메뉴 건너뛰기




Volumn 14, Issue 2, 2009, Pages

Time-gated flow cytometry: An ultra-high selectivity method to recover ultra-rare-event μ-targets in high-background biosamples

Author keywords

autofluorescence; europium; flow cytometry; Giardia; rare event; time gated luminescence (TGL); true positive; UV LED

Indexed keywords

AUTOFLUORESCENCE; GIARDIA; RARE EVENT; TIME-GATED LUMINESCENCE (TGL); TRUE POSITIVE; UV LED;

EID: 67650289822     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3103770     Document Type: Article
Times cited : (39)

References (41)
  • 1
    • 34447523459 scopus 로고    scopus 로고
    • Rare-event analysis in flow cytometry
    • 48j ZZZZZZ 0272-2712 10.1016/j.cll.2007.05.013
    • A. D., Donnenberg and V. S., Donnenberg, " Rare-event analysis in flow cytometry, ", Clin. Lab Med., 27 (3), 627-652 (2007). 48j ZZZZZZ 0272-2712 10.1016/j.cll.2007.05.013
    • (2007) Clin. Lab Med. , vol.27 , Issue.3 , pp. 627-652
    • Donnenberg, A.D.1    Donnenberg, V.S.2
  • 2
    • 18044364593 scopus 로고    scopus 로고
    • Detection and quantification of circulating tumor cells in mouse models of human breast cancer using immunomagnetic enrichment and multiparameter flow cytometry
    • d9r CPAYAV 1552-4922 10.1002/cyto.a.20132
    • A. L., Allan, S. A., Vantyghem, A. B., Tuck, A. F., Chambers, I. H., Chin-Yee, and M., Keeney, " Detection and quantification of circulating tumor cells in mouse models of human breast cancer using immunomagnetic enrichment and multiparameter flow cytometry, ", Cytometry, Part A, 65A (1), 4-14 (2005). d9r CPAYAV 1552-4922 10.1002/cyto.a.20132
    • (2005) Cytometry, Part A , vol.65 , Issue.1 , pp. 4-14
    • Allan, A.L.1    Vantyghem, S.A.2    Tuck, A.B.3    Chambers, A.F.4    Chin-Yee, I.H.5    Keeney, M.6
  • 3
    • 0034175615 scopus 로고    scopus 로고
    • Ultra-rare-event detection performance of a custom scanning cytometer on a model preparation of fetal nRBCs
    • cyt CYTODQ 0196-4763 10.1002/(SICI)1097-0320(20000401)39:4<285::AID- CYTO6>3.0.CO;2-2
    • S., Bajaj, J. B., Welsh, R. C., Leif, and J. H., Price, " Ultra-rare-event detection performance of a custom scanning cytometer on a model preparation of fetal nRBCs, ", Cytometry, 39 (4), 285-294 (2000). cyt CYTODQ 0196-4763 10.1002/(SICI)1097-0320(20000401)39:4<285::AID-CYTO6>3.0. CO;2-2
    • (2000) Cytometry , vol.39 , Issue.4 , pp. 285-294
    • Bajaj, S.1    Welsh, J.B.2    Leif, R.C.3    Price, J.H.4
  • 4
    • 33750478692 scopus 로고    scopus 로고
    • Optimization of a flow cytometry-based protocol for detection and phenotypic characterization of multipotent mesenchymal stromal cells from human bone marrow
    • d9s CPBCB5 1552-4949 10.1002/cyto.b.20118
    • E. A., Jones, A., English, S. E., Kinsey, L., Straszynski, P., Emery, F., Ponchel, and D., McGonagle, " Optimization of a flow cytometry-based protocol for detection and phenotypic characterization of multipotent mesenchymal stromal cells from human bone marrow, ", Cytometry, Part B, 70B (6), 391-399 (2006). d9s CPBCB5 1552-4949 10.1002/cyto.b.20118
