Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa

European Journal of Clinical Nutrition

Volumn 63, Issue 7, 2009, Pages 850-857

  Chhagan, M K ^a,d   Van den Broeck, J ^b   Luabeya, K K A ^a   Mpontshane, N ^c   Tucker, K L ^d   Bennish, M L ^e,f  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c Pharmaceutical Product Development   (United Kingdom)

^d TUFTS UNIVERSITY   (United States)

^e Tufts University ^*  (South Africa)

^f JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOL; TRACE ELEMENT; ZINC;

ARTICLE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DIET SUPPLEMENTATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MEGADOSE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; INFANT; INTERVENTION STUDY; MAJOR CLINICAL STUDY; MONOTHERAPY; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PREVALENCE; RANDOMIZED CONTROLLED TRIAL; RURAL AREA; SOUTH AFRICA; UNDERWEIGHT;

COHORT STUDIES; DIARRHEA, INFANTILE; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FERROUS COMPOUNDS; GLUCONATES; GROWTH DISORDERS; HIV INFECTIONS; HUMANS; INCIDENCE; INFANT; IRON; MICRONUTRIENTS; NUTRITION DISORDERS; RURAL POPULATION; SOUTH AFRICA; VITAMIN A; ZINC;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 67650225599     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2008.78     Document Type: Article

References (30)

