메뉴 건너뛰기




Volumn 84, Issue , 2007, Pages 93-120

Monoamine oxidase A and B inhibitors in Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords


EID: 67649513919     PISSN: 00729752     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0072-9752(07)84034-6     Document Type: Chapter
Times cited : (18)

References (180)
  • 1
    • 7044245505 scopus 로고    scopus 로고
    • Cardiovascular activity of rasagiline, a selective and potent inhibitor of mitochondrial monoamine oxidase B: comparison with selegiline
    • Abassi Z.A., Binah O., and Youdim M.B. Cardiovascular activity of rasagiline, a selective and potent inhibitor of mitochondrial monoamine oxidase B: comparison with selegiline. Br J Pharmacol 143 3 (2004) 371-378
    • (2004) Br J Pharmacol , vol.143 , Issue.3 , pp. 371-378
    • Abassi, Z.A.1    Binah, O.2    Youdim, M.B.3
  • 2
    • 0019177562 scopus 로고
    • Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type
    • Adolfsson R., Gottfries C.G., Oreland L., et al. Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type. Life Sci 27 (1980) 1029-1034
    • (1980) Life Sci , vol.27 , pp. 1029-1034
    • Adolfsson, R.1    Gottfries, C.G.2    Oreland, L.3
  • 3
    • 0037189081 scopus 로고    scopus 로고
    • An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells
    • Akao Y., Maruyama W., Yi H., et al. An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells. Neurosci Lett 326 2 (2002) 105-108
    • (2002) Neurosci Lett , vol.326 , Issue.2 , pp. 105-108
    • Akao, Y.1    Maruyama, W.2    Yi, H.3
  • 4
    • 0036677312 scopus 로고    scopus 로고
    • Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)-aminoindan
    • Akao Y., Maruyama W., Shimizu S., et al. Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)-aminoindan. J Neurochem 82 4 (2002) 913-923
    • (2002) J Neurochem , vol.82 , Issue.4 , pp. 913-923
    • Akao, Y.1    Maruyama, W.2    Shimizu, S.3
  • 5
    • 0027524961 scopus 로고
    • Symptomatic effect of selegiline in de novo parkinsonian patients. The French Selegiline Multicenter Trial
    • Allain H., Pollak P., and Neukirch H.C. Symptomatic effect of selegiline in de novo parkinsonian patients. The French Selegiline Multicenter Trial. Mov Disord 8 Suppl 1 (1993) 36-40
    • (1993) Mov Disord , vol.8 , Issue.SUPPL. 1 , pp. 36-40
    • Allain, H.1    Pollak, P.2    Neukirch, H.C.3
  • 6
    • 0032609787 scopus 로고    scopus 로고
    • Moclobemide in patients with dementia and depression
    • Amrein R., Martin J.R., and Cameron A.M. Moclobemide in patients with dementia and depression. Adv Neurol 80 (1999) 509-519
    • (1999) Adv Neurol , vol.80 , pp. 509-519
    • Amrein, R.1    Martin, J.R.2    Cameron, A.M.3
  • 7
    • 0029096251 scopus 로고
    • Moclobemide and tricyclic antidepressants in severe depression: meta analysis and prospective studies
    • Angst J., Amrein R., and Stabl M. Moclobemide and tricyclic antidepressants in severe depression: meta analysis and prospective studies. J Clin Psychopharmacol 15 (1995) 16S-23S
    • (1995) J Clin Psychopharmacol , vol.15
    • Angst, J.1    Amrein, R.2    Stabl, M.3
  • 8
    • 2642529309 scopus 로고    scopus 로고
    • Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo
    • Bar-Am O., Yogev-Falach M., Amit T., et al. Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo. J Neurochem 89 5 (2004) 1119-1125
    • (2004) J Neurochem , vol.89 , Issue.5 , pp. 1119-1125
    • Bar-Am, O.1    Yogev-Falach, M.2    Amit, T.3
  • 9
    • 1542317394 scopus 로고    scopus 로고
    • Contrasting neuroprotective and neurotoxic actions of respective metabolites of anti-Parkinson drugs rasagiline and selegiline
    • Bar-Am O., Amit T., and Youdim M.B. Contrasting neuroprotective and neurotoxic actions of respective metabolites of anti-Parkinson drugs rasagiline and selegiline. Neurosci Lett 355 3 (2004) 169-172
    • (2004) Neurosci Lett , vol.355 , Issue.3 , pp. 169-172
    • Bar-Am, O.1    Amit, T.2    Youdim, M.B.3
  • 10
    • 27744486071 scopus 로고    scopus 로고
    • Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine
    • Bar-Am O., Weinreb O., Amit T., et al. Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine. FASEB J 19 13 (2005) 1899-1901
    • (2005) FASEB J , vol.19 , Issue.13 , pp. 1899-1901
    • Bar-Am, O.1    Weinreb, O.2    Amit, T.3
  • 11
    • 0037330729 scopus 로고    scopus 로고
    • Diffuse Lewy body disease-a clinical syndrome or a disease entity?
    • Benecke R. Diffuse Lewy body disease-a clinical syndrome or a disease entity?. J Neurol 250 Suppl 1 (2003) I39-I42
    • (2003) J Neurol , vol.250 , Issue.SUPPL. 1
    • Benecke, R.1
  • 12
    • 0027289608 scopus 로고
    • L-deprenyl increases GFAP immunoreactivity selectively in inactivated astrocytes in rat brain
    • Biagini G., Zoll M., Fuxe K., et al. L-deprenyl increases GFAP immunoreactivity selectively in inactivated astrocytes in rat brain. Neuroreport 5 (1993) 955-958
    • (1993) Neuroreport , vol.5 , pp. 955-958
    • Biagini, G.1    Zoll, M.2    Fuxe, K.3
  • 13
    • 0028343249 scopus 로고
    • The concept of astrocyte-kinetic drug in the treatment of neurodegenerative diseases: evidence for L-deprenyl-induced activation of reactive astrocytes
    • Biagini G., Frasoldati A., Fuxe K., et al. The concept of astrocyte-kinetic drug in the treatment of neurodegenerative diseases: evidence for L-deprenyl-induced activation of reactive astrocytes. Neurochem Int 25 (1994) 17-22
    • (1994) Neurochem Int , vol.25 , pp. 17-22
    • Biagini, G.1    Frasoldati, A.2    Fuxe, K.3
  • 14
    • 6444237189 scopus 로고    scopus 로고
    • The serotonin syndrome
    • Bijl D. The serotonin syndrome. Neth J Med 62 9 (2004) 309-313
    • (2004) Neth J Med , vol.62 , Issue.9 , pp. 309-313
    • Bijl, D.1
  • 15
    • 0016414699 scopus 로고
    • The potentiation of the anti akinetic effect after L-dopa treatment by an inhibitor of MAO-B, Deprenil
    • Birkmayer W., Riederer P., Youdim M.B., et al. The potentiation of the anti akinetic effect after L-dopa treatment by an inhibitor of MAO-B, Deprenil. J Neural Transm 36 (1975) 303-326
    • (1975) J Neural Transm , vol.36 , pp. 303-326
    • Birkmayer, W.1    Riederer, P.2    Youdim, M.B.3
  • 16
    • 0017345412 scopus 로고
    • Implications of combined treatment with 'Madopar' and L-deprenil in Parkinson's disease. A long-term study
    • Birkmayer W., Riederer P., Ambrozi L., et al. Implications of combined treatment with 'Madopar' and L-deprenil in Parkinson's disease. A long-term study. Lancet 1 (1977) 439-443
    • (1977) Lancet , vol.1 , pp. 439-443
    • Birkmayer, W.1    Riederer, P.2    Ambrozi, L.3
  • 17
    • 0022365018 scopus 로고
    • Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study
    • Birkmayer W., Knoll J., Riederer P., et al. Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study. J Neural Transm 64 2 (1985) 113-127
    • (1985) J Neural Transm , vol.64 , Issue.2 , pp. 113-127
    • Birkmayer, W.1    Knoll, J.2    Riederer, P.3
  • 18
    • 2342547676 scopus 로고    scopus 로고
    • Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease
    • Blandini F., Armentero M.T., Fancellu R., et al. Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease. Exp Neurol 187 2 (2004) 455-459
    • (2004) Exp Neurol , vol.187 , Issue.2 , pp. 455-459
    • Blandini, F.1    Armentero, M.T.2    Fancellu, R.3
  • 19
    • 0029417080 scopus 로고    scopus 로고
    • Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer' and de novo Parkinson's disease patients
    • Blum-Degen D., Müller T., Kuhn W., et al. Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer' and de novo Parkinson's disease patients. Neurosci Lett 202 (1996) 17-20
    • (1996) Neurosci Lett , vol.202 , pp. 17-20
    • Blum-Degen, D.1    Müller, T.2    Kuhn, W.3
  • 20
    • 13844252137 scopus 로고    scopus 로고
    • Characterization of the neuroprotective activity of rasagiline in cerebellar granule cells
    • Bonneh-Barkay D., Ziv N., and Finberg J.P. Characterization of the neuroprotective activity of rasagiline in cerebellar granule cells. Neuropharmacology 48 3 (2005) 406-416
    • (2005) Neuropharmacology , vol.48 , Issue.3 , pp. 406-416
    • Bonneh-Barkay, D.1    Ziv, N.2    Finberg, J.P.3
  • 21
    • 0025583426 scopus 로고
    • Kinetic evaluation of MAO-B-activity following oral administration of selegiline and desmethyl-selegiline in rat
    • Borbe H.O., Niebch G., and Nickel B. Kinetic evaluation of MAO-B-activity following oral administration of selegiline and desmethyl-selegiline in rat. J Neural Transm Suppl 32 (1990) 131-137
    • (1990) J Neural Transm Suppl , vol.32 , pp. 131-137
    • Borbe, H.O.1    Niebch, G.2    Nickel, B.3
  • 22
    • 2942689404 scopus 로고    scopus 로고
    • Psychotic symptoms in Parkinson's disease: pathophysiology and management
