-
1
-
-
0346328229
-
Opportunities in somatostatin research: Biological, chemical and therapeutic aspects
-
Weckbecker G, Lewis I, Albert R, Schmid HA, Hoyer D, Bruns C 2003 Opportunities in somatostatin research: biological, chemical and therapeutic aspects. Nat Rev Drug Discov 2:999-1017
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 999-1017
-
-
Weckbecker, G.1
Lewis, I.2
Albert, R.3
Schmid, H.A.4
Hoyer, D.5
Bruns, C.6
-
3
-
-
2642535412
-
Regulation and function of somatostatin receptors
-
Olias G, Viollet C, Kusserow H, Epelbaum J, Meyerhof W 2004 Regulation and function of somatostatin receptors. J Neurochem 89:1057-1091
-
(2004)
J Neurochem
, vol.89
, pp. 1057-1091
-
-
Olias, G.1
Viollet, C.2
Kusserow, H.3
Epelbaum, J.4
Meyerhof, W.5
-
4
-
-
0029786687
-
Molecular biology of somatostatin receptor subtypes
-
Patel YC, Greenwood M, Panetta R, Hukovic N, Grigorakis S, Robertson LA, Srikant CB 1996 Molecular biology of somatostatin receptor subtypes. Metabolism 45:31-38
-
(1996)
Metabolism
, vol.45
, pp. 31-38
-
-
Patel, Y.C.1
Greenwood, M.2
Panetta, R.3
Hukovic, N.4
Grigorakis, S.5
Robertson, L.A.6
Srikant, C.B.7
-
5
-
-
0027436310
-
Splice variant of the somatostatin receptor 2 subtype, somatostatin receptor 2B, couples to adenylyl cyclase
-
Reisine T, Kong H, Raynor K, Yano H, Takeda J, Yasuda K, Bell GI 1993 Splice variant of the somatostatin receptor 2 subtype, somatostatin receptor 2B, couples to adenylyl cyclase. Mol Pharmacol 44:1016-1020
-
(1993)
Mol Pharmacol
, vol.44
, pp. 1016-1020
-
-
Reisine, T.1
Kong, H.2
Raynor, K.3
Yano, H.4
Takeda, J.5
Yasuda, K.6
Bell, G.I.7
-
6
-
-
0026673028
-
Cloning and expression of a novel mouse somatostatin receptor (SSTR2B)
-
Vanetti M, Kouba M, Wang X, Vogt G, Hollt V 1992 Cloning and expression of a novel mouse somatostatin receptor (SSTR2B). FEBS Lett 311:290-294
-
(1992)
FEBS Lett
, vol.311
, pp. 290-294
-
-
Vanetti, M.1
Kouba, M.2
Wang, X.3
Vogt, G.4
Hollt, V.5
-
8
-
-
43749098064
-
Somatostatin, cortistatin and their receptors in tumours
-
Volante M, Rosas R, Allia E, Granata R, Baragli A, Muccioli G, Papotti M 2008 Somatostatin, cortistatin and their receptors in tumours. Mol Cell Endocrinol 286:219-229
-
(2008)
Mol Cell Endocrinol
, vol.286
, pp. 219-229
-
-
Volante, M.1
Rosas, R.2
Allia, E.3
Granata, R.4
Baragli, A.5
Muccioli, G.6
Papotti, M.7
-
9
-
-
43549104820
-
Are somatostatin and cortistatin two siblings in regulating endocrine secretions? In vitro work ahead
-
Gahete MD, Duran-Prado M, Luque RM, Martinez-Fuentes AJ, Vazquez-Martinez R, Malagon MM, Castano JP 2008 Are somatostatin and cortistatin two siblings in regulating endocrine secretions? In vitro work ahead. Mol Cell Endocrinol 286:128-134
-
(2008)
Mol Cell Endocrinol
, vol.286
, pp. 128-134
-
-
Gahete, M.D.1
