Carbohydrate response element binding protein gene expression is positively regulated by thyroid hormone

Endocrinology

Volumn 150, Issue 7, 2009, Pages 3417-3424

  Hashimoto, Koshi ^a   Ishida, Emi ^a   Matsumoto, Shunichi ^a   Okada, Shuichi ^a   Yamada, Masanobu ^a   Satoh, Teturou ^a   Monden, Tsuyoshi ^b   Mori, Masatomo ^a  

^a GUNMA UNIVERSITY   (Japan)

^b DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN; LIVER X RECEPTOR; MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; C57BL 6 MOUSE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HORMONAL REGULATION; HORMONE BINDING; LIPOGENESIS; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; HUMANS; LIVER; MALE; MICE; MICE, INBRED C57BL; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THYROID HORMONES; TRANSCRIPTION FACTORS; TRIIODOTHYRONINE; UP-REGULATION;

EID: 67649665591     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0059     Document Type: Article

References (53)

1. Oppenheimer JH, Schwartz HL, Mariash CN, Kinlaw WB, Wong NC, Freake HC 1987 Advances in our understanding of thyroid hormone action at the cellular level. Endocr Rev 8:288-308
2. Lazar MA 1993 Thyroid hormone receptors: multiple forms, multiple possibilities. Endocr Rev 14:184-193 (Pubitemid 23118416)
3. Silva JE 2005 Intermediary metabolism and the sympathoadrenal system in hypothyroidism. 9th ed. Philadelphia: Lippincott Williams and Wilkins
4. Duntas LH 2002 Thyroid disease and lipids. Thyroid 12:287-293 (Pubitemid 34438931)
5. O'Brien T, Katz K, Hodge D, Nguyen TT, Kottke BA, Hay ID 1997 The effect of the treatment of hypothyroidism and hyperthyroidism on plasma lipids and apolipoproteins AI, AII and E. Clin Endocrinol (Oxf) 46:17-20
6. Nishitani H, Okamura K, Noguchi S, Inoue K, Morotomi Y, Fujishima M 1990 Serum lipid levels in thyroid dysfunction with special reference to transient elevation during treatment in hyperthyroid Graves' disease. Horm Metab Res 22:490-493 (Pubitemid 20336315)
7. Miura S, Iitaka M, Yoshimura H, Kitahama S, Fukasawa N, Kawakami Y, Sakurai S, Urabe M, Sakatsume Y, Ito K, Ishii J 1994 Disturbed lipid metabolism in patients with subclinical hypothyroidism: effect of L-thyroxine therapy. Intern Med 33:413-417 (Pubitemid 24269857)
8. Pearce EN 2004 Hypothyroidism and dyslipidemia: modern concepts and approaches. Curr Cardiol Rep 6:451-456 (Pubitemid 39585763)
9. Pearce EN, Wilson PW, Yang Q, Vasan RS, Braverman LE 2008 Thyroid function and lipid subparticle sizes in patients with short-term hypothyroidism and a population-based cohort. J Clin Endocrinol Metab 93:888-894
10. Stoeckman AK, Towle HC 2002 The role of SREBP-1c in nutritional regulation of lipogenic enzyme gene expression. J Biol Chem 277:27029-27035 (Pubitemid 34951715)
11. Uyeda K, Repa JJ 2006 Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. Cell Metab 4:107-110 (Pubitemid 44138720)
12. Horton JD, Goldstein JL, Brown MS 2002 SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109:1125-1131 (Pubitemid 34496588)
13. Viguerie N, Millet L, Avizou S, Vidal H, Larrouy D, Langin D 2002 Regulation of human adipocyte gene expression by thyroid hormone. J Clin Endocrinol Metab 87:630-634 (Pubitemid 34158229)
14. Hashimoto K, Yamada M, Matsumoto S, Monden T, Satoh T, Mori M 2006 Mouse sterol response element binding protein-1c gene expression is negatively regulated by thyroid hormone. Endocrinology 147:4292-4302 (Pubitemid 44268380)
