Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis

Neurology

Volumn 72, Issue 22, 2009, Pages 1965-

  Markovic Plese, S ^a   Jewells, V ^a   Speer, D ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; BETA1A INTERFERON; PLACEBO; SIMVASTATIN;

CLINICAL TRIAL; DISEASE ACTIVITY; HUMAN; LETTER; MULTIPLE SCLEROSIS; PRIORITY JOURNAL;

EID: 67650073013     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/01.wnl.0000349667.27301.c8     Document Type: Letter

References (7)

1. G Birnbaum B Cree I Altafullah M Zinser AT Reder Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis Neurology 71 2008 1390 1395
2. V Jewells D Speer Y Chen Statin and intramuscular interferon beta-1a combination therapy is safe and well tolerated in patients with clinically isolated syndrome suggestive of multiple sclerosis: a pilot study Mult Scler 13 2007 S270
3. S Markovic-Plese AK Singh I Singh Therapeutic potential of statins in multiple sclerosis: immune modulation, neuroprotection and neurorepair Future Neurol 3 2008 153 167
4. PS Sorensen JL Frederiksen J Lycke Does simvastatin antagonize the effect of interferon beta? Interim safety analysis of the ongoing SIMCOMBIN study Mult Scler 3 2007 S7 S273
5. R Rudick A Pace M Panzara Effects of statins on intramuscular interferon beta-1a for relapsing-remitting multiple sclerosis Mult Scler 13 2007 S7 S273
6. P Friedmann O Aktas S Waiczies High-dose atorvastatin alone or in combination with interferon-beta (IFN-beta) in the treatment of relapsing-remitting multiple sclerosis (RR-MS) Neurology 70 suppl 1 2008 P02.145
7. G Orefice M Quarantelli P Salvatore Interferon beta-1a and atorvastatin combination therapy: 12-month results from an open-label, randomized, clinical study Neurology 70 suppl 1 2008 P02.139