Knockdown of stromal interaction molecule 1 attenuates store-operated Ca2+ entry and Ca2+ responses to acute hypoxia in pulmonary arterial smooth muscle

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 297, Issue 1, 2009, Pages

  Lu, Wenju ^a   Wang, Jian ^a   Peng, Gongyong ^a   Shimoda, Larissa A ^a   Sylvester, J T ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Calcium signaling; Hypoxic pulmonary vasoconstriction; KCl; STIM2; TRPC1; Vascular smooth muscle

Indexed keywords

CALCIUM BINDING PROTEIN; CALCIUM ION; FURA 2; PROTEIN STIM1; PROTEIN STIM2; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL MEMBRANE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; HYPOXIC LUNG VASOCONSTRICTION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PULMONARY ARTERY; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

ACUTE DISEASE; ANIMALS; ANOXIA; BLOTTING, WESTERN; CALCIUM SIGNALING; CHLORIDES; FLUORESCENCE; FURA-2; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; INDOLES; MANGANESE COMPOUNDS; MEMBRANE GLYCOPROTEINS; MYOCYTES, SMOOTH MUSCLE; POTASSIUM CHLORIDE; PULMONARY ARTERY; RATS; RNA, MESSENGER; TIME FACTORS; TRPC CATION CHANNELS;

EID: 67650079717     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00063.2009     Document Type: Article

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