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Volumn 72, Issue 14, 2009, Pages 861-869

Comparative covalent protein binding of 2,5-Hexanedione and 3-Acetyl-2,5-Hexanedione in the rat

Author keywords

[No Author keywords available]

Indexed keywords

2,5-HEXANEDIONE; 3 ACETYL 2,5 HEXANEDIONE; 3-ACETYL-2,5-HEXANEDIONE; ACETONYLACETONE; ALKANONE; CYTOSKELETON PROTEIN; DRUG DERIVATIVE; ERGOSTEROL; HEXANE; N-HEXANE; PORTENSTEROL;

EID: 67650287665     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390902959508     Document Type: Article
Times cited : (13)

References (46)
  • 1
    • 0018082460 scopus 로고
    • Role of acid phosphatase in delayed neurotoxicity induced by leptophos in hens
    • DOI 10.1016/0006-2952(78)90066-7
    • Abou-Donia, M. B. 1978. Role of acid phosphatase in delayed neurotoxicity induced by leptophos in hens. Biochem. Pharmacol. 27:2055-2058. (Pubitemid 9043859)
    • (1978) Biochemical Pharmacology , vol.27 , Issue.16 , pp. 2055-2058
    • Abou-Donia, M.B.1
  • 2
    • 37049095158 scopus 로고
    • Electrophilic substitution in pyrroles. Part 1. Reaction with 4-dimethylaminobenzaldehyde (Ehrlich's reagent) in acid solution
    • Alexander, R. S. and Butler, A. R. 1976. Electrophilic substitution in pyrroles. Part 1. Reaction with 4-dimethylaminobenzaldehyde (Ehrlich's reagent) in acid solution. J. Chem. Soc. Perkin Trans. II:696-701.
    • (1976) J. Chem. Soc. Perkin Trans. , vol.2 , pp. 696-701
    • Alexander, R.S.1    Butler, A.R.2
  • 4
    • 0021053768 scopus 로고
    • The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. II. Dimethyl substitution accelerates pyrrole formation and protein crosslinking
    • Anthony, D. C., Boekelheide, K., Anderson, C. W., and Graham, D. G. 1983. The effect of 3, 4-dimethyl substitution on the neurotoxicity of 2, 5-hexanedione. II. Dimethyl substitution accelerates pyrrole formation and protein crosslinking. Toxicol. Appl. Pharmacol. 71:372-382. (Pubitemid 14218619)
    • (1983) Toxicology and Applied Pharmacology , vol.71 , Issue.3 , pp. 372-382
    • Anthony, D.C.1    Boekelheide, K.2    Anderson, C.W.3    Graham, D.G.4
  • 5
    • 0040528369 scopus 로고
    • Metal complexes in organic synthesis. III. Preparation of 3-alkylpentane-2, 4-diones by alkylation of nickel bis-pentane-2, 4-dionato with alkyl halides
    • Boya, M., Marquet, J., Moreno-Mañas, M., and Prior, M. 1979. Metal complexes in organic synthesis. III. Preparation of 3-alkylpentane-2, 4-diones by alkylation of nickel bis-pentane-2, 4-dionato with alkyl halides. Anal. Quim. 75:920-926.
