Prophylaxis of experimentally induced calcium oxalate nephrolithiasis in rats by Zhulingtang, a traditional Chinese herbal formula

Urologia Internationalis

Volumn 82, Issue 4, 2009, Pages 464-471

  Tsai, Chou Huang ^a   Pan, Tien Chien ^a,e   Lai, Ming Tsong ^d   Lee, Shih Chang ^b   Chen, Ming Lun ^b   Jheng, Jhih Ren ^b   Chen, Wen Chi ^b,c,f  

^a Graduate Institute of Chinese Medical Science   (Taiwan)

^b Department of Chinese Medicine ^*  (Taiwan)

^c Pediatric Dentistry   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Calcium oxalate; Ethylene glycol; Traditional Chinese medicine; Zhulingtang

Indexed keywords

CALCIUM OXALATE; CHINESE DRUG; ETHYLENE GLYCOL; PHOSPHATE; STARCH; UNCLASSIFIED DRUG; ZHULINGTANG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; GROWTH RETARDATION; HISTOPATHOLOGY; LOW DRUG DOSE; MALE; MICROSCOPY; NEPHROLITHIASIS; NONHUMAN; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL; PROPHYLAXIS; RAT; SCORING SYSTEM; TREATMENT RESPONSE; URINALYSIS;

ANIMALS; CALCIUM OXALATE; DRUGS, CHINESE HERBAL; MALE; NEPHROLITHIASIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 67650333641     PISSN: 00421138     EISSN: None     Source Type: Journal    
DOI: 10.1159/000218539     Document Type: Article

References (27)

1. Yasui T, Fujita K, Sato M, Sugimoto M, Iguchi M, Nomura S, Kohri K: The effect of takusha, a kampo medicine, on renal stone formation and osteopontin expression in a rat urolithiasis model. Urol Res 1999;27:194-199.
2. Suzuki K, Kawamura K, Tsugawa R: Formation and growth inhibition of calcium oxalate crystals by takusha (alismatis rhizoma). Scan Microsc 1999;13:183-189.
3. Liu Q, Sato S, Kishikawa T, Matsuzaki H, Yamanaka N: Effectiveness of a traditional Chinese medicine, Wulingsan, in suppressing the development of nephrocalcinosis induced by a high phosphorus diet in young rats. Med Electron Microsc 2001;34:103-114.
4. Yoshimura K, Miyake O, Okuyama A, Yoshioka T, Honda M, Yamaguchi S, Koide T: Effect of chorei-to and gorei-san on calcium oxalate crystallization in human urine. Hinyokika Kiyo 1998;44:13-16.
5. Chen YC, Ho CY, Chen LD, Hsu SF, Chen WC: Wu-Ling-San formula inhibits the crystallization of calcium oxalate in vitro. Am J Chin Med 2007;35:533-541.
6. Tsai CH, Chen YC, Chen LD, Pan TC, Ho CY, Lai MT, Tsai FJ, Chen WC: A traditional Chinese herbal antilithic formula, Wulingsan, effectively prevents the renal deposition of calcium oxalate crystal in ethylene glycol-fed rats. Urol Res 2008;36:17-24.
7. Atmani F, Khan SR: Effects of an extract from Herniaria hirsutaon calcium oxalate crystallization in vitro. BJU Int 2000;85: 621-625.
8. Freitas A, Schor N, Boim M: The effect of Phyllanthus niruri on urinary inhibitors of calcium oxalate crystallization and other factors associated with renal stone formation. BJU Int 2002; 89:829-834.
9. Das I, Gupta S, Ansari S, Pandey V, Rastogi R: In vitro inhibition and dissolution of calcium oxalate by edible plant Trianthema monogyna and pulse Macrotyloma uniflorum ex tracts. J Cr ysta l Growth 2005;273:546-554.
10. Bensky D, Barolet R: Chinese Herbal Medicine: Formulas and Strategies. Seattle, East-land, 1990.
11. Lee Y, Huang W, Chiang H: Determinant role of testosterone in the pathogenesis of urolithiasis in rats. J Urol 1992;147:1134-1138.
12. Nelde H, Bichler K, Strohmaier W: Nephrocalcinosis in the kidney of the rat on atherogenic diet and the effect of calcium antagonists (nifedipine); in Bichler K, Strohmaier W (eds): Nephrocalcinosis Calcium Antagonists and Kidney. Berlin, Springer, 1988, pp 113-125.
13. Lee Y, Chang L, Chen M: Characterization of ethylene glycol induced urolithiasis model in rats. J Urol ROC 1991;2:518-524.
14. Wang JH, Wang SY, Shi TL, Zhang CR, Xu H, Lai Z, Geng XY: Study on the mechanism of Zhuling decoction on refraining the formation of calculus of kidney. Hunan Guiding J TCM 2004;10:80-82.
15. Koide T, Yamaguchi S, Utsunomiya M, Yoshioka T, Sugiyama K: The inhibitory effect of kampou extracts on in vitro calcium oxalate crystallization and in vivo stone formation inananimal model. Int J Urol 1995;2:81-86.
16. Wang S, Deng C, Shi Z: Influence of rhizome alismatis on inhibition of renal stone formation. J Guangzhou Univ Tradit Chin Med 2003; 20: 294-296.
17. Zhou X, Yin R, Ruan H, Zhang Y, Pi H, Zhao X, Wu J: Analysis of active ingredients in Alisma orientalis (Sam.) Juze extract for inhibiting formation of urinary oxalate calcium calculi by 2D NMR. Chin J Magn Reson 2005;22:196-200.
18. Cao Z, Liu J, Zhou S: Effect of Alisma orientalis extract on renal stone formation and the expression of inter-alpha-trypsin inhibitor in rat urolithiasis model. Chin J Exp Surg 2004;21:295-297.
19. Yin C, Liu J, Zhang Y: Effects of Alisma orientalis Juzep on calcium oxalate crystallization in vitro and calcium oxalate renal stone in rats. Acta Univ Med Tongji 1997;26:99-101.
20. Hennequin C, Tardivel S, Medetognon J, Drueke T, Daudon M, Lacour B: A stable animal model of diet-induced calcium oxalate crystalluria. Urol Res 1998;26:57-63.
21. Lee Y, Tsai J, Huang J: Combined use of 30% lactose rich diet and 1% ethylene glycol: a new animal model for the study of urolithiasis. J Urol ROC 2000;11:149-154.
22. Khan S, Glenton P, Byer K: Modeling of hyperoxaluric calcium oxalate nephrolithiasis: experimental induction of hyperoxaluria by hydroxy- L -proline. Kidney Int 2006;70:914-923.
23. Marengo S, Chen DH, MacLennan G, Res-nick M, Jacobs G: Minipump induced hyperoxaluria and crystal deposition in rats: a model for calcium oxalate urolithiasis. J Urol 2004;171:1304-1308.
24. Connor R, Worcester E, Evan A, Meehan S, Kuznetsov D, Laven B, Sommer A, Bledsoe SB, Parks J, Coe F, Grynpas M, Gerber G: Nephrolithiasis and nephrocalcinosis in rats with small bowel resection. Urol Res 2005; 33:105-115.
25. Khan S, Finlayson B, Hackett R: Experimental calcium oxalate nephrolithiasis in the rat. Role of renal papilla. Am J Pathol 1982;107: 59-69.
26. Tawashi R, Cousineau M, Sharkawi M: Calcium oxalate crystal formation in the kidneys of rats injected with 4-hydroxy-L-proline. Urol Res 1980;8:121-127.
27. Green M, Hatch M, Freel R: Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. Am J Physiol Renal Physiol 2005;289:F536-F543.