Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas
    • Geborek P, Bladstrom A, Turesson C, et al. Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas. Ann Rheum Dis 2005;64:699-703.
    • (2005) Ann Rheum Dis , vol.64 , pp. 699-703
    • Geborek, P.1    Bladstrom, A.2    Turesson, C.3
  • 49
    • 33646696885 scopus 로고    scopus 로고
    • Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
    • Bongartz T, Sutton AJ, Sweeting MJ, et al. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA 2006; 295:2275-85.
    • (2006) JAMA , vol.295 , pp. 2275-2285
    • Bongartz, T.1    Sutton, A.J.2    Sweeting, M.J.3
  • 50
    • 0019515716 scopus 로고
    • Erythrophagocytic Tγ lymphoma: A clinicopathologic entity resembling malignant histiocytosis
    • Kadin M, Kamoun M, Lamberg J. Erythrophagocytic Tγ lymphoma: a clinicopathologic entity resembling malignant histiocytosis. N Engl J Med 1981;304:648-53.
    • (1981) N Engl J Med , vol.304 , pp. 648-653
    • Kadin, M.1    Kamoun, M.2    Lamberg, J.3
  • 51
    • 0345599964 scopus 로고    scopus 로고
    • Hepatosplenic γδT-cell lymphoma is a rare clinicopathologic entity with poor outcome: Report on a series of 21 patients
    • Belhadj K, Reyes F, Farcewt J-P, et al. Hepatosplenic γδT-cell lymphoma is a rare clinicopathologic entity with poor outcome: report on a series of 21 patients. Blood 2003;102:4261-9.
    • (2003) Blood , vol.102 , pp. 4261-4269
    • Belhadj, K.1    Reyes, F.2    Farcewt, J.-P.3
  • 53
    • 0025181012 scopus 로고
    • Expression of the alpha/ beta and gamma/delta T-cell receptors in 57 cases of peripheral T-cell lymphomas: Identification of a subset of γδT-cell lymphomas
    • Gaulard P, Bourquelot P, Kanavaros P, et al. Expression of the alpha/ beta and gamma/delta T-cell receptors in 57 cases of peripheral T-cell lymphomas: identification of a subset of γδT-cell lymphomas. Am J Pathol 1990;137:617-28.
    • (1990) Am J Pathol , vol.137 , pp. 617-628
    • Gaulard, P.1    Bourquelot, P.2    Kanavaros, P.3
  • 54
    • 67650841052 scopus 로고    scopus 로고
    • Percy C, Smith M, Linet M, et al. Lymphomas and reticuloen-dothelial neoplasms. In: Ries LA, Smith MA, Gurney JG, et al (editors). Cancer Incidence and Survival Among Children and Adolescents: United States SEER Program 1975-1995. Bethesda, MD: National Cancer Institute, SEER Program. NIH Pub. No. 99- 4649; 1999:35-50.
    • Percy C, Smith M, Linet M, et al. Lymphomas and reticuloen-dothelial neoplasms. In: Ries LA, Smith MA, Gurney JG, et al (editors). Cancer Incidence and Survival Among Children and Adolescents: United States SEER Program 1975-1995. Bethesda, MD: National Cancer Institute, SEER Program. NIH Pub. No. 99- 4649; 1999:35-50.
  • 55
    • 4344645179 scopus 로고    scopus 로고
    • Post transplant T-cell lymphoma: A case series of four patients from a single unit and review of the literature
    • Rajakariar R, Bhattacharyya M, Norton A, et al. Post transplant T-cell lymphoma: a case series of four patients from a single unit and review of the literature. Am J Transplant 2004;4:1534-8.
    • (2004) Am J Transplant , vol.4 , pp. 1534-1538
    • Rajakariar, R.1    Bhattacharyya, M.2    Norton, A.3
  • 56
    • 18144453452 scopus 로고    scopus 로고
    • Hepato-splenic gamma-delta T-cell lymphoma as a late onset posttransplant lymphoproliferative disorder in renal transplant recipients
    • Wu H, Wasik MA, Przbylski G, et al. Hepato-splenic gamma-delta T-cell lymphoma as a late onset posttransplant lymphoproliferative disorder in renal transplant recipients. Am J Clin Pathol 2000; 113:487-96.
