Various solvent systems for solubility enhancement of enrofloxacin

Indian Journal of Pharmaceutical Sciences

Volumn 71, Issue 1, 2009, Pages 82-87

  Seedher, Neelam ^a   Agarwal, Pooja ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Co solvents; Enrofloxacin; Sodium dodecylsulphate; Solubility; Surfactants

Indexed keywords

ALCOHOL; CETRIMIDE; DODECYL SULFATE SODIUM; ENROFLOXACIN; GLYCEROL; MACROGOL 400; MACROGOL 8000; POLYSORBATE 80; PROPYLENE GLYCOL; SODIUM HYDROXIDE;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DIELECTRIC CONSTANT; DRUG POTENTIATION; DRUG SOLUBILITY; IONIC STRENGTH; LIPOPHILICITY; PH; SOLVENT EFFECT;

EID: 67650233423     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.51958     Document Type: Article

References (11)

1. Elmas M, Trans B, Kaya S, Bas AL, Yazar E, Yarsan E. Pharmacokinetics of enrofoxacin after intravenous and intramuscular administration in angora goats. Can J Vet Res 2001;65:64-7.
2. Lizondo M, Pons M, Gallardo JE. Physicochemical properties of enrofoxacin. J Pharm Biomed Anal 1997;15:1845-9.
3. Zhao L, Li P, Yalkowsky SH. Solubilization of fuasterone. J Pharm Sci 1999;88:967-9.
4. Millard JW, Alvarez-Nunez FA, Yalkowsky SH. Solubilization by cosolvents. Establishing useful constants for the log-linear model. Int J Pharm 2002;245:153-66.
5. Strickley RG. Solubilizing excipients in oral and injectable formulations. Pharm Res 2004;21:201-30.
6. Saha RN, Sanjeev C, Priya KP, Sreekhar C, Shashikanth G. Solubility enhancement of nimesulide and ibuprofen by solid dispersion technique. Indian J Pharm Sci 2002;64:529-34.
7. Ran Y, Zhao L, Xu Q, Yalkowsky SH. Solubilization of cyclosporin A. AAPS Pharm Sci Tech 2002;2:2.
8. Seedher N, Bhatia S. Solubility enhancement of cox-2 inhibitors using various solvent systems. AAPS Pharm Sci Tech 2003;4:33.
9. Mall S, Buckton G, Rawlins DA. Dissolution behaviour of sulphonamides into sodium dodecyl sulphate micelles: A thermodynamic approach. J Pharm Sci 1996;85:75-8.
10. Rangel-Yagui CO, Pessoa A. Jr. Tavares LC. Micellar solubilization of drugs. J Pharm Sci 2005;8:147-63.
11. Torchilin VP. Structure and design of polymeric surfactant-based drug delivery systems. J Control Release 2001;73:137-72.