    • (1979) Anal. Quim. , vol.75 , pp. 920-926
    • Boya, M.1    Marquet, J.2    Moreno-Mañas, M.3    Prior, M.4
  • 6
    • 0020463441 scopus 로고
    • Bulk preparation of CNS cytoskeleton and the separation of individual neurofilament proteins by gel filtration: Dye-binding characteristics and amino acid compositions
    • DOI 10.1111/j.1471-4159.1982.tb12562.x
    • Chiu, F.-C. and Norton, W. T. 1982. Bulk preparation of CNS cytoskeleton and the separation of individual neurofilament by gel filtration: Dyebinding characteristics and amino acid compositions. J. Neurochem. 39:1252-1260. (Pubitemid 13220378)
    • (1982) Journal of Neurochemistry , vol.39 , Issue.5 , pp. 1252-1260
    • Chiu, F.C.1    Norton, W.T.2
  • 7
    • 0022994922 scopus 로고
    • Mechanisms of in vitro pyrrole adduct autoxidation in 2,5-hexanedione-treated protein
    • DeCaprio, A. P. 1986. Mechanisms of in vitro pyrrole adduct autoxidation in 2, 5-hexanedione-treated protein. Mol. Pharmacol. 30:452-458. (Pubitemid 17202423)
    • (1986) Molecular Pharmacology , vol.30 , Issue.5 , pp. 452-458
    • DeCaprio, A.P.1
  • 8
    • 0002022283 scopus 로고    scopus 로고
    • N-Hexane, metabolites, and derivatives
    • eds. P. S. Spencer, H. H. Schaumburg, and C. Ludolph, New York: Oxford University Press
    • DeCaprio, A. P. 2000. n-Hexane, metabolites, and derivatives. In Experimental and Clinical Neurotoxicology, eds. P. S. Spencer, H. H. Schaumburg, and C. Ludolph, pp. 633-648. New York: Oxford University Press.
    • (2000) Experimental and Clinical Neurotoxicology , pp. 633-648
    • DeCaprio, A.P.1
  • 9
    • 0023873976 scopus 로고
    • Comparative neurotoxicity and pyrrole-forming potential of 2,5-hexanedione and perdeuterio-2,5-hexanedione in the rat
    • DeCaprio, A. P., Briggs, R. G., Jackowski, S. J., and Kim, J. C. S. 1988. Comparative neurotoxicity and pyrrole-forming potential of 2, 5-hexanedioneand perdeuterio-2, 5-hexanedione in the rat. Toxicol. Appl. Pharmacol. 92:75-85. (Pubitemid 18049692)
    • (1988) Toxicology and Applied Pharmacology , vol.92 , Issue.1 , pp. 75-85
    • DeCaprio, A.P.1    Briggs, R.G.2    Jackowski, S.J.3    Kim, J.C.S.4
  • 10
    • 0026779534 scopus 로고
    • Limited and selective adduction of carboxyl-terminal lysines in the high molecular weight neurofilament proteins by 2, 5-hexanedione in vitro
    • DeCaprio, A. P. and Fowke, J. H. 1992. Limited and selective adduction of carboxyl-terminal lysines in the high molecular weight neurofilament proteins by 2, 5-hexanedione in vitro. Brain Res. 586:219-228.
    • (1992) Brain Res. , vol.586 , pp. 219-228
    • DeCaprio, A.P.1    Fowke, J.H.2
  • 11
    • 0023483391 scopus 로고
    • Mechanism of formation and quantitation of imines, pyrroles, and stable nonpyrrole adducts in 2,5-hexanedione-treated protein
    • DeCaprio, A. P., Jackowski, S. J., and Regan, K. A. 1987. Mechanism of formation and quantitation of imines, pyrroles, and stable nonpyrrole adducts in 2, 5-hexanedione-treated protein. Mol. Pharmacol. 32:542-548. (Pubitemid 18006157)
    • (1987) Molecular Pharmacology , vol.32 , Issue.4 , pp. 542-548
    • DeCaprio, A.P.1    Jackowski, S.J.2    Regan, K.A.3
  • 12
    • 0031194356 scopus 로고    scopus 로고
    • Regioselective binding of 2,5-hexanedione to high-molecular-weight rat neurofilament proteins in vitro