    • (2000) Am J Clin Pathol , vol.113 , pp. 487-496
    • Wu, H.1    Wasik, M.A.2    Przbylski, G.3
  • 57
    • 0000112159 scopus 로고    scopus 로고
    • Intravenous cyclosporine for refractory attacks of Crohn's disease (CD): Long-term follow-up of patients [abstract]
    • Lemann M, de La Valussiere G, Bouhnik Y, et al. Intravenous cyclosporine for refractory attacks of Crohn's disease (CD): long-term follow-up of patients [abstract]. Gastroenterology 1998; 114:A1020.
    • (1998) Gastroenterology , vol.114
    • Lemann, M.1    de La Valussiere, G.2    Bouhnik, Y.3
  • 58
    • 0037344897 scopus 로고    scopus 로고
    • Hepatosplenic T-gamma delta lymphoma in a patient with Crohn's disease treated with azathioprine
    • Navarro JT, Ribera JM, Mate JL, et al. Hepatosplenic T-gamma delta lymphoma in a patient with Crohn's disease treated with azathioprine. Leuk Lymphoma 2003;44:531-3.
    • (2003) Leuk Lymphoma , vol.44 , pp. 531-533
    • Navarro, J.T.1    Ribera, J.M.2    Mate, J.L.3
  • 59
    • 33646495278 scopus 로고    scopus 로고
    • A case of hepatosplenic gamma-delta T-cell lymphoma with a transient response to fludarabine and alemtuzumab
    • Mittal S, Milner BJ, Johnston PW, et al. A case of hepatosplenic gamma-delta T-cell lymphoma with a transient response to fludarabine and alemtuzumab. Eur J Haematol 2006;76:531-4.
    • (2006) Eur J Haematol , vol.76 , pp. 531-534
    • Mittal, S.1    Milner, B.J.2    Johnston, P.W.3
  • 60
    • 56549097517 scopus 로고    scopus 로고
    • Hepatosplenic T-cell-lymphoma in a 15-year-old boy with ulcerative colitis treated with azathioprine for 9 years
    • Keller KM, Magdefrau C, Bohl L, et al. Hepatosplenic T-cell-lymphoma in a 15-year-old boy with ulcerative colitis treated with azathioprine for 9 years. J Pediatr Gastroenterol Nutr 2007; 44:e259.
    • (2007) J Pediatr Gastroenterol Nutr , vol.44
    • Keller, K.M.1    Magdefrau, C.2    Bohl, L.3
  • 61
    • 34250877764 scopus 로고    scopus 로고
    • Diagnosis and management of inflammatory bowel disease in children
    • Carvalho R, Hyams JS. Diagnosis and management of inflammatory bowel disease in children. Semin Pediatr Surg 2007;16:164-71.
    • (2007) Semin Pediatr Surg , vol.16 , pp. 164-171
    • Carvalho, R.1    Hyams, J.S.2
  • 62
    • 33748147712 scopus 로고    scopus 로고
    • acute and 1-year outcomes in newly diagnosed children with Crohn's disease
    • Pediatric IBD Collaborative Research GroupCorticosteroid therapy in the age of infliximab
    • Markowitz J, Hyams J, Mack D, et al., Pediatric IBD Collaborative Research GroupCorticosteroid therapy in the age of infliximab: acute and 1-year outcomes in newly diagnosed children with Crohn's disease. Clin Gastroenterol Hepatol 2006;4:1124-9.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 1124-1129
    • Markowitz, J.1    Hyams, J.2    Mack, D.3
  • 63
    • 33748210698 scopus 로고    scopus 로고
    • Inflammatory Bowel Disease Collaborative Research GroupThe natural history of corticosteroid therapy for ulcerative colitis in children
    • Hyams J, Markowitz J, Lerer T, et al., Inflammatory Bowel Disease Collaborative Research GroupThe natural history of corticosteroid therapy for ulcerative colitis in children. Clin Gastroenterol Hepatol 2006;4:1118-23.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 1118-1123
    • Hyams, J.1    Markowitz, J.2    Lerer, T.3
  • 64
    • 36749081017 scopus 로고    scopus 로고
    • Pediatric inflammatory bowel disease: Clinical and molecular genetics
    • Biank V, Broeckel U, Kugathasan S. Pediatric inflammatory bowel disease: clinical and molecular genetics. Inflamm Bowel Dis 2007;13:1430-8.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1430-1438
    • Biank, V.1    Broeckel, U.2    Kugathasan, S.3
  • 65
    • 33644892470 scopus 로고    scopus 로고
    • Review article: Infliximab therapy for inflammatory bowel disease - seven years on
    • Rutgeerts P, Van Assche G, Vermeire S. Review article: infliximab therapy for inflammatory bowel disease - seven years on. Aliment Pharmacol Ther 2006;23:451-63.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 451-463
    • Rutgeerts, P.1    Van Assche, G.2    Vermeire, S.3
  • 66
    • 33947397636 scopus 로고    scopus 로고
    • REACH Study Group-Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children
    • Hyams J, Crandall W, Kugathasan S, et al., REACH Study Group-Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children. Gastroenterology 2007;132:863-73.