1. Baqui AH, Zaman K, Persson LA, El Arifeen S, Yunus M, Begum N et al. (2003). Simultaneous weekly supplementation of iron and zinc is associated with lower morbidity due to diarrhea and acute lower respiratory infection in Bangladeshi infants. J Nutr 133, 4150-4157.
2. Bess Jr JW, Powell PJ, Issaq HJ, Schumack LJ, Grimes MK, Henderson LE et al. (1992). Tightly bound zinc in human immunodeficiency virus type 1, human T-cell leukemia virus type I, and other retroviruses. J Virol 66, 840-847.
3. Bhutta ZA, Bird SM, Black RE, Brown KH, Gardner JM, Hidayat A et al. (2000). Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: Pooled analysis of randomized controlled trials. Am J Clin Nutr 72, 1516-1522.
4. Bobat R, Coovadia H, Stephen C, Naidoo KL, McKerrow N, Black RE et al. (2005). Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: A randomised double-blind placebo-controlled trial. Lancet 366, 1862-1867.
5. Brown KH, Rivera JA, Bhutta Z, Gibson RS, King JC, Lonnerdal B et al. (2004). International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control. Food Nutr Bull 25 (Suppl 2), S99-S203.
6. Dijkhuizen MA, Wieringa FT, West CE, Muherdiyantiningsih, Muhilal (2001). Concurrent micronutrient deficiencies in lactating mothers and their infants in Indonesia. Am J Clin Nutr 73, 786-791.
7. Fawzi WW, Mbise R, Spiegelman D, Fataki M, Hertzmark E, Ndossi G (2000). Vitamin A supplements and diarrheal and respiratory tract infections among children in Dar es Salaam, Tanzania. J Pediatr 137, 660-667.
8. Garrib A, Jaffar S, Knight S, Bradshaw D, Bennish ML (2006). Rates and causes of child mortality in an area of high HIV prevalence in rural South Africa. Trop Med Int Health 11, 1841-1848.
9. Gupta DN, Mondal SK, Ghosh S, Rajendran K, Sur D, Manna B (2003). Impact of zinc supplementation on diarrhoeal morbidity in rural children of West Bengal, India. Acta Paediatr 92, 531-536.
10. Hamill PV, Drizd TA, Johnson CL, Reed RB, Roche AF, Moore WM (1979). Physical growth: National Center for Health Statistics percentiles. Am J Clin Nutr 32, 607-629.
11. Hoffman DJ, Lee SK (2005). The prevalence of wasting, but not stunting, has improved in the Democratic People's Republic of Korea. J Nutr 135, 452-456.
12. Labadarios D, Steyn NP, Maunder E, MacIntryre U, Gericke G, Swart R et al. (2005). The National Food Consumption Survey (NFCS): South Africa, 1999. Public Health Nutr 8, 533-543.
13. Long KZ, Rosado JL, Montoya Y, de Lourdes Solano M, Hertzmark E, DuPont HL et al. (2007). Effect of vitamin A and zinc supplementation on gastrointestinal parasitic infections among Mexican children. Pediatrics 120, e846-e855.
14. Long KZ, Santos JI, Rosado JL, Lopez-Saucedo C, Thompson-Bonilla R, Abonce M et al. (2006). Impact of vitamin A on selected gastrointestinal pathogen infections and associated diarrheal episodes among children in Mexico City, Mexico. J Infect Dis 194, 1217-1225.
15. Luabeya KK, Mpontshane N, Mackay M,Ward H, Elson I, Chhagan M et al. (2007). Zinc or multiple micronutrient supplementation to reduce diarrhea and respiratory disease in South African children: A randomized controlled trial. PLoS ONE 2, e541.
16. Nchito M, Friis H, Michaelsen KF, Mubila L, Olsen A (2006). Iron supplementation increases small intestine permeability in primary school children in Lusaka, Zambia. Trans R Soc Trop Med Hyg 100, 791-794.
17. Osendarp SJ, Santosham M, Black RE, Wahed MA, van Raaij JM, Fuchs GJ (2002). Effect of zinc supplementation between 1 and 6 mo of life on growth and morbidity of Bangladeshi infants in urban slums. Am J Clin Nutr 76, 1401-1408.
18. Papathakis PC, Rollins NC, Chantry CJ, Bennish ML, Brown KH (2007). Micronutrient status during lactation in HIV-infected and HIV-uninfected South African women during the first 6 mo after delivery. Am J Clin Nutr 85, 182-192.
19. Penny ME, Marin RM, Duran A, Peerson JM, Lanata CF, Lonnerdal B et al. (2004). Randomized controlled trial of the effect of daily supplementation with zinc or multiple micronutrients on the morbidity, growth, and micronutrient status of young Peruvian children. Am J Clin Nutr 79, 457-465.
20. Rahman MM, Vermund SH, Wahed MA, Fuchs GJ, Baqui AH, Alvarez JO (2001). Simultaneous zinc and vitamin A supplementation in Bangladeshi children: randomised double blind controlled trial. BMJ 323, 314-318.
21. Sazawal S, Black RE, Bhan MK, Jalla S, Sinha A, Bhandari N (1997). Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea - a community-based, double-blind, controlled trial. Am J Clin Nutr 66, 413-418.
22. Sempertegui F, Estrella B, Camaniero V, Betancourt V, Izurieta R, Ortiz W et al. (1999). The beneficial effects of weekly low-dose vitamin A supplementation on acute lower respiratory infections and diarrhea in Ecuadorian children. Pediatrics 104, e1.
23. Smuts CM, Dhansay MA, Faber M, van Stuijvenberg ME, Swanevelder S, Gross R et al. (2005a). Efficacy of multiple micronutrient supplementation for improving anemia, micronutrient status, and growth in South African infants. J Nutr 135, 653S-659S.
24. Smuts CM, Lombard CJ, Benade AJ, Dhansay MA, Berger J, Hop le T et al. (2005b). Efficacy of a foodlet-based multiple micronutrient supplement for preventing growth faltering, anemia, and micronutrient deficiency of infants: The four country IRIS trial pooled data analysis. J Nutr 135, 631S-638S.
25. Umeta M, West CE, Haidar J, Deurenberg P, Hautvast JG (2000). Zinc supplementation and stunted infants in Ethiopia: A randomised controlled trial. Lancet 355, 2021-2026.
26. Untoro J, Karyadi E, Wibowo L, Erhardt MW, Gross R (2005). Multiple micronutrient supplements improve micronutrient status and anemia but not growth and morbidity of Indonesian infants: A randomized, double-blind, placebo-controlled trial. J Nutr 135, 639S-645S.
27. Van den Broeck J, Mackay M, Mpontshane N, Kany Kany Luabeya A, Chhagan M, Bennish ML (2007). Maintaining data integrity in a rural clinical trial. Clin Trials 4, 572-582.
28. WHO (2005a). Technical updates of the guidelines on Integrated Management of Childhood Illness (IMCI): Evidence and recommendations for further adaptations. World Health Organization: Geneva.
29. WHO (2005b). World Health Organization global database on child growth and nutrition. http://www.who.int/nutgrowthdb/database/en/.
30. WHO (2007). The World Health Organization child growth standards. www.who.int/childgrowth/en/.