'Click' D1 receptor agonists with a 5-HT1A receptor pharmacophore producing D2 receptor activity

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 14, 2009, Pages 4873-4880

  Zhang, Jing ^a   Zhang, Hai ^a   Cai, Wenxian ^a   Yu, Leiping ^a   Zhen, Xuechu ^a   Zhang, Ao ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Arylbenzazepine; Arylpiperazine; Click reaction; Dopamine receptor; Serotonin 5 HT1A receptor

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 3 METHYL 1 (3 METHYLPHENYL) 1H 3 BENZAZEPINE; BENZAZEPINE DERIVATIVE; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; DOPAMINE 2 RECEPTOR; QUINPIROLE; SEROTONIN; SEROTONIN 1A RECEPTOR;

ANIMAL CELL; ARTICLE; CHEMICAL REACTION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; RECEPTOR AFFINITY;

ANIMALS; BENZAZEPINES; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MOLECULAR STRUCTURE; PIPERAZINES; PROTEIN BINDING; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67650081409     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.06.019     Document Type: Article

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