Early brain swelling in acute hypoxia

Journal of Applied Physiology

Volumn 107, Issue 1, 2009, Pages 244-252

  Dubowitz, David J ^a   Dyer, Edward A W ^b,c   Theilmann, Rebecca J ^a   Buxton, Richard B ^a   Hopkins, Susan R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Arterial spin labeling; Cerebral blood flow; Cerebral blood volume; Cerebrospinal fluid volume; Magnetic resonance imaging

Indexed keywords

ACUTE DISEASE; ADULT; ALTITUDE DISEASE; ARTICLE; BRAIN BLOOD FLOW; BRAIN HYPOXIA; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SPIN LABELING; SWELLING; VOLUMETRY;

ACUTE DISEASE; ADULT; ALTITUDE SICKNESS; ANOXIA; BLOOD CIRCULATION TIME; BRAIN EDEMA; CEREBROVASCULAR CIRCULATION; FEMALE; HEMODYNAMICS; HUMANS; HYPOXIA, BRAIN; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; QUESTIONNAIRES; SELF-EXAMINATION;

EID: 67650092767     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.90349.2008     Document Type: Article

References (43)

1. Ainslie PN, Poulin MJ. Ventilatory, cerebrovascular, and cardiovascular interactions in acute hypoxia: regulation by carbon dioxide. J Appl Physiol 97: 149-159, 2004.
2. Basnyat B, Murdoch DR. High-altitude illness. Lancet 361: 1967-1974, 2003.
3. Baumgartner RW, Spyridopoulos I, Bartsch P, Maggiorini M, Oelz O. Acute mountain sickness is not related to cerebral blood flow: a decompression chamber study. J Appl Physiol 86: 1578-1582, 1999.
4. Berre J, Vachiery JL, Moraine JJ, Naeije R. Cerebral blood flow velocity responses to hypoxia in subjects who are susceptible to high-altitude pulmonary oedema. Eur J Appl Physiol Occup Physiol 80: 260-263, 1999.
5. Buck A, Schirlo C, Jasinksy V, Weber B, Burger C, von Schulthess GK, Koller EA, Pavlicek V. Changes of cerebral blood flow during short-term exposure to normobaric hypoxia. J Cereb Blood Flow Metab 18: 906-910, 1998.
6. Burrows G. On Disorders of the Cerebral Circulation and on the Connection Between Affections of the Brain and Diseases of the Heart. Philadelphia, PA: Lea & Blanchard, 1848.
7. Ding XQ, Finsterbusch J, Wittkugel O, Saager C, Goebell E, Fitting T, Grzyska U, Zeumer H, Fiehler J. Apparent diffusion coefficient, fractional anisotropy and T2 relaxation time measurement. Clin Neuroradiol 17: 230-238, 2007.
8. Dyer EA, Hopkins SR, Perthen JE, Buxton RB, Dubowitz DJ. Regional cerebral blood flow during acute hypoxia in individuals susceptible to acute mountain sickness. Respir Physiol Neurobiol 160: 267-276, 2008.
9. Francis ST, Pears JA, Butterworth S, Bowtell RW, Gowland PA. Measuring the change in CBV upon cortical activation with high temporal resolution using look-locker EPI and Gd-DTPA. Magn Reson Med 50: 483-492, 2003.
10. Grubb RL Jr, Raichle ME, Eichling JO, Ter-Pogossian MM. The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time. Stroke 5: 630-639, 1974.
11. Hackett PH, Roach RC. High-altitude illness. N Engl J Med 345: 107-114, 2001.
12. Hopkins SR, Garg J, Bolar DS, Balouch J, Levin DL. Pulmonary blood flow heterogeneity during hypoxia and high-altitude pulmonary edema. Am J Respir Crit Care Med 171: 83-87, 2005.
13. Ito H, Kanno I, Ibaraki M, Hatazawa J, Miura S. Changes in human cerebral blood flow and cerebral blood volume during hypercapnia and hypocapnia measured by positron emission tomography. J Cereb Blood Flow Metab 23: 665-670, 2003.
14. 15O-labeled carbon dioxide or water, carbon monoxide and oxygen: a multicentre study in Japan. Eur J Nucl Med 31: 635-643, 2004.
15. Jansen GF, Kagenaar DA, Basnyat B, Odoom JA. Basilar artery blood flow velocity and the ventilatory response to acute hypoxia in mountaineers. Respir Physiol Neurobiol 133: 65-74, 2002.
16. Jensen JB, Wright AD, Lassen NA, Harvey TC, Winterborn MH, Raichle ME, Bradwell AR. Cerebral blood flow in acute mountain sickness. J Appl Physiol 69: 430-433, 1990.
17. Jezzard P, Duewell S, Balaban RS. MR relaxation times in human brain: measurement at 4 T. Radiology 199: 773-779, 1996.
18. Jochimsen TH, Norris DG, Mildner T, Moller HE. Quantifying the intra- and extravascular contributions to spin-echo fMRI at 3 T. Magn Reson Med 52: 724-732, 2004.
19. Kellie G. An account of the appearances observed in the dissection of two of three individuals presumed to have perished in the storm of the 3rd, and whose bodies were discovered in the vicinity of Leith on the morning of the 4th of November 1821 with some reflections on the pathology of the brain. In: Trans Med Chir Sci Edinb 1: 84-169, 1824.
