Rapid analysis of tetracaine for a tape stripping pharmacokinetic study using short-end capillary electrophoresis

Biomedical Chromatography

Volumn 23, Issue 5, 2009, Pages 488-491

  Al Otaibi, F ^a   Tucker, A T ^a,b   Johnston, A ^a   Perrett, D ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Capillary electrophoresis; Local anaesthetics; Short end injection; Tape stripping

Indexed keywords

ELECTROLYTES; FUSED SILICA; QUALITY CONTROL; SIGNAL TO NOISE RATIO; WATER INJECTION;

CAPILLARY-ZONE ELECTROPHORESIS; INTERNAL DIAMETERS; LOCAL ANAESTHETIC; PHARMACOKINETIC STUDIES; RAPID ANALYSIS; SHORT-END; SHORT-END INJECTION; SIMPLE++; TAPE STRIPPING; TETRACAINE;

CAPILLARY ELECTROPHORESIS;

METHANOL; PHOSPHORIC ACID; PROCAINE; TETRACAINE; WATER; LOCAL ANESTHETIC AGENT;

ACCURACY; ARTICLE; CALIBRATION; CAPILLARY ZONE ELECTROPHORESIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STABILITY; DRUG STRUCTURE; DRUG TISSUE LEVEL; HUMAN; HUMAN EXPERIMENT; LOCAL ANESTHESIA; NORMAL HUMAN; PH; QUALITY CONTROL; QUANTITATIVE ANALYSIS; ROOM TEMPERATURE; SEPARATION TECHNIQUE; SIGNAL NOISE RATIO; STORAGE TEMPERATURE; VOLUNTEER; CAPILLARY ELECTROPHORESIS; CHEMISTRY; ECONOMICS; METHODOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SKIN; STANDARD; TIME; VALIDATION STUDY;

ANESTHETICS, LOCAL; ELECTROPHORESIS, CAPILLARY; HUMANS; PROCAINE; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SKIN; TETRACAINE; TIME FACTORS;

EID: 67649641749     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1142     Document Type: Article

References (12)

1. Christophe H, Aarti N, Yogeshvar NK, Jonathan H and Richard HG. Dermatopharmacokinetic prediction of topical drug bioavailability in vivo. Journal of Investigative Dermatology 2007; 127: 887-894.
2. FDA. Guidance for Industry: Statistical Approaches to Establishing Bioequivalence. Department of Health and Human Services Center for Drug Evaluation and Research (CDER), 2001.
3. Gilabert LE, Sagrado S, Medina HMJ and Villanueva CRM. Determination of procaine and tetracaine in plasma samples by micellar liquid chromatography and direct injection of sample. Chromatographia 2001; 53: 256-260.
4. Hino Y, Ikeda N, Kudo K and Tsuji A. Sensitive and selective determination of tetracaine and its metabolite in human samples by gas chromatography-mass spectrometry. Journal of Analytical Toxicology 2000; 24: 165-169.
5. ISO 5725:1994. Accuracy (Trueness And Precision) of Measurement Methods and Results. British Standards Institute, 1994.
6. Martindale. The Extra Pharmacopoeia. Royal Pharmaceutical Society of Great Britain: London, 1996.
7. Mazumdar B, Tomlinson AA and Faulder GC. Preliminary study to assay plasma amethocaine concentrations after topical application of a new local anaesthetic cream containing amethocaine. British Journal of Anaesthesia 1991; 67: 432-436.
8. Menon GN and Norris BJ. Simultaneous determination of tetracaine and its degradation product, p-n-butylaminobenzoic acid, by high-performance liquid chromatography. Journal of Pharmaceutical Sciences 1981; 70: 569-570.
9. Robert IE and Albert AK. The spectrophotometric determination of tetracaine and phenylephrine hydrochloride. Journal of the American Pharmaceutical Association 2006; 41: 71-74.
10. Stinchcomb AL, Pirot F, Touraille GD, Bunge AL and Guy RH. Chemical uptake into human stratum corneum in vivo from volatile and nonvolatile solvents. Pharmaceutical Research 1999; 16: 1288-1293.
11. Yang SD, Xue Y, Tian XQ, Jui MC, Xu X and Yu YW. Simultaneous determination of lidocaine, bupivacaine and tetracaine in human plasma by high performance liquid chromatography. Acta Pharmaceutica Sinica 1984; 19: 611-615.
12. Yukiko H, Keiko K, Akiko K and Noriki I. A sudden death following tetracaine-induced spinal anaesthesia. Legal Medicine 2002; 4: 55-59.