15. Yamashita H, Takenoshita M, Sakurai M, Bruick RK, Henzel WJ, Shillinglaw W, Arnot D, Uyeda K 2001 A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Proc Natl Acad Sci USA 98:9116-9121 (Pubitemid 32743878)
16. Iizuka K, Horikawa Y 2008 ChREBP: a glucose-activated transcription factor involved in the development of metabolic syndrome. Endocr J 55:617-624
17. Ishii S, Iizuka K, Miller BC, Uyeda K 2004 Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription. Proc Natl Acad Sci USA 101:15597-15602 (Pubitemid 39473533)
18. Decaux JF, Antoine B, Kahn A 1989 Regulation of the expression of the L-type pyruvate kinase gene in adult rat hepatocytes in primary culture. J Biol Chem 264:11584-11590 (Pubitemid 19185323)
19. Thompson KS, Towle HC 1991 Localization of the carbohydrate response element of the rat L-type pyruvate kinase gene. J Biol Chem 266:8679-8682 (Pubitemid 21906566)
20. da Silva Xavier G, Rutter GA, Diraison F, Andreolas C, Leclerc I 2006 ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic β-cells. J Lipid Res 47:2482-2491
21. Dentin R, Girard J, Postic C 2005 Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver. Biochimie (Paris) 87:81-86
22. Kawaguchi T, Takenoshita M, Kabashima T, Uyeda K 2001 Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein. Proc Natl Acad Sci USA 98:13710-13715 (Pubitemid 33115963)
23. Dentin R, Benhamed F, Pégorier JP, Foufelle F, Viollet B, Vaulont S, Girard J, Postic C 2005 Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation. J Clin Invest 115:2843-2854 (Pubitemid 41434411)
24. Dentin R, Peéorier JP, Benhamed F, Foufelle F, Ferré P, Fauveau V, Magnuson MA, Girard J, Postic C 2004 Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. J Biol Chem 279:20314-20326 (Pubitemid 38623477)
25. Uyeda K, Yamashita H, Kawaguchi T 2002 Carbohydrate responsive element-binding protein (ChREBP): a key regulator of glucose metabolism and fat storage. Biochem Pharmacol 63:2075-2080 (Pubitemid 34756672)
26. Cha JY, Repa JJ 2007 The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR. J Biol Chem 282:743-751 (Pubitemid 47076632)
27. Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ 2001 Nuclear receptors and lipid physiology: opening the X-files. Science 294:1866-1870 (Pubitemid 33101573)
28. Stulnig TM, Steffensen KR, Gao H, Reimers M, Dahlman-Wright K, Schuster GU, Gustafsson JA 2002 Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue. Mol Pharmacol 62:1299-1305 (Pubitemid 35407455)
29. Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P 2003 Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 9:213-219 (Pubitemid 36227724)
30. Berkenstam A, Gustafsson JA 2005 Nuclear receptors and their relevance to diseases related to lipid metabolism. Curr Opin Pharmacol 5:171-176 (Pubitemid 40378749)
31. Zelcer N, Tontonoz P 2006 Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest 116:607-614 (Pubitemid 43326865)
32. Mitro N, Mak PA, Vargas L, Godio C, Hampton E, Molteni V, Kreusch A, Saez E 2007 The nuclear receptor LXR is a glucose sensor. Nature 445:219-223 (Pubitemid 46095727)
33. Umesono K, Murakami KK, Thompson CC, Evans RM 1991 Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell 65:1255-1266 (Pubitemid 121001338)
34. Apfel R, Benbrook D, Lernhardt E, Ortiz MA, Salbert G, Pfahl M 1994 A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily. Mol Cell Biol 14:7025-7035 (Pubitemid 24299771)
35. Teboul M, Enmark E, Li Q, Wikström AC, Pelto-Huikko M, Gustafsson JA 1995 OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor. Proc Natl Acad Sci USA 92:2096-2100
