Could the treatment of differentiated thyroid carcinoma with 3.7 and 5.55 GBq of ( 131I)NaI, on an outpatient basis, be safe?

Nuclear Medicine Communications

Volumn 30, Issue 7, 2009, Pages 533-541

  Carvalho, José Willegaignon De Amorim De ^a,b   Sapienza, Marcelo ^a,b   Ono, Carla ^a,b   Watanabe, Tomoco ^a,b   Guimarães, Maria Inês ^a,b   Gutterres, Ricardo ^c   Marechal, Maria Helena ^c   Buchpiguel, Carlos ^a,b  

^a Department of Radiology   (Bangladesh)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES   (Brazil)

Author keywords

131I therapy; Dosimetry; Outpatient treatment; Radiation protection; Radiological impact; Thyroid cancer

Indexed keywords

ANTIEMETIC AGENT; METOCLOPRAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; RADIOACTIVE IODINE; SODIUM IODIDE I 131;

ADULT; AGITATION; AKATHISIA; ANALYSIS; ANOREXIA; ARTICLE; ASTHENIA; CANCER THERAPY; CAREGIVER; CLINICAL ARTICLE; CONTAMINATION; ENVIRONMENT; ENVIRONMENTAL EXPOSURE; EVALUATION; FEMALE; HEALTH PRACTITIONER; HOUSEHOLD; HUMAN; MALE; MEASUREMENT; METHODOLOGY; MONITORING; NAUSEA; OUTPATIENT; PAROTID GLAND DISEASE; PAROTID GLAND EDEMA; PAROTID GLAND PAIN; PRACTICE GUIDELINE; RADIATION DOSE; RADIATION PROTECTION; RADIATION SAFETY; RADIOLOGY; RELATIVE; SALIVARY GLAND DISEASE; SALIVARY GLAND EDEMA; SALIVARY GLAND PAIN; SIDE EFFECT; SOLID WASTE; THERMOLUMINESCENCE DOSIMETER; THYROID CARCINOMA; VOMITING; WHOLE BODY RADIATION;

ADULT; AMBULATORY CARE; CAREGIVERS; FAMILY; FEMALE; HOUSING; HUMANS; IODINE RADIOISOTOPES; MALE; MIDDLE AGED; RADIATION DOSAGE; RADIATION PROTECTION; RADIOTHERAPY DOSAGE; SAFETY; SODIUM IODIDE; THYROID NEOPLASMS; TIME FACTORS; WHOLE-BODY IRRADIATION;

EID: 67650326973     PISSN: 01433636     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNM.0b013e32832b79bc     Document Type: Article

References (39)

