Modulation of protein-ligand interactions by photocleavage of a cyclic peptide using phosphatidylinositol 3-kinase SH3 domain as model system

Journal of Peptide Science

Volumn 15, Issue 6, 2009, Pages 411-416

  Takahashi, Isao ^a   Kuroiwa, Shigeki ^b   Lindfors, Hanna E ^c   Ndamba, Lionel A ^c   Hiruma, Yoshitaka ^c   Yajima, Tatsuo ^b   Okishio, Nobuyuki ^d   Ubbink, Marcellus ^c   Hirota, Shun ^a,b  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c LEIDEN UNIVERSITY   (Netherlands)

^d KANAZAWA UNIVERSITY   (Japan)

Author keywords

Cyclic peptide; Phosphatidylinositol 3 kinase SH3 domain; Photocleavage; Photomodulation; Protein peptide interaction; RLP1 peptide

Indexed keywords

CYCLOPEPTIDE; DITHIOTHREITOL; PHOSPHATIDYLINOSITOL 3 KINASE; LIGAND;

ARTICLE; BINDING AFFINITY; LIGAND BINDING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; ULTRAVIOLET IRRADIATION; BIOLOGICAL MODEL; CHEMISTRY; CIRCULAR DICHROISM; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY; RADIATION EXPOSURE; SRC HOMOLOGY DOMAIN; SYNTHESIS; ULTRAVIOLET RADIATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CIRCULAR DICHROISM; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN CONFORMATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SRC HOMOLOGY DOMAINS; ULTRAVIOLET RAYS;

EID: 67649757123     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1132     Document Type: Article

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