Synthesis and antibacterial activities of eperezolid analogs with glycinyl substitutions

Archiv der Pharmazie

Volumn 342, Issue 7, 2009, Pages 377-385

  Wang, Xiao Jun ^a   Wu, Ning ^a   Du, Guang Jian ^a   Zhao, Shuang Qi ^a   Yan, Ming ^a   Gu, Lian Quan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Antibacterial; Eperezolid analog; Glycinyl substitution; Oxazolidinone

Indexed keywords

ANTIINFECTIVE AGENT; EPEREZOLID DERIVATIVE; GLYCINE DERIVATIVE; LINEZOLID; N [[3 [3 FLUORO 4 [4 [2 (4 CHLOROBENZAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIE; N [[3 [3 FLUORO 4 [4 [2 (4 FLUOROBENZAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (4 FLUOROPHENYLSULFONAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (4 METHYLBENZAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (4 METHYLPHENYLSULFONAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (4 NITROBENZAMIDO)ACETYL]PIPERAZIN 1 YL PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (4 TERTBUTYLBENZAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (BENZOAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (FURAN 2 CARBOXAMIDO)ACETYL]PIPERAZIN 1 YL PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (PHENYLSULFONAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (THIOPHENE 2 CARBOXAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 (THIOPHENE 2 SULFONAMIDO)ACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 ACETAMIDOACETYL)PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [3 FLUORO 4 [4 [2 ISONICOTINAMIDOACETYL]PIPERAZIN 1 YL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [6 [4 [2 (4 METHYLBENZAMIDO0ACETYL]PIPERAZIN 1 YL]PYRIDINE 3 YL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [6 [4 [2 (4 NITROBENZAMIDO)ACETYL]PIPERAZIN 1 YL]PYRIDINE 3 YL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [6 [4 [2 (BENZAMIDO)ACETYL]PIPERAZIN 1 YL]PYRIDINE 3 YL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; GRAM POSITIVE BACTERIUM; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS EPIDERMIDIS;

ACETAMIDES; ANTI-BACTERIAL AGENTS; ENTEROCOCCUS FAECALIS; GRAM-POSITIVE BACTERIA; MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXAZOLIDINONES; SPECTROPHOTOMETRY, INFRARED; STAPHYLOCOCCUS EPIDERMIDIS; STATIC ELECTRICITY;

EID: 67650081009     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200800233     Document Type: Article

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