    • (2006) Cytometry, Part B , vol.70 , Issue.6 , pp. 391-399
    • Jones, E.A.1    English, A.2    Kinsey, S.E.3    Straszynski, L.4    Emery, P.5    Ponchel, F.6    McGonagle, D.7
  • 5
    • 33749041711 scopus 로고    scopus 로고
    • In vivo, selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes, in vivo
    • 5de ZZZZZZ 0168-8278 10.1016/j.jhe2006.04.012
    • K., Yamaguchi, K., Itoh, T., Masuda, A., Umemura, C., Baum, Y., Itoh, T., Okanoue, and J., Fujita, " In vivo, selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes, in vivo, ", J. Hepatol, 45 (5), 681-687 (2006). 5de ZZZZZZ 0168-8278 10.1016/j.jhep.2006.04.012
    • (2006) J. Hepatol , vol.45 , Issue.5 , pp. 681-687
    • Yamaguchi, K.1    Itoh, K.2    Masuda, T.3    Umemura, A.4    Baum, C.5    Itoh, Y.6    Okanoue, T.7    Fujita, J.8
  • 6
    • 0348135033 scopus 로고    scopus 로고
    • Analysis-only detection of Giardia by combining immunomagnetic separation and two-color flow cytometry
    • d9r CPAYAV 1552-4922 10.1002/cyto.a.10009
    • B. C., Ferrari and D., Veal, " Analysis-only detection of Giardia by combining immunomagnetic separation and two-color flow cytometry, ", Cytometry, Part A, 51A (2), 79-86 (2003). d9r CPAYAV 1552-4922 10.1002/cyto.a.10009
    • (2003) Cytometry, Part A , vol.51 , Issue.2 , pp. 79-86
    • Ferrari, B.C.1    Veal, D.2
  • 7
    • 3242746899 scopus 로고    scopus 로고
    • Effects of seeding procedures and water quality on recovery of, Cryptosporidium, oocysts from stream water by using US environmental protection agency method 1623
    • 2jv AEMIDF 0099-2240 10.1128/AEM.70.7.4118-4128.2004
    • D. S., Francy, O. D., Simmons, M. W., Ware, E. J., Granger, M. D., Sobsey, and F. W., Schaefer, " Effects of seeding procedures and water quality on recovery of, Cryptosporidium, oocysts from stream water by using US environmental protection agency method 1623, ", Appl. Environ. Microbiol., 70 (7), 4118-4128 (2004). 2jv AEMIDF 0099-2240 10.1128/AEM.70.7.4118-4128.2004
    • (2004) Appl. Environ. Microbiol. , vol.70 , Issue.7 , pp. 4118-4128
    • Francy, D.S.1    Simmons, O.D.2    Ware, M.W.3    Granger, E.J.4    Sobsey, M.D.5    Schaefer, F.W.6
  • 8
    • 34548177231 scopus 로고    scopus 로고
    • Lab-on-a-chip devices for microbial monitoring and detection in water
    • cny WSTWBM 1606-9749 10.2166/ws.2007.051
    • W.-T., Liu and C., Lay, " Lab-on-a-chip devices for microbial monitoring and detection in water, ", Water Sci. Technol.: Water Supply, 7 (2), 165-172 (2007). cny WSTWBM 1606-9749 10.2166/ws.2007.051
    • (2007) Water Sci. Technol.: Water Supply , vol.7 , Issue.2 , pp. 165-172
    • Liu, W.-T.1    Lay, C.2
  • 10
    • 0028836795 scopus 로고
    • Model study detecting breast-cancer cells in peripheral-blood mononuclear-cells at frequencies as low as, 10(-7)
    • pna PNASA6 0027-8424 10.1073/pnas.92.2.537
    • H. J., Gross, B., Verwer, D., Houck, R. A., Hoffman, and D., Recktenwald, " Model study detecting breast-cancer cells in peripheral-blood mononuclear-cells at frequencies as low as, 10(-7), ", Proc. Natl. Acad. Sci. U.S.A., 92 (2), 537-541 (1995). pna PNASA6 0027-8424 10.1073/pnas.92.2.537