20. Lee RR, Abraham RA, Quinn CB. Dynamic physiologic changes in lumbar CSF volume quantitatively measured by three-dimensional fast spin-echo MRI. Spine 26: 1172-1178, 2001.
21. Leontiev O, Dubowitz DJ, Buxton RB. CBF/CMRO2 coupling measured with calibrated BOLD fMRI: sources of bias. Neuroimage 36: 1110-1122, 2007.
22. Liu TT, Behzadi Y, Restom K, Uludag K, Lu K, Buracas GT, Dubowitz DJ, Buxton RB. Caffeine alters the temporal dynamics of the visual BOLD response. Neuroimage 23: 1402-1413, 2004.
23. Lu H, Golay X, Pekar JJ, Van Zijl PC. Functional magnetic resonance imaging based on changes in vascular space occupancy. Magn Reson Med 50: 263-274, 2003.
24. McRae DL, Barnum AS. Occipitalization of the atlas. Am J Roentgenol Radium Ther Nucl Med 70: 23-46, 1953.
25. Mintun MA, Lundstrom BN, Snyder AZ, Vlassenko AG, Shulman GL, Raichle ME. Blood flow and oxygen delivery to human brain during functional activity: theoretical modeling and experimental data. Proc Natl Acad Sci USA 98: 6859-6864, 2001.
26. Monro A. Observations on the Structure and Functions of the Nervous System. Edinburgh: Creech & Johnson, 1783.
27. Pagani M, Ansjon R, Lind F, Uusijarvi J, Sumen G, Jonsson C, Salmaso D, Jacobsson H, Larsson SA. Effects of acute hypobaric hypoxia on regional cerebral blood flow distribution: a single photon emission computed tomography study in humans. Acta Physiol Scand 168: 377-383, 2000.
28. Parkes LM, Rashid W, Chard DT, Tofts PS. Normal cerebral perfusion measurements using arterial spin labeling: reproducibility, stability, and age and gender effects. Magn Reson Med 51: 736-743, 2004.
29. Roach RC, Bärtsch P, Oelz O, Hackett PH. The Lake Louise acute mountain sickness scoring system. In: Hypoxia and Mountain Medicine., edited by Sutton JR, Houston CS, and Coates G. Burlington, VT: Queen City Printers, 1993, p. 272-274.
30. Roach RC, Hackett PH. Frontiers of hypoxia research: acute mountain sickness. J Exp Biol 204: 3161-3170, 2001.
31. Rostrup E, Knudsen GM, Law I, Holm S, Larsson HB, Paulson OB. The relationship between cerebral blood flow and volume in humans. Neuroimage 24: 1-11, 2005.
32. Schneider M, Bernasch D, Weymann J, Holle R, Bartsch P. Acute mountain sickness: influence of susceptibility, preexposure, and ascent rate. Med Sci Sports Exerc 34: 1886-1891, 2002.
33. Shimojyo S, Scheinberg P, Kogure K, Reinmuth OM. The effects of graded hypoxia upon transient cerebral blood flow and oxygen consumption. Neurology 18: 127-133, 1968.
34. Shockley RP, LaManna JC. Determination of rat cerebral cortical blood volume changes by capillary mean transit time analysis during hypoxia, hypercapnia and hyperventilation. Brain Res 454: 170-178, 1988.
35. Silvennoinen MJ, Kettunen MI, Kauppinen RA. Effects of hematocrit and oxygen saturation level on blood spin-lattice relaxation. Magn Reson Med 49: 568-571, 2003.
36. Smith SM, Zhang Y, Jenkinson M, Chen J, Matthews PM, Federico A, De Stefano N. Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage 17: 479-489, 2002.
37. Theilmann RJ, Dyer EA, Hopkins SR, Buxton RB, Dubowitz DJ. Quantitation of brain tissue swelling using MRI (Abstract). Proc Int Soc Magn Res Med 1: 2092, 2007.
38. Tsekos NV, Zhang F, Merkle H, Nagayama M, Iadecola C, Kim SG. Quantitative measurements of cerebral blood flow in rats using the FAIR technique: correlation with previous iodoantipyrine autoradiographic studies. Magn Reson Med 39: 564-573, 1998.
39. Van Osta A, Moraine JJ, Melot C, Mairbaurl H, Maggiorini M, Naeije R. Effects of high altitude exposure on cerebral hemodynamics in normal subjects. Stroke 36: 557-560, 2005.
40. Walsh EG, Minematsu K, Leppo J, Moore SC. Radioactive microsphere validation of a volume localized continuous saturation perfusion measurement. Magn Reson Med 31: 147-153, 1994.
41. Wong EC, Buxton RB, Frank LR. Implementation of quantitative perfusion imaging techniques for functional brain mapping using pulsed arterial spin labeling. NMR Biomed 10: 237-249, 1997.
42. Yen YF, Field AS, Martin EM, Ari N, Burdette JH, Moody DM, Takahashi AM. Test-retest reproducibility of quantitative CBF measurements using FAIR perfusion MRI and acetazolamide challenge. Magn Reson Med 47: 921-928, 2002.
43. Zhou J, Wilson DA, Ulatowski JA, Traystman RJ, van Zijl PC. Two-compartment exchange model for perfusion quantification using arterial spin tagging. J Cereb Blood Flow Metab 21: 440-455, 2001.