The presence of γ′ chain impairs fibrin polymerization

Thrombosis Research

Volumn 124, Issue 3, 2009, Pages 356-363

  Gersh, Kathryn C ^a   Nagaswami, Chandrasekaran ^c   Weisel, John W ^c   Lord, Susan T ^a,b  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Chain; Blood Coagulation; Fibrinogen; Polymerization

Indexed keywords

FIBRINOGEN VARIANT; FIBRINOPEPTIDE; FIBRINOPEPTIDE A; FIBRINOPEPTIDE B; GLYCOPEPTIDASE; HETERODIMER; HOMODIMER; THROMBIN; TYROSINE; FIBRIN; FIBRINOGEN;

ANIMAL CELL; ARTICLE; BLOOD CLOT; CATALYSIS; CHO CELL; FIBRIN CLOT; FIBRIN POLYMERIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; SCANNING ELECTRON MICROSCOPY; SULFATION; TURBIDITY; ANIMAL; CRICETULUS; DIMERIZATION; GENETICS; HAMSTER; METABOLISM;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DIMERIZATION; FIBRIN; FIBRINOGEN; THROMBIN;

EID: 67649710434     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2008.11.016     Document Type: Article

References (33)

1. Fornace Jr. A.J., Cummings D.E., Comeau C.M., Kant J.A., and Crabtree G.R. Structure of the human gamma-fibrinogen gene. Alternate mRNA splicing near the 3′ end of the gene produces gamma A and gamma B forms of gamma-fibrinogen. J Biol Chem 259 (1984) 12826-12830
2. Chung D.W., and Davie E.W. gamma and gamma' chains of human fibrinogen are produced by alternative mRna processing. Biochemistry 23 (1984) 4232-4236
3. Wolfenstein-Todel C., and Mosesson M.W. Carboxy-terminal amino acid sequence of a human fibrinogen gamma-chain variant (gamma'). Biochemistry 20 (1981) 6146-6149
4. Mosesson M.W., and Finlayson J.S. Biochemical and chromatographic studies of certain activities associated with human fibrinogen preparations. J Clin Invest 42 (1963) 747-755
5. Mosesson M.W., Finlayson J.S., and Umfleet R.A. Human fibrinogen heterogeneities. 3. Identification of chain variants. J Biol Chem 247 (1972) 5223-5227
6. Mannila M.N., Lovely R.S., Kazmierczak S.C., Eriksson P., Samnegard A., Farrell D.H., et al. Elevated plasma fibrinogen gamma' concentration is associated with myocardial infarction: effects of variation in fibrinogen genes and environmental factors. J Thromb Haemost 5 (2007) 766-773
7. Lovely R.S., Falls L.A., Al-Mondhiry H.A., Chambers C.E., Sexton G.J., Ni H., et al. Association of gammaA/gamma' fibrinogen levels and coronary artery disease. Thromb Haemost 88 (2002) 26-31
8. Drouet L., Paolucci F., Pasqualini N., Laprade M., Ripoll L., Mazoyer E., et al. Plasma gamma'/gamma fibrinogen ratio, a marker of arterial thrombotic activity: a new potential cardiovascular risk factor?. Blood Coagul Fibrinolysis 10 Suppl 1 (1999) S35-39
9. Cheung E.Y., Uitte de Willige S., Vos H.L., Leebeek F.W., Dippel D.W., Bertina R.M., et al. Fibrinogen gamma' in ischemic stroke: a case-control study. Stroke 39 (2008) 1033-1035
10. Uitte de Willige S., de Visser M.C., Houwing-Duistermaat J.J., Rosendaal F.R., Vos H.L., and Bertina R.M. Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma' levels. Blood 106 (2005) 4176-4183
11. Mosesson M.W., Hernandez I., Raife T.J., Medved L., Yakovlev S., Simpson-Haidaris P.J., et al. Plasma fibrinogen gamma' chain content in the thrombotic microangiopathy syndrome. J Thromb Haemost 5 (2007) 62-69
12. Meh D.A., Siebenlist K.R., and Mosesson M.W. Identification and characterization of the thrombin binding sites on fibrin. J Biol Chem 271 (1996) 23121-23125
13. Meh D.A., Siebenlist K.R., Brennan S.O., Holyst T., and Mosesson M.W. The amino acid sequence in fibrin responsible for high affinity thrombin binding. Thromb Haemost 85 (2001) 470-474
14. Mosesson M.W. Update on antithrombin I (fibrin). Thromb Haemost 98 (2007) 105-108
15. Siebenlist K.R., Meh D.A., and Mosesson M.W. Plasma factor XIII binds specifically to fibrinogen molecules containing gamma chains. Biochemistry 35 (1996) 10448-10453
