Application of the glucose hydrogen breath test for the detection of bacterial overgrowth in patients with cystic fibrosis - A reliable method?

Digestive Diseases and Sciences

Volumn 54, Issue 8, 2009, Pages 1730-1735

  Schneider, Arne R J ^a   Klueber, Stefanie ^a   Posselt, Hans Georg ^b   Funk, Benjamin ^b   Murzynski, Lydia ^a   Caspary, Wolfgang F ^a   Stein, Juergen ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Bacterial intestinal overgrowth; Breath testing; Cystic fibrosis; Glucose

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; CEPHALOSPORIN; CIPROFLOXACIN; GLUCOSE; HYDROGEN; MACROLIDE; PANCREAS ENZYME; PROTON PUMP INHIBITOR; TOBRAMYCIN;

ABDOMINAL DISCOMFORT; ABSENCE OF SIDE EFFECTS; ADOLESCENT; ADULT; ARTICLE; BACTERIAL OVERGROWTH; BREATHING; CHILD; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYSTIC FIBROSIS; DIAGNOSTIC ACCURACY; DIARRHEA; DIET RESTRICTION; DRUG MEGADOSE; EXHALATION; FEMALE; HUMAN; HYDROGEN BREATH TEST; INTESTINAL DYSMOTILITY; INTESTINE FLORA; MALABSORPTION; MALE; METEORISM; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; RELIABILITY; RETROSPECTIVE STUDY; SCHOOL CHILD; BREATH ANALYSIS; CASE CONTROL STUDY; EVALUATION; GASTROINTESTINAL MOTILITY; INTESTINE; INTESTINE ABSORPTION; METABOLISM; METHODOLOGY; MICROBIOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; BREATH TESTS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; FEMALE; GASTROINTESTINAL MOTILITY; GLUCOSE; HUMANS; HYDROGEN; INTESTINAL ABSORPTION; INTESTINES; MALE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 67649967255     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-008-0559-5     Document Type: Article

References (30)