    • DOI 10.1006/taap.1997.8181
    • DeCaprio, A. P., Kinney, E. A., and Fowke, J. H. 1997. Regioselective binding of 2, 5-hexanedione to high-molecular-weight rat neurofilament proteins in vitro. Toxicol. Appl. Pharmacol. 145:211-217. (Pubitemid 27294785)
    • (1997) Toxicology and Applied Pharmacology , vol.145 , Issue.1 , pp. 211-217
    • Decaprio, A.P.1    Kinney, E.A.2    Fowke, J.H.3
  • 13
    • 0021821585 scopus 로고
    • Alterations in rat axonal cytoskeletal proteins induced by in vitro and in vivo 2,5-hexanedione exposure
    • DOI 10.1016/0041-008X(85)90287-X
    • DeCaprio, A. P., and O'Neill, E. A. 1985. Alterations in rat axonal cytoskeletal proteins induced by in vitro and in vivo 2, 5-hexanedione exposure. Toxicol. Appl. Pharmacol. 78:235-247. (Pubitemid 15081083)
    • (1985) Toxicology and Applied Pharmacology , vol.78 , Issue.2 , pp. 235-247
    • DeCaprio, A.P.1    O'Neill, E.A.2
  • 14
    • 0020384150 scopus 로고
    • Covalent binding of a neurotoxic n-hexane metabolite: Conversion of primary amines to substitute pyrrole adducts by 2,5-hexanedione
    • DOI 10.1016/0041-008X(82)90389-1
    • DeCaprio, A. P., Olajos, E. J., and Weber, P. 1982. Covalent binding of a neurotoxic n-hexane metabolite: Conversion of primary amines to substituted pyrrole derivatives by 2, 5-hexanedione. Toxicol. Appl. Pharmacol. 65:440-450. (Pubitemid 13223253)
    • (1982) Toxicology and Applied Pharmacology , vol.65 , Issue.3 , pp. 440-450
    • DeCaprio, A.P.1    Olajos, F.J.2    Weber, P.3
  • 15
    • 0023395604 scopus 로고
    • Determination of erythrocyte life span in F-344, Wistar, and Sprague-Dawley rats using a modification of the [3H]diisopropylfluorophosphate ([3H]DFP) method
    • Derelanko, M. J. 1987. Determination of erythrocyte life span in F-344, Wistar, and Sprague-Dawley rats using a modification of the [3H] diisopropylfluorophosphate ([3H]DFP) method. Toxicol. Sci. 9:271-276.
    • (1987) Toxicol. Sci. , vol.9 , pp. 271-276
    • Derelanko, M.J.1
  • 16
    • 0018689072 scopus 로고
    • Development of rat spinal cord. I. Weight and length with a method for rapid removal
    • deSousa, B. N., and Horrocks, L. P. 1979. Development of rat spinal cord. I. Weight and length with a method for rapid removal. Dev. Neurosci. 2:115-121.
    • (1979) Dev. Neurosci. , vol.2 , pp. 115-121
    • DeSousa, B.N.1    Horrocks, L.P.2
  • 17
    • 0023635286 scopus 로고
    • 4,5-Dihydroxy-2-hexanone: A new metabolite of N-hexane and of 2,5-hexanedione in rat urine
    • Fedtke, N., and Bolt, H. M. 1987. 4, 5-Dihydroxy-2-hexanone: A new metabolite of n-hexane and of 2, 5-hexanedione in rat urine. Biomed. Environ. Mass Spectrom. 14:563-572. (Pubitemid 18060764)
    • (1987) Biomedical and Environmental Mass Spectrometry , vol.14 , Issue.10 , pp. 563-572
    • Fedtke, N.1    Bolt, H.M.2
  • 18
    • 0011234707 scopus 로고
    • 1, 3, 4, 7-Substituted isoindoles and isoindolenines
    • Fletcher, H. 1966. 1, 3, 4, 7-Substituted isoindoles and isoindolenines. Tetrahedron 22:2481-2486.
    • (1966) Tetrahedron , vol.22 , pp. 2481-2486
    • Fletcher, H.1
  • 19
    • 0002033702 scopus 로고
    • The oxidation of monocyclic pyrroles
    • Gardini, G. P. 1973. The oxidation of monocyclic pyrroles. Adv. Heterocyclic Chem. 15:67-98.
