Central lateral thalamic neurons receive noxious visceral mechanical and chemical input in rats

Journal of Neurophysiology

Volumn 102, Issue 1, 2009, Pages 244-258

  Ren, Yong ^a   Zhang, Liping ^b   Lu, Ying ^a   Yang, Hong ^a   Westlund High, Karin N ^b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; BRADYKININ; MORPHINE; NALOXONE; PROTEIN C FOS;

ABDOMINAL DISTENSION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENTION; AUTONOMIC NERVOUS SYSTEM FUNCTION; BRAIN STEM; CENTRAL LATERAL NUCLEUS; CONTROLLED STUDY; CORDOTOMY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; ENDOCRINE FUNCTION; MOOD DISORDER; MOTOR PERFORMANCE; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORY NERVE; SENSORY STIMULATION; SPINOTHALAMIC TRACT; SPLANCHNIC NERVE; THALAMUS LATERAL NUCLEUS;

ACTION POTENTIALS; AFFERENT PATHWAYS; ANIMALS; BRADYKININ; MALE; MORPHINE; NEURAL INHIBITION; NEURONS; PAIN; PANCREATIC DUCTS; PHYSICAL STIMULATION; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; THALAMUS; VASODILATOR AGENTS; VISCERA; XANTHENES;

EID: 67649595159     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.90985.2008     Document Type: Article

References (49)

