Myocardial perfusion defects in right ventricular apical pacing are caused by partial volume effects because of wall motion abnormalities: A new model to study gated myocardial SPECT with the pacemaker on and off

Nuclear Medicine Communications

Volumn 30, Issue 6, 2009, Pages 480-484

  Ten Cate, Tim J F ^a   Van Hemel, Norbert M ^b   Verzijlbergen, Johan F ^a  

^a ST ANTONIUS HOSPITAL   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Myocardial perfusion single photon emission computed tomography; Pacing; Wall motion

Indexed keywords

METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M;

AGED; ARTICLE; ATRIOVENTRICULAR CONDUCTION; BRADYCARDIA; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; FEMALE; HEART LEFT BUNDLE BRANCH BLOCK; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE BLOOD FLOW; HEART MUSCLE PERFUSION; HEART PACING; HEART PERFORMANCE; HEART VENTRICLE CONDUCTION; HUMAN; MALE; MYOCARDIAL DISEASE; PACEMAKER; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TACHYCARDIA;

AGED; CARDIAC-GATED SINGLE-PHOTON EMISSION COMPUTER-ASSISTED TOMOGRAPHY; CORONARY CIRCULATION; FEMALE; HEART ATRIA; HEART VENTRICLES; HUMANS; MODELS, BIOLOGICAL; MOVEMENT; PACEMAKER, ARTIFICIAL;

EID: 67649661994     PISSN: 01433636     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNM.0b013e32832b9a45     Document Type: Article

References (16)

1. Ten Cate TJ, Visser FC, Panhuyzen-Goedkoop NM, Verzijlbergen JF, van Hemel NM. Pacemaker-related myocardial perfusion defects worsen during higher pacing rate and coronary flow augmentation. Heart Rhythm 2005; 2:1058-1063.
2. Skalidis El, Kochiadakis GE, Koukouraki SI, Chrysostomakis SI, Igoumenidis NE, Karkavitsas NS, ef al. Myocardial perfusion in patients with permanent ventricular pacing and normal coronary arteries. J Am Coll Cardiol 2001; 37:124-129.
3. Tse HF, Lau CP. Long-term effect of right ventricular pacing on myocardial perfusion and function. J Am Coll Cardiol 1997; 29:744-749.
4. Lebtahi NE, Stauffer JC, Delaloye AB. Left bundle branch block and coronary artery disease: accuracy of dipyridamole thallium-201 single-photon emission computed tomography in patients with exercise anteroseptal perfusion defects. J Nucl Cardiol 1997; 4:266-273.
5. Larcos G, Gibbons PJ, Brown ML. Diagnostic accuracy of exercise thallium-201 single-photon emission computed tomography in patients with left bundle branch block. Am J Cardiol 1991; 68:756-760.
6. Rosenbush SW, Ruggie N, Turner DA, Von Behren PL, Denes P, Fordham EW, ef al. Sequence and timing of ventricular wall motion in patients with bundle branch block. Assessment by radionuclide cineangiography. Circulation 1982; 66:1113-1119.
7. Ono S, Nohara R, Kambara H, Okuda K, Kawai C. Regional myocardial perfusion and glucose metabolism in experimental left bundle branch block. Circulation 1992; 85:1125-1131.
8. Prinzen FW, Hunter WC, Wyman BT, McVeigh ER. Mapping of regional myocardial strain and work during ventricular pacing: experimental study using magnetic resonance imaging tagging. J Am Coll Cardiol 1999; 33:1735-1742.
9. McVeigh ER, Prinzen FW, Wyman BT, Tsitlik JE, Halperin HR, Hunter WC. Imaging asynchronous mechanical activation of the paced heart with tagged MRI. Magn Reson Med 1998; 39:507-513.
10. Prinzen FW, Augustijn CH, Arts T, Allessie MA, Reneman RS. Redistribution of myocardial fiber strain and blood flow by asynchronous activation. Am J Physiol 1990; 259:H300-H308.
11. Nowak B, Stellbrink C, Schaefer WM, Sinha AM, Breithardt OA, Kaiser HJ, ef al. Comparison of regional myocardial blood flow and perfusion in dilated cardiomyopathy and left bundle branch block: role of wall thickening. J Nucl Med 2004; 45:414-418.
12. Mahrholdt H, Zhydkov A, Hager S, Meinhardt G, Vogelsberg H, Wagner A, et al. Left ventricular wall motion abnormalities as well as reduced wall thickness can cause false positive results of routine SPECT perfusion imaging for detection of myocardial infarction. Eur Heart J 2005; 26:2127-2135.
13. Hayat SA, Dwivedi G, Jacobsen A, Lim TK, Kinsey C, Senior R. Effects of left bundle-branch block on cardiac structure, function, perfusion, and perfusion reserve: implications for myocardial contrast echocardiography versus radionuclide perfusion imaging for the detection of coronary artery disease. Circulation 2008; 117:1832-1841.
14. Ten Cate TJ, Scheffer MG, Sutherland GR, Verzijlbergen JF, van Hemel NM. Right ventricular outflow and apical pacing comparably worsen the echocardioghraphic normal left ventricle. Eur J Echocardiogr 2008; 9:672-677.
15. Berman DS, Abidov A, Kang X, Hayes SW, Friedman JD, Sciammarella MG, ef al. Prognostic validation of a 17-segment score derived from a 20-segment score for myocardial perfusion SPECT interpretation. J Nucl ' Cardiol 2004; 11:414-423.
16. Jain 0. Technetium-99 m labeled myocardial perfusion imaging agents. Semin Nucl Med 1999; 29:221 -236.