Skin sensitization and possible groupings for 'read across' for rosin based substances

Regulatory Toxicology and Pharmacology

Volumn 54, Issue 3, 2009, Pages 234-241

  Illing, H P A ^a   Malmfors, T ^b   Rodenburg, L ^c  

^a PICS Sherwood   (United Kingdom)

^b Malmfors Consulting AB   (Sweden)

^c HARRPA   (Belgium)

Author keywords

Chemically modified rosins; Groupings for 'read across'; Skin sensitization studies

Indexed keywords

ACID ANHYDRIDE; FUMARIC ACID; GLYCEROL; MALEIC ANHYDRIDE; PENTAERYTHRITOL; POLYMER; RESIN; ROSIN;

ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; ESTERIFICATION; EUROPEAN UNION; IMMUNE RESPONSE; LOCAL LYMPH NODE ASSAY; PRIORITY JOURNAL; SKIN SENSITIZATION; SOLUBILITY;

ANIMALS; ESTERS; MICE; PINUS; RESINS, PLANT; SKIN IRRITANCY TESTS;

EID: 67650272430     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2009.04.006     Document Type: Article

References (17)

1. Barratt M.D., and Basketter D.A. Chemical aspects of contact hypersensitivity. In: Kimber I., and Maurer T. (Eds). Toxicology of Contact Hypersensitivity (1996), Taylor and Francis, London
2. Basketter D.A., Blackie L., Dearman R.J., Kimber I., Ryan C.A., Gerberick G.F., Harvey P., Evans P., White I.R., and Rycroft R.J.G. Use of the local lymph node assay for the estimation of relative contact allergenicity potential. Contact Dermatitis 42 (2000) 344-348
3. Basketter D.A., Andersen K.E., Liden C., vanLoveren H., Boman A., Kimber I., Alanko K., and Berggren E. Evaluation of skin sensitising potential by using the existing methods and consideration of relevancy for elicitation. Contact Dermatitis 52 (2005) 39-43
4. Botham P.A., Lees D., Illing H.P.A., and Malmfors T. On the sensitization potential of rosin and oxidised rosin. Regul. Toxicol. Pharmacol. 52 (2008) 257-263
5. Cavender, F.L., 2001. Aliphatic and alicyclic amines. In: Bingham, E., Cohrssen, B. Powell, C.H. (Eds.), Patty's Toxicology, fifth ed., vol. 4, John Wiley (Wiley Interscience), New York, pp. 683-616.
6. Directive 2004/73/EC, 2004. Commission Directive 2004/73. EEC of 29 April 2004 adapting to technical progress for the twenty ninth time. Council Directive 67/548/EEC on the approximation of laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. Official J. L152, 1-311.
7. European Chemicals Bureau, 2005. Manual of decisions for implementation of the sixth and seventh amendments to Directive 67/548/EEC on dangerous substances (Directives 79/831/EEC and 92/32/EEC). Non confidential version. Updated version of June 2005. EUR 205189 EN. European Communities, p. 155.
8. Gafvert, E., Shao, L.P., Karlberg, A.T., Nillson, J.L.G., 1995. Maleopimaric acid - a contact allergen in fumaric acid-modified rosin used for paper size. Nord. Pulp Pap. Res. J. 199 (2), 139-144.
9. Illing, H.P.A., 2003. Chemical information for the test substances used in the HARRPA mouse LLNA studies on skin sensitization. Report for HARRPA, Brussels dated 1 August 2003.
10. Kimber I., Basketter D.A., Butler M., Gamer A., Garrigue J.L., Gerberick G.F., Newsome C., Streiling W., and Vohr H.W. Classification of contact allergens according to potency: proposals. Food Chem. Toxicol. 41 (2003) 1799-1809
11. Lea L.J., Warbrick E.V., Dearman R.J., Kimber I., and Basketter D. The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay. Am. J. Contact Dermatitis 10 (1990) 213-218
12. Nillson A.M., Gafvert E., Nilsson J.L.G., and Karlberg A.T. Different physical forms of maleopimaric acid give different allergenic responses. Contact Dermatitis 46 (2002) 38-43
13. Regulation (EC) no. 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the registration, evaluation, authorisation and restriction of chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EEC and repealing Council regulation (EEC) no. 793/93 and Commission regulation (EC) no. 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/97/EEC, 93/105/EC, and 2000/21/EC. Corrected version. Official J. L136/3 of 29.5.2007, pp. 3-280.
14. Regulation EU no. 1272/2008 of the European Parliament and of Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EEC, and amending Regulation (EC) no. 1907/2006. Official J. L355, 1-1355.
15. Shao L.P., Gafvert E., Karlberg A.T., Nilsson U., and Nilsson J.L.G. The allergenicity of glycerol esters and other esters of rosin (colophony). Contact Dermatitis 28 (1993) 229-234
16. Soltes J., and Zinkel D.F. Chemistry of rosin. In: Zinkel D.F., and Russell J. (Eds). Naval Stores: Production, Chemistry, Utilisation (1989), Pulp Chemicals Association, New York
17. United Nations, 2007. Globally Harmonised System of Classification and Labelling of Chemicals, second revised ed. New York and Geneva, pp. 149-150.