1. Albe-Fessard D, Berkley KJ, Kruger L, Ralston HJ, Willis WD. Diencephalic mechanisms of pain sensations. Brain Res Rev 9: 217-296, 1985.
2. Albe-Fessard D, Boivie J, Grant G, Levante A. Labelling of cells in the medulla oblongata and the spinal cord of the monkey after injections of horseradish peroxidase in the thalamus. Neurosci Lett 1: 75-80, 1975.
3. Al-Chaer ED, Lawand NB, Westlund KN, Willis WD. Visceral nociceptive input into the ventral posterolateral nucleus of the thalamus: a new function for the dorsal column pathway. J Neurophysiol 76: 2661-2674, 1996a. (Pubitemid 26346438)
4. Al-Chaer ED, Lawand NB, Westlund KN, Willis WD. Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway. J Neurophysiol 76: 2675-2690, 1996b. (Pubitemid 26346439)
5. Allen GV, Saper CB, Hurley KM, Cechetto DF. Organization of visceral and limbic connections in the insular cortex of the rat. J Comp Neurol 311: 1-16, 1991.
6. Ammons WS. Primate spinothalamic cell responses to ureteral occlusion. Brain Res 496: 124-130, 1989. (Pubitemid 19212352)
7. Apkarian AV, Hodge CJ. Primate spinothalamic pathways: III. Thalamic terminations of the dorsolateral and ventral spinothalamic pathways. J Comp Neurol 288: 493-511, 1989. (Pubitemid 19247622)
8. Becker R, Sure U, Bertalanffy H. Punctate midline myelotomy. A new approach in the management of visceral pain. Acta Neurochir (Wien) 141: 881-883, 1999. (Pubitemid 29408431)
9. Berendse HW, Groenewegen HJ. Organization of the thalamostriatal projections in the rat, with special emphasis on the ventral striatum. J Comp Neurol 299: 187-228, 1990. (Pubitemid 20313479)
10. Berkley KJ, Benoist J-M, Gautron M, Guilbaud G. Responses of neurons in the caudal intralaminar thalamic complex of the rat to stimulation of the uterus, vagina, cervix, colon, and skin. Brain Res 695: 92-95, 1995.
11. Bullitt E. Expression of c-fos-like protein as a marker for neuronal activity following noxious stimulation in the rat. J Comp Neurol 296: 517-530, 1990. (Pubitemid 20191460)
12. Bushnell MC, Duncan GH. Sensory and affective aspects of pain perception: is medial thalamus restricted to emotional issues? Exp Brain Res 78: 415-418, 1989. (Pubitemid 20011768)
13. Carstens E, Leah J, Lechner J, Zimmermann M. Demonstration of extensive brainstem projections to medial and lateral thalamus and hypothalamus in the rat. Neuroscience 35: 609-626, 1990. (Pubitemid 20198394)
14. Craig AD, Burton H. The distribution and topographical organization in the thalamus of anterogradely transported horseradish peroxidase after spinal injections in cat and raccoon. Exp Brain Res 58: 227-254, 1985. Deschênes M, Bourassa J, Parent A. Striatal and cortical projections of single neurons from the central lateral thalamic nucleus in the rat, Neuroscience 72: 679-687, 1996. (Pubitemid 15114561)
15. Dong WK, Ryu H, Wagman IH. Nociceptive responses of neurons in medial thalamus and their relationship to spinothalamic pathways. J Neurophysiol 41: 1592-1613, 1978. (Pubitemid 9061323)
16. Dostrovsky JO, Guilbaud G. Nociceptive responses in medial thalamus of the normal and arthritic rat. Pain 40: 93-104, 1990. (Pubitemid 20038542)
17. Gebhart GF. Opiate and opioid peptide effects on brainstem neurons: relevance to nociception and antinociceptive mechanisms. Pain 12: 93-140, 1982. (Pubitemid 12177704)
18. Gildenberg PL, Hirshberg RM. Limited myelotomy for the treatment of intractable cancer pain. J Neurol Neurosurg Psychiatry 47: 94-96, 1984. (Pubitemid 14154248)
19. Guilbaud G, Bernard JF, Benoist JM. Brain areas involved in nociception and pain. In: Textbook of Pain (3rd ed.), edited by Wall PD, Melzack R. New York: Churchill Livingstone,1994, p. 113-128.
20. Hancock MB, Foreman RD, Willis WD. Convergence of visceral and cutaneous input onto spinothalamic tract cells in the thoracic spinal cord of the cat. Exp Neurol 47: 240-248, 1975.
21. Hirshberg RM, Al-Chaer ED, Lawand NB, Westlund KN, Willis WD. Is there a pathway in the dorsal funiculus that signals visceral pain? Pain 67: 291-305, 1996. (Pubitemid 26375345)
22. Honda CN. Visceral and somatic afferent convergence onto neurons near the central canal in the sacral spinal cord of cat. J Neurophysiol 53: 1059-1078, 1985. (Pubitemid 15085387)
23. Honda CN, Perl ER. Functional and morphological features of neurons in the midline region of the caudal spinal cord of the cat. Brain Res 340: 285-295, 1985. (Pubitemid 15226707)