    • (1973) Adv. Heterocyclic Chem. , vol.15 , pp. 67-98
    • Gardini, G.P.1
  • 21
    • 0023103401 scopus 로고
    • Evidence that pyrrole formation is a pathogenetic step in γ-diketone neuropathy
    • DOI 10.1016/0041-008X(87)90296-1
    • Genter, M. B., Szakál-Quin, G., Anderson, W., Anthony, D. C., and Graham, D. G. 1986. Evidence that pyrrole formation is a pathogenetic step in ?-diketone neuropathy. Toxicol. Appl. Pharmacol. 87:351-362. (Pubitemid 17019119)
    • (1987) Toxicology and Applied Pharmacology , vol.87 , Issue.2 , pp. 351-362
    • Genter, M.B.1    Szakal-Quin, G.2    Anderson, C.W.3
  • 22
    • 0019965407 scopus 로고
    • Studies of the molecular pathogenesis of hexane neuropathy. II. Evidence that pyrrole derivatization of lysyl residues leads to protein crosslinking
    • DOI 10.1016/0041-008X(82)90237-X
    • Graham, D. G., Anthony, D. C., Boekelheide, K., Maschmann, N. A., Richards, R. G., Wolfram, J. W., and Shaw, B. R. 1982. Studies of the molecular pathogenesis of hexane neuropathy. II. Evidence that pyrrole derivatization of lysyl residues leads to protein crosslinking. Toxicol. Appl. Pharmacol. 64:415-422. (Pubitemid 12019093)
    • (1982) Toxicology and Applied Pharmacology , vol.64 , Issue.3 , pp. 415-422
    • Graham, D.G.1    Anthony, D.C.2    Boekelheide, K.3
  • 26
    • 0034214171 scopus 로고    scopus 로고
    • γ-Diketone peripheral neuropathy. I. Quantitative morphometric analyses of axonal atrophy and swelling
    • DOI 10.1006/taap.2000.8937
    • Lehning, E. J., Jortner, B. S., Fox, J. H., Arezzo, J. C., Kitano, T.-A., and LoPachin, R. M. 2000. γ-Diketone peripheral neuropathy I. Quantitative morphometric analyses of axonal atrophy and swelling. Toxicol. Appl. Pharmacol. 165:127-140. (Pubitemid 30395362)
    • (2000) Toxicology and Applied Pharmacology , vol.165 , Issue.2 , pp. 127-140
    • Lehning, E.J.1    Jortner, B.S.2    Fox, J.H.3    Arezzo, J.C.4    Kitano, T.-A.5    Lopachin, R.M.6
  • 27
    • 4143089396 scopus 로고    scopus 로고
    • γ-Diketone neuropathy: Axon atrophy and the role of cytoskeletal protein adduction
    • DOI 10.1016/j.taap.2004.03.008, PII S0041008X04001656
    • LoPachin, R. M. and DeCaprio, A. P. 2004. γ-Diketone neuropathy: Axon atrophy and the role of cytoskeletal protein adduction. Toxicol. Appl. Pharmacol. 199:20-34. (Pubitemid 39099452)
    • (2004) Toxicology and Applied Pharmacology , vol.199 , Issue.1 , pp. 20-34
    • LoPachin, R.M.1    DeCaprio, A.P.2
  • 28
    • 26444512720 scopus 로고    scopus 로고
    • Protein adduct formation as a molecular mechanism in neurotoxicity
    • DOI 10.1093/toxsci/kfi197
    • LoPachin, R. M. and DeCaprio, A. P. 2005. Protein adduct formation as a molecular mechanism in neurotoxicity. Toxicol. Sci. 86:214-225. (Pubitemid 41418633)
    • (2005) Toxicological Sciences , vol.86 , Issue.2 , pp. 214-225
    • LoPachin, R.M.1    DeCaprio, A.P.2
  • 29
    • 13844253331 scopus 로고    scopus 로고
    • 2,5-Hexanedione-induced changes in the neurofilament subunit pools of rat peripheral nerve
    • DOI 10.1016/j.neuro.2004.09.007
