Chimeric alphavirus vaccine candidates protect mice from intranasal challenge with western equine encephalitis virus

Vaccine

Volumn 27, Issue 32, 2009, Pages 4309-4319

  Atasheva, Svetlana ^a   Wang, Eryu ^a,b   Adams, A Paige ^a,b   Plante, Kenneth S ^a,b   Ni, Sai ^a,b   Taylor, Katherine ^a,b   Miller, Mary E ^a   Frolov, Ilya ^a,b   Weaver, Scott C ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Alphavirus; Vaccine; Virulence; Western equine encephalitis virus

Indexed keywords

GLYCOPROTEIN; LIVE VACCINE; NEUTRALIZING ANTIBODY; NONSTRUCTURAL PROTEIN 1; SIN/CO92 VACCINE; SIN/EEE/MCM VACCINE; SIN/SIN/MCM VACCINE; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG; VIRUS VACCINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; CELL CULTURE; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; FEMALE; IMMUNITY; IMMUNIZATION; IMMUNOGENICITY; IN VITRO STUDY; MAMMAL; MOSQUITO; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROVOCATION TEST; RNA BINDING; SINDBIS VIRUS; VACCINATION; VIRUS CAPSID; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE; WESTERN EQUINE ENCEPHALOMYELITIS ALPHAVIRUS;

ANIMALS; ANTIBODIES, VIRAL; CELL LINE; CRICETINAE; ENCEPHALITIS VIRUS, WESTERN EQUINE; ENCEPHALOMYELITIS, EQUINE; FEMALE; GENETIC VECTORS; GENOME, VIRAL; MICE; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; PREGNANCY; RECOMBINATION, GENETIC; SEQUENCE ANALYSIS, DNA; SINDBIS VIRUS; SURVIVAL ANALYSIS; VACCINES, ATTENUATED; VIRAL NONSTRUCTURAL PROTEINS; VIRAL STRUCTURAL PROTEINS; VIRAL VACCINES;

EID: 67649472422     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.05.011     Document Type: Article

References (30)

