Intermittent hypoxia: Keeping it real

Journal of Applied Physiology

Volumn 107, Issue 1, 2009, Pages 1-3

  Morgan, Barbara J ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTERIAL OXYGEN SATURATION; BLOOD PRESSURE; DEOXYGENATION; EDITORIAL; HUMAN; HYPOXIA; INSPIRATORY CAPACITY; LUNG VENTILATION; NONHUMAN; PRIORITY JOURNAL; REOXYGENATION; SLEEP APNEA SYNDROME;

ANIMALS; ANOXIA; BLOOD GAS ANALYSIS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; MODELS, CARDIOVASCULAR; OXYGEN CONSUMPTION; SLEEP APNEA, OBSTRUCTIVE;

EID: 67650047762     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00304.2009     Document Type: Editorial

References (23)

1. Allahdadi KJ, Cherng TW, Pai H, Silva AQ, Walker BR, Nelin LD, Kanagy NL. Endothelin type A receptor antagonist normalizes blood pressure in rats exposed to eucapnic intermittent hypoxia. Am J Physiol Heart Circ Physiol 295: H434-H440, 2008.
2. Brooks D, Horner RL, Kozar LF, Render-Teixeira CL, Phillipson EA. Obstructive sleep apnea as a cause of systemic hypertension. Evidence from a canine model. J Clin Invest 99: 106-109, 1997.
3. Choi JB, Loredo JS, Norman D, Mills PJ, ncoli-Israel S, Ziegler MG, Dimsdale JE. Does obstructive sleep apnea increase hematocrit? Sleep Breath 10: 155-160, 2006.
4. Fletcher EC, Lesske J, Qian W, Miller CC, III, Unger T. Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats. Hypertension 19: 555-561, 1992.
5. Hinojosa-Laborde C, Mifflin SW. Sex differences in blood pressure response to intermittent hypoxia in rats. Hypertension 46: 1016-1021, 2005.
6. Hornbein TF, Griffo ZJ, Roos A. Quantitation of chemoreceptor activity: interrelation of hypoxia and hypercapnia. J Neurophysiol 24: 561-568, 1961.
7. Kanagy NL, Walker BR, Nelin LD. Role of endothelin in intermittent hypoxia-induced hypertension. Hypertension 37: 511-515, 2001.
8. Katragadda S, Xie A, Puleo D, Skatrud JB, Morgan BJ. Neural mechanism of the pressor response to obstructive and nonobstructive apnea. J Appl Physiol 83: 2048-2054, 1997.
9. Kraiczi H, Magga J, Sun XY, Ruskoaho H, Zhao X, Hedner J. Hypoxic pressor response, cardiac size, and natriuretic peptides are modified by long-term intermittent hypoxia. J Appl Physiol 87: 2025-2031, 1999.
10. Lee EJ, Woodske ME, Zou B, O'Donnell CP. Dynamic arterial blood gas analysis in conscious, unrestrained C57BL/6J mice during exposure to intermittent hypoxia. J Appl Physiol; doi:10.1152/japplphysiol.91255. 2008.
11. Lesske J, Fletcher EC, Bao G, Unger T. Hypertension caused by chronic intermittent hypoxia-influence of chemoreceptors and sympathetic nervous system. J Hypertens 15: 1593-1603, 1997.
12. Marcus NJ, Olson EB Jr, Bird CE, Philippi NR, Morgan BJ. Time-dependent adaptation in the hemodynamic response to hypoxia. Respir Physiol Neurobiol 165: 90-96, 2009.
13. Morgan BJ, Crabtree DC, Puleo DS, Badr MS, Toiber F, Skatrud JB. Neurocirculatory consequences of abrupt change in sleep state in humans. J Appl Physiol 80: 1627-1636, 1996.
14. Morgan BJ, Dempsey JA, Pegelow DF, Jacques A, Finn L, Palta M, Skatrud JB, Young TB. Blood pressure perturbations caused by subclinical sleep-disordered breathing. Sleep 21: 737-746, 1998.
15. Morgan BJ, Denahan T, Ebert TJ. Neurocirculatory consequences of negative intrathoracic pressure vs. asphyxia during voluntary apnea. J Appl Physiol 74: 2969-2975, 1993.
16. Narkiewicz K, van de Borne PJ, Pesek CA, Dyken ME, Montano N, Somers VK. Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea. Circulation 99: 1183-1189, 1999.
17. O'Connor GT, Caffo B, Newman AB, Quan SF, Rapoport DM, Redline S, Resnick HE, Samet J, Shahar E. Prospective study of sleep-disordered breathing and hypertension: the Sleep Heart Health Study. Am J Respir Crit Care Med. In press.
18. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 342: 1378-1384, 2000.
19. Tahawi Z, Orolinova N, Joshua IG, Bader M, Fletcher EC. Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats. J Appl Physiol 90: 2007-2013, 2001.
20. Tamisier R, Gilmartin GS, Launois SH, Pepin JL, Nespoulet H, Thomas RJ, Levy P, Weiss JW. A new model of chronic intermittent hypoxia in humans: effect on ventilation, sleep, and blood pressure. J Appl Physiol; doi:10.1152/japplphysiol.91165.2008.
21. Troncoso Brindeiro CM, da Silva AQ, Allahdadi KJ, Youngblood V, Kanagy NL. Reactive oxygen species contribute to sleep apnea-induced hypertension in rats. Am J Physiol Heart Circ Physiol 293: H2971-H2976, 2007.
22. Wang D, Grunstein RR, Teichtahl H. Association between ventilatory response to hypercapnia and obstructive sleep apnea-hypopnea index in asymptomatic subjects. Sleep Breath 11: 103-108, 2007.
23. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328: 1230-1235, 1993.