Cardiac dysfunction during exercise in uncomplicated type 2 diabetes

Medicine and Science in Sports and Exercise

Volumn 41, Issue 5, 2009, Pages 977-984

  Regensteiner, Judith G ^a,b,c   Bauer, Timothy A ^b,d   Reusch, Jane E B ^b,c,d   Quaife, Robert A ^a   Chen, Marcus Y ^a   Smith, Susan C ^b   Miller, Tyler M ^a,b   Groves, Bertron M ^a   Wolfel, Eugene E ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Hemodynamic; Myocardial perfusion; Peak oxygen consumption; Pulmonary capillary wedge pressure; Type 2 diabetes mellitus

Indexed keywords

METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M;

ADULT; ARTICLE; BODY WEIGHT; CARDIOPULMONARY EXERCISE TEST; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DIABETES MELLITUS; ECHOCARDIOGRAPHY; EXERCISE; FEMALE; HEART FUNCTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE MASS; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE PERFUSION; HEART OUTPUT; HEMODYNAMIC PARAMETERS; HUMAN; IMAGING SYSTEM; LUNG WEDGE PRESSURE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PREMENOPAUSE; PULMONARY ARTERY CATHETER; SCREENING TEST; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STATISTICAL SIGNIFICANCE;

ADULT; CARDIAC OUTPUT, LOW; DIABETES MELLITUS, TYPE 2; EXERCISE; FEMALE; HEART FUNCTION TESTS; HEMODYNAMICS; HUMANS; MIDDLE AGED; OXYGEN CONSUMPTION; PERFUSION; PULMONARY WEDGE PRESSURE;

EID: 67650077670     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e3181942051     Document Type: Article

References (36)