24. Houghton A, Wang C-C, Westlund KN. Do nociceptive signals from the pancreas travel in the dorsal column? Pain 89: 207-220, 2001. (Pubitemid 32146400)
25. Hu Y, Li Y. PMM for severe visceral pain treatment in patients with advanced visceral cancer (in Chinese). Natl Med J China 82: 856-857, 2002.
26. Hwang SL, Lin CL, Lieu AS, Kuo TH, Yu KL, Ou-Yang F, Wang SN, Lee KT, Howng SL. Punctate midline myelotomy for intractable visceral pain caused by hepatobiliary or pancreatic cancer. J Pain Symptom Manage 27: 79-84, 2004. (Pubitemid 38050251)
27. Jones EG. The Intralaminar Nuclei. In: The Thalamus. New York: Plenum, 1985, chapt. 12, p. 607-645.
28. Kamishina H, Yurcisin GH, Corwin JV, Reep RL. Striatal projections from the rat lateral posterior thalamic nucleus. Brain Res 1204: 24-39, 2008.
29. Lu Y, Vera-Portocarrero LP, Westlund KN. Intrathecal coadministration of D-APV and morphine is maximally effective in a rat experimental pancreatitis model. Anesthesiology 98: 734-740, 2003. (Pubitemid 36262603)
30. Mehler WR. The posterior thalamic region in man. Confin Neurol 27: 18-29, 1966.
31. Milne RJ, Foreman RD, Giesler GJ Jr, Willis WD. Convergence of cutaneous and pelvic visceral nociceptive inputs onto primate spinothalamic neurons. Pain 11: 163-183, 1981. (Pubitemid 12232010)
32. Moore RY, Halaris AE, Jones BE. Serotonin neurons of the midbrain raphe: ascending projections. J Comp Neurol 180: 417-438, 1978. (Pubitemid 8377346)
33. Nauta HJ, Soukup VM, Fabian RH, Lin JT, Grady JJ, Williams CG, Campbell GA, Westlund KN, Willis WD Jr. Punctate midline myelotomy for the relief of visceral cancer pain. J Neurosurg 92: 125-130, 2000. (Pubitemid 30207405)
34. Ness TJ, Gebhart GF. Characterization of neuronal responses to noxious visceral and somatic stimuli in the medial lumbosacral spinal cord of the rat. J Neurophysiol 5: 1867-1892, 1987. (Pubitemid 17090139)
35. Ness TJ, Gebhart GF. Colorectal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudoaffective reflexes in the rat. Brain Res 450: 153-169, 1988. (Pubitemid 18135443)
36. Ness TJ, Randich A, Gebhart GF. Further behavioral evidence that colorectal distension is a "noxious" visceral stimulus in rats. Neurosci Lett 131: 113-116, 1991.
37. Olivar T, Cervero F, Laird JM. Responses of rat spinal neurons to natural and electrical stimulation of colonic afferents: effect of inflammation. Brain Res 866: 168-177, 2000. (Pubitemid 30313019)
38. Palecek J, Paleckova V, Willis WD. The roles of pathways in the spinal cord lateral and dorsal funiculi in signaling nociceptive somatic and visceral stimuli in rats. Pain 96: 297-307, 2002. (Pubitemid 34327876)
39. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates (2nd ed.). New York: Academic Press, 1986.
40. Peschanski M, Guilbaud M, Gautron M. Posterior intralaminar region in the rat: neuronal responses to noxious and non-noxious cutaneous stimuli. Exp Neurol 72: 226-238, 1981. (Pubitemid 11152816)
41. Reep RL, Corwin JV, Hashimoto A, Watson RT. Afferent connections of medial precentral cortex in the rat. Neurosci Lett 44: 247-252, 1984. (Pubitemid 14128758)
42. Ren Y, Lu Y, Yang H, Westlund KN. Responses of neurons in central lateral thalamic nucleus to visceral stimulation in rats. Soc Neurosci Abstr 346.8, 2006.
43. Smith Y, Raju DV, Paré J-F, Sidibe M. The thalamostriatal system: a highly specific network of the basal ganglia circuitry. Trends Neurosci 27: 520-527, 2004. (Pubitemid 39149820)
44. Van der Werf YD, Witter MP, Groenewegen HJ. The intralaminar and midline nuclei of the thalamus. Anatomical and functional evidence for participation in processes of arousal and awareness. Brain Res Rev 39: 107-140, 2002. (Pubitemid 35341095)
45. Wang CC, Westlund KN. Responses of rat dorsal column neurons to pancreatic nociceptive stimulation. Neuroreport 12: 2527-2530, 2001. (Pubitemid 32682215)
46. Wang CC, Willis WD, Westlund KN. Ascending projections from the area around the spinal cord central canal: a phaseolus Vulgaris leucoagglutinin study in rats. J Comp Neurol 415: 341-367, 1999.
47. Westlund KN, Vera-Portocarrero LP, Zhang L, Wei J, Quast MJ, Cleeland CS. fMRI of supraspinal areas after morphine and one week pancreatic inflammation in rats. Neuroimage 44: 23-34, 2009.
48. Willis WD, Al-Chaer ED, Quast MJ, Westlund KN. A visceral pain pathway in the dorsal column of the spinal cord. Proc Natl Acad Sci USA 96: 7675-7679, 1999. (Pubitemid 29328339)
49. Zhang LP, Chu R, Westlund KN. Responses of rat central lateral thalamic neurons to visceral stimulation. Soc Neurosci Abstr 746.2, 2004.