    • Bosboom J.L., and Wolters E. Psychotic symptoms in Parkinson's disease: pathophysiology and management. Expert Opin Drug Saf 3 3 (2004) 209-220
    • (2004) Expert Opin Drug Saf , vol.3 , Issue.3 , pp. 209-220
    • Bosboom, J.L.1    Wolters, E.2
  • 23
    • 0021940046 scopus 로고
    • Platelet monoamine oxidase activity: demographic characteristics contribute to enzyme activity variability
    • Bridge T.P., Soldo B.J., Phelps B.H., et al. Platelet monoamine oxidase activity: demographic characteristics contribute to enzyme activity variability. J Gerontol 40 (1985) 23-28
    • (1985) J Gerontol , vol.40 , pp. 23-28
    • Bridge, T.P.1    Soldo, B.J.2    Phelps, B.H.3
  • 24
    • 0037507200 scopus 로고    scopus 로고
    • Potential cognitive actions of (n-propargly-(3r)-aminoindan-5-yl)-ethyl, methyl carbamate (tv3326), a novel neuroprotective agent, as assessed in old rhesus monkeys in their performance of versions of a delayed matching task
    • Buccafusco J.J., Terry A.J., Goren Jr. A.V., et al. Potential cognitive actions of (n-propargly-(3r)-aminoindan-5-yl)-ethyl, methyl carbamate (tv3326), a novel neuroprotective agent, as assessed in old rhesus monkeys in their performance of versions of a delayed matching task. Neuroscience 119 3 (2003) 669-678
    • (2003) Neuroscience , vol.119 , Issue.3 , pp. 669-678
    • Buccafusco, J.J.1    Terry, A.J.2    Goren Jr., A.V.3
  • 25
    • 0028943869 scopus 로고
    • (-)-Deprenyl increases the survival of rat retinal ganglion cells after optic nerve crush
    • Buys Y.M., Trope G.E., and Tatton W.G. (-)-Deprenyl increases the survival of rat retinal ganglion cells after optic nerve crush. Curr Eye Res 14 (1995) 119-126
    • (1995) Curr Eye Res , vol.14 , pp. 119-126
    • Buys, Y.M.1    Trope, G.E.2    Tatton, W.G.3
  • 26
    • 0026520063 scopus 로고
    • The new generation of monoamine oxidase inhibitors
    • Cesura A.M., and Pletscher A. The new generation of monoamine oxidase inhibitors. Prog Drug Res 38 (1992) 171-297
    • (1992) Prog Drug Res , vol.38 , pp. 171-297
    • Cesura, A.M.1    Pletscher, A.2
  • 27
    • 0026586150 scopus 로고
    • Depression and senile dementia of Alzheimer's type: a role for moclobemide
    • Chan-Palay V. Depression and senile dementia of Alzheimer's type: a role for moclobemide. Psychopharmacology 106 (1992) S137-S139
    • (1992) Psychopharmacology , vol.106
    • Chan-Palay, V.1
  • 28
    • 0030879210 scopus 로고    scopus 로고
    • Autonomic effects of selegiline: possible cardiovascular toxicity in Parkinson's disease
    • Churchyard A., Mathias C.J., Boonkongchuen P., et al. Autonomic effects of selegiline: possible cardiovascular toxicity in Parkinson's disease. J Neurol Neurosurg Psychiatry 63 2 (1997) 228-234
    • (1997) J Neurol Neurosurg Psychiatry , vol.63 , Issue.2 , pp. 228-234
    • Churchyard, A.1    Mathias, C.J.2    Boonkongchuen, P.3
  • 29
    • 0344758978 scopus 로고    scopus 로고
    • A new low-dose formulation of selegiline: clinical efficacy, patient preference and selectivity for MAO-B inhibition
    • Clarke A., Johnson E.S., Mallard N., et al. A new low-dose formulation of selegiline: clinical efficacy, patient preference and selectivity for MAO-B inhibition. J Neural Transm 110 11 (2003) 1257-1271
    • (2003) J Neural Transm , vol.110 , Issue.11 , pp. 1257-1271
    • Clarke, A.1    Johnson, E.S.2    Mallard, N.3
  • 30
    • 0345189359 scopus 로고    scopus 로고
    • A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition
    • Clarke A., Brewer F., Johnson E.S., et al. A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition. J Neural Transm 110 11 (2003) 1241-1255
    • (2003) J Neural Transm , vol.110 , Issue.11 , pp. 1241-1255
    • Clarke, A.1    Brewer, F.2    Johnson, E.S.3
  • 31
    • 0014965307 scopus 로고
    • Multiple forms of human brain mitochondrial monoamine oxidase
    • Collins G.G., Sandler M., Williams E.D., et al. Multiple forms of human brain mitochondrial monoamine oxidase. Nature 225 (1970) 817-820
    • (1970) Nature , vol.225 , pp. 817-820
    • Collins, G.G.1    Sandler, M.2    Williams, E.D.3
  • 32
    • 0011832918 scopus 로고
    • Ro 11-1163, a specific short acting MAO inhibitor with antidepressant properties
    • Excerpta Medica, Amsterdam
    • Da Prada M., Keller H., Keller R., et al. Ro 11-1163, a specific short acting MAO inhibitor with antidepressant properties. Monoamine Oxidase. Basic and Clinical Frontiers (1981), Excerpta Medica, Amsterdam 183-196
    • (1981) Monoamine Oxidase. Basic and Clinical Frontiers , pp. 183-196
    • Da Prada, M.1    Keller, H.2    Keller, R.3
  • 33
    • 0023797315 scopus 로고
    • On tyramine, food beverages and reversible MAO inhibitor moclobemide
    • Da Prada M., Zürcher G., Wuthrich I., et al. On tyramine, food beverages and reversible MAO inhibitor moclobemide. J Neural Transm Suppl 26 (1988) 31-56
    • (1988) J Neural Transm Suppl , vol.26 , pp. 31-56
    • Da Prada, M.1    Zürcher, G.2    Wuthrich, I.3
  • 34
    • 22244478082 scopus 로고    scopus 로고
    • Neuroprotective effect of rasagiline, a monoamine oxidase-B inhibitor, on spontaneous cell degeneration in a rat model
    • Eliash S., Shteter N., and Eilam R. Neuroprotective effect of rasagiline, a monoamine oxidase-B inhibitor, on spontaneous cell degeneration in a rat model. J Neural Transm 112 8 (2005) 991-1003
    • (2005) J Neural Transm , vol.112 , Issue.8 , pp. 991-1003
    • Eliash, S.1    Shteter, N.2    Eilam, R.3
  • 35
    • 67649474102 scopus 로고    scopus 로고
    • Severe therapy refractory depression as initial mainstream of Parkinson's disease
    • Erfurth A.B., and Back T. Severe therapy refractory depression as initial mainstream of Parkinson's disease. Psychiatr Prax 26 (1999) 46-47
    • (1999) Psychiatr Prax , vol.26 , pp. 46-47
    • Erfurth, A.B.1    Back, T.2
  • 36
    • 0019944455 scopus 로고
    • Relationship between tyramine potentiation and selective inhibition of monoamine oxidase types A and B in the rat vas deferens
    • Finberg J.P., and Tenne M. Relationship between tyramine potentiation and selective inhibition of monoamine oxidase types A and B in the rat vas deferens. Br J Pharmacol 77 1 (1982) 13-21
    • (1982) Br J Pharmacol , vol.77 , Issue.1 , pp. 13-21
    • Finberg, J.P.1    Tenne, M.2
  • 37
    • 0036914093 scopus 로고    scopus 로고
    • Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours
    • Finberg J.P., and Youdim M.B. Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours. Neuropharmacology 43 7 (2002) 1110-1118
    • (2002) Neuropharmacology , vol.43 , Issue.7 , pp. 1110-1118
    • Finberg, J.P.1    Youdim, M.B.2
  • 38
    • 0019462668 scopus 로고
    • Tyramine antagonistic properties of AGN 1135, and irreversible inhibitor of monoamine oxidase type B
    • Finberg J.P., Tenne M., and Youdim M.B. Tyramine antagonistic properties of AGN 1135, and irreversible inhibitor of monoamine oxidase type B. Br J Pharmacol 73 (1981) 65-74
    • (1981) Br J Pharmacol , vol.73 , pp. 65-74
    • Finberg, J.P.1    Tenne, M.2    Youdim, M.B.3
  • 40
    • 0031596702 scopus 로고    scopus 로고
    • Increased striatal dopamine production from L-DOPA following selective inhibition of monoamine oxidase B by R(+)-N-propargyl-1-aminoindan (rasagiline) in the monkey
    • Finberg J.P., Wang J., Bankiewicz K., et al. Increased striatal dopamine production from L-DOPA following selective inhibition of monoamine oxidase B by R(+)-N-propargyl-1-aminoindan (rasagiline) in the monkey. J Neural Transm Suppl 52 (1998) 279-285
    • (1998) J Neural Transm Suppl , vol.52 , pp. 279-285
    • Finberg, J.P.1    Wang, J.2    Bankiewicz, K.3
  • 41
    • 0032498811 scopus 로고    scopus 로고
    • Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor
    • Finberg J.P., Takeshima T., Johnston J.M., et al. Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor. Neuroreport 9 (1998) 703-707
    • (1998) Neuroreport , vol.9 , pp. 703-707
    • Finberg, J.P.1    Takeshima, T.2    Johnston, J.M.3
  • 42
    • 0032609072 scopus 로고    scopus 로고
    • Pharmacology of rasagiline (N-propargyl-1R-aminoindan)
    • Finberg J.P., Lamensdorf I., Weinstock M., et al. Pharmacology of rasagiline (N-propargyl-1R-aminoindan). Adv Neurol 80 (1999) 495-499
    • (1999) Adv Neurol , vol.80 , pp. 495-499
    • Finberg, J.P.1    Lamensdorf, I.2    Weinstock, M.3
  • 43
    • 0025171524 scopus 로고
    • Protection against DSP-4-induced neurotoxicity by deprenyl is not related to its inhibition of MAO B
    • Finnegan K.T., Skratt J.J., Irwin I., et al. Protection against DSP-4-induced neurotoxicity by deprenyl is not related to its inhibition of MAO B. Eur J Pharmacol 184 (1990) 119-126
    • (1990) Eur J Pharmacol , vol.184 , pp. 119-126
    • Finnegan, K.T.1    Skratt, J.J.2    Irwin, I.3
  • 44
    • 0033991079 scopus 로고    scopus 로고
    • MAO-B inhibitors: multiple roles in the therapy of neurodegenerative disorders?