Duran-Prado, M.2
Luque, R.M.3
Martinez-Fuentes, A.J.4
Vazquez-Martinez, R.5
Malagon, M.M.6
Castano, J.P.7
-
10
-
-
34047199656
-
Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses
-
Gonzalez-Rey E, Chorny A, Del Moral RG, Varela N, Delgado M 2007 Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses. Ann Rheum Dis 66:582-588
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 582-588
-
-
Gonzalez-Rey, E.1
Chorny, A.2
Del Moral, R.G.3
Varela, N.4
Delgado, M.5
-
11
-
-
43549110929
-
Emergence of cortistatin as a new immunomodulatory factor with therapeutic potential in immune disorders
-
Gonzalez-Rey E, Delgado M 2007 Emergence of cortistatin as a new immunomodulatory factor with therapeutic potential in immune disorders. Mol Cell Endocrinol 286:135-140
-
(2007)
Mol Cell Endocrinol
, vol.286
, pp. 135-140
-
-
Gonzalez-Rey, E.1
Delgado, M.2
-
12
-
-
27744609322
-
New SRIF analogs in the control of human pituitary adenomas: Perspectives
-
Jaquet P, Saveanu A, Barlier A 2005 New SRIF analogs in the control of human pituitary adenomas: perspectives. J Endocrinol Invest 28:14-18
-
(2005)
J Endocrinol Invest
, vol.28
, pp. 14-18
-
-
Jaquet, P.1
Saveanu, A.2
Barlier, A.3
-
13
-
-
33847747850
-
Quantitative analysis of somatostatin receptor subtype (SSTR1-5) gene expression levels in somatotropinomas and non-functioning pituitary adenomas
-
Taboada GF, Luque RM, Bastos W, Guimaraes RF, Marcondes JB, Chimelli LM, Fontes R, Mata PJ, Filho PN, Carvalho DP, Kineman RD, Gadelha MR 2007 Quantitative analysis of somatostatin receptor subtype (SSTR1-5) gene expression levels in somatotropinomas and non-functioning pituitary adenomas. Eur J Endocrinol 156:65-74
-
(2007)
Eur J Endocrinol
, vol.156
, pp. 65-74
-
-
Taboada, G.F.1
Luque, R.M.2
Bastos, W.3
Guimaraes, R.F.4
Marcondes, J.B.5
Chimelli, L.M.6
Fontes, R.7
Mata, P.J.8
Filho, P.N.9
Carvalho, D.P.10
Kineman, R.D.11
Gadelha, M.R.12
-
14
-
-
0030218924
-
Evidence that a novel somatostatin receptor couples to an inward rectifier potassium current in AtT-20 cells
-
Tallent M, Dichter MA, Reisine T 1996 Evidence that a novel somatostatin receptor couples to an inward rectifier potassium current in AtT-20 cells. Neuroscience 73:855-864
-
(1996)
Neuroscience
, vol.73
, pp. 855-864
-
-
Tallent, M.1
Dichter, M.A.2
Reisine, T.3
-
15
-
-
0027493822
-
Clinical pharmacokinetics of octreotide. Therapeutic applications in patients with pituitary tumours
-
Chanson P, Timsit J, Harris AG 1993 Clinical pharmacokinetics of octreotide. Therapeutic applications in patients with pituitary tumours. Clin Pharmacokinet 25:375-391
-
(1993)
Clin Pharmacokinet
, vol.25
, pp. 375-391
-
-
Chanson, P.1
Timsit, J.2
Harris, A.G.3
-
16
-
-
1642265607
-
Octreotide: An active agent in epithelial ovarian carcinoma?
