Interplay between the heterotrimeric G-protein subunits Gαq and Gαi2 sets the threshold for chemotaxis and TCR activation

BMC Immunology

Volumn 10, Issue , 2009, Pages

  Ngai, Jacob ^a   Inngjerdingen, Marit ^a   Berge, Torunn ^a   Taskén, Kjetil ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CHEMOKINE RECEPTOR CXCR4; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA I2 SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA Q SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP 1; STROMAL CELL DERIVED FACTOR 1; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; CXCR4 PROTEIN, HUMAN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN KINASE LCK; PTPN6 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; CALCIUM CELL LEVEL; CHEMOTAXIS; CONTROLLED STUDY; DESENSITIZATION; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE MIGRATION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; CYTOLOGY; DRUG ANTAGONISM; FEEDBACK SYSTEM; GENETICS; IMMUNOLOGY; LEUKEMIA CELL LINE; METABOLISM;

CHEMOKINE CXCL12; CHEMOTAXIS; FEEDBACK, BIOCHEMICAL; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, CXCR4; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 67649987070     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-10-27     Document Type: Article

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