    • (2007) Gastroenterology , vol.132 , pp. 863-873
    • Hyams, J.1    Crandall, W.2    Kugathasan, S.3
  • 67
    • 34447102570 scopus 로고    scopus 로고
    • Clark M, Colombel JF, Feagan BC, et al. American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006. Gastroenterology 2007;133:312-39.
    • Clark M, Colombel JF, Feagan BC, et al. American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006. Gastroenterology 2007;133:312-39.
  • 68
    • 33847606974 scopus 로고    scopus 로고
    • Biologic therapy in Crohn's disease: Review of the evidence
    • Loftus EV Jr. Biologic therapy in Crohn's disease: review of the evidence. Rev Gastroenterol Disord 2007;7 (Suppl 1):S3-12.
    • (2007) Rev Gastroenterol Disord , vol.7 , Issue.SUPPL. 1
    • Loftus Jr., E.V.1
  • 69
    • 34547923651 scopus 로고    scopus 로고
    • Infliximab therapy in children and adolescents with inflammatory bowel disease
    • Veres G, Baldassano RN, Mamula P. Infliximab therapy in children and adolescents with inflammatory bowel disease. Drugs 2007; 67:1703-23.
    • (2007) Drugs , vol.67 , pp. 1703-1723
    • Veres, G.1    Baldassano, R.N.2    Mamula, P.3
  • 70
    • 67650812015 scopus 로고    scopus 로고
    • Immunosuppressive therapy in the formation of antibodies to infliximab in Crohn's disease
    • Hanauer SB. Immunosuppressive therapy in the formation of antibodies to infliximab in Crohn's disease. Curr Gastroenterol Rep 2007;9:487-8.
    • (2007) Curr Gastroenterol Rep , vol.9 , pp. 487-488
    • Hanauer, S.B.1
  • 71
    • 34548130215 scopus 로고    scopus 로고
    • Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease
    • Vermeire S, Noman M, Van Assche G, et al. Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease. Gut 2007;56:1226-31.
    • (2007) Gut , vol.56 , pp. 1226-1231
    • Vermeire, S.1    Noman, M.2    Van Assche, G.3
  • 72
    • 34248136340 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Clinical aspects and established and evolving therapies
    • Baumgart DC, Sandborn WJ. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 2007; 369:1641-57.
    • (2007) Lancet , vol.369 , pp. 1641-1657
    • Baumgart, D.C.1    Sandborn, W.J.2
  • 73
    • 44649090092 scopus 로고    scopus 로고
    • Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: A randomized trial
    • Van Assche G, Magdelaine-Beuzelin C, D'Haens G, et al. Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial. Gastroenterology 2008;134:1861-8.
    • (2008) Gastroenterology , vol.134 , pp. 1861-1868
    • Van Assche, G.1    Magdelaine-Beuzelin, C.2    D'Haens, G.3
  • 74
    • 34848840814 scopus 로고    scopus 로고
    • Infliximab adminis-teredas3-doseinduction followedbyscheduled maintenance therapy in IBD: Comparable clinical outcomes with or without concomitant immunomodulators [abstract]
    • Lichtenstein GR, Diamond RH, Wagner C, et al. Infliximab adminis-teredas3-doseinduction followedbyscheduled maintenance therapy in IBD: comparable clinical outcomes with or without concomitant immunomodulators [abstract]. Gastroenterology 2007;132:A146.
