Oral administration of low doses of plant-based HBsAg induced antigen-specific IgAs and IgGs in mice, without increasing levels of regulatory T cells

Vaccine

Volumn 27, Issue 35, 2009, Pages 4798-4807

  Kostrzak, Anna ^a,b,c   Cervantes Gonzalez, Minerva ^a   Guetard, Denise ^a   Nagaraju, Devendra Bellary ^c,d   Wain Hobson, Simon ^a   Tepfer, David ^c   Pniewski, Tomasz ^b   Sala, Monica ^a  

^a CNRS   (France)

^b INSTITUTE OF PLANT GENETICS   (Poland)

^c CEMAGREF   (France)

^d GITAM UNIVERSITY   (India)

Author keywords

DNA immunization; HBV; Oral immunization; Oral tolerance; Plant based vaccine; Tregs

Indexed keywords

GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; TRANSCRIPTION FACTOR FOXP3;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DNA IMMUNIZATION; FEMALE; HEPATITIS B; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT LEAF; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TOBACCO; TRANSGENIC MOUSE; VACCINE PRODUCTION;

ADMINISTRATION, ORAL; ANIMALS; HEPATITIS B ANTIBODIES; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; MICE; PLANT LEAVES; PLANTS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS; T-LYMPHOCYTES, REGULATORY; TOBACCO; VACCINES, DNA;

EID: 67650232931     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.05.092     Document Type: Article

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