Low molecular weight heparin in the treatment of severe acute pancreatitis: A multiple centre prospective clinical study

Asian Journal of Surgery

Volumn 32, Issue 2, 2009, Pages 89-94

  Xin Sheng, Lu ^a   Fu, Qiu ^a   Jie Qin, Li ^b   Qin Qiao, Fan ^c   Ri Guang, Zhou ^d   Yu Hang, Ai ^a   Kai Cheng, Zhang ^b   Yi Xiong, Li ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b No 163 Central Hospital of PLA   (China)

^c UNIVERSITY OF SOUTH CHINA   (China)

^d Central Hospital of Longgang District   (China)

Author keywords

Low molecular weight heparin; Prospective clinical study; Severe acute pancreatitis

Indexed keywords

EID: 67650103198     PISSN: 10159584     EISSN: 02193108     Source Type: Journal    
DOI: 10.1016/S1015-9584(09)60017-8     Document Type: Article

References (12)

1. Schneider L, Peitschmann M, Harcwig W, et al. Inosine reduces microcirculatory disturbance and inflammatory organ damage in experimental acute pancreatitis in rats. Am J Surg 2006;191:510-4.
2. Karne S, Gorelick FS. Etiopathogenesis of acute pancreatitis. Surg Clin North Amer 1999;79:699-710.
3. Renzuli P.Jacob SM, Tauber M, et al. Severe pancreatitis: case-oriented discussion of interdisciplinary management. Pancreatology 2005;5:145-156.
4. Qiu F, Lu XS, Huang YK. Effect of low molecular weight heparin on pancreatic microcirculation in severe acute pancreatitis in a rodent model. Chin Med J 2007;120:2260-3.
5. Pancreas Branch of Chinese Surgical Association. Criteria of the clinical diagnosis and classification of acute pancreatitis. Chinese J Surg 1997;35:773-5 [In Chinese].
6. Balthazar EJ. Acute pancreatitis: assessment of severity with clinical and CT evaluation. Radiology 2002;223:603-3.
7. Menza MA, Murraay GB. Pancreatic encephalopathy. Biol Psychiatry 1989;25:781-5.
8. Marshall JC, Cook DJ, Christon NV, et al. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med 1995;23:1638-52.
9. Norman JG, Fink GW, Yang G, et al. Tissue-specific cytokin production during experimental acute pancreatitis. A probable mechanism for distant organ disfunction. Dig Dis Sci 1997; 42:1783-8.
10. BhatiaM, Neoptolemos JP, SlavinJ. Inflammatory mediators as therapeutic targets in acute pancreatitis. Curr Opin Investig Drugs 2001;2:496-501.
11. Cuthbertson CM, Christophi C. Disturbance of the microvasculation in acute pancreatitis. Brit J Surg 2006;93:518-30.
12. Leizorovicz A, Simonnrau G, Decousus H, et al. Comparison of efficacy and safety of lower molecular weight heparins and unfractionated heparin in initial treatment of deep venous thrombosis: a meta-analysis. Brit Med J 1994;309:229-304.