A single mutation induces molten globule formation and a drastic destabilization of wild-type cytochrome c at pH 6.0

Journal of Biological Inorganic Chemistry

Volumn 14, Issue 5, 2009, Pages 751-760

  Khurshid Alam Khan, Md ^a   Das, Utpal ^b   Hamidur Rahaman, Md ^a   Imtaiyaz Hassan, Md ^a   Srinivasan, A ^b   Singh, Tej P ^b   Ahmad, Faizan ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Cytochrome c; Molten globule; Pre molten globule; Site directed mutagenesis; Thermal stability

Indexed keywords

8 ANILINO 1 NAPHTHALENESULFONIC ACID; ALANINE; CYTOCHROME C; GLYCINE; HEME; LEUCINE; PHENYLALANINE; SODIUM CHLORIDE; TRYPTOPHAN; TYROSINE; VALINE;

AMINO ACID SEQUENCE; ARTICLE; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; DENATURATION; ENZYME STABILITY; FLUORESCENCE; LIGHT SCATTERING; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; THERMOSTABILITY; ULTRAVIOLET RADIATION;

ANIMALS; CIRCULAR DICHROISM; CYTOCHROME C GROUP; ENZYME STABILITY; HORSES; LIGHT; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN DENATURATION; SCATTERING, RADIATION; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY; TEMPERATURE;

EQUIDAE;

EID: 67649529020     PISSN: 09498257     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00775-009-0488-6     Document Type: Article

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