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , Issue.2 , pp. 537-541
    • Gross, H.J.1    Verwer, B.2    Houck, D.3    Hoffman, R.A.4    Recktenwald, D.5
  • 11
    • 34447293285 scopus 로고    scopus 로고
    • Spot counting to locate fetal cells in maternal blood and tissue: A comparison of manual and automated microscopy
    • mru MRTEEO 1059-910X 10.1002/jemt.20439
    • K. L., Johnson, H., Stroh, K., Khosrotehrani, and D. W., Bianchi, " Spot counting to locate fetal cells in maternal blood and tissue: a comparison of manual and automated microscopy, ", Microsc. Res. Tech., 70 (7), 585-588 (2007). mru MRTEEO 1059-910X 10.1002/jemt.20439
    • (2007) Microsc. Res. Tech. , vol.70 , Issue.7 , pp. 585-588
    • Johnson, K.L.1    Stroh, H.2    Khosrotehrani, K.3    Bianchi, D.W.4
  • 12
    • 0030034519 scopus 로고    scopus 로고
    • Male fetal progenitor cells persist in maternal blood for as long as, 27years, postpartum
    • pna PNASA6 0027-8424 10.1073/pnas.93.2.705
    • D. W., Bianchi, G. K., Zickwolf, G. J., Weil, S., Sylvester, and M. A., DeMaria, " Male fetal progenitor cells persist in maternal blood for as long as, 27years, postpartum, ", Proc. Natl. Acad. Sci. U.S.A., 93 (2), 705-708 (1996). pna PNASA6 0027-8424 10.1073/pnas.93.2.705
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , Issue.2 , pp. 705-708
    • Bianchi, D.W.1    Zickwolf, G.K.2    Weil, G.J.3    Sylvester, S.4    Demaria, M.A.5
  • 13
    • 0034699494 scopus 로고    scopus 로고
    • Fluorescence staining and flow cytometry for monitoring microbial cells
    • 5e7 JIMMBG 0022-1759 10.1016/S0022-1759(00)00234-9
    • D. A., Veal, D., Deere, B., Ferrari, J., Piper, and P. V., Attfield, " Fluorescence staining and flow cytometry for monitoring microbial cells, ", J. Immunol. Methods, 243 (1-2), 191-210 (2000). 5e7 JIMMBG 0022-1759 10.1016/S0022-1759(00)00234-9
    • (2000) J. Immunol. Methods , vol.243 , Issue.12 , pp. 191-210
    • Veal, D.A.1    Deere, D.2    Ferrari, B.3    Piper, J.4    Attfield, P.V.5
  • 14
    • 0035965096 scopus 로고    scopus 로고
    • Comparative assessment of epifluorescence microscopy, flow cytometry, and solid-phase cytometry used in the enumeration of specific bacteria in water
    • crl ZZZZZZ 0948-3055 10.3354/ame025301
    • K., Lemarchand, N., Parthuisot, P., Catala, and P., Lebaron, " Comparative assessment of epifluorescence microscopy, flow cytometry, and solid-phase cytometry used in the enumeration of specific bacteria in water, ", Aquat. Microb. Ecol., 25 (3), 301-309 (2001). crl ZZZZZZ 0948-3055 10.3354/ame025301
    • (2001) Aquat. Microb. Ecol. , vol.25 , Issue.3 , pp. 301-309
    • Lemarchand, K.1    Parthuisot, N.2    Catala, P.3    Lebaron, P.4
  • 15
    • 0003544950 scopus 로고    scopus 로고
    • 4th ed., John Wiley & Sons, Inc., Hoboken, NJ
    • H. M., Shapiro, Practical Flow Cytometry, 4th ed., John Wiley & Sons, Inc., Hoboken, NJ (2002).
