-
1
-
-
0027176364
-
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
-
DOI 10.1038/ng0893-398
-
Andrew, S. E., Goldberg, Y. P., Kremer, B., Telenius, H., Theilmann, J., Adam, S., Starr, E., Squitieri, F., Lin, B., Kalchman, M. A. et al. (1993). The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease. Nat. Genet. 4, 398-403. (Pubitemid 23231490)
-
(1993)
Nature Genetics
, vol.4
, Issue.4
, pp. 398-403
-
-
Andrew, S.E.1
Goldberg, Y.P.2
Kremer, B.3
Telenius, H.4
Theilmann, J.5
Adam, S.6
Starr, E.7
Squitieri, F.8
Lin, B.9
Kalchman, M.A.10
Graham, R.K.11
Hayden, M.R.12
-
2
-
-
0031690239
-
Polyglutamine expansion and Huntington's disease
-
Bates, G. P., Mangiarini, L., Wanker, E. E. and Davies, S. W. (1998). Polyglutamine expansion and Huntington's disease. Biochem. Soc. Trans. 26, 471-475.
-
(1998)
Biochem. Soc. Trans.
, vol.26
, pp. 471-475
-
-
Bates, G.P.1
Mangiarini, L.2
Wanker, E.E.3
Davies, S.W.4
-
3
-
-
29444455075
-
Drosophila as a model for human neurodegenerative disease
-
DOI 10.1146/annurev.genet.39.110304.095804
-
Bilen, J. and Bonini, N. M. (2005). Drosophila as a model for human neurodegenerative disease. Annu. Rev. Genet. 39, 153-171. (Pubitemid 43011111)
-
(2005)
Annual Review of Genetics
, vol.39
, pp. 153-171
-
-
Bilen, J.1
Bonini, N.M.2
-
4
-
-
0035282594
-
Loss of normal huntingtin function: New developments in Huntington's disease research
-
DOI 10.1016/S0166-2236(00)01721-5, PII S0166223600017215
-
Cattaneo, E., Rigamonti, D., Goffredo, D., Zuccato, C., Squitieri, F. and Sipione, S. (2001). Loss of normal huntingtin function: new developments in Huntington's disease research. Trends Neurosci. 24, 182-188. (Pubitemid 32166824)
-
(2001)
Trends in Neurosciences
, vol.24
, Issue.3
, pp. 182-188
-
-
Cattaneo, E.1
Rigamonti, D.2
Goffredo, D.3
Zuccato, C.4
Squitieri, F.5
Sipione, S.6
-
5
-
-
0029082383
-
Inactivation of the mouse Huntington's disease gene homolog Hdh
-
Duyao, M. P., Auerbach, A. B., Ryan, A., Persichetti, F., Barnes, G. T., McNeil, S. M., Ge, P., Vonsattel, J. P., Gusella, J. F., Joyner, A. L. et al. (1995). Inactivation of the mouse Huntington's disease gene homolog Hdh. Science 269, 407-410.
-
(1995)
Science
, vol.269
, pp. 407-410
-
-
Duyao, M.P.1
Auerbach, A.B.2
Ryan, A.3
Persichetti, F.4
Barnes, G.T.5
McNeil, S.M.6
Ge, P.7
Vonsattel, J.P.8
Gusella, J.F.9
Joyner, A.L.10
-
6
-
-
45149107487
-
Mechanisms of neurodegeneration in Huntington's disease
-
Gil, J. M. and Rego, A. C. (2008). Mechanisms of neurodegeneration in Huntington's disease. Eur. J. Neurosci. 27, 2803-2820.
-
(2008)
Eur. J. Neurosci.