1. RM Donaldson Jr 1970 Small bowel bacterial overgrowth Adv Intern Med 16 191 212
2. G Barbara V Stanghellini G Brandi 2005 Interactions between commensal bacteria and gut sensorimotor function in health and disease Am J Gastroenterol 100 2560 2568 10.1111/j.1572-0241.2005.00230.x
3. EM Quigley R Quera 2006 Small intestinal bacterial overgrowth: roles of antibiotics, prebiotics and probiotics Gastroenterology 130 S78 S90 10.1053/j.gastro.2005.11.046
4. E Husebye 2005 The pathogenesis of gastrointestinal bacterial overgrowth Chemotherapy 51 Suppl 1 1 22 10.1159/000081988
5. SA Gunnarsdottir R Sadik S Shev 2003 Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension Am J Gastroenterol 98 1362 1370 10.1111/j.1572-0241.2003. 07475.x
6. HC Lin 2004 Small intestinal bacterial overgrowth. A framework for understanding irritable bowel syndrome JAMA 292 852 858 10.1001/jama.292.7.852
7. CE King PP Toskes 1979 Small intestine bacterial overgrowth Gastroenterology 76 1035 1055 (Pubitemid 9250747)
8. JG Banwell LA Kistler RA Giannella FL Weber A Lieber DE Powell 1981 Small intestinal bacterial overgrowth syndrome Gastroenterology 80 834 845 (Pubitemid 11137771)
9. H Schjonsby T Hofstad 1975 The uptake of vitamin B12 by the sediment of jejunal contents in patients with blind loop syndrome Scand J Gastroenterol 10 305 309
10. EK Steffen RD Berg EA Deitch 1988 Comparison of translocation rates of various indigenous bacteria from the gastrointestinal tract to the mesenteric lymph node J Infect Dis 157 1023 1028
11. SM Riordan CJ McIver D Wakefield MC Thomas VM Dunscombe TD Bolin 1999 Serum immunoglobulin and soluble IL-2 receptor levels in small intestinal bacterial overgrowth with indigenous gut flora Dig Dis Sci 44 939 944 10.1023/A:1026652412554
12. A Bjorneklett O Fausa T Midtvedt 1983 Small-bowel bacterial overgrowth in the postgastrectomy syndrome Scand J Gastroenterol 18 277 287 (Pubitemid 13154212)
13. 14C-D-xylose and healthy controls Am J Gastroenterol 100 1566 1570 10.1111/j.1572-0241.2005. 40795.x
14. M Pimentel EJ Chow HC Lin 2000 Eradication of small intestinal bacterial overgrowth reduces symptomas of irritable bowel syndrome Am J Gastroenterol 95 3503 3506 10.1111/j.1572-0241.2000.03368.x
15. PJ Lewindon TA Robb DJ Moore GP Davidson AJ Martin 1998 Bowel dysfunction in cystic fibrosis: importance of breath testing J Paediatr Child Health 34 79 82 10.1046/j.1440-1754.1998.00159.x (Pubitemid 28158512)
16. JL Fridge C Conrad L Gerson RO Castillo K Cox 2007 Risk factors for small bowel bacterial overgrowth in cystic fibrosis J Pediatr Gastroenterol Nutr 44 212 218 10.1097/MPG.0b013e31802c0ceb
17. O Norkina TG Burnett RC de Lisle 2004 Bacterial overgrowth in the cystic fibrosis transmembrane conductance regulator null mouse small intestine Infect Immun 72 6040 6049 10.1128/IAI.72.10.6040-6049.2004
18. E Kerem S Conway S Elborn H Heijerman 2005 Consensus committee: standards of care for patients with cystic fibrosis: a European consensus J Cyst Fibros 4 7 26 10.1016/j.jcf.2004.12.002
19. P Kerlin L Wong 1988 Breath hydrogen testing in bacterial overgrowth of the small intestine Gastroenterology 95 982 988 (Pubitemid 18235542)
20. 2 breath tests in patients with small intestine bacterial overgrowth Gastroenterology 91 1447 1451 (Pubitemid 17176859)
21. CE King PP Toskes 1984 Breath tests in the diagnosis of small intestine bacterial overgrowth Crit Rev Clin Lab Sci 21 269 281
22. 2 breath test for small intestine bacterial overgrowth Gastroenterology 98 253 254 (Pubitemid 20017820)
23. J Keller A Franke M Storr 2005 Clinically relevant breath tests in gastroenterological diagnostics-recommendations of the German Society for Neurogastroenterology and Motility as well as the German Society for Digestive and Metabolic Diseases Z Gastroenterol 43 1071 1090 10.1055/s-2005-858479
24. O Norkina S Kaur D Ziemer RC De Lisle 2004 Inflammation of the cystic fibrosis mouse small intestine Am J Physiol Gastrointest Liver Physiol 286 G1032 G1041 10.1152/ajpgi.00473.2003
25. RC De Lisle EA Roach O Norkina 2006 Eradication of small intestinal bacterial overgrowth in the cystic fibrosis mouse reduces mucus accumulation J Pediatr Gastroenterol Nutr 42 46 52 10.1097/01.mpg.0000189322.34582.3e
26. J Romagnuolo D Schiller RJ Bailey 2002 Using breath tests wisely in a gastroenterology practice: an evidence-based review of indications and pitfalls in interpretation Am J Gastroenterol 97 1113 1126 10.1111/j.1572-0241.2002. 05664.x (Pubitemid 34478108)
27. A Bali DE Stableforth P Asquith 1983 Prolonged small-intestinal transit time in cystic fibrosis Br Med J (Clin Res Ed) 287 1011 1013
28. PC Gregory 1996 Gastrointestinal pH, motility/transit and permeability in cystic fibrosis J Pediatr Gastroenterol Nutr 23 513 523 10.1097/00005176- 199612000-00001
29. 51Cr-EDTA and orocecal transit time in cystic fibrosis J Pediatr Gastroenterol Nutr 14 204 207 10.1097/00005176- 199202000-00015
30. AM Dalzell NS Freestone D Billington DP Heaf 1990 Small intestinal permeability and orocaecal transit time in cystic fibrosis Arch Dis Child 65 585 588 (Pubitemid 20193632)