    • (2002) Practical Flow Cytometry
    • Shapiro, H.M.1
  • 16
    • 31844445580 scopus 로고    scopus 로고
    • Applying fluorescence-based technology to the recovery and isolation of, Cryptosporidium, and, Giardia, from industrial wastewater streams
    • 96e WATRAG 0043-1354 10.1016/j.watres.2005.11.037
    • B. C., Ferrari, K., Stoner, and P. L., Bergquist, " Applying fluorescence-based technology to the recovery and isolation of, Cryptosporidium, and, Giardia, from industrial wastewater streams, ", Water Res., 40 (3), 541-548 (2006). 96e WATRAG 0043-1354 10.1016/j.watres.2005.11.037
    • (2006) Water Res. , vol.40 , Issue.3 , pp. 541-548
    • Ferrari, B.C.1    Stoner, K.2    Bergquist, P.L.3
  • 17
    • 0028127180 scopus 로고
    • Detection of low-levels of specific salmonella species by fluorescent-antibodies and flow-cytometry
    • 574 JABAA4 0021-8847
    • R. G., McClelland and A. C., Pinder, " Detection of low-levels of specific salmonella species by fluorescent-antibodies and flow-cytometry, ", J. Appl. Bacteriol., 77 (4), 440-447 (1994). 574 JABAA4 0021-8847
    • (1994) J. Appl. Bacteriol. , vol.77 , Issue.4 , pp. 440-447
    • McClelland, R.G.1    Pinder, A.C.2
  • 18
    • 35349018607 scopus 로고    scopus 로고
    • Practical time-gated luminescence flow cytometry: I. Concepts
    • d9r CPAYAV 1552-4922 10.1002/cyto.a.20450
    • D., Jin, R., Connally, and J., Piper, " Practical time-gated luminescence flow cytometry: I. Concepts, ", Cytometry, Part A, 71A (10), 783-796 (2007). d9r CPAYAV 1552-4922 10.1002/cyto.a.20450
    • (2007) Cytometry, Part A , vol.71 , Issue.10 , pp. 783-796
    • Jin, D.1    Connally, R.2    Piper, J.3
  • 19
    • 35348949632 scopus 로고    scopus 로고
    • Practical time-gated luminescence flow cytometry: II. Experimental evaluation using UV LED excitation
    • d9r CPAYAV 1552-4922 10.1002/cyto.a.20449
    • D., Jin, R., Connally, and J., Piper, " Practical time-gated luminescence flow cytometry: II. Experimental evaluation using UV LED excitation, ", Cytometry, Part A, 71A (10), 797-808 (2007). d9r CPAYAV 1552-4922 10.1002/cyto.a.20449
    • (2007) Cytometry, Part A , vol.71 , Issue.10 , pp. 797-808
    • Jin, D.1    Connally, R.2    Piper, J.3
  • 20
    • 67650283765 scopus 로고    scopus 로고
    • Calibration beads containing luminescent lanthanide ion complexes
    • JBOPFO 1083-3668 10.1117/1.3103646
    • R. C., Leif, D., Jin, J., Piper, L. M., Vallarino, J. W., Williams, S., Yang, and R. M., Zucker, " Calibration beads containing luminescent lanthanide ion complexes, ", J. Biomed. Opt., 14 (2), 024022 (2009). JBOPFO 1083-3668 10.1117/1.3103646
    • (2009) J. Biomed. Opt. , vol.14 , Issue.2 , pp. 024022
    • Leif, R.C.1    Jin, D.2    Piper, J.3    Vallarino, L.M.4    Williams, J.W.5    Yang, S.6    Zucker, R.M.7
  • 21
    • 0031574198 scopus 로고    scopus 로고
    • Highly sensitive time-resolved fluoroimmunoassay of human immunoglobulin e by using a new europium fluorescent chelate as a label
    • ana ANBCA2 0003-2697 10.1006/abio.1997.2444
