Hepatitis C virus compartmentalization and infection recurrence after liver transplantation

American Journal of Transplantation

Volumn 9, Issue 7, 2009, Pages 1591-1601

  Ramirez, S ^a   Perez Del Pulgar, S ^a   Carrion, J A ^a   Costa, J ^a   Gonzalez, P ^a   Massaguer, A ^a   Fondevila, C ^a   Garcia Valdecasas, J C ^a   Navasa, M ^a   Forns, X ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Hepatitis C virus; Hypervariable region 1; Liver transplantation; Quasispecies; Recurrence

Indexed keywords

PEGINTERFERON ALPHA2A; RIBAVIRIN; VIRUS RNA;

ADULT; AGED; ANTIVIRAL THERAPY; ARTICLE; CONTROLLED STUDY; EXPLANT; FEMALE; FOLLOW UP; GENETIC HETEROGENEITY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HYPERVARIABLE REGION 1; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RECURRENT INFECTION; SEQUENCE ANALYSIS; SERUM; TREATMENT RESPONSE; VIRUS GENOME; VIRUS PATHOGENESIS;

ADULT; AGED; AMINO ACID SEQUENCE; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; GENETIC VARIATION; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; LEUKOCYTES, MONONUCLEAR; LIVER; LIVER TRANSPLANTATION; LYMPH NODES; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; RECURRENCE; RNA, VIRAL; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL PROTEINS;

EID: 67649671594     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2009.02666.x     Document Type: Article

References (38)