1. Ahmed SS, Jaferi GA, Narang RM, Regan TJ. Preclinical abnormality of left ventricular function in diabetes mellitus. Am Heart J. 1975;89(2):153-8.
2. Baldi JC, Aoina JL, Whalley GA, et al. The effect of type 2 diabetes on diastolic function. Med Sci Sports Exerc. 2006;38(8): 1384-8.
3. Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation. 2007;115(25):3213-23.
4. Cerqueira MD, Weissman NJ, Dilsizian V, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation. 2002;105(4):539-42.
5. Christian TF, Rettmann DW, Aletras AH, et al. Absolute myocardial perfusion in canines measured by using dual-bolus first-pass MR imaging. Radiology. 2004;232(3):677-84.
6. Conway J, Lund-Johansen P. Thermodilution method for measuring cardiac output. Eur Heart J. 1990;11(Suppl I):17-20.
7. Di Bonito P, Moio N, Cavuto L, et al. Early detection of diabetic cardiomyopathy: usefulness of tissue Doppler imaging. Diabet Med. 2005;22(12):1720-5.
8. Fang ZY, Yuda S, Anderson V, Short L, Case C, Marwick TH. Echocardiographic detection of early diabetic myocardial disease. J Am Coll Cardiol. 2003;41(4):611-7.
9. Feustel PJ, Perkins RJ, Oppenlander JE, Stratton HH, Cohen IL. Feasibility of continuous oxygen delivery and cardiac output measurement by application of the Fick principle. Am J Respir Crit Care Med. 1994;149(3 Pt 1):751-8.
10. Ha JW, Lee HC, Kang ES, et al. Abnormal left ventricular longitudinal functional reserve in patients with diabetes mellitus: implication for detecting subclinical myocardial dysfunction using exercise tissue Doppler echocardiography. Heart. 2007;93(12): 1571-6.
11. Ha JW, Oh JK, Pellikka PA, et al. Diastolic stress echocardiog-raphy: a novel noninvasive diagnostic test for diastolic dysfunction using supine bicycle exercise Doppler echocardiography. J Am Soc Echocardiogr. 2005;18(1):63-8.
12. Henry WL, DeMaria A, Gramiak R, et al. Report of the American Society of Echocardiography Committee on nomenclature and standards in two-dimensional echocardiography. Circulation. 1980;62(2):212-7.
13. Higginbotham MB, Morris KG, Williams RS, McHale PA, Coleman RE, Cobb FR. Regulation of stroke volume during submaximal and maximal upright exercise in normal man. Circ Res. 1986;58(2):281-91.
14. Kelley DE, He J, Menshikova EV, Ritov VB. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes. 2002;51(10):2944-50.
15. Kitzman DW, Higginbotham MB, Cobb FR, Sheikh KH, Sullivan MJ. Exercise intolerance in patients with heart failure and preserved left ventricular systolic function: failure of the Frank- Starling mechanism. J Am Coll Cardiol. 1991;17(5):1065-72.
16. Kjaer M, Hollenbeck CB, Frey-Hewitt B, Galbo H, Haskell W, Reaven GM. Glucoregulation and hormonal responses to maximal exercise in non-insulin-dependent diabetes. J Appl Physiol. 1990;68(5):2067-74.
17. Kusunoki K, Nomura M, Kageyama N, et al. Detection of coronary arterial microvascular disorders using (99m)Tc-tetrofosmin uptake increase during exercise and coronary blood flow velocity patterns obtained by magnetic resonance imaging. Heart Vessels. 2004;19(1):1-7.
18. Lavoie JM, Dionne N, Helie R, Brisson GR. Menstrual cycle phase dissociation of blood glucose homeostasis during exercise. J Appl Physiol. 1987;62(3):1084-9.
19. MacRury SM, Small M, MacCuish AC, Lowe GD. Association of hypertension with blood viscosity in diabetes. Diabet Med. 1988;5(9):830-4.
20. McMillan DE. Exercise and diabetic microangiopathy. Diabetes. 1979;28(Suppl 1):103-6.
21. Moir S, Hanekom L, Fang ZY, et al. Relationship between myocardial perfusion and dysfunction in diabetic cardiomyopathy: a study of quantitative contrast echocardiography and strain rate imaging. Heart. 2006;92(10):1414-9.
22. Mustonen JN, Uusitupa MI, Tahvanainen K, et al. Impaired left ventricular systolic function during exercise in middle-aged insulin-dependent and noninsulin-dependent diabetic subjects without clinically evident cardiovascular disease. Am J Cardiol. 1988;62(17):1273-9.
23. Poirier P, Bogaty P, Garneau C, Marois L, Dumesnil JG. Diastolic dysfunction in normotensive men with well-controlled type 2 diabetes: importance of maneuvers in echocardiographic screening for preclinical diabetic cardiomyopathy. Diabetes Care. 2001;24(1): 5-10.
24. Quinones MA, Otto CM, Stoddard M, Waggoner A, Zoghbi WA. Recommendations for quantification of Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. J Am Soc Echocardiogr. 2002;15(2):167-84.
25. Regensteiner JG, Bauer TA, Reusch JE. Rosiglitazone improves exercise capacity in individuals with type 2 diabetes. Diabetes Care. 2005;28(12):2877-83.
26. Regensteiner JG, Bauer TA, Reusch JE, et al. Abnormal oxygen uptake kinetic responses in women with type II diabetes mellitus. J Appl Physiol. 1998;85(1):310-7.
27. Regensteiner JG, Hiatt WR, Byyny RL, Pickett CK, Woodard WD, Moore LG. Short-term effects of estrogen and progestin on blood pressure of normotensive postmenopausal women. J Clin Pharmacol. 1991;31(6):543-8.
28. Regensteiner JG, Sippel J, McFarling ET, Wolfel EE, Hiatt WR. Effects of non-insulin-dependent diabetes on oxygen consumption during treadmill exercise. Med Sci Sports Exerc. 1995;27(5): 661-7.
29. Roy TM, Peterson HR, Snider HL, et al. Autonomic influence on cardiovascular performance in diabetic subjects. Am J Med. 1989;87(4):382-8.
30. Rubler S, Dlugash J, Yuceoglu YZ, Kumral T, Branwood AW, Grishman A. New type of cardiomyopathy associated with diabetic glomerulosclerosis. Am J Cardiol. 1972;30(6):595-602.
31. Sanderson JE, Brown DJ, Rivellese A, Kohner E. Diabetic cardiomyopathy? An echocardiographic study of young diabetics. Br Med J. 1978;1(6110):404-7.
32. Schneider SH, Amorosa LF, Khachadurian AK, Ruderman NB. Studies on the mechanism of improved glucose control during regular exercise in type 2 (non-insulin-dependent) diabetes. Diabetologia. 1984;26(5):355-60.
33. Storto G, Cirillo P, Vicario ML, et al. Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: comparison with the results of intracoronary Doppler technique. J Nucl Cardiol. 2004;11(6):682-8.
34. Sugihara H, Yonekura Y, Kataoka K, Fukai D, Kitamura N, Taniguchi Y. Estimation of coronary flow reserve with the use of dynamic planar and SPECT images of Tc-99m tetrofosmin. J Nucl Cardiol. 2001;8(5):575-9.
35. Taylor BC, Sheffer DB. Understanding techniques for measuring cardiac output. Biomed Instrum Technol. 1990;24(3):188-97.
36. Wong CY, O'Moore-Sullivan T, Fang ZY, Haluska B, Leano R, Marwick TH. Myocardial and vascular dysfunction and exercise capacity in the metabolic syndrome. Am J Cardiol. 2005; 96(12):1686-91.