36. Willy PJ, Umesono K, Ong ES, Evans RM, Heyman RA, Mangelsdorf DJ 1995 LXR, a nuclear receptor that defines a distinct retinoid response pathway. Genes Dev 9:1033-1045
37. Quack M, Frank C, Carlberg C 2002 Differential nuclear receptor signalling from DR4-type response elements. J Cell Biochem 86:601-612 (Pubitemid 36076176)
38. Berkenstam A, Färnegårdh M, Gustafsson JA 2004 Convergence of lipid homeostasis through liver X and thyroid hormone receptors. Mech Ageing Dev 125:707-717 (Pubitemid 39485237)
39. Hashimoto K, Cohen RN, Yamada M, Markan KR, Monden T, Satoh T, Mori M, Wondisford FE 2006 Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model. J Biol Chem 281:295-302 (Pubitemid 43671189)
40. Hashimoto K, Matsumoto S, Yamada M, Satoh T, Mori M 2007 Liver X receptor-α gene expression is positively regulated by thyroid hormone. Endocrinology 148:4667-4675 (Pubitemid 47481540)
41. Ren Y, Satoh T, Yamada M, Hashimoto K, Konaka S, Iwasaki T, Mori M 1998 Stimulation of the preprothyrotropin-releasing hormone gene by epidermal growth factor. Endocrinology 139:195-203 (Pubitemid 28166309)
42. Patrone G, Puppo F, Cusano R, Scaranari M, Ceccherini I, Puliti A, Revazzolo R2000 Nuclear run-on assay using biotin labeling, magnetic bead capture and analysis by fluorescence-based RT-PCR. Biotechniques 29:1012-1014, 1016-1017 (Pubitemid 30845836)
43. Schbeler D, Bode J 1997 A sensitive transcription assay based on a simplified nuclear runon protocol. Elsevier Technical Tips Online 2:140-142
44. Madak-Erdogan Z, Kieser KJ, Kim SH, Komm B, Katzenellenbogen JA, Katzenellenbogen BS 2008 Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors. Mol Endocrinol 22:2116-2127
45. Mariash CN, Kaiser FE, Schwartz HL, Towle HC, Oppenheimer JH 1980 Synergism of thyroid hormone and high carbohydrate diet in the induction of lipogenic enzymes in the rat. Mechanisms and implications. J Clin Invest 65:1126-1134 (Pubitemid 10043609)
46. Forciea MA, Schwartz HL, Towle HC, Mariash CN, Kaiser FE, Oppenheimer JH 1981 Thyroid hormone-carbohydrate interaction in the rat: correlation between age-related reductions in the inducibility of hepatic malic enzyme by triiodo-L-thyronine and a high carbohydrate, fat-free diet. J Clin Invest 67:1739-1747 (Pubitemid 11127566)
47. Blennemann B, Moon YK, Freake HC 1992 Tissue-specific regulation of fatty acid synthesis by thyroid hormone. Endocrinology 130:637-643
48. Brown SB, Maloney M, Kinlaw WB 1997 "Spot 14" protein functions at the pretranslational level in the regulation of hepatic metabolism by thyroid hormone and glucose. J Biol Chem 272:2163-2166 (Pubitemid 27058495)
49. Koo SH, Towle HC 2000 Glucose regulation of mouse S(14) gene expression in hepatocytes. Involvement of a novel transcription factor complex. J Biol Chem 275:5200-5207 (Pubitemid 30108924)
50. Denechaud PD, Dentin R, Girard J, Postic C 2008 Role of ChREBP in hepatic steatosis and insulin resistance. FEBS Lett 582:68-73 (Pubitemid 350297238)
51. Heimberg M, Olubadewo JO, Wilcox HG 1985 Plasma lipoproteins and regulation of hepatic metabolism of fatty acids in altered thyroid states. Endocr Rev 6:590-607
52. Abbas JM, Chakraborty J, Akanji AO, Doi SA 2008 Hypothyroidism results in small dense LDL independent of IRS traits and hypertriglyceridemia. Endocr J 55:381-389 (Pubitemid 351670966)
53. Teixeira Pde F, Reuters VS, Ferreira MM, Almeida CP, Reis FA, Buescu A, Costa AJ, Vaisman M 2008 Lipid profile in different degrees of hypothyroidism and effects of levothyroxine replacement in mild thyroid failure. Transl Res 151:224-231