    • J. L., Yuan, G. L., Wang, H., Kimura, and K., Matsumoto, " Highly sensitive time-resolved fluoroimmunoassay of human immunoglobulin E by using a new europium fluorescent chelate as a label, ", Anal. Biochem., 254 (2), 283-287 (1997). ana ANBCA2 0003-2697 10.1006/abio.1997.2444
    • (1997) Anal. Biochem. , vol.254 , Issue.2 , pp. 283-287
    • Yuan, J.L.1    Wang, G.L.2    Kimura, H.3    Matsumoto, K.4
  • 22
    • 0027225669 scopus 로고
    • A new method for the concentration of cryptosporidium oocysts from water
    • 574 JABAA4 0021-8847
    • G., Vesey, J. S., Slade, M., Byrne, K., Shepherd, and C. R., Fricker, " A new method for the concentration of cryptosporidium oocysts from water, ", J. Appl. Bacteriol., 75 (1), 82-86 (1993). 574 JABAA4 0021-8847
    • (1993) J. Appl. Bacteriol. , vol.75 , Issue.1 , pp. 82-86
    • Vesey, G.1    Slade, J.S.2    Byrne, M.3    Shepherd, K.4    Fricker, C.R.5
  • 23
    • 31144437154 scopus 로고    scopus 로고
    • Long-lived visible luminescence of UV LEDs and impact on LED excited time-resolved fluorescence applications
    • jpd JPAPBE 0022-3727 10.1088/0022-3727/39/3/006
    • D., Jin, R., Connally, and J., Piper, " Long-lived visible luminescence of UV LEDs and impact on LED excited time-resolved fluorescence applications, ", J. Phys. D, 39 (3), 461-465 (2006). jpd JPAPBE 0022-3727 10.1088/0022-3727/39/3/006
    • (2006) J. Phys. D , vol.39 , Issue.3 , pp. 461-465
    • Jin, D.1    Connally, R.2    Piper, J.3
  • 24
    • 33749500697 scopus 로고    scopus 로고
    • High intensity solid-state UV source for time-gated luminescence microscopy
    • d9r CPAYAV 1552-4922 10.1002/cyto.a.20326
    • R., Connally, D. Y., Jin, and J., Piper, " High intensity solid-state UV source for time-gated luminescence microscopy, ", Cytometry, Part A, 69A (9), 1020-1027 (2006). d9r CPAYAV 1552-4922 10.1002/cyto.a.20326
    • (2006) Cytometry, Part A , vol.69 , Issue.9 , pp. 1020-1027
    • Connally, R.1    Jin, D.Y.2    Piper, J.3
  • 25
    • 0030754946 scopus 로고    scopus 로고
    • Evaluation of fluorochromes and excitation sources for immunofluorescence in water samples
    • cyt CYTODQ 0196-4763 10.1002/(SICI)1097-0320(19971001)29:2<147::AID- CYTO7>3.0.CO;2-A
    • G., Vesey, D., Deere, M. R., Gauci, K. R., Griffiths, K. L., Williams, and D. A., Veal, " Evaluation of fluorochromes and excitation sources for immunofluorescence in water samples, ", Cytometry, 29 (2), 147-154 (1997). cyt CYTODQ 0196-4763 10.1002/(SICI)1097-0320(19971001)29:2<147::AID- CYTO7>3.0.CO;2-A
    • (1997) Cytometry , vol.29 , Issue.2 , pp. 147-154
    • Vesey, G.1    Deere, D.2    Gauci, M.R.3    Griffiths, K.R.4    Williams, K.L.5    Veal, D.A.6
  • 26
    • 33749124766 scopus 로고    scopus 로고
    • Increasing the luminescence of lanthanide complexes
    • d9r CPAYAV 1552-4922 10.1002/cyto.a.20321
    • R. C., Leif, L. M., Vallarino, M. C., Becker, and S., Yang, " Increasing the luminescence of lanthanide complexes, ", Cytometry, Part A, 69A (8), 767-778 (2006). d9r CPAYAV 1552-4922 10.1002/cyto.a.20321
    • (2006) Cytometry, Part A , vol.69 , Issue.8 , pp. 767-778