1. Reisen W.K. Western equine encephalitis. In: Service M.W. (Ed). The encyclopedia of arthropod-transmitted infections (2001), CAB International, Wallingford, UK 558-563
2. Schlesinger S., and Schlesinger M.J. Togaviridae: the viruses and their replication. In: Knipe D.M., and Howley P.M. (Eds). Fields' virology. 4th ed. (2001), Lippincott, Williams and Wilkins, New York 895-916
3. Weaver S.C., Kang W., Shirako Y., Rumenapf T., Strauss E.G., and Strauss J.H. Recombinational history and molecular evolution of western equine encephalomyelitis complex alphaviruses. Journal of Virology 71 1 (1997) 613-623
4. Reisen W.K., and Monath T.P. Western equine encephalomyelitis. In: Monath T.P. (Ed). The arboviruses: epidemiology and ecology vol. V (1988), CRC Press, Boca Raton, FL 89-137
5. Reed D.S., Larsen T., Sullivan L.J., Lind C.M., Lackemeyer M.G., Pratt W.D., et al. Aerosol exposure to western equine encephalitis virus causes fever and encephalitis in cynomolgus macaques. The Journal of Infectious Diseases 192 7 (2005) 1173-1182
6. Sidwell R.W., and Smee D.F. Viruses of the Bunya- and Togaviridae families: potential as bioterrorism agents and means of control. Antiviral Research 57 1-2 (2003) 101-111
7. Nagata L.P., Hu W.G., Masri S.A., Rayner G.A., Schmaltz F.L., Das D., et al. Efficacy of DNA vaccination against western equine encephalitis virus infection. Vaccine 23 17-18 (2005) 2280-2283
8. Wu J.Q., Barabe N.D., Chau D., Wong C., Rayner G.R., Hu W.G., et al. Complete protection of mice against a lethal dose challenge of western equine encephalitis virus after immunization with an adenovirus-vectored vaccine. Vaccine 25 22 (2007) 4368-4375
9. Barabe N.D., Rayner G.A., Christopher M.E., Nagata L.P., and Wu J.Q. Single-dose, fast-acting vaccine candidate against western equine encephalitis virus completely protects mice from intranasal challenge with different strains of the virus. Vaccine 25 33 (2007) 6271-6276
10. Kostense S., Koudstaal W., Sprangers M., Weverling G.J., Penders G., Helmus N., et al. Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector. AIDS 18 8 (2004) 1213-1216
11. Vogels R., Zuijdgeest D., van Rijnsoever R., Hartkoorn E., Damen I., de Bethune M.P., et al. Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity. Journal of Virology 77 15 (2003) 8263-8271
12. Mane V.P., Toietta G., McCormack W.M., Conde I., Clarke C., Palmer D., et al. Modulation of TNFalpha, a determinant of acute toxicity associated with systemic delivery of first-generation and helper-dependent adenoviral vectors. Gene Therepy 13 17 (2006) 1272-1280
13. Pedersen Jr. C.E., Robinson D.M., and Cole Jr. F.E. Isolation of the vaccine strain of Venezuelan equine encephalomyelitis virus from mosquitoes in Louisiana. American Journal of Epidemiology 95 5 (1972) 490-496
14. Paessler S., Fayzulin R.Z., Anishchenko M., Greene I.P., Weaver S.C., and Frolov I. Recombinant Sindbis/Venezuelan equine encephalitis virus is highly attenuated and immunogenic. Journal of Virology 77 17 (2003) 9278-9286
15. Paessler S., Ni H., Petrakova O., Fayzulin R.Z., Yun N., Anishchenko M., et al. Replication and clearance of Venezuelan equine encephalitis virus from the brains of animals vaccinated with chimeric SIN/VEE viruses. Journal of Virology 80 6 (2006) 2784-2796
16. Wang E., Petrakova O., Adams A.P., Aguilar P.V., Kang W., Paessler S., et al. Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice. Vaccine 25 43 (2007) 7573-7581
17. McKnight K.L., Simpson D.A., Lin S.C., Knott T.A., Polo J.M., Pence D.F., et al. Deduced consensus sequence of Sindbis virus strain AR339: mutations contained in laboratory strains which affect cell culture and in vivo phenotypes. Journal of Virology 70 3 (1996) 1981-1989
18. Aguilar P.V., Adams A.P., Wang E., Kang W., Carrara A.S., Anishchenko M., et al. Structural and nonstructural protein genome regions of eastern equine encephalitis virus are determinants of interferon sensitivity and murine virulence. Journal of Virology 82 10 (2008) 4920-4930
19. Liljeström P., Lusa S., Huylebroeck D., and Garoff H. In vitro mutagenesis of a full-length cDNA clone of Semliki Forest virus: the small 6000-molecular-weight membrane protein modulates virus release. Journal of Virology 65 (1991) 4107-4113
20. Lemm J.A., Durbin R.K., Stollar V., and Rice C.M. Mutations which alter the level or structure of nsP4 can affect the efficiency of Sindbis virus replication in a host-dependent manner. Journal of Virology 64 (1990) 3001-3011
21. Beaty B.J., Calisher C.H., Shope R.E., and Arboviruses. In: Lennete E.T., and Lennete D.A. (Eds). Diagnostic procedures for viral, rickettsial and chlamydial infections. 7th ed. (1995), American Public Health Association, Washington, DC 189-212
22. Bianchi T.I., Aviles G., and Sabattini M.S. Biological characteristics of an enzootic subtype of western equine encephalomyelitis virus from Argentina. Acta Virologica 41 1 (1997) 13-20
23. Hardy J.L., Presser S.B., Chiles R.E., and Reeves W.C. Mouse and baby chicken virulence of enzootic strains of western equine encephalomyelitis virus from California. The American Journal of Tropical Medicine and Hygiene 57 2 (1997) 240-244
24. Forrester N.L., Kenney J.L., Deardorff E., Wang E., and Weaver S.C. Western equine encephalitis submergence: lack of evidence for a decline in virus virulence. Virology 380 2 (2008) 170-172
25. Nagata L.P., Hu W.G., Parker M., Chau D., Rayner G.A., Schmaltz F.L., et al. Infectivity variation and genetic diversity among strains of Western equine encephalitis virus. The Journal of General Virology 87 Pt 8 (2006) 2353-2361
26. Netolitzky D.J., Schmaltz F.L., Parker M.D., Rayner G.A., Fisher G.R., Trent D.W., et al. Complete genomic RNA sequence of western equine encephalitis virus and expression of the structural genes. The Journal of General Virology 81 Pt 1 (2000) 151-159
27. Wang E., Volkova E., Adams A.P., Forrester N., Xiao S.Y., Frolov I., et al. Chimeric alphavirus vaccine candidates for chikungunya. Vaccine 26 39 (2008) 5030-5039
28. Barber T.L., Walton T.E., and Lewis K.J. Efficacy of trivalent inactivated encephalomyelitis virus vaccine in horses. American Journal of Veterinary Research 39 4 (1978) 621-625
29. Pittman P.R., Makuch R.S., Mangiafico J.A., Cannon T.L., Gibbs P.H., and Peters C.J. Long-term duration of detectable neutralizing antibodies after administration of live-attenuated VEE vaccine and following booster vaccination with inactivated VEE vaccine. Vaccine 14 4 (1996) 337-343
30. Liu C., Voth D.W., Rodina P., Shauf L.R., and Gonzalez G. A comparative study of the pathogenesis of western equine and eastern equine encephalomyelitis viral infections in mice by intracerebral and subcutaneous inoculations. The Journal of Infectious Diseases 122 1 (1970) 53-63