    • Foley P., Gerlach M., Youdim M.B.H., et al. MAO-B inhibitors: multiple roles in the therapy of neurodegenerative disorders?. Parkinsonism Rel Disord 6 1 (2000) 2547
    • (2000) Parkinsonism Rel Disord , vol.6 , Issue.1 , pp. 2547
    • Foley, P.1    Gerlach, M.2    Youdim, M.B.H.3
  • 45
    • 0018880970 scopus 로고
    • Titration of human brain monoamine oxidase -A and -B by clorgyline and L-deprenil
    • Fowler C.J., Oreland L., Marcusson J., et al. Titration of human brain monoamine oxidase -A and -B by clorgyline and L-deprenil. Naunyn Schmiedebergs Arch Pharmacol 311 (1980) 263-272
    • (1980) Naunyn Schmiedebergs Arch Pharmacol , vol.311 , pp. 263-272
    • Fowler, C.J.1    Oreland, L.2    Marcusson, J.3
  • 46
    • 0025988085 scopus 로고
    • MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease
    • Gerlach M., Riederer R., Przuntek R., et al. MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease. Eur J Pharmacol 208 (1991) 273-286
    • (1991) Eur J Pharmacol , vol.208 , pp. 273-286
    • Gerlach, M.1    Riederer, R.2    Przuntek, R.3
  • 47
    • 0004181515 scopus 로고    scopus 로고
    • Grundlagen, Klinik Therapie. Unter Mitarbeit von W. Götz und U. Sommer. Dritte, überarbeitete und erweiterte Auflage. XVII 368 Seiten
    • Gerlach M., Reichmann H., and Riederer P. "Die Parkinson-Krankheit" (2003), Grundlagen, Klinik Therapie. Unter Mitarbeit von W. Götz und U. Sommer. Dritte, überarbeitete und erweiterte Auflage. XVII 368 Seiten
    • (2003) "Die Parkinson-Krankheit"
    • Gerlach, M.1    Reichmann, H.2    Riederer, P.3
  • 48
    • 0023233231 scopus 로고
    • Inhibition of MAO-B, but not MAO-A, blocks DSP-4 toxicity on central NE neurons
    • Gibson C.J. Inhibition of MAO-B, but not MAO-A, blocks DSP-4 toxicity on central NE neurons. Eur J Pharmacol 141 (1987) 135-138
    • (1987) Eur J Pharmacol , vol.141 , pp. 135-138
    • Gibson, C.J.1
  • 49
    • 0007407081 scopus 로고
    • Neurotoxins and monoamine oxidase B inhibitors: possible mechanisms for the neuroprotective effect of (-)-deprenyl
    • Szelenyi I. (Ed), Birkhäuser, Basel
    • Glover V., and Sandler M. Neurotoxins and monoamine oxidase B inhibitors: possible mechanisms for the neuroprotective effect of (-)-deprenyl. In: Szelenyi I. (Ed). Inhibitors of Monoamine Oxidase B. Pharmacology and Clinical use in Neurodegenerative Disorders (1993), Birkhäuser, Basel 169-181
    • (1993) Inhibitors of Monoamine Oxidase B. Pharmacology and Clinical use in Neurodegenerative Disorders , pp. 169-181
    • Glover, V.1    Sandler, M.2
  • 50
    • 0036920181 scopus 로고    scopus 로고
    • Treatment intervention for Parkinson's disease: an evidence based assessment
    • Goetz C.G., Koller W.C., Poewe W., et al. Treatment intervention for Parkinson's disease: an evidence based assessment. Mov Disord 17 4 (2002) 38-39
    • (2002) Mov Disord , vol.17 , Issue.4 , pp. 38-39
    • Goetz, C.G.1    Koller, W.C.2    Poewe, W.3
  • 52
    • 0016829477 scopus 로고
    • Effects of monoamine oxidase inhibition by clorgyline, deprenil or tranylcypromine on 5-hydroxytryptamine concentrations in rat brain and hyperactivity following subsequent tryptophan administration
    • Green A.R., and Youdim M.B. Effects of monoamine oxidase inhibition by clorgyline, deprenil or tranylcypromine on 5-hydroxytryptamine concentrations in rat brain and hyperactivity following subsequent tryptophan administration. Br J Pharmacol 55 3 (1975) 415-422
    • (1975) Br J Pharmacol , vol.55 , Issue.3 , pp. 415-422
    • Green, A.R.1    Youdim, M.B.2
  • 53
    • 0017755902 scopus 로고
    • Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for the degree of inhibition of enzyme necessary for increased functional activity of dopamine and 5-hydroxytryptamine
    • Green A.R., Mitchell B.D., Tordoff A.F., et al. Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for the degree of inhibition of enzyme necessary for increased functional activity of dopamine and 5-hydroxytryptamine. Br J Pharmacol 60 3 (1977) 343-349
    • (1977) Br J Pharmacol , vol.60 , Issue.3 , pp. 343-349
    • Green, A.R.1    Mitchell, B.D.2    Tordoff, A.F.3
  • 54
  • 56
    • 0021285509 scopus 로고
    • Pharmacological modifications of the neurotoxic action of the noradrenaline neurotoxin DSP4 on central noradrenaline neurons
    • Hallman H., and Jonsson G. Pharmacological modifications of the neurotoxic action of the noradrenaline neurotoxin DSP4 on central noradrenaline neurons. Eur J Pharmacol 103 3-4 (1984) 269-278
    • (1984) Eur J Pharmacol , vol.103 , Issue.3-4 , pp. 269-278
    • Hallman, H.1    Jonsson, G.2
  • 57
    • 33644526575 scopus 로고    scopus 로고
    • Effects of co-administration of a selective serotonin reuptake inhibitor and monoamine oxidase inhibitors on 5-HT-related behavior in rats
    • Izumi T., Iwamoto N., Kitaichi Y., et al. Effects of co-administration of a selective serotonin reuptake inhibitor and monoamine oxidase inhibitors on 5-HT-related behavior in rats. Eur J Pharmacol 532 3 (2006) 258-264
    • (2006) Eur J Pharmacol , vol.532 , Issue.3 , pp. 258-264
    • Izumi, T.1    Iwamoto, N.2    Kitaichi, Y.3
  • 58
    • 0032610781 scopus 로고    scopus 로고
    • Combined and selective monoamine oxidase inhibition in the treatment of depression in Parkinson's disease
    • Jansen Steur E.N., and Ballering L.A. Combined and selective monoamine oxidase inhibition in the treatment of depression in Parkinson's disease. Adv Neurol 80 (1999) 505-509
    • (1999) Adv Neurol , vol.80 , pp. 505-509
    • Jansen Steur, E.N.1    Ballering, L.A.2
  • 59
    • 0014314486 scopus 로고
    • Some observations upon a new inhibitor of monoamine oxidase in brain tissue
    • Johnston J.P. Some observations upon a new inhibitor of monoamine oxidase in brain tissue. Biochem Pharmacol 17 (1968) 1285-1297
    • (1968) Biochem Pharmacol , vol.17 , pp. 1285-1297
    • Johnston, J.P.1
  • 60
    • 0019429465 scopus 로고
    • Selective acetylenic 'suicide' and reversible inhibitors of monoamine oxidase A and B
    • Kalir A., Sabbagh A., and Youdim M.B. Selective acetylenic 'suicide' and reversible inhibitors of monoamine oxidase A and B. Br J Pharmacol 73 (1981) 55-64
    • (1981) Br J Pharmacol , vol.73 , pp. 55-64
    • Kalir, A.1    Sabbagh, A.2    Youdim, M.B.3
  • 61
    • 0023502710 scopus 로고
    • R-(-)-deprenyl (Selegiline, Movergan) facilitates the activity of the nigrostriatal dopaminergic neuron
    • Knoll J. R-(-)-deprenyl (Selegiline, Movergan) facilitates the activity of the nigrostriatal dopaminergic neuron. J Neural Transm Suppl 25 (1987) 45-66
    • (1987) J Neural Transm Suppl , vol.25 , pp. 45-66
    • Knoll, J.1
  • 62
    • 0015274536 scopus 로고
    • Some puzzling pharmacological effects of monoamine oxidase inhibitors
    • Knoll J., and Magyar K. Some puzzling pharmacological effects of monoamine oxidase inhibitors. Adv Biochem Psychopharmacol 5 (1972) 393-408
    • (1972) Adv Biochem Psychopharmacol , vol.5 , pp. 393-408
    • Knoll, J.1    Magyar, K.2
  • 63
    • 0024843036 scopus 로고
    • Demonstration of monoamine oxidase-A and -B in the human brainstem by a histochemical technique
    • Konradi C., Kornhuber J., Froelich L., et al. Demonstration of monoamine oxidase-A and -B in the human brainstem by a histochemical technique. Neuroscience 33 2 (1989) 383-400
    • (1989) Neuroscience , vol.33 , Issue.2 , pp. 383-400
    • Konradi, C.1    Kornhuber, J.2    Froelich, L.3
  • 64
    • 0026532946 scopus 로고
    • Variations of monoamines and their metabolites in the human brain putamen
    • Konradi C., Kornhuber J., Sofic E., et al. Variations of monoamines and their metabolites in the human brain putamen. Brain Res 579 2 (1992) 285-290
    • (1992) Brain Res , vol.579 , Issue.2 , pp. 285-290
    • Konradi, C.1    Kornhuber, J.2    Sofic, E.3
  • 65
    • 0023728819 scopus 로고
    • Tyramine pressor effect in man: studies with moclobemide, a novel, reversible monoamine oxidase inhibitor
    • Korn A., Da Prada M., Raffesberg W., et al. Tyramine pressor effect in man: studies with moclobemide, a novel, reversible monoamine oxidase inhibitor. J Neural Transm Suppl 26 (1988) 57-71
    • (1988) J Neural Transm Suppl , vol.26 , pp. 57-71
    • Korn, A.1    Da Prada, M.2    Raffesberg, W.3
  • 66
    • 0030582079 scopus 로고    scopus 로고
    • Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylopyridinium
    • Koutsilieri E., Chen T.S., Rausch W.D., et al. Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylopyridinium. Eur J Pharmacol 306 (1996) 181-186
    • (1996) Eur J Pharmacol , vol.306 , pp. 181-186
    • Koutsilieri, E.1    Chen, T.S.2    Rausch, W.D.3
  • 67
    • 0032489392 scopus 로고    scopus 로고
    • Glyceraldehyde-3-phosphate dehydrogenase, the putative target of the antiapoptotic compounds CGP 3466 and R-(-)-deprenyl
    • Kragten E., Lalande I., Zimmermann K., et al. Glyceraldehyde-3-phosphate dehydrogenase, the putative target of the antiapoptotic compounds CGP 3466 and R-(-)-deprenyl. J Biol Chem 273 (1998) 5821-5828
    • (1998) J Biol Chem , vol.273 , pp. 5821-5828
    • Kragten, E.1    Lalande, I.2    Zimmermann, K.3
  • 68
    • 0029832455 scopus 로고    scopus 로고
    • Effect of long-term treatment with selective monoamine oxidase A and B inhibitors on dopamine release from rat striatum in vivo
    • Lamensdorf I., Youdim M.B., and Finberg J.P. Effect of long-term treatment with selective monoamine oxidase A and B inhibitors on dopamine release from rat striatum in vivo. J Neurochem 67 4 (1996) 1532-1539
