Simultaneous LC-MS analysis and of wogonin and oroxylin a in rat plasma, and pharmacokinetic studies after administration of the active fraction from xiao-xu-ming decoction

Chromatographia

Volumn 69, Issue 11-12, 2009, Pages 1259-1266

  Du, Kehe ^a,b   Wu, Caisheng ^a   Ding, Chunguang ^a   Zhao, Shanlin ^b   Qin, Hailin ^a   Zhang, Jinlan ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b LIAONING SHIHUA UNIVERSITY   (China)

Author keywords

Active fraction; Column liquid chromatography mass spectrometry; Oroxylin a; Pharmacokinetics; Wogonin; Xiao xu ming decoction

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETONITRILE; CHINESE DRUG; DIAZEPAM; FORMIC ACID; OROXYLIN A; UNCLASSIFIED DRUG; WOGONIN; XIAO XU MING;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG IDENTIFICATION; ELECTROSPRAY MASS SPECTROMETRY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETER; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION PROCESS;

EID: 67649992563     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1365/s10337-009-1072-5     Document Type: Article

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