, vol.27
, pp. 2803-2820
-
-
Gil, J.M.1
Rego, A.C.2
-
7
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
DOI 10.1016/S0896-6273(03)00594-4
-
Gunawardena, S., Her, L. S., Brusch, R. G., Laymon, R. A., Niesman, I. R., Gordesky-Gold, B., Sintasath, L., Bonini, N. M. and Goldstein, L. S. (2003). Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron 40, 25-40. (Pubitemid 37222462)
-
(2003)
Neuron
, vol.40
, Issue.1
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.-S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
Sintasath, L.7
Bonini, N.M.8
Goldstein, L.S.B.9
-
8
-
-
44449131447
-
Huntington's disease: From pathology and genetics to potential therapies
-
DOI 10.1042/BJ20071619
-
Imarisio, S., Carmichael, J., Korolchuk, V., Chen, C. W., Saiki, S., Rose, C., Krishna, G., Davies, J. E., Ttofi, E., Underwood, B. R. et al. (2008). Huntington's disease: from pathology and genetics to potential therapies. Biochem. J. 412, 191-209. (Pubitemid 351758226)
-
(2008)
Biochemical Journal
, vol.412
, Issue.2
, pp. 191-209
-
-
Imarisio, S.1
Carmichael, J.2
Korolchuk, V.3
Chen, C.-W.4
Saiki, S.5
Rose, C.6
Krishna, G.7
Davies, J.E.8
Ttofi, E.9
Underwood, B.R.10
Rubinsztein, D.C.11
-
9
-
-
0032168160
-
Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons
-
DOI 10.1016/S0896-6273(00)80573-5
-
Jackson, G. R., Salecker, I., Dong, X., Yao, X., Arnheim, N., Faber, P. W., MacDonald, M. E. and Zipursky, S. L. (1998). Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron 21, 633-642. (Pubitemid 28475514)
-
(1998)
Neuron
, vol.21
, Issue.3
, pp. 633-642
-
-
Jackson, G.R.1
Salecker, I.2
Dong, X.3
Yao, X.4
Arnheim, N.5
Faber, P.W.6
MacDonald, M.E.7
Zipursky, S.L.8
-
10
-
-
0032855148
-
A putative Drosophila homolog of the Huntington's disease gene
-
DOI 10.1093/hmg/8.9.1807
-
Li, Z., Karlovich, C. A., Fish, M. P., Scott, M. P. and Myers, R. M. (1999). A putative Drosophila homolog of the Huntington's disease gene. Hum. Mol. Genet. 8, 1807-1815. (Pubitemid 29423893)
-
(1999)
Human Molecular Genetics
, vol.8
, Issue.9
, pp. 1807-1815
-
-
Li, Z.1
Karlovich, C.A.2
Fish, M.P.3
Scott, M.P.4
Myers, R.M.5
-
11
-
-
0029055717
-
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
-
Nasir, J., Floresco, S. B., O'Kusky, J. R., Diewert, V. M., Richman, J. M., Zeisler, J., Borowski, A., Marth, J. D., Phillips, A. G. and Hayden, M. R. (1995). Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Cell 81, 811-823.
-
(1995)
Cell
, vol.81
, pp. 811-823
-
-
Nasir, J.1
Floresco, S.B.2
O'Kusky, J.R.3
Diewert, V.M.4
Richman, J.M.5
Zeisler, J.6
Borowski, A.7
Marth, J.D.8
Phillips, A.G.9
Hayden, M.R.10
-
12
-
-
0029997090
-
Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats
-
Rubinsztein, D. C., Leggo, J., Coles, R., Almqvist, E., Biancalana, V., Cassiman, J. J., Chotai, K., Connarty, M., Crauford, D., Curtis, A. et al. (1996). Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. Am. J. Hum. Genet. 59, 16-22.
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 16-22
-
-
Rubinsztein, D.C.1
Leggo, J.2
Coles, R.3
Almqvist, E.4
Biancalana, V.5
Cassiman, J.J.6
Chotai, K.7
Connarty, M.8
Crauford, D.9
Curtis, A.10
-
13
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutaminedependent neurodegeneration in Drosophila
-
Steffan, J. S., Bodai, L., Pallos, J., Poelman, M., McCampbell, A., Apostol, B. L., Kazantsev, A., Schmidt, E., Zhu, Y. Z., Greenwald, M. et al. (2001). Histone deacetylase inhibitors arrest polyglutaminedependent neurodegeneration in Drosophila. Nature 413, 739-743.
-
(2001)
Nature
, vol.413
, pp. 739-743
-
-
Steffan, J.S.1
Bodai, L.2
Pallos, J.3
Poelman, M.4
McCampbell, A.5
Apostol, B.L.6
Kazantsev, A.7
Schmidt, E.8
Zhu, Y.Z.9
Greenwald, M.10
-
14
-
-
84993912315
-
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
-
Zeitlin, S., Liu, J. P., Chapman, D. L., Papaioannou, V. E. and Efstratiadis, A. (1995). Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue. Nat. Genet. 11, 155-163.
-
(1995)
Nat. Genet.
, vol.11
, pp. 155-163
-
-
Zeitlin, S.1
Liu, J.P.2
Chapman, D.L.3
Papaioannou, V.E.4
Efstratiadis, A.5
-
15
-
-
67650296271
-
Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model
-
Zhang, S., Feany, M. B., Saraswati, S., Littleton, J. T. and Perrimon, N. (2009). Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Dis. Model. Mech. 2, 247-266.
-
(2009)
Dis. Model. Mech.
, vol.2
, pp. 247-266
-
-
Zhang, S.1
Feany, M.B.2
Saraswati, S.3
Littleton, J.T.4
Perrimon, N.5
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