Synthesis and biological evaluation of amide derivatives of diflunisal as potential anti-tumor agents

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 15, 2009, Pages 4399-4402

  Zhong, Guang Xiang ^a   Chen, Lu Lu ^a   Li, Hai Bo ^b   Liu, Fu Jin ^a   Hu, Jin Qing ^a   Hu, Wei Xiao ^a  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b Nantong Center for Disease Control and Prevention   (China)

Author keywords

Anti tumor agent; Biological evaluation; Diflunisal derivative; Endometrial adenocarcinoma cell Ishikawa; Lung cancer cell A549

Indexed keywords

AMIDE; ANTINEOPLASTIC AGENT; DIFLUNISAL; DIFLUNISAL DERIVATIVE; O ACETYLDIFLUNISAL; O BENZOYLDIFLUNISAL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

AMIDES; ANTI-INFECTIVE AGENTS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; CRYSTALLOGRAPHY, X-RAY; DIFLUNISAL; DRUG DESIGN; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NEOPLASMS;

EID: 67649971796     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.05.082     Document Type: Article

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