Can topical calcipotriol be a treatment alternative in actinic keratoses? A preliminary report

Journal of Drugs in Dermatology

Volumn 8, Issue 5, 2009, Pages 451-454

  Seckin, Dilek ^a   Cerman, Asli Aksu ^a   Yildiz, Ayfer ^a   Ergun, Tulin ^a  

^a MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIPOTRIOL; PLACEBO; CALCITRIOL; DERMATOLOGICAL AGENT; DRUG DERIVATIVE;

ACTINIC KERATOSIS; ADULT; AGED; ALTERNATIVE MEDICINE; ARTICLE; BURNING SENSATION; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DRUG EFFICACY; DRY SKIN; ERYTHEMA; FACE; FEMALE; HUMAN; MALE; SCALP; SCORING SYSTEM; SKIN PRURITUS; TREATMENT DURATION; CLINICAL TRIAL; DRUG ADMINISTRATION; MIDDLE AGED; SINGLE BLIND PROCEDURE; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; AGED; AGED, 80 AND OVER; CALCITRIOL; DERMATOLOGIC AGENTS; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; KERATOSIS, ACTINIC; MALE; MIDDLE AGED; SINGLE-BLIND METHOD;

EID: 67649863740     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Van den Bemd GJ, Chang GT. Vitamin D and vitamin D analogs in cancer treatment. Curr Drug Targets. 2002;3(1):85-94. (Pubitemid 34296306)
2. Bower M, Colston KW, Stein RC, et al. Topical calcipotriol treatment in advanced breast cancer. Lancet. 1991;337(8743):701-702.
3. Raina V, Cunningham D, Gilchrist N, Soukop M. Alfacalcidol is a nontoxic, effective treatment of follicular small-cleaved cell lymphoma. Br J Cancer. 1991;63(3):463-465.
4. Gulliford T, English J, Colston KW, et al. A phase I study of the vitamin D analogue EB 1089 in patients with advanced breast and colorectal cancer. Br J Cancer. 1998;78(1):6-13. (Pubitemid 28276762)
5. Tuohimaa P, Pukkala E, Scelo G, et al. Does solar exposure, as indicated by non-melanoma skin cancers, protect from solid cancers: Vitamin D as a possible explanation. Eur J Cancer. 2007;43(11):1701-1712. (Pubitemid 47049676)
6. French LE, Ramelet AA, Saurat JH. Remission of cutaneous T-cell lymphoma with combined calcitriol and acitretin. Lancet. 1994;344(8923):686-687. (Pubitemid 24274330)
7. Thomsen K. Cutaneous T-cell lymphoma and calcitriol and isotretinoin treatment. Lancet. 1995;345(8964):1583.
8. Majewski S, Skopinska M, Bollag W, Jablonska S. Combination of isotretinoin and calcitriol for precancerous and cancerous skin lesions. Lancet. 1994;344(8935):1510-1511. (Pubitemid 24351726)
9. Reichrath J, Rafi L, Rech M, et al. Analysis of the vitamin D system in cutaneous squamous cell carcinomas. J Cutan Pathol. 2004;31(3):224-231. (Pubitemid 38230564)
10. Lu J, Goldstein KM, Chen P, et al. Transcriptional profiling of keratinocytes reveals a vitamin D-regulated epidermal differentiation network. J Invest Dermatol. 2005;124(4):778-785. (Pubitemid 40489505)
11. Gupta AK, Browne M, Bluhm R. Nonpsoriatic uses of calcipotriol. J Cutan Med Surg. 2002;6(5):442-448. (Pubitemid 35283412)
12. Smit JV, Cox S, Blokx WA, et al. Actinic keratosis in renal transplant recipients do not improve with calcipotriol cream and all-trans retinoic acid cream as monotherapies or in combination during a 6-week treatment period. Br J Dermatol. 2002;147(4):816-818. (Pubitemid 35286183)
13. Dixon KM, Deo SS, Wong G, et al. Skin cancer prevention: A possible role of 1,25dihydroxyvitamin D3 and its analogs. J Steroid Biochem Mol Biol. 2005;97(1-2):137-143. (Pubitemid 41546223)