    • (1996) J Neurochem , vol.67 , Issue.4 , pp. 1532-1539
    • Lamensdorf, I.1    Youdim, M.B.2    Finberg, J.P.3
  • 69
    • 0033385038 scopus 로고    scopus 로고
    • Does selegiline modify the progression of early Parkinson's disease? Results from a five-year study. The Norwegian-Danish Study Group
    • Larsen J.P., Boas J., and Erdal J.E. Does selegiline modify the progression of early Parkinson's disease? Results from a five-year study. The Norwegian-Danish Study Group. Eur J Neurol 6 (1999) 539-547
    • (1999) Eur J Neurol , vol.6 , pp. 539-547
    • Larsen, J.P.1    Boas, J.2    Erdal, J.E.3
  • 70
    • 8844287467 scopus 로고    scopus 로고
    • The neuropsychiatry of Parkinson's disease and related disorders
    • Lauterbach E.C. The neuropsychiatry of Parkinson's disease and related disorders. Psychiatr Clin North Am 27 4 (2004) 801-825
    • (2004) Psychiatr Clin North Am , vol.27 , Issue.4 , pp. 801-825
    • Lauterbach, E.C.1
  • 71
    • 0030891039 scopus 로고    scopus 로고
    • (-)-Deprenyl protection of 1-methyl-4-phenylpyridium ion (MPP+)-induced apoptosis independent of MAO-B inhibition
    • Le W., Jankovic J., Xie W., et al. (-)-Deprenyl protection of 1-methyl-4-phenylpyridium ion (MPP+)-induced apoptosis independent of MAO-B inhibition. Neurosci Lett 224 (1997) 197-200
    • (1997) Neurosci Lett , vol.224 , pp. 197-200
    • Le, W.1    Jankovic, J.2    Xie, W.3
  • 72
    • 0030865454 scopus 로고    scopus 로고
    • Slowing the progression of Alzheimer disease: methodologic issues
    • discussion S37-S39
    • Leber P. Slowing the progression of Alzheimer disease: methodologic issues. Alzheimer Dis Assoc Disord 11 Suppl 5 (1997) S10-S21; discussion S37-S39
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , Issue.SUPPL. 5
    • Leber, P.1
  • 73
    • 4344627571 scopus 로고    scopus 로고
    • Depression in Parkinson's disease: conceptual issues and clinical challenges
    • Leentjens A.F. Depression in Parkinson's disease: conceptual issues and clinical challenges. J Geriatr Psychiatry Neurol 17 3 (2004) 120-126
    • (2004) J Geriatr Psychiatry Neurol , vol.17 , Issue.3 , pp. 120-126
    • Leentjens, A.F.1
  • 74
    • 0017729733 scopus 로고
    • Deprenyl in Parkinson's disease
    • Lees A.J., Shaw K.M., Kohout L.L., et al. Deprenyl in Parkinson's disease. Lancet 2 8042 (1977) 791-795
    • (1977) Lancet , vol.2 , Issue.8042 , pp. 791-795
    • Lees, A.J.1    Shaw, K.M.2    Kohout, L.L.3
  • 76
    • 0028182738 scopus 로고
    • Behaviour of (-)-deprenyl and its analogues
    • Magyar K. Behaviour of (-)-deprenyl and its analogues. J Neural Transm Suppl 41 (1994) 167-175
    • (1994) J Neural Transm Suppl , vol.41 , pp. 167-175
    • Magyar, K.1
  • 77
    • 0031596692 scopus 로고    scopus 로고
    • The neuroprotective and neuronal rescue effects of (-)-deprenyl
    • Magyar K.B., Szende J., Lengyel J., et al. The neuroprotective and neuronal rescue effects of (-)-deprenyl. J Neural Transm 52 Suppl (1998) 109-123
    • (1998) J Neural Transm , vol.52 , Issue.SUPPL , pp. 109-123
    • Magyar, K.B.1    Szende, J.2    Lengyel, J.3
  • 78
    • 0028824983 scopus 로고
    • Delayed development of symptomatic improvement by (-)-deprenyl in Parkinson's disease
    • Mally J., Kovacs AB., and Stone TW. Delayed development of symptomatic improvement by (-)-deprenyl in Parkinson's disease. J. Neurol. Sci. 134 (1995) 143-145
    • (1995) J. Neurol. Sci. , vol.134 , pp. 143-145
    • Mally, J.1    Kovacs, AB.2    Stone, TW.3
  • 79
    • 0019185890 scopus 로고
    • L-deprenyl, a selective monoamine oxidase type-B inhibitor in endogenous depression
    • Mann J., and Gershon S. L-deprenyl, a selective monoamine oxidase type-B inhibitor in endogenous depression. Life Sci 26 (1980) 877-882
    • (1980) Life Sci , vol.26 , pp. 877-882
    • Mann, J.1    Gershon, S.2
  • 80
    • 0024585244 scopus 로고
    • A controlled study of antidepressant efficacy and side effects of (-)-deprenyl. A selective monoamine oxidase inhibitor
    • Mann J.J. A controlled study of antidepressant efficacy and side effects of (-)-deprenyl. A selective monoamine oxidase inhibitor. Arch Gen Psychiatry 46 (1989) 45-50
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 45-50
    • Mann, J.J.1
  • 81
    • 0001491507 scopus 로고    scopus 로고
    • Phase II evaluation of rasagiline mesylate (TVP-1012), a novel anti-parkinsonian drug, in parkinsonian patients not using levodopa/carbidopa
    • Marek K.L., Friedman J., Hauser R., et al. Phase II evaluation of rasagiline mesylate (TVP-1012), a novel anti-parkinsonian drug, in parkinsonian patients not using levodopa/carbidopa. Mov Disord 12 (1997) 838-846
    • (1997) Mov Disord , vol.12 , pp. 838-846
    • Marek, K.L.1    Friedman, J.2    Hauser, R.3
  • 82
    • 0034884148 scopus 로고    scopus 로고
    • Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol
    • Maruyama W., Akao Y., Youdim M.B., et al. Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol. J Neurochem 78 4 (2001) 727-735
    • (2001) J Neurochem , vol.78 , Issue.4 , pp. 727-735
    • Maruyama, W.1    Akao, Y.2    Youdim, M.B.3
  • 83
    • 0036719861 scopus 로고    scopus 로고
    • Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes
    • Maruyama W., Akao Y., Carrillo M.C., et al. Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes. Neurotoxicol Teratol 24 5 (2002) 675-682
    • (2002) Neurotoxicol Teratol , vol.24 , Issue.5 , pp. 675-682
    • Maruyama, W.1    Akao, Y.2    Carrillo, M.C.3
  • 84
    • 0345237921 scopus 로고    scopus 로고
    • Anti-apoptotic action of anti-Alzheimer drug, TV3326 [(N-propargyl)-(3R)-aminoindan-5-yl]-ethyl methyl carbamate, a novel cholinesterase-monoamine oxidase inhibitor
    • Maruyama W., Weinstock M., Youdim M.B., et al. Anti-apoptotic action of anti-Alzheimer drug, TV3326 [(N-propargyl)-(3R)-aminoindan-5-yl]-ethyl methyl carbamate, a novel cholinesterase-monoamine oxidase inhibitor. Neurosci Lett 341 3 (2003) 233-236
    • (2003) Neurosci Lett , vol.341 , Issue.3 , pp. 233-236
    • Maruyama, W.1    Weinstock, M.2    Youdim, M.B.3
  • 85
    • 0346848857 scopus 로고    scopus 로고
    • N-Propargyl-1(R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor
    • Maruyama W., Nitta A., Shamoto-Nagai M., et al. N-Propargyl-1(R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor. Neurochem Int 44 6 (2004) 393-400
    • (2004) Neurochem Int , vol.44 , Issue.6 , pp. 393-400
    • Maruyama, W.1    Nitta, A.2    Shamoto-Nagai, M.3
  • 86
    • 1842736312 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of safinamide, a neuroprotectant with antiparkinsonian and anticonvulsant activity
    • Marzo A., Dal Bo L., Monti N.C., et al. Pharmacokinetics and pharmacodynamics of safinamide, a neuroprotectant with antiparkinsonian and anticonvulsant activity. Pharmacol Res 50 1 (2004) 77-85
    • (2004) Pharmacol Res , vol.50 , Issue.1 , pp. 77-85
    • Marzo, A.1    Dal Bo, L.2    Monti, N.C.3
  • 87
    • 0018178409 scopus 로고
    • Anti-depressant potentiation of 5-hydroxytryptophan by L-deprenyl, an MAO "type B" inhibitor
    • Mendlewicz J., and Youdim M.B. Anti-depressant potentiation of 5-hydroxytryptophan by L-deprenyl, an MAO "type B" inhibitor. J Neural Transm 43 (1978) 279-286
    • (1978) J Neural Transm , vol.43 , pp. 279-286
    • Mendlewicz, J.1    Youdim, M.B.2
  • 88
    • 0018872281 scopus 로고
    • Anti-depressant potentiation of 5-hydroxytrytophan by l-deprenyl in affective disorder
    • Mendlewicz J., and Youdim M.B.H. Anti-depressant potentiation of 5-hydroxytrytophan by l-deprenyl in affective disorder. J Aff Disord 2 (1979) 137-146
    • (1979) J Aff Disord , vol.2 , pp. 137-146
    • Mendlewicz, J.1    Youdim, M.B.H.2
  • 89
    • 0020570351 scopus 로고
    • L-Deprenil, a selective monoamine oxidase type B inhibitor, in the treatment of depression: a double blind evaluation
    • Mendlewicz J., and Youdim M.B.H. L-Deprenil, a selective monoamine oxidase type B inhibitor, in the treatment of depression: a double blind evaluation. Br J Psychiatry 142 (1983) 508-511
    • (1983) Br J Psychiatry , vol.142 , pp. 508-511
    • Mendlewicz, J.1    Youdim, M.B.H.2
  • 90
    • 0037426229 scopus 로고    scopus 로고
    • Dementia with Lewy bodies-diagnosis and treatment
    • Mosimann U.P., and McKeith I.G. Dementia with Lewy bodies-diagnosis and treatment. Swiss Med Wkly 133 9-10 (2003) 131-142
    • (2003) Swiss Med Wkly , vol.133 , Issue.9-10 , pp. 131-142
    • Mosimann, U.P.1    McKeith, I.G.2
  • 91
    • 17744384689 scopus 로고    scopus 로고
    • Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease
    • Mössner R., Henneberg A., Schmitt A., et al. Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease. Mol Psychiatry 6 3 (2001) 350-352
    • (2001) Mol Psychiatry , vol.6 , Issue.3 , pp. 350-352
    • Mössner, R.1    Henneberg, A.2    Schmitt, A.3
  • 92
    • 0017052656 scopus 로고
    • Platelet and plasma amine oxidase activity in 680 normals: sex and age differences and stability over time
    • Murphy D.L., Wright C., Buchsbaum M., et al. Platelet and plasma amine oxidase activity in 680 normals: sex and age differences and stability over time. Biochem Med 16 (1976) 254-265
    • (1976) Biochem Med , vol.16 , pp. 254-265
    • Murphy, D.L.1    Wright, C.2    Buchsbaum, M.3
  • 93
    • 0031596707 scopus 로고    scopus 로고
    • Selegiline as immunostimulant-a novel mechanism of action?