    • LoPachin, R. M., He, D., and Reid, M. L. 2005. 2, 5-Hexanedione-induced changes in the neurofilament subunit pools of rat peripheral nerve. NeuroToxicology 26:229-240. (Pubitemid 40248441)
    • (2005) NeuroToxicology , vol.26 , Issue.2 , pp. 229-240
    • LoPachin, R.M.1    He, D.2    Reid, M.L.3
  • 30
    • 2942739141 scopus 로고    scopus 로고
    • 2,5-Hexanedione-induced changes in the monomeric neurofilament protein content of rat spinal cord fractions
    • DOI 10.1016/j.taap.2004.03.002, PII S0041008X04001498
    • LoPachin, R. M., He, D., Reid, M. L., and Opanashuk, L. A. 2004. 2, 5- Hexanedione-induced changes in the monomeric neurofilament protein content of rat spinal cord fractions. Toxicol. Appl. Pharmacol. 198:61-73. (Pubitemid 38789129)
    • (2004) Toxicology and Applied Pharmacology , vol.198 , Issue.1 , pp. 61-73
    • LoPachin, R.M.1    He, D.2    Reid, M.L.3    Opanashuk, L.A.4
  • 31
    • 0242677820 scopus 로고    scopus 로고
    • γ-Diketone central neuropathy: Quantitative morphometric analysis of axons in rat spinal cord white matter regions and nerve roots
    • DOI 10.1016/j.taap.2003.07.005
    • LoPachin, R. M., Jortner, B. S., Reid, M. L., and Das, S. 2003. γ-Diketone central neuropathy: Quantitative morphometric analysis of axons in rat spinal cord white matter regions and nerve roots. Toxicol. Appl. Pharmacol. 193:29-46. (Pubitemid 37373763)
    • (2003) Toxicology and Applied Pharmacology , vol.193 , Issue.1 , pp. 29-46
    • LoPachin, R.M.1    Jortner, B.S.2    Reid, M.L.3    Das, S.4
  • 32
    • 0036561862 scopus 로고    scopus 로고
    • Neurological evaluation of toxic axonopathies in rats: Acrylamide and 2,5-hexanedione
    • DOI 10.1016/S0161-813X(02)00003-7, PII S0161813X02000037
    • LoPachin, R. M., Ross, J. F., Reid, M. L., Das, S., Mansukhani, S., and Lehning, E. J. 2002. Neurological evaluation of toxic axonopathies in rats: Acrylamide and 2, 5-hexanedione. NeuroToxicology 23:95-110. (Pubitemid 36559702)
    • (2002) NeuroToxicology , vol.23 , Issue.1 , pp. 95-110
    • LoPachin, R.M.1    Ross, J.F.2    Reid, M.L.3    Das, S.4    Mansukhani, S.5    Lehning, E.J.6
  • 33
    • 0025351804 scopus 로고
    • Giant axonopathy characterized by intermediate location of axonal enlargements and acceleration of neurofilament transport
    • DOI 10.1016/0006-8993(90)90062-G
    • Monaco, S., Wongmongkolrit, T., Shearson, C. M., Patton, A., Schaetzle, B., Autilio-Gambetti, L., Gambetti, P., and Sayre, L. M. 1990. Giant axonopathy characterized by intermediate location of axonal enlargements and acceleration of neurofilament transport. Brain Res. 519:73-81. (Pubitemid 20199672)
    • (1990) Brain Research , vol.519 , Issue.1-2 , pp. 73-81
    • Monaco, S.1    Wongmongkolrit, T.2    Shearson, C.M.3    Patton, A.4    Schaetzle, B.5    Autilio-Gambetti, L.6    Gambetti, P.7    Sayre, L.M.8
  • 34
    • 0026748428 scopus 로고
    • The role of pyrrole formation in the alteration of neurofilament transport induced during exposure to 2, 5-hexanedione
    • Pyle, S. J., Amarnath, V., Graham, D. G., and Anthony, D. C. 1992. The role of pyrrole formation in the alteration of neurofilament transport induced during exposure to 2, 5-hexanedione. J. Neuropathol. Exp. Neurol. 51:451-458.
