Acute myeloid leukemia with MYC amplification in the homogeneous staining regions and double minutes

Cancer Genetics and Cytogenetics

Volumn 192, Issue 2, 2009, Pages 96-98

  Lee, Seungok ^a   Kim, Myungshin ^a   Lim, Jihyang ^a   Kim, Yonggoo ^a   Han, Kyungja ^a   Kim, Hee Je ^b   Cho, Seok Goo ^b   Min, Woo Sung ^b  

^a The Catholic University of Korea   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CD33 ANTIGEN; CD34 ANTIGEN; ENOCITABINE; GEMTUZUMAB OZOGAMICIN; IDARUBICIN; MICROSOMAL AMINOPEPTIDASE; MYC PROTEIN; MYELOPEROXIDASE;

ACUTE GRANULOCYTIC LEUKEMIA; AGED; BLAST CELL; BONE MARROW BIOPSY; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CHROMOSOME 8Q; CLINICAL FEATURE; CYTOGENETICS; DOUBLE MINUTE CHROMOSOME; DRUG RESPONSE; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GENE AMPLIFICATION; GENE REARRANGEMENT; HUMAN; IMMUNOPHENOTYPING; LETTER; LEUKEMIA REMISSION; LEUKOCYTOSIS; MULTIPLE CYCLE TREATMENT; ONCOGENE MYC; PRIORITY JOURNAL; SURVIVAL TIME; WEAKNESS;

AGED; CHROMOSOME BANDING; CHROMOSOMES, HUMAN; FEMALE; GENE AMPLIFICATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, MYELOID, ACUTE; METAPHASE; PROTO-ONCOGENE PROTEINS C-MYC; STAINING AND LABELING;

EID: 67649980672     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2009.04.003     Document Type: Letter

References (9)

1. Rodon N., Solé F., Espinet B., Salido M., Zamora L., Cigudosa J.C., Woessner S., and Florensa L. A new case of acute nonlymphocytic leukemia (French-American-British subtype M1) with double minutes and c-MYC amplification. Cancer Genet Cytogenet 132 (2002) 161-164
2. Thomas L., Stamberg J., Gojo I., Ning Y., and Rapoport A.P. Double minute chromosomes in monoblastic (M5) and myeloblastic (M2) acute myeloid leukemia: two case reports and a review of literature. Am J Hematol 77 (2004) 55-61
3. Chudoba I., Hickmann G., Friedrich T., Jauch A., Kozlowski P., and Senger G. mBAND: a high resolution multicolor banding technique for the detection of complex intrachromosomal aberrations. Cytogenet Genome Res 104 (2004) 390-393
4. Herry A., Douet-Guilbert N., Guéganic N., Morel F., Le Bris M.J., Berthou C., and De Braekeleer M. Del(5q) and MLL amplification in homogeneously staining region in acute myeloblastic leukemia: a recurrent cytogenetic association. Ann Hematol 85 (2006) 244-249
5. Reddy K.S. Double minutes (dmin) and homogeneously staining regions (hsr) in myeloid disorders: a new case suggesting that dmin form hsr in vivo. Cytogenet Genome Res 119 (2007) 53-59
6. Moreau L.A., McGrady P., London W.B., Shimada H., Cohn S.L., Maris J.M., Diller L., Look A.T., and George R.E. Does MYCN amplification manifested as homogeneously staining regions at diagnosis predict a worse outcome in children with neuroblastoma? A Children's Oncology Group study. Clin Cancer Res 12 (2006) 5693-5697
7. Storlazzi C.T., Fioretos T., Surace C., Lonoce A., Mastrorilli A., Strömbeck B., D'Addabbo P., Iacovelli F., Minervini C., Aventin A., Dastugue N., Fonatsch C., Hagemeijer A., Jotterand M., Mühlematter D., Lafage-Pochitaloff M., Nguyen-Khac F., Schoch C., Slovak M.L., Smith A., Solè F., Van Roy N., Johansson B., and Rocchi M. MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene. Hum Mol Genet 15 (2006) 933-942
8. Bruckert P., Kappler R., Scherthan H., Link H., Hagmann F., and Zankl H. Double minutes and c-MYC amplification in acute myelogenous leukemia: Are they prognostic factors?. Cancer Genet Cytogenet 120 (2000) 73-79
9. Christacos N.C., Sherman L., Roy A., DeAngelo D.J., and Dal Cin P. Is the cryptic interstitial deletion of 8q24 surrounding MYC a common mechanism in the formation of double minute chromosome?. Cancer Genet Cytogenet 161 (2005) 90-92