-
Jones RH, Reubi JC, Millan D, Vasey P 2004 Octreotide: an active agent in epithelial ovarian carcinoma? Lancet Oncol 5:251-253
-
(2004)
Lancet Oncol
, vol.5
, pp. 251-253
-
-
Jones, R.H.1
Reubi, J.C.2
Millan, D.3
Vasey, P.4
-
17
-
-
17744399907
-
Bim-23244, a somatostatin receptor subtype 2-and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas
-
Saveanu A, Gunz G, Dufour H, Caron P, Fina F, Ouafik L, Culler MD, Moreau JP, Enjalbert A, Jaquet P 2001 Bim-23244, a somatostatin receptor subtype 2-and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas. J Clin Endocrinol Metab 86:140-145
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 140-145
-
-
Saveanu, A.1
Gunz, G.2
Dufour, H.3
Caron, P.4
Fina, F.5
Ouafik, L.6
Culler, M.D.7
Moreau, J.P.8
Enjalbert, A.9
Jaquet, P.10
-
19
-
-
28444478741
-
The expression of the pituitary growth hormone-releasing hormone receptor and its splice variants in normal and neoplastic human tissues
-
Havt A, Schally AV, Halmos G, Varga JL, Toller GL, Horvath JE, Szepeshazi K, Koster F, Kovitz K, Groot K, Zarandi M, Kanashiro CA 2005 The expression of the pituitary growth hormone-releasing hormone receptor and its splice variants in normal and neoplastic human tissues. Proc Natl Acad Sci USA 102:17424-17429
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17424-17429
-
-
Havt, A.1
Schally, A.V.2
Halmos, G.3
Varga, J.L.4
Toller, G.L.5
Horvath, J.E.6
Szepeshazi, K.7
Koster, F.8
Kovitz, K.9
Groot, K.10
Zarandi, M.11
Kanashiro, C.A.12
-
20
-
-
0034641750
-
Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancers
-
Rekasi Z, Czompoly T, Schally AV, Halmos G 2000 Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancers. Proc Natl Acad Sci USA 97:10561-10566
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10561-10566
-
-
Rekasi, Z.1
Czompoly, T.2
Schally, A.V.3
Halmos, G.4
-
21
-
-
4344572783
-
Update on human α1-adrenoceptor subtype signaling and genomic organization
-
Hawrylyshyn KA, Michelotti GA, Coge F, Guenin SP, Schwinn DA 2004 Update on human α1-adrenoceptor subtype signaling and genomic organization. Trends Pharmacol Sci 25:449-455
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 449-455
-
-
Hawrylyshyn, K.A.1
Michelotti, G.A.2
Coge, F.3
Guenin, S.P.4
Schwinn, D.A.5
-
22
-
-
0031807848
-
Coexpression of gastrin and gastrin receptors (CCK-B and ΔCCK-B) in gastrointestinal tumour cell lines
-
McWilliams DF, Watson SA, Crosbee DM, Michaeli D, Seth R 1998 Coexpression of gastrin and gastrin receptors (CCK-B and ΔCCK-B) in gastrointestinal tumour cell lines. Gut 42:795-798
-
(1998)
Gut
, vol.42
, pp. 795-798
-
-
McWilliams, D.F.1
Watson, S.A.2
Crosbee, D.M.3
Michaeli, D.4
Seth, R.5
-
23
-
-
0028153733
-
Expression of multiple somatostatin receptor genes in AtT-20 cells. Evidence for a novel somatostatin-28 selective receptor subtype
-
Patel YC, Panetta R, Escher E, Greenwood M, Srikant CB 1994 Expression of multiple somatostatin receptor genes in AtT-20 cells. Evidence for a novel somatostatin-28 selective receptor subtype. J Biol Chem 269:1506-1509
-
(1994)
J Biol Chem
, vol.269
, pp. 1506-1509
-
-
Patel, Y.C.1
Panetta, R.2
Escher, E.3
Greenwood, M.4
Srikant, C.B.5
-
24
-
-
33646793998
-