    • Leif, R.C.1    Vallarino, L.M.2    Becker, M.C.3    Yang, S.4
  • 27
    • 0030939430 scopus 로고    scopus 로고
    • Theoretical basis for sampling statistics useful for detecting and isolating rare cells using flow cytometry and cell sorting
    • cyt CYTODQ 0196-4763 10.1002/(SICI)1097-0320(19970301)27:3<233::AID- CYTO4>3.0.CO;2-F
    • J. I., Rosenblatt, J. A., Hokanson, S. R., McLaughlin, and J. F., Leary, " Theoretical basis for sampling statistics useful for detecting and isolating rare cells using flow cytometry and cell sorting, ", Cytometry, 27 (3), 233-238 (1997). cyt CYTODQ 0196-4763 10.1002/(SICI)1097-0320(19970301) 27:3<233::AID-CYTO4>3.0.CO;2-F
    • (1997) Cytometry , vol.27 , Issue.3 , pp. 233-238
    • Rosenblatt, J.I.1    Hokanson, J.A.2    McLaughlin, S.R.3    Leary, J.F.4
  • 28
    • 33749144057 scopus 로고    scopus 로고
    • Increasing lanthanide luminescence by use of the RETEL effect
    • d9r CPAYAV 1552-4922 10.1002/cyto.a.20318
    • R. C., Leif, L. M., Vallarino, M. C., Becker, and S., Yang, " Increasing lanthanide luminescence by use of the RETEL effect, ", Cytometry, Part A, 69A (8), 940-946 (2006). d9r CPAYAV 1552-4922 10.1002/cyto.a.20318
    • (2006) Cytometry, Part A , vol.69 , Issue.8 , pp. 940-946
    • Leif, R.C.1    Vallarino, L.M.2    Becker, M.C.3    Yang, S.4
  • 29
    • 0346874410 scopus 로고    scopus 로고
    • Fluorescence lifetime-based discrimination and quantification of cellular DNA and RNA with phase-sensitive flow cytometry
    • d9r CPAYAV 1552-4922 10.1002/cyto.a.10022
    • H. H., Cui, J. G., Valdez, J. A., Steinkamp, and H. A., Crissman, " Fluorescence lifetime-based discrimination and quantification of cellular DNA and RNA with phase-sensitive flow cytometry, ", Cytometry, Part A, 52A (1), 46-55 (2003). d9r CPAYAV 1552-4922 10.1002/cyto.a.10022
    • (2003) Cytometry, Part A , vol.52 , Issue.1 , pp. 46-55
    • Cui, H.H.1    Valdez, J.G.2    Steinkamp, J.A.3    Crissman, H.A.4
  • 30
    • 0000435751 scopus 로고    scopus 로고
    • Time-resolved fluorescence-decay measurement and analysis on single cells by flow cytometry
    • apo APOPAI 0003-6935 10.1364/AO.35.004481
    • C., Deka and J. A., Steinkamp, " Time-resolved fluorescence-decay measurement and analysis on single cells by flow cytometry, ", Appl. Opt., 35 (22), 4481-4489 (1996). apo APOPAI 0003-6935 10.1364/AO.35.004481
    • (1996) Appl. Opt. , vol.35 , Issue.22 , pp. 4481-4489
    • Deka, C.1    Steinkamp, J.A.2
  • 31
    • 0031563819 scopus 로고    scopus 로고
    • Monitoring uptake of ellipticine and its fluorescence lifetime in relation to the cell cycle phase by flow cytometry
    • ecr ECREAL 0014-4827 10.1006/excr.1997.3717
    • B. L., Sailer, J. G., Valdez, J. A., Steinkamp, Z., Darzynkiewicz, and H. A., Crissman, " Monitoring uptake of ellipticine and its fluorescence lifetime in relation to the cell cycle phase by flow cytometry, ", Exp. Cell Res., 236 (1), 259-267 (1997). ecr ECREAL 0014-4827 10.1006/excr.1997.3717
    • (1997) Exp. Cell Res. , vol.236 , Issue.1 , pp. 259-267
