Ionic liquids as superior solvents for headspace gas chromatography of residual solvents with very low vapor pressure, relevant for pharmaceutical final dosage forms

Journal of Chromatography A

Volumn 1216, Issue 32, 2009, Pages 6020-6023

  Laus, Gerhard ^a   Andre, Max ^b   Bentivoglio, Gino ^a   Schottenberger, Herwig ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

GC MS; Headspace; Ionic liquid; Residual solvent

Indexed keywords

CARBOXY METHYLCELLULOSE; CORN STARCH; DIMETHYL PHOSPHATES; DOSAGE FORMS; GC-MS; HEADSPACE; HEADSPACE GAS; HEADSPACE GAS CHROMATOGRAPHY; LIMITS OF DETECTION; LIMITS OF QUANTIFICATION; LOW VAPOR PRESSURES; MAGNESIUM STEARATE; MATRIX; N-METHYLPYRROLIDONE; PHARMACEUTICAL PRODUCTS; REAL SAMPLES; RESIDUAL SOLVENT; RESIDUAL SOLVENTS; SULFOLANE; TETRALIN;

AROMATIC HYDROCARBONS; CHROMATOGRAPHIC ANALYSIS; ETHYLENE; ETHYLENE GLYCOL; GAS CHROMATOGRAPHY; HYDROSTATIC PRESSURE; IONIZATION OF LIQUIDS; IONS; MAGNESIUM; SOLVENTS; TERNARY SYSTEMS; VAPOR PRESSURE; VAPORS;

IONIC LIQUIDS;

1 METHYL 2 PYRROLIDINONE; BIOCEF; CARBOXYMETHYLCELLULOSE; CEFPODOXIME PROXETIL; DIMETHYL SULFOXIDE; ETHYLENE GLYCOL; GUAR GUM; IONIC LIQUID; MAGNESIUM STEARATE; STARCH; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; GAS CHROMATOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TABLET FORMULATION; VAPOR PRESSURE;

CEFTIZOXIME; EXCIPIENTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IMIDAZOLES; IONIC LIQUIDS; ORGANOPHOSPHORUS COMPOUNDS; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLVENTS; THIOPHENES; VAPOR PRESSURE;

CYAMOPSIS TETRAGONOLOBA; ZEA MAYS;

EID: 67650021902     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.06.036     Document Type: Article

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