Identification of the somatostatin receptor subtypes (sst) mediating the divergent, stimulatory/inhibitory actions of somatostatin on growth hormone secretion
-
Luque RM, Duran-Prado M, Garcia-Navarro S, Gracia-Navarro F, Kineman RD, Malagon MM, Castano JP 2006 Identification of the somatostatin receptor subtypes (sst) mediating the divergent, stimulatory/inhibitory actions of somatostatin on growth hormone secretion. Endocrinology 147:2902-2908
-
(2006)
Endocrinology
, vol.147
, pp. 2902-2908
-
-
Luque, R.M.1
Duran-Prado, M.2
Garcia-Navarro, S.3
Gracia-Navarro, F.4
Kineman, R.D.5
Malagon, M.M.6
Castano, J.P.7
-
25
-
-
33845869338
-
Porcine somatostatin receptor 2 displays typical pharmacological sst2 features but unique dynamics of homodimerization and internalization
-
Duran-Prado M, Bucharles C, Gonzalez BJ, Vazquez-Martinez R, Martinez-Fuentes AJ, Garcia-Navarro S, Rhodes SJ, Vaudry H, Malagon MM, Castano JP 2007 Porcine somatostatin receptor 2 displays typical pharmacological sst2 features but unique dynamics of homodimerization and internalization. Endocrinology 148:411-421
-
(2007)
Endocrinology
, vol.148
, pp. 411-421
-
-
Duran-Prado, M.1
Bucharles, C.2
Gonzalez, B.J.3
Vazquez-Martinez, R.4
Martinez-Fuentes, A.J.5
Garcia-Navarro, S.6
Rhodes, S.J.7
Vaudry, H.8
Malagon, M.M.9
Castano, J.P.10
-
26
-
-
34247473542
-
Evaluation of reference genes for quantitative real-time PCR in Ostertagia ostertagi by the coefficient of variation and geNorm approach
-
Van Zeveren AM, Visser A, Hoorens PR, Vercruysse J, Claerebout E, Geldhof P 2007 Evaluation of reference genes for quantitative real-time PCR in Ostertagia ostertagi by the coefficient of variation and geNorm approach. Mol Biochem Parasitol 153:224-227
-
(2007)
Mol Biochem Parasitol
, vol.153
, pp. 224-227
-
-
Van Zeveren, A.M.1
Visser, A.2
Hoorens, P.R.3
Vercruysse, J.4
Claerebout, E.5
Geldhof, P.6
-
27
-
-
0032544633
-
The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling
-
Burstein ES, Spalding TA, Brann MR 1998 The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling. J Biol Chem 273:24322-24327
-
(1998)
J Biol Chem
, vol.273
, pp. 24322-24327
-
-
Burstein, E.S.1
Spalding, T.A.2
Brann, M.R.3
-
28
-
-
0034464742
-
Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
-
Gether U 2000 Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr Rev 21:90-113
-
(2000)
Endocr Rev
, vol.21
, pp. 90-113
-
-
Gether, U.1
-
29
-
-
42949108700
-
Cell-based assays in GPCR drug discovery
-
Siehler S 2008 Cell-based assays in GPCR drug discovery. Biotechnol J 3:471-483
-
(2008)
Biotechnol
, vol.J 3
, pp. 471-483
-
-
Siehler, S.1
-
30
-
-
33750323311
-
The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer
-
Takahashi K, Furukawa C, Takano A, Ishikawa N, Kato T, Hayama S, Suzuki C, Yasui W, Inai K, Sone S, Ito T, Nishimura H, Tsuchiya E, Nakamura Y, Daigo Y 2006 The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer. Cancer Res 66:9408-9419
-
(2006)
Cancer Res
, vol.66
, pp. 9408-9419
-
-
Takahashi, K.1
Furukawa, C.2
Takano, A.3
Ishikawa, N.4
Kato, T.5
Hayama, S.6
Suzuki, C.7
Yasui, W.8
Inai, K.9
Sone, S.10
Ito, T.11
Nishimura, H.12
Tsuchiya, E.13
Nakamura, Y.14
Daigo, Y.15
-
31
-
-
0036271475
-
Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis
-
