High-level biosynthesis of the anteiso-C17 isoform of the antibiotic mycosubtilin in Bacillus subtilis and characterization of its candidacidal activity

Applied and Environmental Microbiology

Volumn 75, Issue 13, 2009, Pages 4636-4640

  Fickers, Patrick ^a   Guez, Jean Sébastien ^b   Damblon, Christian ^a   Leclère, Valérie ^b   Béchet, Max ^b   Jacques, Philippe ^b   Joris, Bernard ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b Cité scientifique   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-FUNGAL ACTIVITY; ANTIFUNGAL AGENTS; BACILLUS SUBTILIS; BACILLUS SUBTILIS STRAINS; CANDIDA; CELL LEAKAGE; HIGH-LEVEL PRODUCTION; ISOFORM; LIPOPEPTIDE; THERAPEUTIC USE;

BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; CELL CULTURE;

BACTERIOLOGY;

AMPHOTERICIN B; ANTIBIOTIC AGENT; FLUCONAZOLE; GENOMIC DNA; MYCOSUBTILIN; VALINOMYCIN;

ANTIMICROBIAL ACTIVITY; BACTERIUM; BIOASSAY; DISEASE TREATMENT; FATTY ACID; FLUOROMETRY; GENETIC ENGINEERING; PEPTIDE; YEAST;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS; BACILLUS SUBTILIS; BACTERIUM CULTURE; BIOSYNTHESIS; CANDIDA; CARBON NUCLEAR MAGNETIC RESONANCE; CRYPTOCOCCUS NEOFORMANS; GENETIC ENGINEERING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PICHIA PASTORIS; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SACCHAROMYCES CEREVISIAE; STRUCTURE ANALYSIS; YARROWIA LIPOLYTICA; YEAST;

ANTIBIOTICS, ANTIFUNGAL; BACILLUS SUBTILIS; BIOSYNTHETIC PATHWAYS; CANDIDA; GENES, BACTERIAL; GENETIC ENGINEERING; LIPOPROTEINS; MICROBIAL SENSITIVITY TESTS; PROTEIN ISOFORMS;

BACILLUS SUBTILIS; CANDIDA;

EID: 67649588280     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00548-09     Document Type: Article

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