    • Müller T., Kuhn W., Krüger R., et al. Selegiline as immunostimulant-a novel mechanism of action?. J Neural Transm Suppl 52 (1998) 321-328
    • (1998) J Neural Transm Suppl , vol.52 , pp. 321-328
    • Müller, T.1    Kuhn, W.2    Krüger, R.3
  • 95
    • 0031037786 scopus 로고    scopus 로고
    • L-(-)-desmethylselegiline, a metabolite of selegiline [L-(-)-deprenyl], protects mesencephalic dopamine neurons from excitotoxicity in vitro
    • Mytilineou C., Radcliffe P.M., and Olanow C.W. L-(-)-desmethylselegiline, a metabolite of selegiline [L-(-)-deprenyl], protects mesencephalic dopamine neurons from excitotoxicity in vitro. J Neurochem 68 (1997) 434-436
    • (1997) J Neurochem , vol.68 , pp. 434-436
    • Mytilineou, C.1    Radcliffe, P.M.2    Olanow, C.W.3
  • 96
    • 0031020650 scopus 로고    scopus 로고
    • L-deprenyl protects mesencephalic dopamine neurons from glutamate receptor-mediated toxicity in vitro
    • Mytilineou C., Radcliffe P., Leonardi E.K., et al. L-deprenyl protects mesencephalic dopamine neurons from glutamate receptor-mediated toxicity in vitro. J Neurochem 68 (1997) 33-39
    • (1997) J Neurochem , vol.68 , pp. 33-39
    • Mytilineou, C.1    Radcliffe, P.2    Leonardi, E.K.3
  • 97
    • 0038051500 scopus 로고    scopus 로고
    • Anti-apoptotic function of propargylamine inhibitors of type-B monoamine oxidase
    • Naoi M., Maruyama W., Youdim M.B., et al. Anti-apoptotic function of propargylamine inhibitors of type-B monoamine oxidase. Inflammopharmacology 11 2 (2003) 175-181
    • (2003) Inflammopharmacology , vol.11 , Issue.2 , pp. 175-181
    • Naoi, M.1    Maruyama, W.2    Youdim, M.B.3
  • 98
    • 33646794607 scopus 로고    scopus 로고
    • Systematic overview of drug interactions with antidepressant medications
    • Nieuwstraten C., Labiris N.R., and Holbrook A. Systematic overview of drug interactions with antidepressant medications. Can J Psychiatry 51 5 (2006) 300-316
    • (2006) Can J Psychiatry , vol.51 , Issue.5 , pp. 300-316
    • Nieuwstraten, C.1    Labiris, N.R.2    Holbrook, A.3
  • 99
    • 0020662487 scopus 로고
    • The deamination of dopamine by human brain monoamine oxidase
    • O'Carroll A.M., Fowler C.J., Phillips J.P., et al. The deamination of dopamine by human brain monoamine oxidase. Arch Pharmacol 322 (1983) 198-223
    • (1983) Arch Pharmacol , vol.322 , pp. 198-223
    • O'Carroll, A.M.1    Fowler, C.J.2    Phillips, J.P.3
  • 101
    • 0345019854 scopus 로고    scopus 로고
    • Selegiline delays the onset of disability in de novo parkinsonian patients. Swedish Parkinson Study Group
    • Palhagen S., Heinonen E.H., and Hagglund J. Selegiline delays the onset of disability in de novo parkinsonian patients. Swedish Parkinson Study Group. J Neurol 51 (1998) 520-525
    • (1998) J Neurol , vol.51 , pp. 520-525
    • Palhagen, S.1    Heinonen, E.H.2    Hagglund, J.3
  • 102
    • 0024456653 scopus 로고
    • Effect of deprenyl on the progression of disability in early Parkinson's disease. The Parkinson Study Group
    • Parkinson Study Group
    • Parkinson Study Group. Effect of deprenyl on the progression of disability in early Parkinson's disease. The Parkinson Study Group. N. Engl. J. Med. 321 (1989) 1364-1371
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1364-1371
  • 103
    • 0027509754 scopus 로고
    • A controlled trial of lazabemide (RO19-6327) in untreated Parkinson's disease
    • Parkinson Study Group
    • Parkinson Study Group. A controlled trial of lazabemide (RO19-6327) in untreated Parkinson's disease. Ann. Neurol. 33 (1993) 350-356
    • (1993) Ann. Neurol. , vol.33 , pp. 350-356
  • 104
    • 0027530638 scopus 로고
    • Effects of Tocopherol and Deprenyl on the Progression of Disability in Early Parkinson's Disease
    • Parkinson Study Group
    • Parkinson Study Group. Effects of Tocopherol and Deprenyl on the Progression of Disability in Early Parkinson's Disease. New Engl. J. Med. 328 (1993) 176-183
    • (1993) New Engl. J. Med. , vol.328 , pp. 176-183
  • 105
    • 0036894795 scopus 로고    scopus 로고
    • A controlled trial of rasagiline in early Parkinson disease: the TEMPO Study
    • Parkinson Study Group
    • Parkinson Study Group. A controlled trial of rasagiline in early Parkinson disease: the TEMPO Study. Arch Neurol 59 12 (2002) 1937-1943
    • (2002) Arch Neurol , vol.59 , Issue.12 , pp. 1937-1943
  • 106
    • 2342655732 scopus 로고    scopus 로고
    • A controlled, randomized, delayed-start study of rasagiline in early Parkinson disease
    • Parkinson Study Group
    • Parkinson Study Group. A controlled, randomized, delayed-start study of rasagiline in early Parkinson disease. Arch Neurol 61 4 (2004) 561-566
    • (2004) Arch Neurol , vol.61 , Issue.4 , pp. 561-566
  • 107
    • 13444302612 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson disease and motor fluctuations: the PRESTO study
    • Parkinson Study Group
    • Parkinson Study Group. A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson disease and motor fluctuations: the PRESTO study. Arch Neurol 62 2 (2005) 241-248
    • (2005) Arch Neurol , vol.62 , Issue.2 , pp. 241-248
  • 108
    • 77956767839 scopus 로고    scopus 로고
    • Antiapoptotic actions of monoamine oxidase B inhibitors
    • Paterson I.A., and Tatton W.G. Antiapoptotic actions of monoamine oxidase B inhibitors. Adv Pharmacol 42 (1998) 312-315
    • (1998) Adv Pharmacol , vol.42 , pp. 312-315
    • Paterson, I.A.1    Tatton, W.G.2
  • 109
    • 0025026669 scopus 로고
    • Phenylethylamine in the CNS: effects of monoamine oxidase inhibiting drugs, deuterium substitution and lesions and its role in the neuromodulation of catecholaminergic neurotransmission
    • Paterson I.A., Boulton A.A., and Juorio A.V. Phenylethylamine in the CNS: effects of monoamine oxidase inhibiting drugs, deuterium substitution and lesions and its role in the neuromodulation of catecholaminergic neurotransmission. J Neural Transm Suppl 29 (1990) 119-129
    • (1990) J Neural Transm Suppl , vol.29 , pp. 119-129
    • Paterson, I.A.1    Boulton, A.A.2    Juorio, A.V.3
  • 110
    • 0031914155 scopus 로고    scopus 로고
    • R-deprenyl and R-2-heptyl-N-methylpropargylamine prevent apoptosis in cerebellar granule neurons induced by cytosine arabinoside but not low extracellular potassium
    • Paterson I.A., Zhang D., Warrington R.C., et al. R-deprenyl and R-2-heptyl-N-methylpropargylamine prevent apoptosis in cerebellar granule neurons induced by cytosine arabinoside but not low extracellular potassium. J Neurochem 70 (1998) 515-523
    • (1998) J Neurochem , vol.70 , pp. 515-523
    • Paterson, I.A.1    Zhang, D.2    Warrington, R.C.3
  • 111
    • 67649481394 scopus 로고
    • Monoamine oxidase inhibitors: new developments
    • Paykel E., and Youdim M.B.H. Monoamine oxidase inhibitors: new developments. Clin Neuropharmacol 16 Suppl 2 (1993) 96-212
    • (1993) Clin Neuropharmacol , vol.16 , Issue.SUPPL. 2 , pp. 96-212
    • Paykel, E.1    Youdim, M.B.H.2
  • 112
    • 0026502707 scopus 로고
    • Moclobemide: a range of opportunities
    • Priest R.G. Moclobemide: a range of opportunities. Psychopharmacology (Berl) 106 (1992) S140-S141
    • (1992) Psychopharmacology (Berl) , vol.106
    • Priest, R.G.1
  • 113
    • 0023475584 scopus 로고
    • The effect of R-(-)-deprenyl in de novo Parkinson patients on combination therapy with levodopa and decarboxylase inhibitor
    • Przuntek H., and Kuhn W. The effect of R-(-)-deprenyl in de novo Parkinson patients on combination therapy with levodopa and decarboxylase inhibitor. J. Neural Transm 25 (1987) 97-104
    • (1987) J. Neural Transm , vol.25 , pp. 97-104
    • Przuntek, H.1    Kuhn, W.2
  • 114
    • 0033038628 scopus 로고    scopus 로고
    • SELEDO: a 5-year long-term trial on the effect of selegiline in early Parkinsonian patients treated with levodopa
    • Przuntek H., Conrad B., and Dichgans J. SELEDO: a 5-year long-term trial on the effect of selegiline in early Parkinsonian patients treated with levodopa. J. Neurol. 6 (1999) 141-150
    • (1999) J. Neurol. , vol.6 , pp. 141-150
    • Przuntek, H.1    Conrad, B.2    Dichgans, J.3
  • 115
    • 15844386001 scopus 로고    scopus 로고
    • LARGO Study Group. Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial
    • Rascol O., Brooks D.J., Melamed E., et al. LARGO Study Group. Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial. Lancet 365 9463 (2005) 947-954