16. Kazama M., McDonagh J., Wagner R.H., Langdell R.D., and McDonagh R.P. Purification and immunochemical characterization of human plasma factor XIII. Haemostasis 5 (1976) 329-340
17. Cooper A.V., Standeven K.F., and Ariens R.A. Fibrinogen gamma-chain splice variant gamma' alters fibrin formation and structure. Blood 102 (2003) 535-540
18. Collet J.P., Nagaswami C., Farrell D.H., Montalescot G., and Weisel J.W. Influence of gamma' fibrinogen splice variant on fibrin physical properties and fibrinolysis rate. Arterioscler Thromb Vasc Biol 24 (2004) 382-386
19. Siebenlist K.R., Mosesson M.W., Hernandez I., Bush L.A., Di Cera E., Shainoff J.R., et al. Studies on the basis for the properties of fibrin produced from fibrinogen-containing gamma' chains. Blood 106 (2005) 2730-2736
20. Lord S.T., Strickland E., and Jayjock E. Strategy for recombinant multichain protein synthesis: fibrinogen B beta-chain variants as thrombin substrates. Biochemistry 35 (1996) 2342-2348
21. Gorkun O.V., Veklich Y.I., Weisel J.W., and Lord S.T. The conversion of fibrinogen to fibrin: recombinant fibrinogen typifies plasma fibrinogen. Blood 89 (1997) 4407-4414
22. Mullin J.L., Gorkun O.V., and Lord S.T. Decreased lateral aggregation of a variant recombinant fibrinogen provides insight into the polymerization mechanism. Biochemistry 39 (2000) 9843-9849
23. Weisel J.W., and Nagaswami C. Computer modeling of fibrin polymerization kinetics correlated with electron microscope and turbidity observations: clot structure and assembly are kinetically controlled. Biophys J 63 (1992) 111-128
24. Wolfenstein-Todel C., and Mosesson M.W. Human plasma fibrinogen heterogeneity: evidence for an extended carboxyl-terminal sequence in a normal gamma chain variant (gamma'). Proc Natl Acad Sci U S A 77 (1980) 5069-5073
25. Lovely R.S., Moaddel M., and Farrell D.H. Fibrinogen gamma' chain binds thrombin exosite II. J Thromb Haemost 1 (2003) 124-131
26. Sabo T.M., Farrell D.H., and Maurer M.C. Conformational Analysis of gamma' Peptide (410-427) Interactions with Thrombin Anion Binding Exosite II. Biochemistry 45 (2006) 7434-7445
27. Hooker A.D., Goldman M.H., Markham N.H., James D.C., Ison A.P., Bull A.T., et al. N-glycans of recombinant human interferon-gamma change during batch culture of chinese hamster ovary cells. Biotechnol Bioeng 48 (1995) 639-648
28. Woodhead J.L., Nagaswami C., Matsuda M., Arocha-Pinango C.L., and Weisel J.W. The ultrastructure of fibrinogen Caracas II molecules, fibers, and clots. J Biol Chem 271 (1996) 4946-4953
29. Hamano A., Mimuro J., Aoshima M., Itoh T., Kitamura N., Nishinarita S., et al. Thrombophilic dysfibrinogen Tokyo V with the amino acid substitution of gammaAla327Thr: formation of fragile but fibrinolysis-resistant fibrin clots and its relevance to arterial thromboembolism. Blood 103 (2004) 3045-3050
30. Ruf W., Bender A., Lane D.A., Preissner K.T., Selmayr E., and Muller-Berghaus G. Thrombin-induced fibrinopeptide B release from normal and variant fibrinogens: influence of inhibitors of fibrin polymerization. Biochim Biophys Acta 965 (1988) 169-175
31. Pechik I., Yakovlev S., Mosesson M.W., Gilliland G.L., and Medved L. Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly. Biochemistry 45 (2006) 3588-3597
32. Lovely R.S., Boshkov L.K., Marzec U.M., Hanson S.R., and Farrell D.H. Fibrinogen gamma' chain carboxy terminal peptide selectively inhibits the intrinsic coagulation pathway. Br J Haematol 139 (2007) 494-503
33. Collet J.P., Park D., Lesty C., Soria J., Soria C., Montalescot G., et al. Influence of Fibrin Network Conformation and Fibrin Fiber Diameter on Fibrinolysis Speed : Dynamic and Structural Approaches by Confocal Microscopy. Arterioscler Thromb Vasc Biol 20 (2000) 1354-1361