Induction of the ovulatory LH surge in Asian elephants (Elephas maximus): A novel aid in captive breeding management of an endangered species

Reproduction, Fertility and Development

Volumn 21, Issue 5, 2009, Pages 672-678

  Thitaram, Chatchote ^a,b   Pongsopawijit, Pornsawan ^a   Chansitthiwet, Saran ^c   Brown, Janine L ^d   Nimtragul, Kannikar ^e   Boonprasert, Khajhonpat ^c   Homkong, Pongpon ^c   Mahasawangkul, Sittidet ^c   Rojanasthien, Suvichai ^a   Colenbrander, Ben ^b   Van Der Weijden, Gysbert C ^b   Van Eerdenburg, Frank J C M ^b  

^a CHIANG MAI UNIVERSITY   (Thailand)

^b UTRECHT UNIVERSITY   (Netherlands)

^c National Elephant Institute   (Thailand)

^d SMITHSONIAN CONSERVATION BIOLOGY INSTITUTE   (United States)

^e Chiang Mai Neurological Hospital   (Thailand)

Author keywords

Gonadotropin releasing hormone; Ovulation induction

Indexed keywords

GESTAGEN; GONADORELIN; LUTEINIZING HORMONE;

ANIMAL EXPERIMENT; ARTICLE; BREEDING; CONTROLLED STUDY; ELEPHANT; ELEPHAS MAXIMUS; ENDANGERED SPECIES; ESTRUS CYCLE; FEMALE; FOLLICULAR PHASE; HORMONE RESPONSE; LUTEAL PHASE; LUTEINIZING HORMONE RELEASE; NONHUMAN; OVULATION INDUCTION;

ANIMAL HUSBANDRY; ANIMALS; BREEDING; BUSERELIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELEPHANTS; ESTRUS; FEMALE; FOLLICULAR PHASE; GONADOTROPIN-RELEASING HORMONE; LUTEINIZING HORMONE; OVULATION; OVULATION INDUCTION;

ELEPHAS MAXIMUS;

EID: 67649695568     PISSN: 10313613     EISSN: None     Source Type: Journal    
DOI: 10.1071/RD08296     Document Type: Article

References (25)

