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Volumn 21, Issue 6, 2009, Pages 1525-1528

Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA-MB 468 breast cancer cells due to CYP1 activation

Author keywords

Antiproliferative activity; Cell cycle arrest; CYP1 enzymes; Diosmetin; Luteolin

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DIOSMETIN; LUTEOLIN; ANTINEOPLASTIC AGENT; CYP1B1 PROTEIN, HUMAN; CYTOCHROME P450; ENZYME ACTIVATOR; FLAVONOID;

EID: 67649935021     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000384     Document Type: Article
Times cited : (81)

References (20)
  • 1
    • 34250191810 scopus 로고    scopus 로고
    • Antioxidant and anticancer activity of 3′-formyl-4′, 6′-dihydroxy-2′-methoxy-5′-methylchalcone and (2S)-8-formyl-5-hydroxy-7-methoxy-6-methylflavanone
    • Ye CL, Liu Y and Wei DZ: Antioxidant and anticancer activity of 3′-formyl-4′, 6′-dihydroxy-2′-methoxy-5′-methylchalcone and (2S)-8-formyl-5-hydroxy-7-methoxy-6-methylflavanone. J Pharm Pharmacol 59: 553-559, 2007.
    • (2007) J Pharm Pharmacol , vol.59 , pp. 553-559
    • Ye, C.L.1    Liu, Y.2    Wei, D.Z.3
  • 2
    • 33751082422 scopus 로고    scopus 로고
    • Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2)
    • Granado-Serrano AB, Martín MA, Bravo L, Goya L and Ramos S: Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2). J Nutr 136: 2715-2721, 2006.
    • (2006) J Nutr , vol.136 , pp. 2715-2721
    • Granado-Serrano, A.B.1    Martín, M.A.2    Bravo, L.3    Goya, L.4    Ramos, S.5
  • 3
    • 33748355855 scopus 로고    scopus 로고
    • Modulation of activator protein-1 (AP-1) and MAPK pathway by flavonoids in human prostate cancer PC3 cells
    • Gopalakrishnan A, Xu CJ, Nair SS, Chen C, Hebbar V and Kong AN: Modulation of activator protein-1 (AP-1) and MAPK pathway by flavonoids in human prostate cancer PC3 cells. Arch Pharmaceut Res 8: 633-644, 2006.
    • (2006) Arch Pharmaceut Res , vol.8 , pp. 633-644
    • Gopalakrishnan, A.1    Xu, C.J.2    Nair, S.S.3    Chen, C.4    Hebbar, V.5    Kong, A.N.6
  • 4
    • 55749110433 scopus 로고    scopus 로고
    • Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB 468 human breast cancer cells due to CYP1 mediated metabolism
    • Androutsopoulos V, Arroo RR, Hall JF, Surichan S and Potter GA: Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB 468 human breast cancer cells due to CYP1 mediated metabolism. Breast Cancer Res 10: R39, 2008.
    • (2008) Breast Cancer Res , vol.10
    • Androutsopoulos, V.1    Arroo, R.R.2    Hall, J.F.3    Surichan, S.4    Potter, G.A.5
  • 5
    • 33746690306 scopus 로고    scopus 로고
    • Metabolism of the soyabean isoflavone daidzein by CYP1A2 and the extra-hepatic CYPs 1A1 and 1B1 affects biological activity
    • Atherton K, Mutch E and Ford D: Metabolism of the soyabean isoflavone daidzein by CYP1A2 and the extra-hepatic CYPs 1A1 and 1B1 affects biological activity. Biochem Pharmacol 72: 624-631, 2006.
    • (2006) Biochem Pharmacol , vol.72 , pp. 624-631
    • Atherton, K.1    Mutch, E.2    Ford, D.3
  • 7
    • 4444223732 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes: Novel options for cancer therapeutics
    • McFadyen MCE, Melvin WT and Murray GI: Cytochrome P450 enzymes: novel options for cancer therapeutics. Mol Cancer Ther 3: 363-371, 2004.
    • (2004) Mol Cancer Ther , vol.3 , pp. 363-371
    • McFadyen, M.C.E.1    Melvin, W.T.2    Murray, G.I.3
  • 8
    • 22244433506 scopus 로고    scopus 로고
    • In vitro antioxidant activity of some Teucrium species (Lamiaceae)
    • Kadifkova Panovska T, Kulevanova S and Stefova M: In vitro antioxidant activity of some Teucrium species (Lamiaceae). Acta Pharm 55: 207-214, 2005.
    • (2005) Acta Pharm , vol.55 , pp. 207-214
    • Kadifkova Panovska, T.1    Kulevanova, S.2    Stefova, M.3
  • 10
    • 57749091536 scopus 로고    scopus 로고
    • Bioactivation of the phytoestrogen diosmetin by CYP1 cytochromes P450
    • Androutsopoulos V, Wilsher N, Arroo RRJ and Potter GA: Bioactivation of the phytoestrogen diosmetin by CYP1 cytochromes P450. Cancer Lett 274: 54-60, 2009.
    • (2009) Cancer Lett , vol.274 , pp. 54-60
    • Androutsopoulos, V.1    Wilsher, N.2    Arroo, R.R.J.3    Potter, G.A.4
  • 11
    • 22844440224 scopus 로고    scopus 로고
    • Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones
    • Browning AM, Walle UK and Walle T: Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. J Pharm Pharmacol 57: 1037-1042, 2005.
    • (2005) J Pharm Pharmacol , vol.57 , pp. 1037-1042
    • Browning, A.M.1    Walle, U.K.2    Walle, T.3
  • 12
    • 0032126507 scopus 로고    scopus 로고
    • Diosmin and diosmetin are agonists of the aryl hydrocarbon receptor that differentially affect cytochrome P450 1A1 activity
    • Ciolino HP, Wang TTY and Yeh GC: Diosmin and diosmetin are agonists of the aryl hydrocarbon receptor that differentially affect cytochrome P450 1A1 activity. Cancer Res 58: 2754-2760, 1998.
    • (1998) Cancer Res , vol.58 , pp. 2754-2760
    • Ciolino, H.P.1    Wang, T.T.Y.2    Yeh, G.C.3
  • 13
    • 0034599543 scopus 로고    scopus 로고
    • Bioflavonoids: Selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1
    • Doostdar H, Burke MD and Mayer RT: Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1. Toxicology 144: 31-38, 2000.
    • (2000) Toxicology , vol.144 , pp. 31-38
    • Doostdar, H.1    Burke, M.D.2    Mayer, R.T.3
  • 14
    • 33846179993 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin
    • Lim do Y, Jeong Y, Tyner AL and Park JH: Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin. Am J Physiol 292: G66-G75, 2007.
    • (2007) Am J Physiol , vol.292
    • Lim do, Y.1    Jeong, Y.2    Tyner, A.L.3    Park, J.H.4
  • 15
    • 0035874028 scopus 로고    scopus 로고
    • Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: Regulation of cyclin-dependent kinases CDK2 and CDK1
    • Casagrande F and Darbon JM: Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1. Biochem Pharmacol 61: 1205-1215, 2001.
    • (2001) Biochem Pharmacol , vol.61 , pp. 1205-1215
    • Casagrande, F.1    Darbon, J.M.2
  • 16
    • 13444282282 scopus 로고    scopus 로고
    • Increase of Bax/Bcl-XL ratio and arrest of cell cycle by luteolin in immortalised human hepatoma cell line
    • Chang J, Hsu Y, Kuo P, Kuo Y, Chiang L and Lin C: Increase of Bax/Bcl-XL ratio and arrest of cell cycle by luteolin in immortalised human hepatoma cell line. Life Sci 76: 1883-1893, 2005.
    • (2005) Life Sci , vol.76 , pp. 1883-1893
    • Chang, J.1    Hsu, Y.2    Kuo, P.3    Kuo, Y.4    Chiang, L.5    Lin, C.6
  • 17
    • 0032756794 scopus 로고    scopus 로고
    • Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells over-expressing epidermal growth factor receptor
    • Huang YT, Hwang JJ, Lee PP, Ke FC, Huang JH, Huang CJ, Kandaswami C, Middleton E and Lee MT: Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells over-expressing epidermal growth factor receptor. Br J Pharmacol 128: 999-1010, 1999.
    • (1999) Br J Pharmacol , vol.128 , pp. 999-1010
    • Huang, Y.T.1    Hwang, J.J.2    Lee, P.P.3    Ke, F.C.4    Huang, J.H.5    Huang, C.J.6    Kandaswami, C.7    Middleton, E.8    Lee, M.T.9
  • 18
    • 0037299799 scopus 로고    scopus 로고
    • Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells
    • Squires MS, Hudson EA, Howells L, Sale S, Houghton CE, Jones JL, Fox LH, Dickens M, Prigent SA and Manson MM: Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells. Biochem Pharmacol 65: 361-376, 2003.
    • (2003) Biochem Pharmacol , vol.65 , pp. 361-376
    • Squires, M.S.1    Hudson, E.A.2    Howells, L.3    Sale, S.4    Houghton, C.E.5    Jones, J.L.6    Fox, L.H.7    Dickens, M.8    Prigent, S.A.9    Manson, M.M.10
  • 19
    • 4444242518 scopus 로고    scopus 로고
    • Targeted inhibition of the epidermal growth factor receptor-tyrosine kinase by ZD1839 ('Iressa') induces cell-cycle arrest and inhibits proliferation in prostate cancer cells
    • Sgambato A, Camerini A, Faraglia B, Ardito R, Bianchino G, Spada D, Boninsegna A, Valentini V and Cittadini A: Targeted inhibition of the epidermal growth factor receptor-tyrosine kinase by ZD1839 ('Iressa') induces cell-cycle arrest and inhibits proliferation in prostate cancer cells. J Cell Physiol 201: 97-105, 204.
    • J Cell Physiol , vol.201 , Issue.97-105 , pp. 204
    • Sgambato, A.1    Camerini, A.2    Faraglia, B.3    Ardito, R.4    Bianchino, G.5    Spada, D.6    Boninsegna, A.7    Valentini, V.8    Cittadini, A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.