    • (1992) J. Neuropathol. Exp. Neurol. , vol.51 , pp. 451-458
    • Pyle, S.J.1    Amarnath, V.2    Graham, D.G.3    Anthony, D.C.4
  • 35
    • 0023154756 scopus 로고
    • dl-Versus meso-3,4-dimethyl-2,5-hexanedione: A morphometric study of the proximo-distal distribution of axonal swellings in the anterior root of the rat
    • DOI 10.1016/0041-008X(87)90297-3
    • Rosenberg, C. K., Genter, M. B., Szakal-Quin, G., Anthony, D. C., and Graham, D. G. 1986. dl- Versus meso-3, 4-Dimethyl-2, 5-hexanedione: A morphometric study of the proximo-distal distribution of axonal swellings in the anterior root of the rat. Toxicol. Appl. Pharmacol. 87:363-373. (Pubitemid 17019120)
    • (1987) Toxicology and Applied Pharmacology , vol.87 , Issue.2 , pp. 363-373
    • Rosenberg, C.K.1    Genter, M.B.2    Szakal-Quin, G.3
  • 36
    • 0032234413 scopus 로고    scopus 로고
    • Extensive phosphorylation and axonal transport of triton-soluble neurofilament subunits
    • Intermediate Filaments, eds. H. D. Herrmann and R. A. Harris, New York: Plenum Press
    • Shea, T. B., Jung, C., Yabe, J., Ma, D., and Fischer, I. 1998 Extensive phosphorylation and axonal transport of triton-soluble neurofilament subunits. In Sub-cellular Biochemistry, vol. 31, Intermediate Filaments, eds. H. D. Herrmann and R. A. Harris, pp. 527-561. New York: Plenum Press.
    • (1998) Sub-cellular Biochemistry , vol.31 , pp. 527-561
    • Shea, T.B.1    Jung, C.2    Yabe, J.3    Ma, D.4    Fischer, I.5
  • 37
    • 0018194601 scopus 로고
    • On the specific molecular configuration of neurotoxic aliphatic hexacarbon compounds causing central-peripheral distal axonopathy
    • Spencer, P. S., Bischoff, M. C., and Schaumburg, H. H. 1978. On the specific molecular configuration of neurotoxic aliphatic hexacarbon compounds causing central-peripheral distal axonopathy. Toxicol. App. Pharmacol. 44:17-28. (Pubitemid 8381299)
    • (1978) Toxicology and Applied Pharmacology , vol.44 , Issue.1 , pp. 17-28
    • Spencer, P.S.1    Bischoff, M.C.2    Schaumburg, H.H.3
  • 39
    • 0033571227 scopus 로고    scopus 로고
    • Axonal neurofilaments are nonessential elements of toxicant-induced reductions in fast axonal transport: Video-enhanced differential interference microscopy in peripheral nervous system axons
    • Stone, J. D., Peterson, A. P., Eyer, J., Oblak, T. G., and Sickles, D. W. 1999. Axonal neurofilaments are nonessential elements of toxicant-induced reductions in fast axonal transport: Video-enhanced differential interference microscopy in peripheral nervous system axons. Toxicol. Appl. Pharmacol. 161:50-58.
    • (1999) Toxicol. Appl. Pharmacol. , vol.161 , pp. 50-58
    • Stone, J.D.1    Peterson, A.P.2    Eyer, J.3    Oblak, T.G.4    Sickles, D.W.5
  • 40
    • 0035313072 scopus 로고    scopus 로고
    • Neurofilaments are nonessential to the pathogenesis of toxicant-induced axonal degeneration
    • Stone, J. D., Peterson, A. P., Eyer, J., Oblak, T. G., and Sickles, D. W. 2001. Neurofilaments are nonessential to the pathogenesis of toxicant-induced axonal degeneration. J. Neurosci. 21:2278-2287. (Pubitemid 32240526)
    • (2001) Journal of Neuroscience , vol.21 , Issue.7 , pp. 2278-2287
    • Stone, J.D.1    Peterson, A.P.2    Eyer, J.3    Oblak, T.G.4    Sickles, D.W.5
  • 41
    • 0033794203 scopus 로고    scopus 로고
    • Neurofilaments are non-essential elements of toxicant-induced reductions in fast axonal transport: Pulse labeling in CNS neurons
    • Stone, J. D., Peterson, A. P., Eyer, J., and Sickles, D. W. 2000. Neurofilaments are non-essential elements of toxicant-induced reductions in fast axonal transport: Pulse labeling in CNS neurons. NeuroToxicology 21:447-457.