    • (2005) Lancet , vol.365 , Issue.9463 , pp. 947-954
    • Rascol, O.1    Brooks, D.J.2    Melamed, E.3
  • 116
    • 0031913673 scopus 로고    scopus 로고
    • (-)-Deprenyl attenuates spinal motor neuron degeneration and associated locomotor deficits in rats subjected to spinal cord ischemia
    • Ravikumar R., Lakshmana M.K., Rao B.S., et al. (-)-Deprenyl attenuates spinal motor neuron degeneration and associated locomotor deficits in rats subjected to spinal cord ischemia. Exp Neurol 149 (1998) 123-129
    • (1998) Exp Neurol , vol.149 , pp. 123-129
    • Ravikumar, R.1    Lakshmana, M.K.2    Rao, B.S.3
  • 117
    • 0031260363 scopus 로고    scopus 로고
    • Deprenyl induces GFAP immunoreactivity in the intact and injured dopaminergic nigrostriatal system but fails to counteract axotomy-induced degenerative changes
    • Revuelta M., Venero J.L., Machado A., et al. Deprenyl induces GFAP immunoreactivity in the intact and injured dopaminergic nigrostriatal system but fails to counteract axotomy-induced degenerative changes. Glia 21 (1997) 204-216
    • (1997) Glia , vol.21 , pp. 204-216
    • Revuelta, M.1    Venero, J.L.2    Machado, A.3
  • 118
    • 0345490838 scopus 로고    scopus 로고
    • Selegiline's neuroprotective capacity revisited
    • Riederer P., and Lachenmayer L. Selegiline's neuroprotective capacity revisited. J Neural Transm 110 11 (2003) 1273-1278
    • (2003) J Neural Transm , vol.110 , Issue.11 , pp. 1273-1278
    • Riederer, P.1    Lachenmayer, L.2
  • 119
    • 5144219530 scopus 로고
    • Human brain monoamine oxidase activity and monoaminemetabolism in Parkinsonian patients treated with L-deprenyl
    • Riederer P., and Youdim M.B.H. Human brain monoamine oxidase activity and monoaminemetabolism in Parkinsonian patients treated with L-deprenyl. J Neurochem 45 (1986) 1349-1356
    • (1986) J Neurochem , vol.45 , pp. 1349-1356
    • Riederer, P.1    Youdim, M.B.H.2
  • 120
    • 0023174117 scopus 로고
    • Location of MAO-A and MAO-B in human brain, a step in understanding the therapeutic action of L-deprenyl
    • Riederer P., Konradi C., Schay V., et al. Location of MAO-A and MAO-B in human brain, a step in understanding the therapeutic action of L-deprenyl. Adv Neurol 45 (1986) 111-119
    • (1986) Adv Neurol , vol.45 , pp. 111-119
    • Riederer, P.1    Konradi, C.2    Schay, V.3
  • 121
    • 3242772321 scopus 로고    scopus 로고
    • Clinical applications of MAO-inhibitors
    • Riederer P., Lachenmayer L., and Laux G. Clinical applications of MAO-inhibitors. Curr Med Chem 11 (2004) 2033-2043
    • (2004) Curr Med Chem , vol.11 , pp. 2033-2043
    • Riederer, P.1    Lachenmayer, L.2    Laux, G.3
  • 123
    • 0027292598 scopus 로고
    • Deprenyl increases survival of rat foetal nigral neurones in culture
    • Roy E., and Bédard P.J. Deprenyl increases survival of rat foetal nigral neurones in culture. Neuroreport 4 (1993) 1183-1186
    • (1993) Neuroreport , vol.4 , pp. 1183-1186
    • Roy, E.1    Bédard, P.J.2
  • 124
    • 0038155162 scopus 로고    scopus 로고
    • Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor
    • Sagi Y., Weinstock M., and Youdim M.B. Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor. J Neurochem 86 2 (2003) 290-297
    • (2003) J Neurochem , vol.86 , Issue.2 , pp. 290-297
    • Sagi, Y.1    Weinstock, M.2    Youdim, M.B.3
  • 125
    • 33751078859 scopus 로고    scopus 로고
    • Activation of tyrosine kinase receptor signaling pathway by rasagiline facilitates neurorescue and restoration of nigrostriatal dopamine neurons in post-MPTP-induced parkinsonism
    • Sagi Y., Mandel S., Amit L., et al. Activation of tyrosine kinase receptor signaling pathway by rasagiline facilitates neurorescue and restoration of nigrostriatal dopamine neurons in post-MPTP-induced parkinsonism. Neurobiol Dis 25 1 (2006) 35-44
    • (2006) Neurobiol Dis , vol.25 , Issue.1 , pp. 35-44
    • Sagi, Y.1    Mandel, S.2    Amit, L.3
  • 126
    • 0026514670 scopus 로고
    • Deprenyl reduces the death of motoneurons caused by axotomy
    • Salo P.T., and Tatton W.G. Deprenyl reduces the death of motoneurons caused by axotomy. J Neurosci Res 31 (1992) 394-400
    • (1992) J Neurosci Res , vol.31 , pp. 394-400
    • Salo, P.T.1    Tatton, W.G.2
  • 128
    • 0030668746 scopus 로고    scopus 로고
    • +) neurotoxicity by deprenyl in organotypic canine substantia nigra cultures
    • +) neurotoxicity by deprenyl in organotypic canine substantia nigra cultures. J Neural Transm 104 (1997) 875-885
    • (1997) J Neural Transm , vol.104 , pp. 875-885
    • Schmidt, D.E.1    Ebert, M.H.2    Lynn, J.C.3
  • 129
    • 0030574241 scopus 로고    scopus 로고
    • Selegiline enhances NGF synthesis and protects central nervous system (CNS) neurons from excitotoxic and ischemic damage
    • Semokova I., Wolz P., Schilling M., et al. Selegiline enhances NGF synthesis and protects central nervous system (CNS) neurons from excitotoxic and ischemic damage. Eur J Pharmacol 315 (1996) 19-30
    • (1996) Eur J Pharmacol , vol.315 , pp. 19-30
    • Semokova, I.1    Wolz, P.2    Schilling, M.3
  • 130
    • 0028121120 scopus 로고
    • Increased CNTF gene expression in process-bearing astrocytes following injury is augmented by R(-)-deprenyl
    • Seniuk N.A., Henderson J.T., Tatton W.G., et al. Increased CNTF gene expression in process-bearing astrocytes following injury is augmented by R(-)-deprenyl. J Neurosci Res 37 (1994) 278-286
    • (1994) J Neurosci Res , vol.37 , pp. 278-286
    • Seniuk, N.A.1    Henderson, J.T.2    Tatton, W.G.3
  • 131
    • 0036231440 scopus 로고    scopus 로고
    • Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial
    • Shoulson I., Oakes D., and Fahn S. Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial. J. Ann. Neurol. 51 (2002) 604-612
    • (2002) J. Ann. Neurol. , vol.51 , pp. 604-612
    • Shoulson, I.1    Oakes, D.2    Fahn, S.3
  • 132
    • 0029100464 scopus 로고
    • The therapeutic potential of moclobemide, a reversible selective monoamine oxidase A inhibitor in Parkinson's disease
    • Sieradzan K., Chanon S., Stern G., et al. The therapeutic potential of moclobemide, a reversible selective monoamine oxidase A inhibitor in Parkinson's disease. Clin Psychopharmacol 15 (1995) 51S-60S
    • (1995) Clin Psychopharmacol , vol.15
    • Sieradzan, K.1    Chanon, S.2    Stern, G.3
  • 133
    • 0025963728 scopus 로고
    • The interaction of monoamine oxidases with tertiary amines
    • Singer T.P., and Ramsay R.R. The interaction of monoamine oxidases with tertiary amines. Biochem Soc Trans 19 (1991) 211-215
    • (1991) Biochem Soc Trans , vol.19 , pp. 211-215
    • Singer, T.P.1    Ramsay, R.R.2
  • 134
    • 84996059578 scopus 로고
    • Selegiline and levodopa in early of moderately advanced Parkinson's disease: a double-blind controlled short- and longterm study
    • Sivertsen B., Dupont E., and Mikkelsen B. Selegiline and levodopa in early of moderately advanced Parkinson's disease: a double-blind controlled short- and longterm study. E. Acta Neurol. Scand. 126 (1989) 147-152
    • (1989) E. Acta Neurol. Scand. , vol.126 , pp. 147-152
    • Sivertsen, B.1    Dupont, E.2    Mikkelsen, B.3
  • 135
    • 0032101092 scopus 로고    scopus 로고
    • Sparing by rasagiline (TVP-1012) of cholinergic functions and behavior in the postnatal anoxia rat
    • Speiser Z., Katzir O., Rehavi M., et al. Sparing by rasagiline (TVP-1012) of cholinergic functions and behavior in the postnatal anoxia rat. Pharmacol Biochem Behav 60 (1998) 387-393
    • (1998) Pharmacol Biochem Behav , vol.60 , pp. 387-393
    • Speiser, Z.1    Katzir, O.2    Rehavi, M.3
  • 136
    • 0031596710 scopus 로고    scopus 로고
    • Effects of N-propargyl-1-(R)aminoindan (rasagiline) in models of motor and cognition disorders
    • Speiser Z., Levy R., and Cohen S. Effects of N-propargyl-1-(R)aminoindan (rasagiline) in models of motor and cognition disorders. J Neural Transm Suppl 52 (1998) 287-300
    • (1998) J Neural Transm Suppl , vol.52 , pp. 287-300
    • Speiser, Z.1    Levy, R.2    Cohen, S.3
  • 137
    • 0028949807 scopus 로고
    • Inhibition of MAO-B protects against MDMA-induced neurotoxicity in the striatum
    • Sprague J.E., and Nichols D.E. Inhibition of MAO-B protects against MDMA-induced neurotoxicity in the striatum. Psychopharmacology (Berl) 118 (1995) 357-364
    • (1995) Psychopharmacology (Berl) , vol.118 , pp. 357-364
    • Sprague, J.E.1    Nichols, D.E.2