1. Brown, J. L. (2000). Reproductive endocrine monitoring of elephants: an essential tool for assisting captive management. Zoo Biol. 19, 347-367. doi:10.1002/1098-2361(2000)19:5<347::AID-ZOO6>3.0.CO;2-V
2. Brown, J. L., and Lehnhardt, J. (1997). Secretory patterns of serum prolactin in Asian (Elephas maximus) and African (Loxodonta africana) elephants during different reproductive states: comparison with concentrations in a noncycling African elephant. Zoo Biol. 16, 149- 159. doi:10.1002/(SICI)1098-2361(1997)16:2149::AID-ZOO5>3.0. CO;2-A
3. Brown, J., Hildebrandt, T., Theison, W., and Neiffer, D. (1999a). Endocrine and ultrasound evaluation of a non-cycling African elephant: identification of an ovarian follicular cyst. Zoo Biol. 18, 223- 232. doi:10.1002/(SICI)1098-2361(1999)18:3<223::AID-ZOO6>3.0. CO;2-F
4. Brown, J. L., Schmitt, D. L., Bellem, A., Graham, L. H., and Lehn-hardt, J. (1999b). Hormone secretion in the Asian elephant (Elephas maximus): characterization of ovulatory and anovulatory luteiniz-ing hormone surges. Biol. Reprod. 61, 1294-1299. doi:10.1095/ BIOLREPROD61.5.1294
5. Brown, J. L., Goritz, F., Pratt-Hawkes, N., Hermes, R., Galloway, M., et al. (2004). Successful artificial insemination of an Asian elephant at the National Zoological Park. Zoo Biol. 23, 45-63. doi:10.1002/ZOO.10116
6. Chappel, S. C., and Schmidt, M. (1979). Cyclic release of luteinizing hormone and the effectsofluteinizing hormone-releasing hormone injection in Asiatic elephants. Am. J. Vet. Res. 40, 451-453.
7. Czekala, N. M., MacDonald, E. A., Steinman, K., Walker, S., Garrigues, N. W., and Olson, D. (2003). Estrogen and LH dynamics during the follicular phase of the estrous cycle in the Asian elephant. Zoo Biol. 22, 443-454. doi:10.1002/ZOO.10098
8. 2α, GnRH, hCG and oestrus synchronization in cattle. Reprod. Domest. Anim. 34, 49-59. doi:10.1046/J.1439-0531.1999. 00175.X
9. Graham, L. H., Bolling, J., Miller, G., Pratt-Hawkes, N., and Joseph, S. (2002). Enzyme-immunoassay for the measurement of luteinizing hormone in the serum ofAfrican elephants (Loxodonta africana). Zoo Biol. 21, 403-408. doi:10.1002/ZOO.10051
10. Heistermann, M., Trohorsch, B., and Hodges, J. K. (1997). Assessment of ovarian function in the African elephant (Loxodonta africana) by measurement of 5α-reduced progesterone metabolites in serum and urine. Zoo Biol. 16, 273-284. doi:10.1002/(SICI)1098-2361(1997)16:3 <273::AID-ZOO7>3.0.CO;2-7
11. Hermes, R., Olson, D., Göritz, F., Brown, J. L., Schmitt, D. L., Hagan, D., Peterson, J. S., Fritsch, G., and Hildebrandt, T. B. (2000). Ultrasonography of the estrous cycle in female African elephants (Loxodonta africana). Zoo Biol. 19, 369-382. doi:10.1002/1098-2361(2000)19: 5<369::AID-ZOO7>3.0.CO;2-K
12. Hermes, R., Goritz, F., Streich, W., and Hildebrandt, T. (2007). Assisted reproduction in female rhinoceros and elephants: current status and future perspective. Reprod. Domest. Anim. 42(Suppl.), 33-44. doi:10.1111/J.1439-0531.2007.00924.X
13. Hildebrandt, T. B., Goeritz, F., Hermes, R., Reid, C., Dehnhard, M., and Brown, J. L. (2006). Aspects of the reproductive biology and breeding management of Asian and African elephants: Elephas maximus and Loxodonta africana. Int. Zoo Yb. 40, 20-40. doi:10.1111/J.1748-1090.2006.00020. X
14. Hodges, J. K. (1998). Endocrinology of the ovarian cycle and pregnancy in theAsian (Elephas maximus) andAfrican (Loxodontaafricana) elephant. Anim. Reprod. Sci. 53, 3-18. doi:10.1016/S0378-4320(98) 00123-7
15. Jagger, J. P., Peters, A. R., and Lamming, G. E. (1987). Hormone responses to low-dose GnRH treatment in post-partum beef cows. J. Reprod. Fertil. 80, 263-269. doi:10.1530/JRF.0.0800263
16. Leong, K. M., Ortolani, A., Graham, L. H., and Savage, A. (2003). The use of low-frequency vocalizations inAfrican elephant (Loxodonta africana) reproductive strategies. Horm. Behav. 43, 433-443. doi:10.1016/S0018-506X(03)00025-4
17. Munro, C., and Stabenfeldt, G. (1984). Development of a microtitre plate enzyme immunoassay for the determination of progesterone. J. Endocrinol. 101, 41-49. doi:10.1677/JOE.0.1010041
18. Ortolani, A., Leong, K., Graham, L., and Savage, A. (2005). Behavioral indices of estrus in a group of captive African elephants (Loxodonta africana). Zoo Biol. 24, 311-329. doi:10.1002/ZOO.20053
19. Peters, A. R. (2005). Veterinary clinical application of GnRH: questions of efficacy.Anim.Reprod.Sci. 88,155-167.doi:10.1016/J.ANIREPROSCI. 2005.05.008
20. Ptaszynska, M. (2006). 'Compendium of Animal Reproduction.' (Intervet International: Boxmeer, The Netherlands.)
21. Purves, R. D. (1992). Optimum numerical integration methods for estimation of area-under-the-curve (AUC) and area-under-the-moment-curve (AUMC). J. Pharmacokinet. Biopharm. 20, 211-226. doi:10.1007/ BF01062525
22. Schulte, B. A., Feldman, E., Lambert, R., Oliver, R., and Oliver, R. (2000). Temporary ovarian inactivity in elephants: relationship to status and time outside. Physiol. Behav. 71, 123-131. doi:10.1016/S0031- 9384(00)00316-4
23. Thitaram, C., Brown,J.L.,Pongsopawijit, P., Chansitthiwet, S.,Wongkalasin, W., et al. (2008). Seasonal effects on the endocrine pattern of semi-captive female Asian elephants (Elephas maximus): timing of the anovulatory luteinizing hormone surge determines the length of the estrous cycle. Theriogenology 69, 237-244. doi:10.1016/ J.THERIOGENOLOGY.2007.09.018
24. Yeh, K. C., and Kwan, K. C. (1978). A comparison of numerical integrating algorithms by trapezoidal, Lagrange, and spline approximation. J. Pharmacokinet. Biopharm. 6, 79-98. doi:10.1007/BF01066064
25. Youngquist, R. S., and Threlfall, W. R. (2007). 'Current Therapy in Large Animal Theriogenology.' (Saunders Elsevier: St Louis.)