Comparative effects of chlormadinone acetate and its 3α- and 3β-hydroxy metabolites on progesterone, androgen and glucocorticoid receptors

Pharmacology

Volumn 84, Issue 2, 2009, Pages 74-81

  Schneider, J ^a   Kneip, C ^a   Jahnel, U ^a  

^a GRÜNENTHAL GMBH   (Germany)

Author keywords

Androgenic activity; Binding affinity; Chlormadinone acetate; Glucocorticoid activity; Metabolites; Progestins; Progestomimetic activity; Steroid receptors

Indexed keywords

3ALPHA HYDROXYCHLORMADINONE ACETATE; 3BETA HYDROXYCHLORMADINONE ACETATE; ANDROGEN RECEPTOR; CHLORMADINONE ACETATE; DEXAMETHASONE; ESTRADIOL; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE ACETATE; METRIBOLONE; PROGESTERONE RECEPTOR; PROMEGESTONE; TESTOSTERONE; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; HORMONE ACTION; HUMAN; HUMAN CELL; MALE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROSTATE; RABBIT; RAT; SEMINAL VESICLE; THYMUS;

ANDROGEN ANTAGONISTS; ANIMALS; CELL PROLIFERATION; CHLORMADINONE ACETATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOMETRIUM; FEMALE; HUMANS; MALE; PROTEIN BINDING; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, ANDROGEN; RECEPTORS, GLUCOCORTICOID; RECEPTORS, PROGESTERONE;

EID: 67649998353     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000226601     Document Type: Article

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