Coagulation and fibrinolysis related cytokine imbalance in preeclampsia: The role of placental trophoblasts

Journal of Perinatal Medicine

Volumn 37, Issue 4, 2009, Pages 343-348

  Teng, Yin Cheng ^a   Lin, Qi De ^b   Lin, Jian Hua ^b   Ding, Chuan Wei ^b   Zuo, Ye ^b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cytokines; Hypercoagulability; Preeclampsia

Indexed keywords

CYTOKINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 10; INTERLEUKIN 12; MESSENGER RNA; PLACENTA PROTEIN 5; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBOPLASTIN; TISSUE FACTOR PATHWAY INHIBITOR; TISSUE PLASMINOGEN ACTIVATOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BLOOD CLOTTING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBRINOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERCOAGULABILITY; HYPOXIA; PLACENTA; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS; REPERFUSION; TROPHOBLAST;

ADULT; ANOXIA; CELLS, CULTURED; CYTOKINES; FEMALE; FIBRINOLYSIS; HUMANS; LIPOPROTEINS; PLACENTA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PRE-ECLAMPSIA; PREGNANCY; RNA, MESSENGER; THROMBOPLASTIN; TISSUE PLASMINOGEN ACTIVATOR; TROPHOBLASTS; YOUNG ADULT;

EID: 67649995055     PISSN: 03005577     EISSN: 16193997     Source Type: Journal    
DOI: 10.1515/JPM.2009.060     Document Type: Article

References (25)

1. ACOG Committee on Obstetric Practice. ACOG practice bulletin. Diagnosis and management of pre-eclampsia and eclampsia. Number 33, January 2002. American College of Obstetrics and Gynecologists. Int J Gynecol Obstet. 2002;77:67-75.
2. Aharon A, Brenner B, Katz T, Miyagi Y, Lanir N. Tissue factor and tissue factor pathway inhibitor levels in trophoblast cells: implications for placental hemostasis. Thromb Haemost. 2004;92:776-86.
3. Anteby EY, Greenfield C, Natanson-Yaron S, Goldman-Wohl D, Hamani Y, Khudyak V, et al. Vascular endothelial growth factor, epidermal growth factor and fibroblast factor -4 and -10 stimulate trophoblast plasminogen activator system and metalloproteinase-9. Mol Hum Reprod. 2004;10:229-35.
4. Bellart J, Gilabert R, Angles A, Piera V, Miralles RM, Monasterio J, et al. Tissue factor levels and high ratio of fibrinopeptide A:D-dimer as a measure of endothelial procoagulant disorder in pre-eclampsia. Br J Obstet Gynaecol. 1999;106:594-7.
5. Belo L, Santos-Silva A, Rumley A, Lowe G, Pereira-Leite L, Quintanilha A, et al. Elevated tissue plasminogen activator as a potential marker of endothelial dysfunction in pre-eclampsia: correlation with proteinuris. BIOG. 2002; 109:1250-5.
6. Burton J, Mashiah R, Cohen-Sacher B, Hod M, Orvieto R, Ben-Rafael Z, et al. Effect of thrombophylaxis on uterine and fetal circulation in pregnant women with a history of pregnancy complications. Thromb Res. 2002;102:235-41.
7. Bü tzow R, Virtanen I, Seppä lä M, Närvä nen O, Stenman UH, Ristimäki A, et al. Monoclonal antibodies reacting with placental protein 5: use in radioimmunoassay, Western blot analysis, and immunohistochemistry. J Lab Clin Med. 1988;111:249-56.
8. Edstrom CS, Calhoun DA, Christensen RD. Expression of tissue factor pathway inhibitor in human fetal and placental tissues. Early Hum Dev. 2000;59:77-84.
9. Feng Q, Liu K, Liu YX, Byrne S, Ockleford CD. Plasminogen activators and inhibitors are transcribed during early macaque implantation. Placenta. 2001;22:186-99.
10. Gao M, Nakabayashi M, Sakura M, Takeda Y. The imbalance of plasminogen activators and inhibitor in pre-eclampsia. J Obstet Gynaecol Res. 1996;22:9-16.
11. Huang ZF, Higuchi D, Lasky N, Broze GJ Jr. Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice. Blood. 1997;90:944-51.
12. Iino M, Foster DC, Kisiel W. Quantification and characterization of human endothelial cell-derived tissue factor pathway inhibitor-2. Arterioscler Thromb Vasc Biol. 1998; 18:40-6.
13. Isermann B, Sood R, Pawlinski R, Zogg M, Kalloway S, Degen JL, et al. The thrombomodulin-protein C system is essential for the maintenance of pregnancy. Nat Med. 2003;9:331-7.
14. Kadyrov M, Kingdom JC, Huppertz B. Divergent trophoblast invasion and apoptosis in placental bed spiral arteries from pregnancies complicated by maternal anemia and early onset pre-eclampsia/intrauterine growth restriction. Am J Obstet Gynecol. 2006;194:557-63.
15. Kwaan HC, Wang J, Boggio L, Weiss I, Grobman WA. The thrombogenic effect of an inflammatory cytokine on tro-phoblasts from women with pre-eclampsia. Am J Obstet Gynecol. 2004;191:2142-7.
16. Lanir N, Aharon A, Brenner B. Haemostastic mechanisms in human placenta. Best Pract Res Cl Ha. 2003;16:183-95.
17. Lash GE, Otun HA, Innes BA, Kirkley M, De Oliveira L, Searle RF, et al. Interferon-γ inhibits extravillous trophoblast cell invasion by a mechanism that involves both changes in apoptosis and protease levels. FASEB J. 2006;20:2512-8.
18. Many A, Schreiber L, Rosner S, Lessing JB, Eldor A, Kupferminc MJ. Pathologic features of the placenta in women with severe pregnancy complications and thrombophilia. Obstet Gynecol. 2001;98:1041-4.
19. Mello G, Parretti E, Marozio L, Pizzi C, Lojacono A, Frusca T, et al. Thrombophilia is significantly associated with severe pre-eclampsia. Hypertension. 2005;46:1270-4.
20. Neale D, Caze R, Small M, Krikun G, Mor G. First trimester trophoblast exposed to the sera of women with pre-eclampsia have increased secretion of tissue factor. Am J Obstet Gynecol. 2005;193:S13.
21. Petersen LC, Sprecher CA, Foster DC, Blumberg H, Hamamoto T, Kisiel W. Inhibitory properties of a novel human Kunitz-type protease inhibitor homologous to tissue factor pathway inhibitor. Biochemistry. 1996;35:266-72.
22. Sartori MT, Serena A, Saggiorato G, Campei S, Faggian D, Pagnan A, et al. Variations in fibrinolytic parameters and inhibin-A in pregnancy: related hypertensive disorders. J Thromb Haemost. 2008;6:352-8.
23. Solovey A, Kollander R, Shet A, Milbauer LC, Choong S, Panoskaltsis-Mortari A, et al. Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/ reoxygenation and inhibited by lovastatin. Blood. 2004; 104:840-6.
24. Ueyama M, Kasatori N, Urayama T, Maemura T, Yao Y, Shiraishi T, et al. Quantitative evaluation of the influence of ovarian steroids on plasminogen activators and inhibitors in human endometrial cells and trophoblasts. Thromb Res. 2002;25:235-44.
25. Wiwanitkit V. Correlation between plasminogen activator inhibitor-1 4G/5G polymorphism and pre-eclampsia: an appraisal. Arch Gynecol Obstet. 2006;273:322-4.