Papotti M, Bongiovanni M, Volante M, Allia E, Landolfi S, Helboe L, Schindler M, Cole SL, Bussolati G 2002 Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis. Virchows Arch 440:461-475
-
(2002)
Virchows Arch
, vol.440
, pp. 461-475
-
-
Papotti, M.1
Bongiovanni, M.2
Volante, M.3
Allia, E.4
Landolfi, S.5
Helboe, L.6
Schindler, M.7
Cole, S.L.8
Bussolati, G.9
-
32
-
-
1942471034
-
Cortistatin production by HepG2 human hepatocellular carcinoma cell line and distribution of somatostatin receptors
-
Notas G, Kolios G, Mastrodimou N, Kampa M, Vasilaki A, Xidakis C, Castanas E, Thermos K, Kouroumalis E 2004 Cortistatin production by HepG2 human hepatocellular carcinoma cell line and distribution of somatostatin receptors. J Hepatol 40:792-798
-
(2004)
J Hepatol
, vol.40
, pp. 792-798
-
-
Notas, G.1
Kolios, G.2
Mastrodimou, N.3
Kampa, M.4
Vasilaki, A.5
Xidakis, C.6
Castanas, E.7
Thermos, K.8
Kouroumalis, E.9
-
33
-
-
0033762030
-
Subcellular distribution of somatostatin sst2A receptors in human tumors of the nervous and neuroendocrine systems: Membranous versus intracellular location
-
Reubi JC, Waser B, Liu Q, Laissue JA, Schonbrunn A 2000 Subcellular distribution of somatostatin sst2A receptors in human tumors of the nervous and neuroendocrine systems: membranous versus intracellular location. J Clin Endocrinol Metab 85:3882-3891
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3882-3891
-
-
Reubi, J.C.1
Waser, B.2
Liu, Q.3
Laissue, J.A.4
Schonbrunn, A.5
-
34
-
-
33646524968
-
Immunohistochemical distribution and subcellular localization of the somatostatin receptor subtype 1 (sst1) in the rat hypothalamus
-
Stroh T, Sarret P, Tannenbaum GS, Beaudet A 2006 Immunohistochemical distribution and subcellular localization of the somatostatin receptor subtype 1 (sst1) in the rat hypothalamus. Neurochem Res 31:247-257
-
(2006)
Neurochem Res
, vol.31
, pp. 247-257
-
-
Stroh, T.1
Sarret, P.2
Tannenbaum, G.S.3
Beaudet, A.4
-
35
-
-
23744461839
-
The Δe13 isoform of the calcitonin receptor forms a six-transmembrane domain receptor with dominant-negative effects on receptor surface expression and signaling
-
Baltimore, Md
-
Seck T, Pellegrini M, Florea AM, Grignoux V, Baron R, Mierke DF, Horne WC 2005 The Δe13 isoform of the calcitonin receptor forms a six-transmembrane domain receptor with dominant-negative effects on receptor surface expression and signaling. Mol Endocrinol (Baltimore, Md) 19:2132-2144
-
(2005)
Mol Endocrinol
, vol.19
, pp. 2132-2144
-
-
Seck, T.1
Pellegrini, M.2
Florea, A.M.3
Grignoux, V.4
Baron, R.5
Mierke, D.F.6
Horne, W.C.7
-
36
-
-
0033818629
-
Cortistatin: A member of the somatostatin neuropeptide family with distinct physiological functions
-
Spier AD, de Lecea L 2000 Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res Brain Res Rev 33:228-241
-
(2000)
Brain Res Brain Res Rev
, vol.33
, pp. 228-241
-
-
Spier, A.D.1
de Lecea, L.2
-
37
-
-
33645080443
-
Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia
-
Gonzalez-Rey E, Chorny A, Robledo G, Delgado M 2006 Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia. J Exp Med 203:563-571
-
(2006)
J Exp Med
, vol.203
, pp. 563-571
-
-
Gonzalez-Rey, E.1
Chorny, A.2
Robledo, G.3
Delgado, M.4
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