Diabetic foot infection: Usefulness of SPECT/CT for 99mTc-HMPAO- labeled leukocyte imaging

Journal of Nuclear Medicine

Volumn 50, Issue 7, 2009, Pages 1042-1046

  Filippi, Luca ^a   Uccioli, Luigi ^b   Giurato, Laura ^b   Schillaci, Orazio ^b,c  

^a MAGGIORE HOSPITAL   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c NONE   (Italy)

Author keywords

Diabetic foot; Hybrid SPECT CT; Infection; Leukocytes

Indexed keywords

HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M;

ADULT; ARTICLE; BONE BIOPSY; CELL LABELING; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIABETIC FOOT; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; FEMALE; FOLLOW UP; HUMAN; IMAGE ANALYSIS; LEUKOCYTE; MALE; OSTEOMYELITIS; PRIORITY JOURNAL; RADIATION DOSE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOFT TISSUE INFECTION;

DIABETIC FOOT; FEMALE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TECHNETIUM TC 99M EXAMETAZIME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 67650081273     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.108.059493     Document Type: Article

References (15)

1. Lipsky BA, Berendt AR, Deery HG, et al. Diagnosis and treatment of diabetic foot infections. Plast Reconstr Surg. 2006;117(suppl):212S-238S.
2. Becker W. Imaging osteomyelitis and the diabetic foot. Q J Nucl Med. 1999;43:9-20.
3. Ledermann HP, Morrison WB, Schweitzer ME. MR imaging analysis of pedal osteomyelitis: distribution, patterns of spread, and frequency of associated ulceration and septic arthritis. Radiology. 2002;223:747-755.
4. Schweitzer ME, Morrison WB. MR imaging of the diabetic foot. Radiol Clin North Am. 2004;42:61-71.
5. Devillers A, Moisan A, Hennion F, Garin E, Poirier JY, Bourguet P. Contribution of technetium-99m hexamethylpropylene amine oxime labelled leucocyte scintigraphy to the diagnosis of diabetic foot infection. Eur J Nucl Med. 1998;25:132-138.
6. Schauwecker DS, Park HM, Burt RW, et al. Combined bone scintigraphy and indium-111 leukocyte scans in neuropathic foot disease. J Nucl Med. 1988;29:1651-1655.
7. Schillaci O, Danieli R, Manni C, Simonetti G. Is SPECT/CT with a hybrid camera useful to improve scintigraphic imaging interpretation? Nucl Med Commun. 2004;25:705-710.
8. Keidar Z, Israel O, Krausz Y. SPECT/CT in tumor imaging: technical aspects and clinical applications. Semin Nucl Med. 2003;33:205-218.
9. 99mTc-HMPAO labeled leukocyte scintigraphy for bone and joint infections. J Nucl Med. 2006;47:1908-1913.
10. O'Connor MK, Kemp BJ. Single-photon emission computed tomography/computed tomography: basic instrumentation and innovations. Semin Nucl Med. 2006;36:258-266.
11. 111In-labeled leukocyte scintigraphy for diagnosis of infection. J Nucl Med. 2006;47:587-594.
12. 18F-FDG PET/CT. J Nucl Med. 2005;46:444-449.
13. Mani R, Krentz AJ, Shearman CP. Diabetic foot amputation: the need for an objective assessment tool. Wounds. 2003;15:241-245.
14. Horger M, Eschmann SM, Pfannenberg C, et al. The value of SPET/CT in chronic osteomyelitis. Eur J Nucl Med Mol Imaging. 2003;30:1665-1673.
15. 99mTc-MDP bone scintigraphy. Diabetes Metab. 2002;28:485-490.