  • 138
    • 0031901240 scopus 로고    scopus 로고
    • The therapeutic effect of moclobemide, a reversible selective monoamine oxidase A inhibitor, in Parkinson's disease
    • Sternic N., Kacar A., Filipovic S., et al. The therapeutic effect of moclobemide, a reversible selective monoamine oxidase A inhibitor, in Parkinson's disease. Clin Neuropharmacol 21 (1998) 93-96
    • (1998) Clin Neuropharmacol , vol.21 , pp. 93-96
    • Sternic, N.1    Kacar, A.2    Filipovic, S.3
  • 139
    • 0037153195 scopus 로고    scopus 로고
    • Novel dual inhibitors of AChE and MAO derived from hydroxyl aminoindan and phenetylamine as potential treatment for Alzheimer's disease
    • Sterling J., Tamas T., Toth G., et al. Novel dual inhibitors of AChE and MAO derived from hydroxyl aminoindan and phenetylamine as potential treatment for Alzheimer's disease. J Med Chem 45 24 (2002) 5260-5279
    • (2002) J Med Chem , vol.45 , Issue.24 , pp. 5260-5279
    • Sterling, J.1    Tamas, T.2    Toth, G.3
  • 140
    • 4143093673 scopus 로고    scopus 로고
    • Safinamide Parkinson's Study Group. Improvement of motor function in early Parkinson disease by safinamide
    • Stocchi F., Arnold G., Onofrj M., et al. Safinamide Parkinson's Study Group. Improvement of motor function in early Parkinson disease by safinamide. Neurology 63 4 (2004) 746-748
    • (2004) Neurology , vol.63 , Issue.4 , pp. 746-748
    • Stocchi, F.1    Arnold, G.2    Onofrj, M.3
  • 142
    • 0029731378 scopus 로고    scopus 로고
    • Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration
    • Tatton W.G., and Chalmers-Redman R.M. Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration. Neurology 47 Suppl 3 (1996) S171-S183
    • (1996) Neurology , vol.47 , Issue.SUPPL. 3
    • Tatton, W.G.1    Chalmers-Redman, R.M.2
  • 143
    • 0027941312 scopus 로고
    • (-)-Deprenyl reduces PC12 apoptosis by inducing new protein synthesis
    • Tatton W.G., Ju W.Y., Holland D.P., et al. (-)-Deprenyl reduces PC12 apoptosis by inducing new protein synthesis. J Neurochem 63 (1994) 1572-1575
    • (1994) J Neurochem , vol.63 , pp. 1572-1575
    • Tatton, W.G.1    Ju, W.Y.2    Holland, D.P.3
  • 144
    • 0030300164 scopus 로고    scopus 로고
    • (-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase
    • Tatton W.G., Wadia J.S., Ju W.Y., et al. (-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase. J Neural Transm 48 (1996) 45-59
    • (1996) J Neural Transm , vol.48 , pp. 45-59
    • Tatton, W.G.1    Wadia, J.S.2    Ju, W.Y.3
  • 145
    • 0024343466 scopus 로고
    • The effect of deprenyl (selegiline) on the natural history of Parkinson's disease
    • Tetrud J.W., and Langston JW. The effect of deprenyl (selegiline) on the natural history of Parkinson's disease. J. W. Science 245 (1990) 519-522
    • (1990) J. W. Science , vol.245 , pp. 519-522
    • Tetrud, J.W.1    Langston, JW.2
  • 146
    • 0031050979 scopus 로고    scopus 로고
    • L-deprenyl and MDL72974 do not improve the recovery of dopaminergic cells following systemic administration of MPTP in mouse
    • Thiffault C., Lamarre-Theroux L., Quirion R., et al. L-deprenyl and MDL72974 do not improve the recovery of dopaminergic cells following systemic administration of MPTP in mouse. Mol Brain Res 44 (1997) 238-244
    • (1997) Mol Brain Res , vol.44 , pp. 238-244
    • Thiffault, C.1    Lamarre-Theroux, L.2    Quirion, R.3
  • 147
    • 0030601953 scopus 로고    scopus 로고
    • L-deprenyl fails to protect mesencephalic dopamine neurons and PC12 cells from the neurotoxic effects of 1-methyl-4-phenylpyridinium ion
    • Vaglini F., Pardini C., Cavalletti M., et al. L-deprenyl fails to protect mesencephalic dopamine neurons and PC12 cells from the neurotoxic effects of 1-methyl-4-phenylpyridinium ion. Brain Res 741 (1996) 68-74
    • (1996) Brain Res , vol.741 , pp. 68-74
    • Vaglini, F.1    Pardini, C.2    Cavalletti, M.3
  • 148
    • 0031890109 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: time course and modification by (-)-deprenyl
    • Wadia J.S., Chalmers-Redman R.M., Ju W.J., et al. Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: time course and modification by (-)-deprenyl. J Neurosci 18 (1998) 932-947
    • (1998) J Neurosci , vol.18 , pp. 932-947
    • Wadia, J.S.1    Chalmers-Redman, R.M.2    Ju, W.J.3
  • 149
    • 2342426425 scopus 로고    scopus 로고
    • Zydis Selegiline Study Group. Zydis selegiline reduces off time in Parkinson's disease patients with motor fluctuations: a 3-month, randomized, placebo-controlled study
    • Waters C.H., Sethi K.D., Hauser R.A., et al. Zydis Selegiline Study Group. Zydis selegiline reduces off time in Parkinson's disease patients with motor fluctuations: a 3-month, randomized, placebo-controlled study. Mov Disord 19 (2004) 426-432
    • (2004) Mov Disord , vol.19 , pp. 426-432
    • Waters, C.H.1    Sethi, K.D.2    Hauser, R.A.3
  • 150
    • 6944242126 scopus 로고    scopus 로고
    • Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members
    • Weinreb O., Bar-Am O., Amit T., et al. Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members. FASEB J 18 12 (2004) 1471-1473
    • (2004) FASEB J , vol.18 , Issue.12 , pp. 1471-1473
    • Weinreb, O.1    Bar-Am, O.2    Amit, T.3
  • 151
    • 0034525115 scopus 로고    scopus 로고
    • TV 3326, a novel neuroprotective drug with cholinesterase and monoamine oxidase inhibitory activities for the treatment of Alzheimer's disease
    • Weinstock M., Bejar C., Wang R.H., et al. TV 3326, a novel neuroprotective drug with cholinesterase and monoamine oxidase inhibitory activities for the treatment of Alzheimer's disease. J Neural Transm Suppl 60 (2000) 157-169
    • (2000) J Neural Transm Suppl , vol.60 , pp. 157-169
    • Weinstock, M.1    Bejar, C.2    Wang, R.H.3
  • 152
    • 0034932067 scopus 로고    scopus 로고
    • Neuroprotective effects of novel cholinesterase inhibitors derived from rasagiline as potential anti-Alzheimer drugs
    • Weinstock M., Kirschbaum-Slager N., Lazarovici P., et al. Neuroprotective effects of novel cholinesterase inhibitors derived from rasagiline as potential anti-Alzheimer drugs. Ann NY Acad Sci 939 (2001) 148-161
    • (2001) Ann NY Acad Sci , vol.939 , pp. 148-161
    • Weinstock, M.1    Kirschbaum-Slager, N.2    Lazarovici, P.3
  • 153
    • 0036121418 scopus 로고    scopus 로고
    • Effect of TV 3326, a novel monoamine-oxidase cholinesterase inhibitor, in rat models of anxiety and depression
    • Weinstock M., Poltyrev T., Bejar C., et al. Effect of TV 3326, a novel monoamine-oxidase cholinesterase inhibitor, in rat models of anxiety and depression. Psychopharmacology (Berl) 160 3 (2002) 318-324
    • (2002) Psychopharmacology (Berl) , vol.160 , Issue.3 , pp. 318-324
    • Weinstock, M.1    Poltyrev, T.2    Bejar, C.3
  • 154
    • 0036849156 scopus 로고    scopus 로고
    • Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits
    • Weinstock M., Gorodetsky E., Wang R.H., et al. Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits. Neuropharmacology 43 6 (2002) 999-1005
    • (2002) Neuropharmacology , vol.43 , Issue.6 , pp. 999-1005
    • Weinstock, M.1    Gorodetsky, E.2    Wang, R.H.3
  • 155
    • 0038012567 scopus 로고    scopus 로고
    • A novel cholinesterase and brain-selective monoamine oxidase inhibitor for the treatment of dementia comorbid with depression and Parkinson's disease
    • Weinstock M., Gorodetsky E., Poltyrev T., et al. A novel cholinesterase and brain-selective monoamine oxidase inhibitor for the treatment of dementia comorbid with depression and Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry 27 4 (2003) 555-561
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , Issue.4 , pp. 555-561
    • Weinstock, M.1    Gorodetsky, E.2    Poltyrev, T.3
  • 156
    • 0141501334 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for dementia with Lewy bodies
    • CD003672
    • Wild R., Pettit T., and Burns A. Cholinesterase inhibitors for dementia with Lewy bodies. Cochrane Database Syst Rev 3 (2003) CD003672
    • (2003) Cochrane Database Syst Rev , vol.3
    • Wild, R.1    Pettit, T.2    Burns, A.3
  • 157
    • 0030452808 scopus 로고    scopus 로고
    • Selegiline stimulates biosynthesis of cytokines interleukin-1 beta and interleukin-6
    • Wilfried K., Müller T., Kruger R., et al. Selegiline stimulates biosynthesis of cytokines interleukin-1 beta and interleukin-6. Neuroreport 7 (1997) 2847-2848
