Antitumor activity of pyridoisoquinoline derivatives F91873 and F91874, novel multikinase inhibitors with activity against the anaplastic lymphoma kinase.

Anti-cancer drugs

Volumn 20, Issue 5, 2009, Pages 364-372

  Kruczynski, Anna ^a   Mayer, Patrice ^a   Marchand, Arnaud ^a   Vispé, Stéphane ^a   Fournier, Emmanuel ^a   Annereau, Jean Philippe ^a   Brel, Viviane ^a   Barret, Jean Marc ^a   Delsol, Georges ^a   Imbert, Thierry ^a   Fahy, Jacques ^a   Bailly, Christian ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; ANTINEOPLASTIC AGENT; F 91873; F 91874; HYBRID PROTEIN; P80(NPM ALK) PROTEIN; P80(NPM-ALK) PROTEIN; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; QUINOLIZINE DERIVATIVE; THIAZOLE DERIVATIVE;

ANIMAL; ARTICLE; CELL CYCLE G1 PHASE; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; FEMALE; INSTITUTE FOR CANCER RESEARCH MOUSE; LARGE CELL LYMPHOMA; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MOUSE; MOUSE MUTANT; OVARY TUMOR; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; FEMALE; G1 PHASE; LUNG NEOPLASMS; LYMPHOMA, LARGE-CELL, ANAPLASTIC; MICE; MICE, INBRED ICR; MICE, SCID; OVARIAN NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; QUINOLIZINES; RECOMBINANT FUSION PROTEINS; THIAZOLES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MLCS; MLOWN;

EID: 67650312000     PISSN: None     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/cad.0b013e32832a2ed9     Document Type: Article

References (0)