Dietary garlic and onion reduce the incidence of atherogenic diet-induced cholesterol gallstones in experimental mice

British Journal of Nutrition

Volumn 101, Issue 11, 2009, Pages 1621-1629

  Vidyashankar, Satyakumar ^a   Sambaiah, Kari ^a   Srinivasan, Krishnapura ^a  

^a CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

Author keywords

Cholesterol gallstones; Cholesterol saturation index; Dietary garlic; Dietary onion; Hydrophobicity index

Indexed keywords

BILE ACID; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; PHOSPHOLIPID; STEROL 27 HYDROXYLASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLELITHIASIS; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL STONE; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVITY; EXPERIMENTAL MOUSE; FOOD ANALYSIS; GALLSTONE; GARLIC; HYDROPHOBICITY; HYPERCHOLESTEROLEMIA; INCIDENCE; LIVER LEVEL; MALE; MOUSE; NONHUMAN; ONION;

ANIMALS; BILE; CHOLELITHIASIS; CHOLESTEROL; DIET; DIET, ATHEROGENIC; DISEASE MODELS, ANIMAL; GARLIC; HYDROPHOBICITY; LIPID METABOLISM; LIVER; MALE; MICE; ONIONS;

ALLIUM; ALLIUM CEPA; ALLIUM SATIVUM; MUS;

EID: 67649450073     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508118748     Document Type: Article

References (46)

