Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 15, 2009, Pages 4134-4138

  Kang, Iou Jiun ^a   Wang, Li Wen ^a   Hsu, Sheng Ju ^a   Lee, Chung Chi ^a   Lee, Yen Chun ^a   Wu, Yen Shian ^a   Hsu, Tsu An ^a   Yueh, Andrew ^a   Chao, Yu Sheng ^a   Chern, Jyh Haur ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

KCV inhibitors

Indexed keywords

2,3 DIHYDRO INDOLE DERIVATIVE; 3,4 DIHYDRO 2H QUINOLINE 1 CARBOTHIOIC ACID AMIDE DERIVATIVE; ANTIVIRUS AGENT; INDOLE DERIVATIVE; INDOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANTIVIRAL AGENTS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HEPACIVIRUS; HEPATITIS C; HUMANS; INDOLES; MODELS, CHEMICAL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PROTEIN STRUCTURE, TERTIARY; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 67650164756     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.06.009     Document Type: Article

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