Effect of topical 0.5% povidone-iodine compared to 5% natamycin in fungal keratitis caused by Fusarium solani in a rabbit model: A pilot study;Efeito tópico de iodo-povidona 0,5% comparado com natamicina 5% em ceratites fúngicas causadas por Fusarium solani em um modelo animal de coelhos: Estudo piloto

Arquivos Brasileiros de Oftalmologia

Volumn 71, Issue 6, 2008, Pages 860-864

  de Oliveira, Lauro Augusto ^a,b   Takata, Thales Takeo ^a   Shiguematsu, Alvio Isao ^a   Melo Jr , Luiz Alberto Soares ^a   Gompertz, Olga Fischman ^a   de Sousa, Luciene Barbosa ^a   Mannis, Mark J ^b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antifungal agents administration; Antifungal agents therapeutic use; Dosage; Eye infections; Fungal drug therapy; Fusarium; Keratitis microbiology; Natamycin administration; Natamycin therapeutic use; Povidone iodine administration; Povidoneiodine therapeutic use

Indexed keywords

ANTIFUNGAL AGENT; NATAMYCIN; POVIDONE IODINE;

ANIMAL; ARTICLE; BACTERIAL COUNT; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE MODEL; FUSARIUM; GROWTH, DEVELOPMENT AND AGING; KERATITIS; MALE; MICROBIOLOGY; PILOT STUDY; RABBIT; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL;

ANIMALS; ANTIFUNGAL AGENTS; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; FUSARIUM; KERATITIS; MALE; NATAMYCIN; PILOT PROJECTS; POVIDONE-IODINE; RABBITS; RANDOM ALLOCATION;

EID: 67649891844     PISSN: 00042749     EISSN: 16782925     Source Type: Journal    
DOI: 10.1590/s0004-27492008000600018     Document Type: Article

References (20)

1. Foster CS. Fungal keratitis. Infect Dis Clin North Am. 1992;6(4):851-7.
2. Martin MJ, Rahman MR, Johnson GJ, Srinivasan M, Clayton YM. Mycotic keratitis: susceptibility to antiseptic agents. Int Ophthalmol. 1995-1996;19(5):299-302.
3. Thomas PA. Mycotic keratitis - an underestimated mycosis. J Med Vet Mycol. 1994;32(4):235-56.
4. Sousa BL. Estudo experimental da eficácia da sulfadiazina de prata a 1% no tratamento da ceratite por Fusarium solani [tese]. São Paulo: Universidade Federal de São Paulo. Escola Paulista de Medicina; 1993.
5. Höfling-Lima AL, Forseto A, Duprat JP, Andrade A, Souza LB, Godoy P, Freitas D. Estudo laboratorial das micoses oculares e fatores associados às ceratites. Arq Bras Oftalmol. 2005;68(1):21-7.
6. Rosa RH Jr, Miller D, Alfonso EC. The changing spectrum of fungal keratitis in south Florida. Ophthalmology. 1994;101(6):1005-13.
7. Tanure MA, Cohen EJ, Sudesh S, Rapuano CJ, Laibson PR. Spectrum of fungal keratitis at Wills Eye Hospital, Philadelphia, Pennsylvania. Cornea. 2000;19(3): 307-12.
8. Prajna NV, John RK, Nirmalan PK, Lalitha P, Srinivasan M. A randomised clinical trial comparing 2% econazole and 5% natamycin for the treatment of fungal keratitis. Br J Ophthalmol. 2003;87(10):1235-7.
9. Kalavathy CM, Parmar P, Kaliamurthy J, Philip VR, Ramalingam MD, Jesudasan CA, Thomas PA. Comparison of topical itraconazole 1% with topical natamycin 5% for the treatment of filamentous fungal keratitis. Cornea. 2005;24(4):449-52.
10. Apt L, Isenberg S, Yoshimori R, Paez JH. Chemical preparation of the eye in ophthalmic surgery. III. Effect of povidone-iodine on the conjunctiva. Arch Ophthalmol. 1984;102(5):728-9.
11. Boes DA, Lindquist TD, Fritsche TR, Kalina RE. Effects of povidone-iodine chemical preparation and saline irrigation on the perilimbal flora. Ophthalmology. 1992;99(10):1569-74.
12. White JH, Stephens GM, Cinotti AA. The use of povidone-iodine for treatment of fungi in rabbit eyes. Ann Ophthalmol. 1972;4(10):855-6.
13. Fiscella RG, Moshifar M, Messick CR, Pendland SL, Chandler JW, Viana M. Polyhexamethylene biguanide (PHMB) in the treatment of experimental Fusarium keratomycosis. Cornea. 1997;16(4):447-9.
14. O'Day DM, Ray WA, Head WS, Robinson RD, Williams TE. Influence of corticosteroid on experimentally induced keratomycosis. Arch Ophthalmol. 1991; 109(11):1601-4.
15. Mitchell BM, Wilhelmus KR. Inflammatory response to fungal keratitis. Ocul Surf. 2005;3(Suppl 4):S152-3.
16. Kiryu H, Yoshida S, Suenaga Y, Asahi M. Invasion and survival of Fusarium solani in the dexamethasone-treated cornea of rabbits. J Med Vet Mycol. 1991; 29(6):395-406.
17. Sloop GD, Moreau JM, Conerly LL, Dajcs JJ, O'Callaghan RJ. Acute inflam- mation of the eyelid and cornea in Staphylococcus keratitis in the rabbit. Invest Ophthalmol Vis Sci. 1999;40(2):385-91.
18. York KK, Miller S, Gaster RN, Burstein NL. Polyvinylpyrrolidone iodine: corneal toxicology and epithelial healing in a rabbit model. J Ocul Pharmacol. 1988;4(4):351-8.
19. Alfonso EC, Cantu-Dibildox J, Munir WM, Miller D, O'Brien TP, Karp CL, et al. Insurgence of Fusarium keratitis associated with contact lens wear. Arch Ophthalmol. 2006;124(7):941-7. Comment in: Arch Ophthalmol. 2006;124(8): 1183-4. Comment on: Arch Ophthalmol. 2006;124(7):1051-3.
20. Marangon FB, Miller D, Giaconi JA, Alfonso EC. In vitro investigation of voriconazole susceptibility for keratitis and endophthalmitis fungal pathogens. Am J Ophthalmol. 2004;137(5):820-5.