1. Simmonds P. The origin and evolution of hepatitis viruses in humans. J Gen Virol 2001 82 : 693 712. (Pubitemid 32280027)
2. Martell M, Esteban JI, Quer J et al. Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: Quasispecies nature of HCV genome distribution. J Virol 1992 66 : 3225 3229.
3. Feliu A, Gay E, Garcia-Retortillo M, Saiz JC, Forns X. Evolution of hepatitis C virus quasispecies immediately following liver transplantation. Liver Transpl 2004 10 : 1131 1139. (Pubitemid 39248410)
4. Alter MJ, Margolis HS, Krawczynski K et al. The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team. N Engl J Med 1992 327 : 1899 1905.
5. Berenguer M, Lopez-Labrador FX, Wright TL. Hepatitis C and liver transplantation. J Hepatol 2001 35 : 666 678. (Pubitemid 33078280)
6. Garcia-Retortillo M, Forns X, Feliu A et al. Hepatitis C virus kinetics during and immediately after liver transplantation. Hepatology 2002 35 : 680 687. (Pubitemid 34183974)
7. Forman LM, Lewis JD, Berlin JA, Feldman HI, Lucey MR. The association between hepatitis C infection and survival after orthotopic liver transplantation. Gastroenterology 2002 122 : 889 896. (Pubitemid 34267271)
8. Feray C, Samuel D, Thiers V et al. Reinfection of liver graft by hepatitis C virus after liver transplantation. J Clin Invest 1992 89 : 1361 1365.
9. Dahari H, Feliu A, Garcia-Retortillo M, Forns X, Neumann AU. Second hepatitis C replication compartment indicated by viral dynamics during liver transplantation. J Hepatol 2005 42 : 491 498. (Pubitemid 40342927)
10. Roque-Afonso AM, Ducoulombier D, Di Liberto G et al. Compartmentalization of hepatitis C virus genotypes between plasma and peripheral blood mononuclear cells. J Virol 2005 79 : 6349 6357. (Pubitemid 40617238)
11. Bagaglio S, Cinque P, Racca S et al. Hepatitis C virus populations in the plasma, peripheral blood mononuclear cells and cerebrospinal fluid of HIV/hepatitis C virus-co-infected patients. AIDS 2005 19 (Suppl 3 S151 S165.
12. Blackard JT, Hiasa Y, Smeaton L et al. Compartmentalization of hepatitis C virus (HCV) during HCV/HIV coinfection. J Infect Dis 2007 195 : 1765 1773. (Pubitemid 46870249)
13. Schramm F, Soulier E, Royer C et al. Frequent compartmentalization of hepatitis C virus with leukocyte-related amino acids in the setting of liver transplantation. J Infect Dis 2008 198 : 1656 1666.
14. Lerat H, Rumin S, Habersetzer F et al. In vivo tropism of hepatitis C virus genomic sequences in hematopoietic cells: Influence of viral load, viral genotype, and cell phenotype. Blood 1998 91 : 3841 3849. (Pubitemid 28225753)
15. Pal S, Sullivan DG, Kim S et al. Productive replication of hepatitis C virus in perihepatic lymph nodes in vivo: Implications of HCV lymphotropism. Gastroenterology 2006 130 : 1107 1116.
16. Sansonno D, Iacobelli AR, Cornacchiulo V, Iodice G, Dammacco F. Detection of hepatitis C virus (HCV) proteins by immunofluorescence and HCV RNA genomic sequences by non-isotopic in situ hybridization in bone marrow and peripheral blood mononuclear cells of chronically HCV-infected patients. Clin Exp Immunol 1996 103 : 414 421.
17. Maggi F, Giorgi M, Fornai C et al. Detection and quasispecies analysis of hepatitis C virus in the cerebrospinal fluid of infected patients. J Neurovirol 1999 5 : 319 323. (Pubitemid 29329107)
18. Laskus T, Radkowski M, Wilkinson J, Vargas H, Rakela J. The origin of hepatitis C virus reinfecting transplanted livers: Serum-derived versus peripheral blood mononuclear cell-derived virus. J Infect Dis 2002 185 : 417 421. (Pubitemid 34142802)
19. Carrion JA, Martinez-Bauer E, Crespo G et al. Antiviral therapy increases the risk of bacterial infections in HCV-infected cirrhotic patients awaiting liver transplantation: A retrospective study. J Hepatol 2009 50 : 719 728.
20. Lopez-Labrador FX, Ampurdanes S, Forns X et al. Hepatitis C virus (HCV) genotypes in Spanish patients with HCV infection: Relationship between HCV genotype 1b, cirrhosis and hepatocellular carcinoma. J Hepatol 1997 27 : 959 965. (Pubitemid 27523952)
21. Aiyar A. The use of CLUSTAL W and CLUSTAL X for multiple sequence alignment. Methods Mol Biol 2000 132 : 221 241.
22. Kumar S, Tamura K, Nei M. MEGA: Molecular Evolutionary Genetics Analysis software for microcomputers. Comput Appl Biosci 1994 10 : 189 191. (Pubitemid 24125441)
23. Rozas J, Sanchez-DelBarrio JC, Messeguer X, Rozas R. DnaSP, DNA polymorphism analyses by the coalescent and other methods. Bioinformatics 2003 19 : 2496 2497. (Pubitemid 38016658)
24. Posada D, Crandall KA. MODELTEST: Testing the model of DNA substitution. Bioinformatics 1998 14 : 817 818. (Pubitemid 28552116)
25. Guindon S, Gascuel O. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol 2003 52 : 696 704. (Pubitemid 37365050)
26. Poss M, Rodrigo AG, Gosink JJ et al. Evolution of envelope sequences from the genital tract and peripheral blood of women infected with clade A human immunodeficiency virus type 1. J Virol 1998 72 : 8240 8251. (Pubitemid 28421821)
27. Bonnet E, Van de Peer Y. zt: A sofware tool for simple and partial mantel tests. J Stat Softw 2002 7 : 1 12. (Pubitemid 39217779)
28. Laskus T, Radkowski M, Wang LF, Vargas H, Rakela J. Search for hepatitis C virus extrahepatic replication sites in patients with acquired immunodeficiency syndrome: Specific detection of negative-strand viral RNA in various tissues. Hepatology 1998 28 : 1398 1401. (Pubitemid 28493852)
29. Laskus T, Operskalski EA, Radkowski M et al. Negative-strand hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells from anti-HCV-positive/ HIV-infected women. J Infect Dis 2007 195 : 124 133. (Pubitemid 44958234)
30. Di Liberto G, Roque-Afonso AM, Kara R et al. Clinical and therapeutic implications of hepatitis C virus compartmentalization. Gastroenterology 2006 131 : 76 84. (Pubitemid 44015750)
31. Maggi F, Fornai C, Morrica A et al. Divergent evolution of hepatitis C virus in liver and peripheral blood mononuclear cells of infected patients. J Med Virol 1999 57 : 57 63. (Pubitemid 28553380)
32. Ducoulombier D, Roque-Afonso AM, Di Liberto G et al. Frequent compartmentalization of hepatitis C virus variants in circulating B cells and monocytes. Hepatology 2004 39 : 817 825. (Pubitemid 38337663)
33. Hughes MG, Jr., Rudy CK, Chong TW et al. E2 quasispecies specificity of hepatitis C virus association with allografts immediately after liver transplantation. Liver Transpl 2004 10 : 208 216. (Pubitemid 38240119)
34. Cabot B, Esteban JI, Martell M et al. Structure of replicating hepatitis C virus (HCV) quasispecies in the liver may not be reflected by analysis of circulating HCV virions. J Virol 1997 71 : 1732 1734. (Pubitemid 27030358)
35. Cabot B, Martell M, Esteban JI et al. Nucleotide and amino acid complexity of hepatitis C virus quasispecies in serum and liver. J Virol 2000 74 : 805 811. (Pubitemid 30036216)
36. Fan X, Solomon H, Poulos JE, Neuschwander-Tetri BA, Di Bisceglie AM. Comparison of genetic heterogeneity of hepatitis C viral RNA in liver tissue and serum. Am J Gastroenterol 1999 94 : 1347 1354. (Pubitemid 29214652)
37. Shimizu YK, Igarashi H, Kanematu T et al. Sequence analysis of the hepatitis C virus genome recovered from serum, liver, and peripheral blood mononuclear cells of infected chimpanzees. J Virol 1997 71 : 5769 5773. (Pubitemid 27304911)
38. Fishman SL, Murray JM, Eng FJ, Walewski JL, Morgello S, Branch AD. Molecular and bioinformatic evidence of hepatitis C virus evolution in brain. J Infect Dis 2008 197 : 597 607. (Pubitemid 351321539)