    • Sailer, B.L.1    Valdez, J.G.2    Steinkamp, J.A.3    Darzynkiewicz, Z.4    Crissman, H.A.5
  • 32
    • 0027407799 scopus 로고
    • Resolution of fluorescence signals from cells labeled with fluorochromes having different lifetimes by phase-sensitive flow-cytometry
    • cyt CYTODQ 0196-4763 10.1002/cyto.990140214
    • J. A., Steinkamp and H. A., Crissman, " Resolution of fluorescence signals from cells labeled with fluorochromes having different lifetimes by phase-sensitive flow-cytometry, ", Cytometry, 14 (2), 210-216 (1993). cyt CYTODQ 0196-4763 10.1002/cyto.990140214
    • (1993) Cytometry , vol.14 , Issue.2 , pp. 210-216
    • Steinkamp, J.A.1    Crissman, H.A.2
  • 33
    • 0033485335 scopus 로고    scopus 로고
    • Enhanced immunofluorescence measurement resolution of surface antigens on highly autofluorescent, glutaraldehyde-fixed cells analyzed by phase-sensitive flow cytometry
    • cyt CYTODQ 0196-4763 10.1002/(SICI)1097-0320(19991201)37:4<275::AID- CYTO4>3.0.CO;2-U
    • J. A., Steinkamp, N. M., Lehnert, J. F., Keij, and B. E., Lehnert, " Enhanced immunofluorescence measurement resolution of surface antigens on highly autofluorescent, glutaraldehyde-fixed cells analyzed by phase-sensitive flow cytometry, ", Cytometry, 37 (4), 275-283 (1999). cyt CYTODQ 0196-4763 10.1002/(SICI)1097-0320(19991201)37:4<275::AID-CYTO4>3.0.CO;2-U
    • (1999) Cytometry , vol.37 , Issue.4 , pp. 275-283
    • Steinkamp, J.A.1    Lehnert, N.M.2    Keij, J.F.3    Lehnert, B.E.4
  • 34
    • 0032809173 scopus 로고    scopus 로고
    • Discrimination of damaged/dead cells by propidium iodide uptake in immunofluorescently labeled populations analyzed by phase-sensitive flow cytometry
    • 5e7 JIMMBG 0022-1759 10.1016/S0022-1759(99)00053-8
    • J. A., Steinkamp, B. E., Lehnert, and N. M., Lehnert, " Discrimination of damaged/dead cells by propidium iodide uptake in immunofluorescently labeled populations analyzed by phase-sensitive flow cytometry, ", J. Immunol. Methods, 226 (1-2), 59-70 (1999). 5e7 JIMMBG 0022-1759 10.1016/S0022-1759(99)00053-8
    • (1999) J. Immunol. Methods , vol.226 , Issue.12 , pp. 59-70
    • Steinkamp, J.A.1    Lehnert, B.E.2    Lehnert, N.M.3
  • 35
    • 0032679263 scopus 로고    scopus 로고
    • Addition of a second lanthanide ion to increase the luminescence of europium(III) macrocyclic complexes
    • spi PSISDG 0277-786X 10.1117/12.349209
    • A. J., Bromm, Jr., R. C., Leif, J. R., Quagliano, and L. M., Vallarino, " Addition of a second lanthanide ion to increase the luminescence of europium(III) macrocyclic complexes, ", Proc. SPIE, 3604, 263-272 (1999). spi PSISDG 0277-786X 10.1117/12.349209
    • (1999) Proc. SPIE , vol.3604 , pp. 263-272
    • Bromm Jr., A.J.1    Leif, R.C.2    Quagliano, J.R.3    Vallarino, L.M.4
  • 36
    • 0036060724 scopus 로고    scopus 로고
    • Optimizing the luminescence of lanthanide(III) macrocyclic complexes for the detection of anti-5BrdU
    • spi PSISDG 0277-786X 10.1117/12.468350
