Imaging considerations for in vivo 13C metabolic mapping using hyperpolarized 13C-pyruvate

Magnetic Resonance in Medicine

Volumn 62, Issue 1, 2009, Pages 1-10

  Yen, Yi Fen ^a   Kohler, S J ^b   Chen, A P ^c   Tropp, J ^a   Bok, R ^d   Wolber, J ^e   Albers, M J ^d,f   Gram, K A ^g   Zierhut, M L ^d,f   Park, I ^d,f   Zhang, V ^d,f   Hu, S ^d,f   Nelson, S J ^d,f   Vigneron, D B ^d,f   Kurhanewicz, J ^d,f   Dirven, H A A M ^g   Hurd, R E ^a  

^a GE HEALTHCARE   (United States)

^b UNION COLLEGE   (United States)

^c GE HEALTHCARE   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e GE HEALTHCARE   (United Kingdom)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g GE HEALTHCARE   (Norway)

Author keywords

3D spectroscopic imaging; EPSI; Hyperpolarized 13C; In vivo metabolism; Metabolic dynamics

Indexed keywords

AMINO ACIDS; CHEMICAL SHIFT; ENCODING (SYMBOLS); IMAGE ENHANCEMENT; IMAGE QUALITY; METABOLISM; SIGNAL ENCODING; SPIN POLARIZATION;

CHEMICAL SHIFT IMAGING; ECHO-PLANAR SPECTROSCOPIC IMAGING; EPSI; HYPERPOLARIZED; IN-VIVO; MATHEMATICAL SIMULATIONS; SAMPLING STRATEGIES; SPECTROSCOPIC IMAGING;

SIGNAL TO NOISE RATIO;

CARBON 13; PYRUVIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPUTER SIMULATION; CONTROLLED STUDY; ECHO PLANAR IMAGING; HYPERPOLARIZATION; IMAGE QUALITY; IN VIVO STUDY; MATHEMATICAL ANALYSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SIGNAL NOISE RATIO; THREE DIMENSIONAL IMAGING;

EID: 67650094011     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.21987     Document Type: Article

References (23)

1. 13C magnetic resonance imaging for in vivo tumor diagnosis. Cancer Res 2006;66:10855-10860.
2. 1. Acad Radiol 2006;13:932-942.
3. Golman K, in't Zandt R, Thaning M. Real-time metabolic imaging. Proc Natl Acad Sci USA 2006;103:11270-11275.
4. 13C-1-pyruvate. Magn Reson Med 2007;58:65-69.
5. Chen AP, Albers MJ, Cunningham CH, Kohler SJ, Yen YF, Hurd RE, Tropp J, Bok R, Pauly JM, Nelson SJ, Kurhanewicz J, Vigneron DB. Hyperpolarized C-13 spectroscopic imaging of the TRAMP mouse at 3T: initial experience. Magn Reson Med 2007;58:1099-1106.
6. 13C. J Magn Reson 2007;187:357-362.
7. 13C MRSI. In: Proceedings of the 15th Annual Meeting of ISMRM, Berlin, Germany, 2007 (Abstract 367).
8. Nelson SJ, Chen AP, Bok R, Albers MJ, Zierhut ML, Kurhanewicz J, Vigneron DB, Kohler SJ, Yen YF, Tropp J, Gram KA, Wolber J, Dirven H, Hurd RE. Hyperpolarized C-13 MRSI data of dog prostate at 3T. In: Proceedings of the 15th Annual Meeting of ISMRM, Berlin, Germany, 2007 (Abstract 536).
9. 13C imaging. In: Proceedings of the 15th Annual Meeting of ISMRM, Berlin, Germany, 2007 (Abstract 2928).
10. Ardenkjaer-Larsen JH, Fridlund B, Gram A, Hansson G, Hansson L, Lerche MH, Servin R, Thaning M, Golman K. Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR. Proc Natl Acad Sci USA 2003;100:10158-10163.
11. 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading. Cancer Res 2008;68:8607-8615.
12. 13C 3D-MRSI following therapy in a mouse model of prostate cancer. In: Proceedings of the 16th Annual Meeting of ISMRM, Toronto, Ontario, Canada, 2008 (Abstract 888).
13. 129Xe MR. J Magn Reson 1996;B113:179-183.
14. Mugler JP III. Optimization of gradient-echo sequences for hyperpolarized noble gas MRI. In: Proceedings of the 6th Annual Meeting of ISMRM, Sydney, Australia, 1998 (Abstract 1904).
15. 3He magnetic resonance microscopy of the lung. Magn Reson Med 2001;45:365-370.
16. 3He MRI: spatial resolution and signal-to-noise ratio considerations. Magn Reson Med 2002;47:687-695.
17. Svensson J, Petersson JS, Ståhlberg F, Larsson EM, Leander P, Olsson LE. Image artifacts due to a time-varying contrast medium concentration in 3D contrast-enhanced MRA. J Magn Reson Imaging 1999;10:919-928.
18. Mansfield P. Spatial mapping of the chemical shift in NMR. Magn Reson Med 1984;1:370-386.
19. 1H spectroscopic imaging in human brain by echo-planar spatial-spectral encoding. Magn Reson Med 1995;33:34-40.
20. Feinberg DA, Turner R, Jakab PD, von Kienlin M. Echo-planar imaging with asymmetric gradient modulation and inner-volume excitation. Magn Reson Med 1990;13:162-169.
21. Cunningham CH, Vigneron DB, Chen AP, Xu D, Nelson SJ, Hurd RE, Kelley DA, Pauly JM. Design of flyback echo-planar readout gradients for magnetic resonance spectroscopic imaging. Magn Reson Med 2005;54:1286-1289.
22. Derby K, Tropp J, Hawryszko C. Design and evaluation of a novel dual-tuned resonator for spectroscopic imaging. J Magn Reson 1990;86:645-651.
23. 1-pyruvate affect metabolic results in dog prostate? In: Proceedings of the 16th Annual Meeting of ISMRM, Toronto, Ontario, Canada, 2008 (Abstract 891).