    • (2000) NeuroToxicology , vol.21 , pp. 447-457
    • Stone, J.D.1    Peterson, A.P.2    Eyer, J.3    Sickles, D.W.4
  • 42
    • 38749101956 scopus 로고    scopus 로고
    • Changes of cytoskeletal proteins in nerve tissues and serum of rats treated with 2, 5-hexanedione
    • Wang, Q. S., Hou, L. Y., Zhang, C. L., Song, F. Y., and Xie, K. Q. 2008. Changes of cytoskeletal proteins in nerve tissues and serum of rats treated with 2, 5-hexanedione. Toxicology 244:166-178.
    • (2008) Toxicology , vol.244 , pp. 166-178
    • Wang, Q.S.1    Hou, L.Y.2    Zhang, C.L.3    Song, F.Y.4    Xie, K.Q.5
  • 43
    • 0035078694 scopus 로고    scopus 로고
    • Novel 2,5-hexanedione analogues. Substituent-induced control of the protein cross-linking potential and oxidation susceptibility of the resulting primary amine-derived pyrroles
    • DOI 10.1021/tx000169q
    • Xu, G. Z., Singh, M. P., Gopal, D., and Sayre, L. M. 2001. Novel 2, 5- hexanedione analogues. Substituent-induced control of the protein crosslinking potential and oxidation susceptibility of the resulting primary amine-derived pyrroles. Chem. Res. Toxicol. 14:264-274. (Pubitemid 32238486)
    • (2001) Chemical Research in Toxicology , vol.14 , Issue.3 , pp. 264-274
    • Xu, G.1    Singh, M.P.2    Gopal, D.3    Sayre, L.M.4
  • 44
    • 0035716873 scopus 로고    scopus 로고
    • Toxicokinetic interaction of 2,5-hexanedione and methyl ethyl ketone
    • Yu, R. C., Hattis, D., Landaw, E. M., and Froines, J. R. 2002. Toxicokinetic interaction of 2, 5-hexanedione and methyl ethyl ketone. Arch. Toxicol. 75:643-652. (Pubitemid 34151151)
    • (2002) Archives of Toxicology , vol.75 , Issue.11 , pp. 643-652
    • Yu, R.1    Hattis, D.2    Landaw, E.M.3    Froines, J.R.4
  • 45
    • 0028141716 scopus 로고
    • Formation and structure of cross-linking and monomeric pyrrole autoxidation products in 2,5-hexanedione-treated amino acids, peptides, and protein
    • DOI 10.1021/tx00040a011
    • Zhu, M., Spink, D. C., Yan, B., Bank, S., and DeCaprio, A. P. 1994. Formation and structure of crosslinking and monomeric pyrrole autoxidation products in 2, 5-hexanedione-treated amino acids, peptides, and protein. Chem. Res. Toxicol. 7:551-558. (Pubitemid 24232353)
    • (1994) Chemical Research in Toxicology , vol.7 , Issue.4 , pp. 551-558
    • Zhu, M.1    Spink, D.C.2    Yan, B.3    Bank, S.4    DeCaprio, A.P.5
  • 46
    • 0029047166 scopus 로고
    • Inhibition of 2, 5-hexanedione-induced covalent protein crosslinking by biological thiols: Chemical mechanisms and toxicological implications
    • Zhu, M., Spink, D. C., Yan, B., Bank, S., and DeCaprio, A. P. 1995. Inhibition of 2, 5-hexanedione-induced covalent protein crosslinking by biological thiols: Chemical mechanisms and toxicological implications. Chem. Res. Toxicol. 8:764-771.
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 764-771
    • Zhu, M.1    Spink, D.C.2    Yan, B.3    Bank, S.4    DeCaprio, A.P.5


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