    • R. C., Leif, M. C., Becker, A. J., Bromm, Jr., L. M., Vallarino, J. W., Williams, S. A., Williams, and S., Yang, " Optimizing the luminescence of lanthanide(III) macrocyclic complexes for the detection of anti-5BrdU, ", Proc. SPIE, 4622, 250-261 (2002). spi PSISDG 0277-786X 10.1117/12.468350
    • (2002) Proc. SPIE , vol.4622 , pp. 250-261
    • Leif, R.C.1    Becker, M.C.2    Bromm Jr., A.J.3    Vallarino, L.M.4    Williams, J.W.5    Williams, S.A.6    Yang, S.7
  • 37
    • 33745300008 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer enhanced luminescence (FRETEL) of Quantum Dyes
    • spi PSISDG 0277-786X
    • R. C., Leif, M. C., Becker, A. J., Bromm, Jr., L. M., Vallarino, and S., Yang, " Fluorescence resonance energy transfer enhanced luminescence (FRETEL) of Quantum Dyes, ", Proc. SPIE, 6092, 29-41 (2006). spi PSISDG 0277-786X
    • (2006) Proc. SPIE , vol.6092 , pp. 29-41
    • Leif, R.C.1    Becker, M.C.2    Bromm Jr., A.J.3    Vallarino, L.M.4    Yang, S.5
  • 39
    • 0034944470 scopus 로고    scopus 로고
    • Increasing the luminescence of lanthanide(III) macrocyclic complexes by the use of polymers and lanthanide enhanced luminescence
    • spi PSISDG 0277-786X 10.1117/12.426770
    • R. C., Leif, M. C., Becker, A. J., Bromm, Jr., L. M., Vallarino, S. A., Williams, and S., Yang, " Increasing the luminescence of lanthanide(III) macrocyclic complexes by the use of polymers and lanthanide enhanced luminescence, ", Proc. SPIE, 4260, 184-197 (2001). spi PSISDG 0277-786X 10.1117/12.426770
    • (2001) Proc. SPIE , vol.4260 , pp. 184-197
    • Leif, R.C.1    Becker, M.C.2    Bromm Jr., A.J.3    Vallarino, L.M.4    Williams, S.A.5    Yang, S.6
  • 40
    • 37749038948 scopus 로고    scopus 로고
    • Luminescent europium nanoparticles with a wide excitation range from UV to visible light for biolabeling and time-gated luminescence bioimaging
    • ccg CHCOFS 1359-7345 10.1039/b715054g
    • J., Wu, G. L., Wang, D. Y., Jin, J. L., Yuan, Y. F., Guan, and J., Piper, " Luminescent europium nanoparticles with a wide excitation range from UV to visible light for biolabeling and time-gated luminescence bioimaging, ", Chem. Commun. (Cambridge), 3, 365-367 (2008). ccg CHCOFS 1359-7345 10.1039/b715054g
    • (2008) Chem. Commun. (Cambridge) , vol.3 , pp. 365-367
    • Wu, J.1    Wang, G.L.2    Jin, D.Y.3    Yuan, J.L.4    Guan, Y.F.5    Piper, J.6
  • 41
    • 0007823621 scopus 로고
    • Markers for instrumental evaluation of cells of the female reproductive tract: Existing and new markers
    • Wied G.L. Bahr G.F. Bartels P.H. and, Eds., p, Tutorials of Cytology, Chicago
    • R. C., Leif, S. P., Clay, H. G., Gratzner, H. G., Haines, K. V., Rao, and L. M., Vallarino; " Markers for instrumental evaluation of cells of the female reproductive tract: Existing and new markers, " in, The Automation of Uterine Cancer Cytology, G. L., Wied, G. F., Bahr, and, P. H., Bartels, Eds., pp. 313-344, Tutorials of Cytology, Chicago (1976).
    • (1976) The Automation of Uterine Cancer Cytology , pp. 313-344
    • Leif, R.C.1    Clay, S.P.2    Gratzner, H.G.3    Haines, H.G.4    Rao, K.V.5    Vallarino, L.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.