The two active sites of thermotoga maritima CheA dimers bind ATP with dramatically different affinities

Biochemistry

Volumn 48, Issue 27, 2009, Pages 6412-6422

  Eaton, Anna K ^a,b   Stewart, Richard C ^a  

^a University of Maryland   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ATP-BINDING SITE; AUTOPHOSPHORYLATION; BACTERIAL CELLS; CENTRAL COMPONENT; DIMERIC PROTEINS; ENVIRONMENTAL CUES; HIGH-AFFINITY SITES; HISTIDINE KINASE; HOMODIMERS; NUCLEOTIDE ANALOGUES; PHOSPHORYL GROUPS; PHOSPHORYLATION REACTIONS; PROKARYOTIC CELLS; SIDE CHAINS; SIGNAL TRANSDUCTION PATHWAYS; SINGLE SITES; THERMOTOGA MARITIMA; TRIPHOSPHATE;

BINDING ENERGY; FLUORESCENCE; NUCLEIC ACIDS; NUCLEOTIDES; OLIGOMERS; SIGNAL TRANSDUCTION;

BINDING SITES;

2'(3') O (2,4,6 TRINITROPHENYL)ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; CHEA KINASE; DIMER; HISTIDINE; HOMODIMER; MAGNESIUM; MONOMER; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; BACTERIAL CELL; BINDING AFFINITY; BINDING COMPETITION; CELL MOTION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME MECHANISM; FLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROKARYOTIC CELL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THERMOTOGA MARITIMA;

ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEINS; BINDING SITES; BINDING, COMPETITIVE; DIMERIZATION; PHOSPHORYLATION; PROTEIN KINASES; SPECTROMETRY, FLUORESCENCE; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS); PROKARYOTA; THERMOTOGA MARITIMA;

EID: 67650079187     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900474g     Document Type: Article

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