    • (2007) Gastroenterology , vol.132
    • Lichtenstein, G.R.1    Diamond, R.H.2    Wagner, C.3
  • 75
    • 28844473957 scopus 로고    scopus 로고
    • Infliximab for induction and maintenance therapy for ulcerative colitis
    • Rutgeerts P, Sandborn WJ, Feagan BG, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005;353:2462-76.
    • (2005) N Engl J Med , vol.353 , pp. 2462-2476
    • Rutgeerts, P.1    Sandborn, W.J.2    Feagan, B.G.3
  • 76
    • 0037018761 scopus 로고    scopus 로고
    • ACCENT I Study GroupMaintenance infliximab for Crohn's disease: The ACCENT I randomised trial
    • Hanauer SB, Feagan BG, Lichtenstein GR, et al., ACCENT I Study GroupMaintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 2002;359:1541-9.
    • (2002) Lancet , vol.359 , pp. 1541-1549
    • Hanauer, S.B.1    Feagan, B.G.2    Lichtenstein, G.R.3
  • 77
    • 33644873228 scopus 로고    scopus 로고
    • American College of Physicians; American Physiological SocietyNew concepts in the pathophysiology of inflammatory bowel disease
    • Bamias G, Nyce MR, De La Rue SA, et al., American College of Physicians; American Physiological SocietyNew concepts in the pathophysiology of inflammatory bowel disease. Ann Intern Med 2005;143:895-904.
    • (2005) Ann Intern Med , vol.143 , pp. 895-904
    • Bamias, G.1    Nyce, M.R.2    De La Rue, S.A.3
  • 78
    • 33846242958 scopus 로고    scopus 로고
    • Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
    • Colombel JF, Sandborn WJ, Rutgeerts P, et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology 2007; 132:52-65.
    • (2007) Gastroenterology , vol.132 , pp. 52-65
    • Colombel, J.F.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 79
    • 34447523749 scopus 로고    scopus 로고
    • PRECISE 1 Study InvestigatorsCertolizumab pegol for the treatment of Crohn's disease
    • Sandborn WJ, Feagan BG, Stoinov S, et al., PRECISE 1 Study InvestigatorsCertolizumab pegol for the treatment of Crohn's disease. N Engl J Med 2007;357:228-38.
    • (2007) N Engl J Med , vol.357 , pp. 228-238
    • Sandborn, W.J.1    Feagan, B.G.2    Stoinov, S.3
  • 80
    • 0033913792 scopus 로고    scopus 로고
    • Nutrition as primary therapy in pediatric Crohn's disease: Fact or fantasy?
    • Ruemmele FM, Roy CC, Levy E, Seidman EG. Nutrition as primary therapy in pediatric Crohn's disease: Fact or fantasy? J Pediatr 2000;136:285-91.
    • (2000) J Pediatr , vol.136 , pp. 285-291
    • Ruemmele, F.M.1    Roy, C.C.2    Levy, E.3    Seidman, E.G.4
  • 81
    • 33744778418 scopus 로고    scopus 로고
    • Borrelli O, Cordischi L, Cirulli M, et al. Polymeric diet alone versus corticosteroids in the treatment of active pediatric Crohn's disease: a randomized controlled open-label trial. Clin Gastroenterol Hepatol 2006;4:744-53.
    • Borrelli O, Cordischi L, Cirulli M, et al. Polymeric diet alone versus corticosteroids in the treatment of active pediatric Crohn's disease: a randomized controlled open-label trial. Clin Gastroenterol Hepatol 2006;4:744-53.
  • 82
    • 38149017695 scopus 로고    scopus 로고
    • Systematic review: Nutritional therapy in paediatric Crohn's disease
    • Day AS, Whitten KE, Sidler M, et al. Systematic review: nutritional therapy in paediatric Crohn's disease. Aliment Pharmacol Ther 2008;27:293-307.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 293-307
    • Day, A.S.1    Whitten, K.E.2    Sidler, M.3


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