Promoter methylation patterns of ATM, ATR, BRCA1, BRCA2 and P53 as putative cancer risk modifiers in Jewish BRCA1/BRCA2 mutation carriers

Breast Cancer Research and Treatment

Volumn 116, Issue 1, 2009, Pages 195-200

  Kontorovich, Tair ^a,b   Cohen, Yoram ^c   Nir, Uri ^b   Friedman, Eitan ^a,d  

^a GERTNER INSTITUTE FOR EPIDEMIOLOGY AND HEALTH POLICY RESEARCH   (Israel)

^b BAR ILAN UNIVERSITY   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

BRCA1 BRCA2; Cancer susceptibility; Epigenetic mechanisms; Methylation; Modifier genes

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BRCA1 PROTEIN; BRCA2 PROTEIN; PROTEIN P53;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER RISK; CONTROLLED STUDY; DNA HYPERMETHYLATION; DNA METHYLATION; EPIGENETICS; FEMALE; GENE MUTATION; GERM LINE; GROUPS BY AGE; HETEROZYGOTE; HUMAN; JEW; MAJOR CLINICAL STUDY; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; TUMOR SUPPRESSOR GENE;

ADULT; AGE FACTORS; BREAST NEOPLASMS; CELL CYCLE PROTEINS; DNA METHYLATION; DNA-BINDING PROTEINS; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; ISRAEL; MIDDLE AGED; OVARIAN NEOPLASMS; PROMOTER REGIONS, GENETIC; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 67649452451     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-008-0121-3     Document Type: Article

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