1. Johnston DE & Kaplan MM (1993) Pathogenesis and treatment of gallstones. N Engl J Med 328, 412-421.
2. Juvonen T (1994) Pathogenesis of gallstones. Scand J Gastroenterol 29, 577-582.
3. Apstein MD & Carey MC (1996) Pathogenesis of cholesterol gallstones - a parsimonious hypothesis. Eur J Clin Invest 26, 343-352.
4. Marzolo MP, Rigotti A & Nervi F (1990) Secretion of biliary lipids from the hepatocyte. Hepatology 12, Suppl., 134-142.
5. Ozben T (1989) Biliary lipids, composition and gallstone formation in rabbits fed on soya protein, cholesterol, casein and modified casein. Biochem J 263, 293-296.
6. Scobey MW, Johnson FL, Parks JS, et al. (1991) Dietary fish oil effects on biliary lipid secretion and cholesterol gallstone formation in the African green monkeys. Hepatology 14, 679-684.
7. Judd PA (1985) Dietary fibre and gallstones. In Dietary Fibre Perspective: Reviews and Bibliography, pp. 40-46 [AR Leeds, editor]. London: John Libbey.
8. Ebihara K & Kiriyama S (1985) Prevention of CGS by a water soluble fibre - Konjac Mannan in mice. Nutr Rep Int 32, 223-229.
9. Srinivasan K, Sambaiah K & Chandrasekhara N (2004) Spices as beneficial hypochole-sterolemic food adjuncts: A review. Food Rev Int 20 187-220.
10. Hussain MS & Chandrasekhara N (1993) Influence of curcumin and capsaicin on cholesterol gallstone induction in hamsters and mice. Nutr Res 13, 349-357.
11. Hussain MS & Chandrasekhara N (1994) Effect of curcumin and capsaicin on the regression of pre-established CGS in mice. Nutr Res 14, 1561-1574.
12. Suresh D, Manjunatha H & Srinivasan K (2007) Effect of heat processing of spices on the concentrations of their bioactive principles: Turmeric (Curcuma longa), red pepper (Capsicum annuum) and black pepper (Piper nigrum). J Food Comp Anal 20, 346-351.
13. Bligh EG & Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37, 911-917.
14. Turley SD & Dietschy JM (1970) Reevaluation of 3α-hydroxysteroid dehydrogenase assay for total bile acids. J Lipid Res 19, 924-928.
15. Folch J, Lees M & Sloane-Stanley GH (1957) A simple method for the isolation and purification of total lipids from animal tissue. J Biol Chem 226, 497-509.
16. Searcy RL & Bergquist LM (1960) A new colour reaction for the quantification of serum cholesterol. Clin Chim Acta 5, 192-199.
17. Charles J & Stewart M (1980) Colorimetric estimation of phospholipids with ammonium ferrothiocyanate. Anal Biochem 104, 10-14.
18. Fletcher MJ (1968) A colorimetric method for estimating serum triglycerides. Clin Chim Acta 22, 303-307.
19. Rosi SS, Converse JL & Hofmann AF (1987) High pressure liquid chromatographic analysis of conjugated bile acids in human bile: simultaneous resolution of sulfated and unsulfated lithocholyl amidates and the common conjugated bile acids. J Lipid Res 28, 589-595.
20. Heuman DM (1989) Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions. J Lipid Res 30, 719-730.
21. Carey MC (1978) Critical tables for calculating the cholesterol saturation of native bile. J Lipid Res 19, 945-955.
22. Morrison MR & Smith M (1964) Preparation of fatty acid methyl esters and dimethyl acetyls from lipids with boron trifluoride methanol. J Lipid Res 5, 600-608.
23. Hulcher FH & Oleson WH (1973) Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase by measurement of coenzyme-A. J Lipid Res 14, 625-631.
24. Petrack B & Latario BJ (1993) Synthesis of 27-hydroxycholesterol in rat liver mitochondria: HPLC assay and marked activation by exogenous cholesterol. J Lipid Res 34, 643-649.
25. Lowry OH, Rosebrough NJ, Farr AL, et al. (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193, 265-275.
26. Tepperman J, Cladwell FT & Tepperman HM (1964) Induction of gallstones in mice by feeding a cholesterol and cholic acid containing diet. Am J Physiol 206, 628-638.
27. Bhat GB, Srinivasan MR & Chandrasekhara N (1984) Influence of curcumin and capsaicin on bile secretion and composition in the rat. J Food Sci Technol 21, 225-227.
28. Bhat GB, Sambaiah K & Chandrasekhara N (1985) The effect of feeding fenugreek and ginger on bile composition in the albino rat. Nutr Rep Int 32, 1145-1151.
29. Sambaiah K & Srinivasan K (1991) Secretion and composition of bile in rats fed diets containing spices. J Food Sci Technol 28, 35-38.
30. Platel K & Srinivasan K (2000) Stimulatory influence of select spices on bile secretion in rats. Nutr Res 20, 1493-1503.
31. van Erpecum KJ & van Berge-Henegouwen GP (1989) Pathogenic factors in cholesterol gallstone disease. Scand J Gastroenterol 24, Suppl., 83-90.
32. Thimmayamma BVS, Rao P & Radhaiah G (1983) Use of spices and condiments in the dietaries of urban and rural families. Indian J Nutr Dietet 20, 153-162.
33. Wang DQH, Lammert F, Paigen B, et al. (1999) Phenotypic characterization of lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: Pathophysiology of biliary lipid secretion. J Lipid Res 40, 2066-2079.
34. Carey MC & Small DM (1978) The physical chemistry of cholesterol solubility in bile: Relationship to gallstone formation and dissolution in man. J Clin Invest 61, 998-1026.
35. Robins SJ, Fasulo JM, Robins VF, et al. (1991) Utilization of different fatty acids for hepatic and biliary PC formation and the effect of changes in PC molecular species on biliary lipid structures. J Lipid Res 32, 985-992.
36. Hoffmann AF & Grundy SM (1982) Pretreatment biliary lipid composition in white patients with radiolucent gallstones in the National Cooperative Gallstone Study. Gastroenterology 83, 738-752.
37. Knox R, Stein I, Levinson D, et al. (1991) Effect of fat prefeeding on bile flow and composition in the rat. Biochim Biophys Acta 1083, 65-70.
38. Tierney S, Ahrendt SA, Fox K, et al. (1993) Fish oil reduces biliary cholesterol and prolongs nucleation of human gallbladder bile. Gastroenterology 104, 380-384.
39. Cohen DE, Angelico M & Carey MC (1990) Structural alteration in lecithin-cholesterol vesicles following interactions with monomeric and micellar bile salts: Physical-chemical basis for sub selection of biliary lipids during bile formation. J Lipid Res 31, 55-70.
40. Roslyn JJ, Doty J, Pitt HA, et al. (1986) Enhanced gallbladder absorption during gallstone formation: The roles of cholesterol saturated bile and gallbladder stasis. Am J Med Sci 292, 75-80.
41. Afdhal NH & Smith BF (1990) Cholesterol crystal nucleation: A decade long search for the missing link in gallstone pathogenesis. Hepatology 11, 699-702.
42. Armstrong MJ & Carey MC (1982) The hydrophobic-hydrophilic balance of bile salts: Inverse correlation between reverse-phase high performance liquid chromatographic metabolites and micellar cholesterol solubilizing capacities. J Lipid Res 23, 70-80.
43. Berr F, Holl J, Jungst D, et al. (1992) Dietary n-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease. Hepatology 16, 960-967.
44. Dietschy JM, Turley SD & Spady DK (1993) Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J Lipid Res 34, 1637-1659.
45. Srinivasan K & Sambaiah K (1991) The effect of spices on cholesterol 7α-hydroxylase activity and on serum hepatic cholesterol levels in the rats. Int J Vit Nutr Res 61, 364-369.
46. Kamanna VS & Chandrasekhara N (1984) Hypocholesterolemic activity of different fractions of garlic. Indian J Med Res 9, 580-583.