    • (1997) Neuroreport , vol.7 , pp. 2847-2848
    • Wilfried, K.1    Müller, T.2    Kruger, R.3
  • 158
    • 0026057114 scopus 로고
    • Modulation of the NMDA receptor by polyamines
    • Williams K., Romano C., Dichter M.A., et al. Modulation of the NMDA receptor by polyamines. Life Sci 48 (1991) 469-498
    • (1991) Life Sci , vol.48 , pp. 469-498
    • Williams, K.1    Romano, C.2    Dichter, M.A.3
  • 160
    • 0029779755 scopus 로고    scopus 로고
    • Suppression of hydroxyl radical formation and protection of nigral neurons by l-deprenyl (selegiline)
    • Wu R.M., and Murphy DL and Chiueh C.C. Suppression of hydroxyl radical formation and protection of nigral neurons by l-deprenyl (selegiline). Ann NY Acad Sci 786 (1996) 379-390
    • (1996) Ann NY Acad Sci , vol.786 , pp. 379-390
    • Wu, R.M.1    Murphy DL and Chiueh, C.C.2
  • 161
    • 0642303109 scopus 로고    scopus 로고
    • The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing
    • Yogev-Falach M., Amit T., Bar-Am O., et al. The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing. FASEB J 17 15 (2003) 2325-2327
    • (2003) FASEB J , vol.17 , Issue.15 , pp. 2325-2327
    • Yogev-Falach, M.1    Amit, T.2    Bar-Am, O.3
  • 162
    • 5144234171 scopus 로고
    • Reversible and Selective Inhibitors of Monoamine Oxidase: New Findings
    • Youdim M.B.H. Reversible and Selective Inhibitors of Monoamine Oxidase: New Findings. Acta Psyuchiat, Scand 91 (1995) 1-43
    • (1995) Acta Psyuchiat, Scand , vol.91 , pp. 1-43
    • Youdim, M.B.H.1
  • 163
    • 11144245220 scopus 로고    scopus 로고
    • Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders
    • Youdim M.B., and Buccafusco J.J. Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders. Trends Pharmacol Sci 26 1 (2005) 27-35
    • (2005) Trends Pharmacol Sci , vol.26 , Issue.1 , pp. 27-35
    • Youdim, M.B.1    Buccafusco, J.J.2
  • 164
    • 17644375125 scopus 로고    scopus 로고
    • CNS Targets for multi-functional drugs in the treatment of Alzheimer's and Parkinson's diseases
    • Youdim M.B., and Buccafusco J.J. CNS Targets for multi-functional drugs in the treatment of Alzheimer's and Parkinson's diseases. J Neural Transm 111 (2005) 519-537
    • (2005) J Neural Transm , vol.111 , pp. 519-537
    • Youdim, M.B.1    Buccafusco, J.J.2
  • 165
    • 0027264145 scopus 로고
    • Dopamine metabolism and neurotransmission in primate brain in relationship to monoamine oxidase A and B inhibition
    • Youdim M.B., and Riederer P. Dopamine metabolism and neurotransmission in primate brain in relationship to monoamine oxidase A and B inhibition. J Neural Transm 91 (1993) 181-195
    • (1993) J Neural Transm , vol.91 , pp. 181-195
    • Youdim, M.B.1    Riederer, P.2
  • 166
    • 0027496797 scopus 로고
    • The relevance of glial monoamine oxidase-B and polyamines to the action of selegiline in Parkinson's disease
    • Youdim M.B., and Riederer P. The relevance of glial monoamine oxidase-B and polyamines to the action of selegiline in Parkinson's disease. Mov Disord 8 Suppl 1 (1993) S8-S13
    • (1993) Mov Disord , vol.8 , Issue.SUPPL. 1
    • Youdim, M.B.1    Riederer, P.2
  • 167
    • 0035568344 scopus 로고    scopus 로고
    • Molecular basis of neuroprotective activities of rasagaline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate.]
    • Youdim M.B., and Weinstock M. Molecular basis of neuroprotective activities of rasagaline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate.]. Cell Mol Neurobiol 21 6 (2001) 555-573
    • (2001) Cell Mol Neurobiol , vol.21 , Issue.6 , pp. 555-573
    • Youdim, M.B.1    Weinstock, M.2
  • 168
    • 5144224957 scopus 로고
    • The effect of heat, pH and riboflavin deficiency on monoamine oxidase activity
    • Youdim M.B.H., and Sourkes T.L. The effect of heat, pH and riboflavin deficiency on monoamine oxidase activity. Can J Biochem 43 (1965) 1305-1318
    • (1965) Can J Biochem , vol.43 , pp. 1305-1318
    • Youdim, M.B.H.1    Sourkes, T.L.2
  • 169
    • 0015530606 scopus 로고
    • Human brain monoamine oxidase, multiple forms and selective inhibitors
    • Youdim M.B., Collins G.G., Sandler M., et al. Human brain monoamine oxidase, multiple forms and selective inhibitors. Nature 236 (1972) 225-228
    • (1972) Nature , vol.236 , pp. 225-228
    • Youdim, M.B.1    Collins, G.G.2    Sandler, M.3
  • 170
    • 85058497607 scopus 로고
    • The role of 5-hydroxytryptamine, dopamine and MAO in the production of hyperactivity
    • Birkmayer W., and Hornykiewicz O. (Eds), Editiones Roche, Base
    • Youdim M.B.H., Green A.R., and Grahame-Smith D.G. The role of 5-hydroxytryptamine, dopamine and MAO in the production of hyperactivity. In: Birkmayer W., and Hornykiewicz O. (Eds). Advances in Parkinsonism (1976), Editiones Roche, Base l155-l163
    • (1976) Advances in Parkinsonism
    • Youdim, M.B.H.1    Green, A.R.2    Grahame-Smith, D.G.3
  • 171
    • 0000083255 scopus 로고
    • Monoamine oxidase
    • Trendelengurg U., and Weiner U. (Eds), Springer-Verlag, Berlin
    • Youdim M.B.H., Finberg J.P.M., and Tipton K.F. Monoamine oxidase. In: Trendelengurg U., and Weiner U. (Eds). Catecholamine II (1988), Springer-Verlag, Berlin 119-192
    • (1988) Catecholamine II , pp. 119-192
    • Youdim, M.B.H.1    Finberg, J.P.M.2    Tipton, K.F.3
  • 172
    • 0023711569 scopus 로고
    • The cheese effect and new reversible MAO-A inhibitors
    • Youdim M.B.H., Da Prada M., and Amrein R. The cheese effect and new reversible MAO-A inhibitors. J Neural Transm Suppl 26 (1988)
    • (1988) J Neural Transm , Issue.SUPPL. 26
    • Youdim, M.B.H.1    Da Prada, M.2    Amrein, R.3
  • 173
    • 0035130289 scopus 로고    scopus 로고
    • Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B
    • Youdim M.B., Gross A., and Finberg J.P. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol 132 2 (2001) 500-506
    • (2001) Br J Pharmacol , vol.132 , Issue.2 , pp. 500-506
    • Youdim, M.B.1    Gross, A.2    Finberg, J.P.3
  • 174
    • 0034941767 scopus 로고    scopus 로고
    • The anti-Parkinson drug rasagiline and its cholinesterase inhibitor derivatives exert neuroprotection unrelated to MAO inhibition cell culture and in vivo
    • Youdim M.B., Wadia A., Tatton W., et al. The anti-Parkinson drug rasagiline and its cholinesterase inhibitor derivatives exert neuroprotection unrelated to MAO inhibition cell culture and in vivo. Ann NY Acad Sci 939 (2001) 450-458
    • (2001) Ann NY Acad Sci , vol.939 , pp. 450-458
    • Youdim, M.B.1    Wadia, A.2    Tatton, W.3
  • 175
    • 0642345197 scopus 로고    scopus 로고
    • The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagiline
    • Youdim M.B., Amit T., and Falach-Yogev M. The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagiline. Biochem Pharmacol 66 8 (2003) 1635-1641
    • (2003) Biochem Pharmacol , vol.66 , Issue.8 , pp. 1635-1641
    • Youdim, M.B.1    Amit, T.2    Falach-Yogev, M.3
  • 176
    • 23144441835 scopus 로고    scopus 로고
    • Neuropharmacological, neuroprotective and amyloid precursor processing properties of selective MAO-B inhibitor antiparkinsonian drug, rasagiline
    • Youdim M.B., Maruyama W., and Naoi M. Neuropharmacological, neuroprotective and amyloid precursor processing properties of selective MAO-B inhibitor antiparkinsonian drug, rasagiline. Drugs Today (Barc) 41 6 (2005) 369-391
    • (2005) Drugs Today (Barc) , vol.41 , Issue.6 , pp. 369-391
    • Youdim, M.B.1    Maruyama, W.2    Naoi, M.3
  • 178
    • 0028020079 scopus 로고
    • Neuroprotective effects of some monoamine oxidase-B inhibitors against DSP-4-induced noradrenaline depletion in the mouse hippocampus
    • Yu P.H., Davis B.A., Fang J., et al. Neuroprotective effects of some monoamine oxidase-B inhibitors against DSP-4-induced noradrenaline depletion in the mouse hippocampus. J Neurochem 63 (1994) 1820-1828
    • (1994) J Neurochem , vol.63 , pp. 1820-1828
    • Yu, P.H.1    Davis, B.A.2    Fang, J.3
  • 180
    • 0029938017 scopus 로고    scopus 로고
    • Immunohistochemical evidence of neuroprotection by R(-)-deprenyl and N-(2-hexyl)-N-methylpropargylamine on DSP-4-induced degeneration of rat brain noradrenergic axons and terminals
    • Zhang X., Zuo D.M., Davis B.A., et al. Immunohistochemical evidence of
    • (1996) J Neurosci Res , vol.43 , pp. 482-489
    • Zhang, X.1    Zuo, D.M.2    Davis, B.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.