1. Mazzaferri EL, Kloos RT. Clinical review 128: current approaches to primary therapy for papillary and follicular thyroid cancer. J Clin Endocrinol Metab 2000; 86:1447-1463.
2. ICRP. Release of patients after therapy with unsealed radionuclides. Publication 94.
3. Lubin E. Definitive improvement in the approach to the treated patient as a radioactive source. J Nucl Med 2002; 43:364-365.
4. 131I therapy: inpatient or outpatient? J Nucl Med 2000; 41:1876-1878.
5. 131I clearance in thyroid cancer therapy. Health Phys 2006; 91:123-127.
6. CNEN. Gerência de rejeitos radioativos em instalaçōes radiativas. Norma 6.05.
7. 131I- Tositumomab therapy. J Nucl Med 2002; 43:354-363.
8. IAEA. Radiological protection for medical exposure to ionizing radiation. Safety Guide n. RS-G-1.5.
9. IAEA. International basic safety standards for protection against ionizing radiation and for the safety of radiation sources. Safety Series n. 115 (BSS-115).
10. ICRP. Recommendations of the International Commission on Radiological Protection. Publication 60.
11. ICRP. Radiological protection and safety in medicine. Publication 73.
12. CNEN. Diretrizes básicas de proteç;āo radiológica. Norma 3.01.
13. 131I) treatment of hyperthyroidism: radiation protection and quality assurance. Eur J Nucl Med 1999; 26:683-685.
14. 131I-anti-B1 antibody: radiation exposure to family members. J Nucl Med 2001; 42:907-915.
15. Cappelen T, Unhjem JF, Amundsen AL, Kravdal G, Folling I. Radiation exposure to family members of patients with thyrotoxicosis treated with iodine-131. Eur J Nucl Med Mol Imaging 2006; 33:81-86.
16. 131I) therapy for thyroid carcinoma. JAMA 2000; 283:2272-2274.
17. 131I. Radiat Prot Dosim 2006; 118:22-27.
18. IAEA. Application of the concepts of exclusion, exemption and clearance. Safety Guide n. RS-G-1.7.
19. IAEA Release of sites from regulatory control on termination of practices. Safety Guide n. WS-G-5.1.
20. IAEA. Clearance levels for radionuclides in solid materials: application exemption principles. IAEA-TECDOC-855.
21. IAEA. Radiological aspects of non-fixed contamination of packages and conveyances. IAEA-TECDOC-1449.
22. UNSCEAR. Sources and effects of ionizing radiation. UNSCEAR 2000.
23. Martin JE, Fenner FD. Radioactvitty in municipal sewage and sludge. Public Health Rep 1997; 112:308-316.
24. Prichard HM, Gesell TF, Davis E. Iodine-131 levels in sludge and treated municipal wastewaters near a large medical complex. Am J Public Health 1981; 71:47-52.
25. Larsen IL, Stetar EA, Giles BG, Garrison B. Concentration of iodine-131 released from a hospital into a municipal sewer. RSO Magazine 2001; 6:13-18.
26. 131I) iodobenzylguanidine (MIBG) in municipal sewerage. Health Phys 1997; 73:333-339.
27. Washington State Department of Health. The Presence of radionuclides in sewage sludge and their effect on human health. WDOH/320-013. http://www.doh.wa.gov/ehp/rp/environmental [Accessed 13 August 2008]
28. 131I for hyperthyroidism. Med Phys 2004; 31:3194-3200.
29. Marriot CJ, Weber CE, Gulenchyn KY. Radiation exposure for 'caregivers' during high-dose outpatient radioiodine therapy. Radiat Prot Dosim 2007; 123:62-67.
30. Mountford PJ, O'Doherty MJ. Exposure of critical groups to nuclear medicine patients. Appl Radiat Isot 1999; 50 :89-111.
31. Pant GS. Dosimetric and radiation safety considerations in radioiodine therapy. Ind J Nucl Med 2005; 20:1-3.
32. Ibis E, Wilson CR, Collier BD, Akansel G, Isitman AT, Yoss RG. Iodine-131 contamination from thyroid cancer patient. J Nucl Med 1992; 33:2110-2115.
33. Aurengo A. Chernobyl: the effects on public health? Physics and Society 2002. http://units.aps.org/units/fps/newsletters/2002/october/index.cfm [Accessed 13 August 2008]
34. González AJ. Regulation of low-level radiation. C R Acad Sci III 1999; 322:241-243.
35. Health Physics Society. Radiation risk in perspective. Position Statement of the Health Physics Society 2004. http://www.hps.org/documents/ radiationrisk.pdf [Accessed 13 August 2008]
36. American Nuclear Society. Health effects of low-level radiation. Position Statement 41; 2001. http://www.ans.org/pi/ps/docs/ps41.pdf [Accessed 13 August 2008]
37. USNRC. Instruction concerning risks from occupational radiation exposure. Regulatory Guide 8.29.
38. Rockwell T. The realism project: it's time to get real. Nucl News 2004; 47:10-12.
39. Mehta SC. Health risks of low level radiation exposures: a review. Ind J Nucl Med 2005; 20:29-41.